메뉴 건너뛰기




Volumn 12, Issue 13, 2012, Pages 2212-2220

Diverse monoclonal antibodies against the CA 19-9 antigen show variation in binding specificity with consequences for clinical interpretation

Author keywords

Antibody microarrays; Biomarkers; Biomedicine; Cancer; Carbohydrates; Glycomics

Indexed keywords

BIOLOGICAL MARKER; CA 19-9 ANTIGEN; EPITOPE; GLYCAN; MONOCLONAL ANTIBODY; SIALYL LEWIS X ANTIGEN;

EID: 84864005063     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201100676     Document Type: Article
Times cited : (39)

References (39)
  • 1
    • 33947668471 scopus 로고    scopus 로고
    • Systematic review of carbohydrate antigen (CA 19-9) as a biochemical marker in the diagnosis of pancreatic cancer
    • Goonetilleke, K. S., Siriwardena, A. K., Systematic review of carbohydrate antigen (CA 19-9) as a biochemical marker in the diagnosis of pancreatic cancer. Eur. J. Surg. Oncol. 2007, 33, 266-270.
    • (2007) Eur. J. Surg. Oncol. , vol.33 , pp. 266-270
    • Goonetilleke, K.S.1    Siriwardena, A.K.2
  • 2
    • 84863596203 scopus 로고    scopus 로고
    • CA 19-9 in pancreatic cancer: retrospective evaluation of patients with suspicion of pancreatic cancer
    • Molina, V., Visa, L., Conill, C., Navarro, S. et al., CA 19-9 in pancreatic cancer: retrospective evaluation of patients with suspicion of pancreatic cancer. Tumour Biol. 2012, 33, 799-807.
    • (2012) Tumour Biol. , vol.33 , pp. 799-807
    • Molina, V.1    Visa, L.2    Conill, C.3    Navarro, S.4
  • 3
    • 0023637227 scopus 로고
    • Relationship of carbohydrate antigen 19-9 and Lewis antigens in pancreatic cancer
    • Tempero, M. A., Uchida, E., Takasaki, H., Burnett, D. A. et al., Relationship of carbohydrate antigen 19-9 and Lewis antigens in pancreatic cancer. Cancer Res. 1987, 47, 5501-5503.
    • (1987) Cancer Res. , vol.47 , pp. 5501-5503
    • Tempero, M.A.1    Uchida, E.2    Takasaki, H.3    Burnett, D.A.4
  • 4
    • 77952973346 scopus 로고    scopus 로고
    • Predictive and prognostic value of CA 19-9 in resected pancreatic adenocarcinoma
    • Barton, J. G., Bois, J. P., Sarr, M. G., Wood, C. M. et al., Predictive and prognostic value of CA 19-9 in resected pancreatic adenocarcinoma. J. Gastrointest. Surg. 2009, 13, 2050-2058.
    • (2009) J. Gastrointest. Surg. , vol.13 , pp. 2050-2058
    • Barton, J.G.1    Bois, J.P.2    Sarr, M.G.3    Wood, C.M.4
  • 5
    • 0031056804 scopus 로고    scopus 로고
    • CA 19-9 in evaluating the response to chemotherapy in advanced pancreatic cancer
    • Ishii, H., Okada, S., Sato, T., Wakasugi, H. et al., CA 19-9 in evaluating the response to chemotherapy in advanced pancreatic cancer. Hepato-gastroenterology 1997, 44, 279-283.
    • (1997) Hepato-gastroenterology , vol.44 , pp. 279-283
    • Ishii, H.1    Okada, S.2    Sato, T.3    Wakasugi, H.4
  • 6
    • 0038199686 scopus 로고    scopus 로고
    • CA 19-9 in the therapy monitoring and follow-up of locally advanced cancer of the exocrine pancreas treated with radiochemotherapy
    • Micke, O., Bruns, F., Schafer, U., Kurowski, R. et al., CA 19-9 in the therapy monitoring and follow-up of locally advanced cancer of the exocrine pancreas treated with radiochemotherapy. Anticancer Res. 2003, 23, 835-840.
    • (2003) Anticancer Res. , vol.23 , pp. 835-840
    • Micke, O.1    Bruns, F.2    Schafer, U.3    Kurowski, R.4
  • 7
    • 38549176328 scopus 로고    scopus 로고
    • CA 19-9 tumour-marker response to chemotherapy in patients with advanced pancreatic cancer enrolled in a randomised controlled trial
    • Hess, V., Glimelius, B., Grawe, P., Dietrich, D. et al., CA 19-9 tumour-marker response to chemotherapy in patients with advanced pancreatic cancer enrolled in a randomised controlled trial. Lancet Oncol. 2008, 9, 132-138.
    • (2008) Lancet Oncol. , vol.9 , pp. 132-138
    • Hess, V.1    Glimelius, B.2    Grawe, P.3    Dietrich, D.4
  • 8
    • 76049118450 scopus 로고    scopus 로고
    • Application of a time-varying covariate model to the analysis of CA 19-9 as serum biomarker in patients with advanced pancreatic cancer
    • Boeck, S., Haas, M., Laubender, R. P., Kullmann, F. et al., Application of a time-varying covariate model to the analysis of CA 19-9 as serum biomarker in patients with advanced pancreatic cancer. Clin. Cancer Res. 2010, 16, 986-994.
    • (2010) Clin. Cancer Res. , vol.16 , pp. 986-994
    • Boeck, S.1    Haas, M.2    Laubender, R.P.3    Kullmann, F.4
  • 10
    • 0028840374 scopus 로고
    • Tumor markers CA 125 and CA 19-9 in cord blood and during infancy: developmental changes and use in pediatric germ cell tumors
    • Lahdenne, P., Pitkanen, S., Rajantie, J., Kuusela, P. et al., Tumor markers CA 125 and CA 19-9 in cord blood and during infancy: developmental changes and use in pediatric germ cell tumors. Pediatr. Res. 1995, 38, 797-801.
    • (1995) Pediatr. Res. , vol.38 , pp. 797-801
    • Lahdenne, P.1    Pitkanen, S.2    Rajantie, J.3    Kuusela, P.4
  • 11
    • 0021027153 scopus 로고
    • Identification of the gastrointestinal and pancreatic cancer-associated antigen detected by monoclonal antibody 19-9 in the sera of patients as a mucin
    • Magnani, J. L., Steplewski, Z., Koprowski, H., Ginsburg, V., Identification of the gastrointestinal and pancreatic cancer-associated antigen detected by monoclonal antibody 19-9 in the sera of patients as a mucin. Cancer Res. 1983, 43, 5489-5492.
    • (1983) Cancer Res. , vol.43 , pp. 5489-5492
    • Magnani, J.L.1    Steplewski, Z.2    Koprowski, H.3    Ginsburg, V.4
  • 12
    • 0022625745 scopus 로고
    • Characterization of CA 19-9 bearing mucins as physiological exocrine pancreatic secretion products
    • Kalthoff, H., Kreiker, C., Schmiegel, W. H., Greten, H. et al., Characterization of CA 19-9 bearing mucins as physiological exocrine pancreatic secretion products. Cancer Res. 1986, 46, 3605-3607.
    • (1986) Cancer Res. , vol.46 , pp. 3605-3607
    • Kalthoff, H.1    Kreiker, C.2    Schmiegel, W.H.3    Greten, H.4
  • 13
    • 80052468511 scopus 로고    scopus 로고
    • Identification of blood-protein carriers of the CA 19-9 antigen and characterization of prevalence in pancreatic diseases
    • Yue, T., Partyka, K., Maupin, K. A., Hurley, M. et al., Identification of blood-protein carriers of the CA 19-9 antigen and characterization of prevalence in pancreatic diseases. Proteomics 2011, 11, 3665-3674.
    • (2011) Proteomics , vol.11 , pp. 3665-3674
    • Yue, T.1    Partyka, K.2    Maupin, K.A.3    Hurley, M.4
  • 14
    • 70349159332 scopus 로고    scopus 로고
    • The prevalence and nature of glycan alterations on specific proteins in pancreatic cancer patients revealed using antibody-lectin sandwich arrays
    • Yue, T., Goldstein, I. J., Hollingsworth, M. A., Kaul, K. et al., The prevalence and nature of glycan alterations on specific proteins in pancreatic cancer patients revealed using antibody-lectin sandwich arrays. Mol. Cell. Proteomics 2009, 8, 1697-1707.
    • (2009) Mol. Cell. Proteomics , vol.8 , pp. 1697-1707
    • Yue, T.1    Goldstein, I.J.2    Hollingsworth, M.A.3    Kaul, K.4
  • 15
    • 34547759863 scopus 로고    scopus 로고
    • High-throughput carbohydrate microarray profiling of 27 antibodies demonstrates widespread specificity problems
    • Manimala, J. C., Roach, T. A., Li, Z., Gildersleeve, J. C., High-throughput carbohydrate microarray profiling of 27 antibodies demonstrates widespread specificity problems. Glycobiology 2007, 17, 17C-23C.
    • (2007) Glycobiology , vol.17
    • Manimala, J.C.1    Roach, T.A.2    Li, Z.3    Gildersleeve, J.C.4
  • 16
    • 0038159832 scopus 로고    scopus 로고
    • Glycobiology. Turning sweet on cancer
    • Alper, J., Glycobiology. Turning sweet on cancer. Science 2003, 301, 159-160.
    • (2003) Science , vol.301 , pp. 159-160
    • Alper, J.1
  • 18
    • 64649101157 scopus 로고    scopus 로고
    • Microarrays in glycoproteomics research
    • Yue, T., Haab, B. B., Microarrays in glycoproteomics research. Clin. Lab. Med. 2009, 29, 15-29.
    • (2009) Clin. Lab. Med. , vol.29 , pp. 15-29
    • Yue, T.1    Haab, B.B.2
  • 19
    • 34547586470 scopus 로고    scopus 로고
    • Low-volume, high-throughput sandwich immunoassays for profiling plasma proteins in mice: identification of early-stage systemic inflammation in a mouse model of intestinal cancer
    • Forrester, S., Kuick, R., Hung, K. E., Kucherlapati, R. et al., Low-volume, high-throughput sandwich immunoassays for profiling plasma proteins in mice: identification of early-stage systemic inflammation in a mouse model of intestinal cancer. Mol. Oncol. 2007, 1, 216-225.
    • (2007) Mol. Oncol. , vol.1 , pp. 216-225
    • Forrester, S.1    Kuick, R.2    Hung, K.E.3    Kucherlapati, R.4
  • 20
    • 0036923229 scopus 로고    scopus 로고
    • Glycan arrays for functional glycomics
    • REVIEWS1034.
    • Drickamer, K., Taylor, M. E., Glycan arrays for functional glycomics. Genome Boil. 2002, 3, REVIEWS1034.
    • (2002) Genome Boil. , vol.3
    • Drickamer, K.1    Taylor, M.E.2
  • 21
    • 10344233222 scopus 로고    scopus 로고
    • Printed covalent glycan array for ligand profiling of diverse glycan binding proteins
    • Blixt, O., Head, S., Mondala, T., Scanlan, C. et al., Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. Proc. Natl. Acad. Sci. U. S.A. 2004, 101, 17033-17038.
    • (2004) Proc. Natl. Acad. Sci. U. S.A. , vol.101 , pp. 17033-17038
    • Blixt, O.1    Head, S.2    Mondala, T.3    Scanlan, C.4
  • 22
    • 80054770301 scopus 로고    scopus 로고
    • High-throughput studies of protein glycoforms using antibody-lectin sandwich arrays
    • Haab, B. B., Yue, T., High-throughput studies of protein glycoforms using antibody-lectin sandwich arrays. Methods Mol. Biol. 2011, 785, 223-236.
    • (2011) Methods Mol. Biol. , vol.785 , pp. 223-236
    • Haab, B.B.1    Yue, T.2
  • 23
    • 77949904604 scopus 로고    scopus 로고
    • A motif-based analysis of glycan array data to determine the specificities of glycan-binding proteins
    • Porter, A., Yue, T., Heeringa, L., Day, S. et al., A motif-based analysis of glycan array data to determine the specificities of glycan-binding proteins. Glycobiology 2010, 20, 369-380.
    • (2010) Glycobiology , vol.20 , pp. 369-380
    • Porter, A.1    Yue, T.2    Heeringa, L.3    Day, S.4
  • 24
    • 0142059844 scopus 로고    scopus 로고
    • Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid
    • Tangvoranuntakul, P., Gagneux, P., Diaz, S., Bardor, M. et al., Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid. Proc. Natl. Acad. Sci U.S.A. 2003, 100, 12045-12050.
    • (2003) Proc. Natl. Acad. Sci U.S.A. , vol.100 , pp. 12045-12050
    • Tangvoranuntakul, P.1    Gagneux, P.2    Diaz, S.3    Bardor, M.4
  • 25
    • 77952798093 scopus 로고    scopus 로고
    • Extensive enrichment of N-glycolylneuraminic acid in extracellular sialoglycoproteins abundantly synthesized and secreted by human cancer cells
    • Inoue, S., Sato, C., Kitajima, K., Extensive enrichment of N-glycolylneuraminic acid in extracellular sialoglycoproteins abundantly synthesized and secreted by human cancer cells. Glycobiology 2010, 20, 752-762.
    • (2010) Glycobiology , vol.20 , pp. 752-762
    • Inoue, S.1    Sato, C.2    Kitajima, K.3
  • 26
    • 79955488798 scopus 로고    scopus 로고
    • Human xeno-autoantibodies against a non-human sialic acid serve as novel serum biomarkers and immunotherapeutics in cancer
    • Padler-Karavani, V., Hurtado-Ziola, N., Pu, M., Yu, H. et al., Human xeno-autoantibodies against a non-human sialic acid serve as novel serum biomarkers and immunotherapeutics in cancer. Cancer Res. 2011, 71, 3352-3363.
    • (2011) Cancer Res. , vol.71 , pp. 3352-3363
    • Padler-Karavani, V.1    Hurtado-Ziola, N.2    Pu, M.3    Yu, H.4
  • 27
    • 0036951996 scopus 로고    scopus 로고
    • Distribution of Lewis (FUT3)genotype and allele: frequencies in a biethnic United States population
    • Cakir, B., Pankow, J. S., Salomaa, V., Couper, D. et al., Distribution of Lewis (FUT3)genotype and allele: frequencies in a biethnic United States population. Ann. Hematol. 2002, 81, 558-565.
    • (2002) Ann. Hematol. , vol.81 , pp. 558-565
    • Cakir, B.1    Pankow, J.S.2    Salomaa, V.3    Couper, D.4
  • 28
    • 0029657913 scopus 로고    scopus 로고
    • Influence of Lewis alpha1-3/4-L-fucosyltransferase (FUT3) gene mutations on enzyme activity, erythrocyte phenotyping, and circulating tumor marker sialyl-Lewis a levels
    • Orntoft, T. F., Vestergaard, E. M., Holmes, E., Jakobsen, J. S. et al., Influence of Lewis alpha1-3/4-L-fucosyltransferase (FUT3) gene mutations on enzyme activity, erythrocyte phenotyping, and circulating tumor marker sialyl-Lewis a levels. J. Biol. Chem. 1996, 271, 32260-32268.
    • (1996) J. Biol. Chem. , vol.271 , pp. 32260-32268
    • Orntoft, T.F.1    Vestergaard, E.M.2    Holmes, E.3    Jakobsen, J.S.4
  • 29
    • 18844468498 scopus 로고    scopus 로고
    • Lewis and secretor gene dosages affect CA19-9 and DU-PAN-2 serum levels in normal individuals and colorectal cancer patients
    • Narimatsu, H., Iwasaki, H., Nakayama, F., Ikehara, Y. et al., Lewis and secretor gene dosages affect CA19-9 and DU-PAN-2 serum levels in normal individuals and colorectal cancer patients. Cancer Res. 1998, 58, 512-518.
    • (1998) Cancer Res. , vol.58 , pp. 512-518
    • Narimatsu, H.1    Iwasaki, H.2    Nakayama, F.3    Ikehara, Y.4
  • 30
    • 0026003124 scopus 로고
    • Elevated serum levels of Dupan-2 in pancreatic cancer patients negative for Lewis blood group phenotype
    • Kawa, S., Oguchi, H., Kobayashi, T., Tokoo, M. et al., Elevated serum levels of Dupan-2 in pancreatic cancer patients negative for Lewis blood group phenotype. Br. J. Cancer 1991, 64, 899-902.
    • (1991) Br. J. Cancer , vol.64 , pp. 899-902
    • Kawa, S.1    Oguchi, H.2    Kobayashi, T.3    Tokoo, M.4
  • 31
    • 0023902145 scopus 로고
    • Correlative study on expression of CA 19-9 and DU-PAN-2 in tumor tissue and in serum of pancreatic cancer patients
    • Takasaki, H., Uchida, E., Tempero, M. A., Burnett, D. A. et al., Correlative study on expression of CA 19-9 and DU-PAN-2 in tumor tissue and in serum of pancreatic cancer patients. Cancer Res. 1988, 48, 1435-1438.
    • (1988) Cancer Res. , vol.48 , pp. 1435-1438
    • Takasaki, H.1    Uchida, E.2    Tempero, M.A.3    Burnett, D.A.4
  • 32
    • 84860239658 scopus 로고    scopus 로고
    • Aberrant glycosylation associated with enzymes as cancer biomarkers
    • Meany, D. L., Chan, D. W., Aberrant glycosylation associated with enzymes as cancer biomarkers. Clin Proteomics 2011, 8, 7.
    • (2011) Clin Proteomics , vol.8 , pp. 7
    • Meany, D.L.1    Chan, D.W.2
  • 33
    • 0025262435 scopus 로고
    • Ductal cancers of the pancreas frequently express markers of gastrointestinal epithelial cells
    • Sessa, F., Bonato, M., Frigerio, B., Capella, C. et al., Ductal cancers of the pancreas frequently express markers of gastrointestinal epithelial cells. Gastroenterology 1990, 98, 1655-1665.
    • (1990) Gastroenterology , vol.98 , pp. 1655-1665
    • Sessa, F.1    Bonato, M.2    Frigerio, B.3    Capella, C.4
  • 34
    • 0034844959 scopus 로고    scopus 로고
    • N-Glycolylneuraminic acid in human tumours
    • Malykh, Y. N., Schauer, R., Shaw, L., N-Glycolylneuraminic acid in human tumours. Biochimie 2001, 83, 623-634.
    • (2001) Biochimie , vol.83 , pp. 623-634
    • Malykh, Y.N.1    Schauer, R.2    Shaw, L.3
  • 35
    • 0025270738 scopus 로고
    • Molecular genetic basis of the histo-blood group ABO system
    • Yamamoto, F., Clausen, H., White, T., Marken, J. et al., Molecular genetic basis of the histo-blood group ABO system. Nature 1990, 345, 229-233.
    • (1990) Nature , vol.345 , pp. 229-233
    • Yamamoto, F.1    Clausen, H.2    White, T.3    Marken, J.4
  • 36
    • 0030868965 scopus 로고    scopus 로고
    • Significance of individual point mutations, T202C and C314T, in the human Lewis (FUT3) gene for expression of Lewis antigens by the human alpha(1,3/1,4)-fucosyltransferase, Fuc-TIII
    • Elmgren, A., Mollicone, R., Costache, M., Borjeson, C. et al., Significance of individual point mutations, T202C and C314T, in the human Lewis (FUT3) gene for expression of Lewis antigens by the human alpha(1, 3/1, 4)-fucosyltransferase, Fuc-TIII. J. Biol. Chem. 1997, 272, 21994-21998.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21994-21998
    • Elmgren, A.1    Mollicone, R.2    Costache, M.3    Borjeson, C.4
  • 37
    • 33749145859 scopus 로고    scopus 로고
    • Multilectin affinity chromatography for characterization of multiple glycoprotein biomarker candidates in serum from breast cancer patients
    • Yang, Z., Harris, L. E., Palmer-Toy, D. E., Hancock, W. S., Multilectin affinity chromatography for characterization of multiple glycoprotein biomarker candidates in serum from breast cancer patients. Clin. Chem. 2006, 52, 1897-1905.
    • (2006) Clin. Chem. , vol.52 , pp. 1897-1905
    • Yang, Z.1    Harris, L.E.2    Palmer-Toy, D.E.3    Hancock, W.S.4
  • 38
    • 78650870657 scopus 로고    scopus 로고
    • Shotgun glycomics: a microarray strategy for functional glycomics
    • Song, X., Lasanajak, Y., Xia, B., Heimburg-Molinaro, J. et al., Shotgun glycomics: a microarray strategy for functional glycomics. Nat. Methods 2011, 8, 85-90.
    • (2011) Nat. Methods , vol.8 , pp. 85-90
    • Song, X.1    Lasanajak, Y.2    Xia, B.3    Heimburg-Molinaro, J.4
  • 39
    • 33947581026 scopus 로고    scopus 로고
    • N-linked glycosylation profiling of pancreatic cancer serum using capillary liquid phase separation coupled with mass spectrometric analysis
    • Zhao, J., Qiu, W., Simeone, D. M., Lubman, D. M., N-linked glycosylation profiling of pancreatic cancer serum using capillary liquid phase separation coupled with mass spectrometric analysis. J. Proteome Res. 2007, 6, 1126-1138.
    • (2007) J. Proteome Res. , vol.6 , pp. 1126-1138
    • Zhao, J.1    Qiu, W.2    Simeone, D.M.3    Lubman, D.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.