PB1-F2 Finder: Scanning influenza sequences for PB1-F2 encoding RNA segments

BMC Bioinformatics

Volumn 12, Issue SUPPL. 13, 2011, Pages

  DeLuca, David S ^a,b   Keskin, Derin B ^a   Zhang, Guang L ^a   Reinherz, Ellis L ^a   Brusic, Vladimir ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2009 H1N1; 20TH CENTURY; INFLUENZA PANDEMICS; INFLUENZA SEQUENCES; STOP CODONS; SUBSTANTIAL VARIATIONS; VIRULENCE FACTORS; DATA SETS;

PROTEINS; RNA; ENCODING (SYMBOLS);

ENCODING (SYMBOLS); BIOINFORMATICS;

SUIDAE;

INFLUENZA VIRUS POLYMERASE BASIC PROTEIN 1; VIRULENCE FACTOR; VIRUS PROTEIN;

ALGORITHM; ARTICLE; GENETICS; HUMAN; INFLUENZA; INFLUENZA VIRUS A; INFLUENZA VIRUS A H1N1; PATHOGENICITY; SEQUENCE ANALYSIS; VIROLOGY;

ALGORITHMS; HUMANS; INFLUENZA A VIRUS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; SEQUENCE ANALYSIS, RNA; VIRAL PROTEINS; VIRULENCE FACTORS;

EID: 84864066458     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-12-S13-S6     Document Type: Article

References (10)

1. Cox NJ, Subbarao K. Global epidemiology of influenza: past and present. Annu Rev Med 2000, 51:407-421. 10.1146/annurev.med.51.1.407, 10774473.
2. Chen W, Calvo PA, Malide D, Gibbs J, Schubert U, Bacik I, Basta S, O'Neill R, Schickli J, Palese P, Henklein P, Bennink JR, Yewdell JW. A novel influenza A virus mitochondrial protein that induces cell death. Nat Med 2001, 7:1306-1312. 10.1038/nm1201-1306, 11726970.
3. Coleman JR. The PB1-F2 protein of Influenza A virus: increasing patho-genicity by disrupting alveolar macrophages. Virol J 2007, 4:9. 10.1186/1743-422X-4-9, 1781424, 17224071.
4. Yamada H, Chounan R, Higashi Y, Kurihara N, Kido H. Mitochon-drial targeting sequence of the influenza A virus PB1-F2 protein and its function in mitochondria. FEBS Lett 2004, 578:331-336. 10.1016/j.febslet.2004.11.017, 15589841.
5. Zell R, Krumbholz A, Eitner A, Krieg R, Halbhuber KJ, Wutzler P. Prevalence of PB1-F2 of influenza A viruses. J Gen Virol 2007, 88:536-546. 10.1099/vir.0.82378-0, 17251572.
6. McAuley JL, Zhang K, McCullers JA. The effects of influenza A virus PB1-F2 protein on polymerase activity are strain specific and do not impact patho-genesis. J Virol 2010, 84:558-564. 10.1128/JVI.01785-09, 2798424, 19828614.
7. Bao Y, Bolotov P, Dernovoy D, Kiryutin B, Zaslavsky L, Tatusova T, Ostell J, Lipman D. The influenza virus resource at the National Center for Biotechnology Information. J Virol 2008, 82:596-601. 10.1128/JVI.02005-07, 2224563, 17942553.
8. Noble S, Dimmock NJ. Characterization of putative defective interfering (DI) A/WSN RNAs isolated from the lungs of mice protected from an otherwise lethal respiratory infection with influenza virus A/WSN (H1N1): a subset of the inoculum DI RNAs. Virology 1995, 210:9-19. 10.1006/viro.1995.1312, 7793084.
9. Kim HM, Oh JH, Seo SH. Genetic characterization of avian influenza viruses isolated from waterfowl in southern part of South Korea in 2006. Virus Genes 2008, 37:49-51. 10.1007/s11262-008-0230-4, 18425571.
10. Heiny AT, Miotto O, Srinivasan KN, Khan AM, Zhang GL, Brusic V, Tan TW, August JT. Evolutionarily conserved protein sequences of influenza a viruses, avian and human, as vaccine targets. PLoS One 2007, 2:e1190. 10.1371/journal.pone.0001190, 2065905, 18030326.