Metabolomic investigations of Ricinus communis for cultivar and provenance determination

Metabolomics

Volumn 8, Issue 4, 2012, Pages 634-642

  Pigott, Eloise J ^a   Roberts, Warren ^a   Ovenden, Simon P B ^a   Rochfort, Simone ^b,c   Bourne, David J ^a  

^a DEFENCE SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^b LA TROBE UNIVERSITY   (Australia)

^c LA TROBE UNIVERSITY   (Australia)

Author keywords

Cultivar; Metabolomics; Provenance; Ricin; Ricinus communis

Indexed keywords

MOLECULAR MARKER; N DEMETHYL RICININE; O DEMETHYL RICININE; PHENYLALANINE; RICIN; RICININE; RICINUS COMMUNIS EXTRACT; SUCROSE; UNCLASSIFIED DRUG;

ARTICLE; CULTIVAR; CULTIVAR IDENTIFICATION; DISCRIMINANT ANALYSIS; INFRASPECIFIC RANK; MATHEMATICAL MODEL; METABOLOMICS; NONHUMAN; PARTIAL LEAST SQUARES REGRESSION; PHYTOCHEMISTRY; PLANT IDENTIFICATION; PREDICTION; PROTON NUCLEAR MAGNETIC RESONANCE; PROVENANCE; RICINUS COMMUNIS;

RICINUS COMMUNIS;

EID: 84864026739     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-011-0355-7     Document Type: Article

References (18)

1. Audi, J., Belson, M., Patel, M., Schier, J., & Osterloh, J. (2005). Ricin poisoning: A comprehensive review. Journal of the American Medical Association, 294, 2342-2351.
2. Bradberry, S. M., Dickers, K. J., Rice, P., Griffiths, G. D., & Vale, J. A. (2003). Ricin poisoning. Toxicological Review, 22, 65-70.
3. Brinkworth, C. S. (2010). Identification of ricin in crude and purified extracts from castor beans using on-target tryptic digestion and MALDI mass spectrometry. Analytical Chemistry, 82, 5246-5252.
4. Brinkworth, C. S., Pigott, E. J., & Bourne, D. J. (2009). Detection of intact ricin in crude and purified extracts from castor beans using matrix-assisted laser desorption ionisation mass spectrometry. Analytical Chemistry, 81, 1529-1535.
5. 1H NMR spectroscopy and principal component analysis. Journal of Natural Products, 67, 953-957.
6. Darby, S. M., Miller, M. L., & Allen, R. O. (2001). Forensic determination of ricin and the alkaloid marker ricinine from castor bean extracts. Journal of Forensic Science, 46, 1033-1042.
7. 1H NMR metabonomics. Analytical Chemistry, 78, 4281-4290.
8. Dunn, W. B., Bailey, N. J. C., & Johnson, H. E. (2005). Measuring the metabolome: Current analytical technologies. Analyst, 13, 606-625.
9. Fredriksson, S. Å., Hulst, A. G., Artursson, E., de Jong, A. L., & van Baar, B. L. M. (2005). Forensic identification of neat ricin and of ricin from crude castor bean extracts by mass spectrometry. Analytical Chemistry, 77, 1545-1555.
10. Hamzehzarghani, H., Kushalappa, A. C., Dion, Y., Rioux, S., Comeau, A., Yaylayan, V., et al. (2005). Metabolic profiling and factor analysis to discriminate quantitative resistance in wheat cultivars against fusarium head blight. Physiological and Molecular Plant Pathology, 66, 119-133.
11. Krishnan, P., & Kruger, N. J. (2005). Metabolite fingerprinting and profiling in plants using NMR. Journal of Experimental Botany, 56, 255-265.
12. Makris, D. P., Kallithraka, S., & Mamalos, A. (2006). Differentiation of young red wines based on cultivar and geographical origin with application of chemometrics of principal polyphenolic constituents. Talanta, 70, 1143-1152.
13. Millard, C. B., & LeClaire, R. D. (2008). Ricin and related toxins: Review and perspective in Chemical warfare agents; chemistry, pharmacology, toxicology and therapeutics (pp. 423-467). Boca Raton: CRC Press; Taylor & Francis Group.
14. Musshoff, F., & Madea, B. (2009). Ricin poisoning and forensic toxicology. Drug Testing and Analysis, 1, 184-191.
15. Ovenden, S. P. B., Fredriksson, S. Å., Bagas, C. K., Bergström, T., Thomson, S. A., Nilsson, C., et al. (2009). De novo sequencing of RCB-1 to -3: Peptide biomarkers from the castor bean plant Ricinus communis. Analytical Chemistry, 81, 3986-3996.
16. Parsons, H. M., Ludwig, C., Günther, U. L., & Viant, M. R. (2007). Improved classification accuracy in 1- and 2-dimensional NMR metabolomics data using the variance stabilising generalised logarithm transformation. BMC Bioinformatics, 8, 234.
17. United Nations. (1992). Convention on the prohibition of the development, production, stockpiling and use of chemical weapons and on their destruction, Geneva. Retrieved July 5, 2011 from http://www. dfat. gov. au/cwco/download/index. htm.
18. Viant, M. R. (2003). Improved methods for the acquisition and interpretation of NMR metabolomic data. Biochemical and Biophysical Research Communications, 310, 943-948.