Handling of baseline measurements in the analysis of crossover trials

Statistics in Medicine

Volumn 31, Issue 17, 2012, Pages 1791-1803

  Chen, Xun ^a   Meng, Zhaoling ^a   Zhang, Ji ^a  

^a SANOFI   (France)

Author keywords

Between period correlation; Carryover effect; Joint modeling; Within period correlation

Indexed keywords

ANALYSIS OF VARIANCE; ANALYTIC METHOD; ARTICLE; COMPARATIVE STUDY; CORRELATION ANALYSIS; CROSSOVER PROCEDURE; JOINT MODELING METHOD; MEASUREMENT ERROR; STATISTICAL ANALYSIS; STIMULATION;

CLINICAL TRIALS AS TOPIC; COMPUTER SIMULATION; CROSS-OVER STUDIES; DATA INTERPRETATION, STATISTICAL; ELECTROCARDIOGRAPHY; HUMANS; MODELS, STATISTICAL;

EID: 84864003135     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.4466     Document Type: Article

References (10)

1. Follmann DA. The Effects of Screening on Some Pretest-Posttest Variance. Biometrics 1991; 47:763-771.
2. Laird N. Further Comparative Analysis of Pretest-Posttest Research Designs. The American Statistician 1983; 37:329-340.
3. Senn S. Testing for Baseline Balance in Clinical Trials. Statistics in Medicine 1994; 13:1715-1726.
4. Jones B, Kenward MG. Design and Analysis of Cross-over Trials, 2nd ed. Chapman and Hall: London, 2002.
5. Ratkowsky DA, Evans MA, Alldredge JR. Crossover Experiments. Marcel Dekker, Inc.: New York, 1993.
6. Senn S. Cross-over trials in clinical research, 2nd ed. John Wiley & Sons: New York City, 2002.
7. TM, Version 8.2, SAS Inst. Inc., Cary, NC, 2000.
8. Kenward M, Roger J. Small Sample Inference for Fixed Effects from Restricted Maximum Likelihood. Biometrics 1997; 53:983-997.
9. Chen X, Wei L. A comparison of ANOVA method and mixed model approach in the analysis of early phase crossover studies. Statistics in Medicine 2003; 22:2821-2833.
10. Chen X. The adjustment of random baseline measurements in treatment effect estimation. Journal of Statistical Planning and Inference 2006; 136:4161-4175.