Protein scaffolds can enhance the bistability of multisite phosphorylation systems

PLoS Computational Biology

Volumn 8, Issue 6, 2012, Pages

  Chan, Carlo ^a   Liu, Xinfeng ^b   Wang, Liming ^c   Bardwell, Lee ^a   Nie, Qing ^a   Enciso, Germán ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTH CAROLINA   (United States)

^c CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; ENZYMES; SCAFFOLDS (BIOLOGY);

BI-STABILITY; CONDITION; KINASE ENZYMES; MULTI-SITE; PROTEIN KINASE; PROTEIN MODIFICATIONS; PROTEIN PHOSPHORYLATION; PROTEIN SCAFFOLDS; SCAFFOLD PROTEIN; TARGET-SUBSTRATE;

PHOSPHORYLATION;

SCAFFOLD PROTEIN; PROTEIN; PROTEIN KINASE;

ALGORITHM; ARTICLE; BINDING SITE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYMATIC ASSAY; ENZYME ACTIVATION; ENZYME ACTIVITY; LINEAR SYSTEM; MATHEMATICAL ANALYSIS; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MOLECULAR INTERACTION; PROTEIN CONFORMATION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; REACTION ANALYSIS; BIOLOGICAL MODEL; BIOLOGY; CHEMISTRY; COMPUTER SIMULATION; KINETICS; METABOLISM; PHOSPHORYLATION; PROTEIN PROCESSING; STATISTICAL MODEL;

BINDING SITES; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; KINETICS; LINEAR MODELS; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STABILITY; PROTEINS;

EID: 84864033851     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002551     Document Type: Article

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