FLT3-regulated antigens as targets for leukemia-reactive cytotoxic T lymphocytes

Blood Cancer Journal

Volumn 1, Issue 3, 2011, Pages

  Brackertz, B ^a   Conrad, H ^a   Daniel, J ^a   Kast, B ^a,b   Kronig H ^a   Busch, D H ^b,c   Adamski, J ^b,d   Peschel, C ^a   Bernhard, H ^a,b,e  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e KLINIKUM DARMSTADT   (Germany)

Author keywords

Acute myeloid leukemia; FLT3 kinase; Immunotherapy; Leukemiaassociated antigens; T cell clones

Indexed keywords

BCR ABL PROTEIN; CD135 ANTIGEN; MYELOBLASTIN; RHAMM PROTEIN; SMALL INTERFERING RNA; SURVIVIN; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; IMMUNOTHERAPY; MOLECULAR CLONING; PROTEIN EXPRESSION; UPREGULATION;

EID: 84864045910     PISSN: None     EISSN: 20445385     Source Type: Journal    
DOI: 10.1038/bcj.2011.12     Document Type: Article

References (8)

1. Yamashita Y, Yuan J, Suetake I, Suzuki H, Ishikawa Y, Choi YL et al. Array-based genomic resequencing of human leukemia. Oncogene 2010; 29: 3723-3731.
2. Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med 2010; 363: 2424-2433.
3. Galili N, Raza A. Pharmacotherapy of myelodysplastic syndromes. Expert Opin Pharmacother 2010; 11: 1889-1899.
4. Garcia-Manero G. Demethylating agents in myeloid malignancies. Curr Opin Oncol 2008; 20: 705-710.
5. Jones PA, Liang G. Rethinking how DNA methylation patterns are maintained. Nat Rev Genet 2009; 10: 805-811.
6. Xu F, Li X, Wu L, Zhang Q, Yang R, Yang Y et al. Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring. Ann Hematol 2010 (e-pub ahead of print 2 December 2010).
7. Mori N, Yoshinaga K, Tomita K, Ohwashi M, Kondoh T, Shimura H et al. Aberrant methylation of the RIZ1 gene in myelodysplastic syndrome and acute myeloid leukemia. Leuk Res 2010 (e-pub ahead of print 7 September 2010).
8. Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128: 683-692. (Pubitemid 46273572)