Regulation of inflammatory chemokine receptors on blood T cells associated to the circulating versus liver chemokines in dengue fever

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  de Oliveira Pint, Luzia Maria ^a   Marinho, Cíntia Ferreira ^a   Povoa, Tiago Fajardo ^a   de Azeredo, Elzinandes Leal ^a   de Souza, Luiza Assed ^b   Barbosa, Luiza Damian Ribeiro ^b   Motta Castro, Ana Rita C ^c   Alves, Ada M B ^a   Ávila, Carlos André Lins ^d   de Souza, Luiz José ^b   da Cunha, Rivaldo Venâncio ^c   Damasco, Paulo Vieira ^d   Paes, Marciano Viana ^a   Kubelka, Claire Fernandes ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b Centro Regional de Referência em Dengue Campos dos Goytacazes   (Brazil)

^c FEDERAL UNIVERSITY OF MATO GROSSO DO SUL   (Brazil)

^d HOSPITAL UNIVERSITÁRIO PEDRO ERNESTO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR3; HERMES ANTIGEN; INTERLEUKIN 7 RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES;

ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COUNT; CELL MIGRATION; CONTROLLED STUDY; CYTOTOXICITY; DENGUE; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; LIVER; MAJOR CLINICAL STUDY; MALE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TH1 CELL; THROMBOCYTE; UPREGULATION;

ADULT; BIOLOGICAL MARKERS; BLOOD PLATELETS; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHEMOKINES; DENGUE; FEMALE; HUMANS; INFLAMMATION; LIGANDS; LIVER; MALE; RECEPTORS, CHEMOKINE; UP-REGULATION;

EID: 84863991801     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038527     Document Type: Article

References (70)

1. Whitehorn J, Simmons CP, (2011) The pathogenesis of dengue. Vaccine.
2. Sabin AB, (1952) Research on dengue during World War II. Am J Trop Med Hyg 1: 30-50.
3. Murphy BR, Whitehead SS, (2011) Immune response to dengue virus and prospects for a vaccine. Annu Rev Immunol 29: 587-619.
4. Kliks SC, Nisalak A, Brandt WE, Wahl L, Burke DS, (1989) Antibody-dependent enhancement of dengue virus growth in human monocytes as a risk factor for dengue hemorrhagic fever. Am J Trop Med Hyg 40: 444-451.
5. Mongkolsapaya J, Dejnirattisai W, Xu XN, Vasanawathana S, Tangthawornchaikul N, et al. (2003) Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat Med 9: 921-927.
6. Mongkolsapaya J, Duangchinda T, Dejnirattisai W, Vasanawathana S, Avirutnan P, et al. (2006) T cell responses in dengue hemorrhagic fever: are cross-reactive T cells suboptimal? J Immunol 176: 3821-3829.
7. Mangada MM, Rothman AL, (2005) Altered cytokine responses of dengue-specific CD4+ T cells to heterologous serotypes. J Immunol 175: 2676-2683.
8. Dong T, Moran E, Vinh Chau N, Simmons C, Luhn K, et al. (2007) High pro-inflammatory cytokine secretion and loss of high avidity cross-reactive cytotoxic T-cells during the course of secondary dengue virus infection. PLoS ONE 2: e1192.
9. Srikiatkhachorn A, Green S, (2010) Markers of dengue disease severity. Curr Top Microbiol Immunol 338: 67-82.
10. Simmons CP, Dong T, Chau NV, Dung NT, Chau TN, et al. (2005) Early T-cell responses to dengue virus epitopes in Vietnamese adults with secondary dengue virus infections. J Virol 79: 5665-5675.
11. Heydtmann M, Adams DH, (2002) Understanding selective trafficking of lymphocyte subsets. Gut 50: 150-152.
12. Rot A, von Andrian UH, (2004) Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells. Annu Rev Immunol 22: 891-928.
13. von Andrian UH, Mackay CR, (2000) T-cell function and migration. Two sides of the same coin. N Engl J Med 343: 1020-1034.
14. Salgame P, Abrams JS, Clayberger C, Goldstein H, Convit J, et al. (1991) Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones. Science 254: 279-282.
15. Paliard X, de Waal Malefijt R, Yssel H, Blanchard D, Chretien I, et al. (1988) Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones. J Immunol 141: 849-855.
16. Romagnani S, (2000) T-cell subsets (Th1 versus Th2). Ann Allergy Asthma Immunol 85: 9-18; quiz 18, 21.
17. Maggi E, Manetti R, Annunziato F, Cosmi L, Giudizi MG, et al. (1997) Functional characterization and modulation of cytokine production by CD8+ T cells from human immunodeficiency virus-infected individuals. Blood 89: 3672-3681.
18. Gulzar N, Diker B, Balasubramanian S, Jiang JQ, Copeland KF, (2011) Human immunodeficiency virus-1 infection protects against a Tc1-to-Tc2 shift in CD8(+) T cells. Hum Immunol.
19. Kim CH, Rott L, Kunkel EJ, Genovese MC, Andrew DP, et al. (2001) Rules of chemokine receptor association with T cell polarization in vivo. J Clin Invest 108: 1331-1339.
20. Tomiyama H, Takata H, Matsuda T, Takiguchi M, (2004) Phenotypic classification of human CD8+ T cells reflecting their function: inverse correlation between quantitative expression of CD27 and cytotoxic effector function. Eur J Immunol 34: 999-1010.
21. Kobayashi N, Kondo T, Takata H, Yokota S, Takiguchi M, (2006) Functional and phenotypic analysis of human memory CD8+ T cells expressing CXCR3. J Leukoc Biol 80: 320-329.
22. Rabin RL, Park MK, Liao F, Swofford R, Stephany D, et al. (1999) Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling. J Immunol 162: 3840-3850.
23. Rabin RL, Alston MA, Sircus JC, Knollmann-Ritschel B, Moratz C, et al. (2003) CXCR3 is induced early on the pathway of CD4+ T cell differentiation and bridges central and peripheral functions. J Immunol 171: 2812-2824.
24. Imai T, Nagira M, Takagi S, Kakizaki M, Nishimura M, et al. (1999) Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine. Int Immunol 11: 81-88.
25. Kondo T, Takiguchi M, (2009) Human memory CCR4+CD8+ T cell subset has the ability to produce multiple cytokines. Int Immunol 21: 523-532.
26. Lee YR, Liu MT, Lei HY, Liu CC, Wu JM, et al. (2006) MCP-1, a highly expressed chemokine in dengue haemorrhagic fever/dengue shock syndrome patients, may cause permeability change, possibly through reduced tight junctions of vascular endothelium cells. J Gen Virol 87: 3623-3630.
27. Nightingale ZD, Patkar C, Rothman AL, (2008) Viral replication and paracrine effects result in distinct, functional responses of dendritic cells following infection with dengue 2 virus. J Leukoc Biol 84: 1028-1038.
28. Gandini M, Reis SR, Torrentes-Carvalho A, Azeredo EL, Freire Mda S, et al. (2011) Dengue-2 and yellow fever 17DD viruses infect human dendritic cells, resulting in an induction of activation markers, cytokines and chemokines and secretion of different TNF-alpha and IFN-alpha profiles. Mem Inst Oswaldo Cruz 106: 594-605.
29. Avirutnan P, Malasit P, Seliger B, Bhakdi S, Husmann M, (1998) Dengue virus infection of human endothelial cells leads to chemokine production, complement activation, and apoptosis. J Immunol 161: 6338-6346.
30. Huang YH, Lei HY, Liu HS, Lin YS, Liu CC, et al. (2000) Dengue virus infects human endothelial cells and induces IL-6 and IL-8 production. Am J Trop Med Hyg 63: 71-75.
31. Talavera D, Castillo AM, Dominguez MC, Gutierrez AE, Meza I, (2004) IL8 release, tight junction and cytoskeleton dynamic reorganization conducive to permeability increase are induced by dengue virus infection of microvascular endothelial monolayers. J Gen Virol 85: 1801-1813.
32. Dejnirattisai W, Duangchinda T, Lin CL, Vasanawathana S, Jones M, et al. (2008) A complex interplay among virus, dendritic cells, T cells, and cytokines in dengue virus infections. J Immunol 181: 5865-5874.
33. Chau TN, Quyen NT, Thuy TT, Tuan NM, Hoang DM, et al. (2008) Dengue in Vietnamese infants-results of infection-enhancement assays correlate with age-related disease epidemiology, and cellular immune responses correlate with disease severity. J Infect Dis 198: 516-524.
34. Aplin AE, Howe A, Alahari SK, Juliano RL, (1998) Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins. Pharmacol Rev 50: 197-263.
35. Harris ES, McIntyre TM, Prescott SM, Zimmerman GA, (2000) The leukocyte integrins. J Biol Chem 275: 23409-23412.
36. Springer TA, (1990) Adhesion receptors of the immune system. Nature 346: 425-434.
37. Hynes RO, (1992) Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69: 11-25.
38. Pribila JT, Quale AC, Mueller KL, Shimizu Y, (2004) Integrins and T cell-mediated immunity. Annu Rev Immunol 22: 157-180.
39. Wagner C, Hansch GM, Stegmaier S, Denefleh B, Hug F, et al. (2001) The complement receptor 3, CR3 (CD11b/CD18), on T lymphocytes: activation-dependent up-regulation and regulatory function. Eur J Immunol 31: 1173-1180.
40. Drillenburg P, Pals ST, (2000) Cell adhesion receptors in lymphoma dissemination. Blood 95: 1900-1910.
41. Mohamadzadeh M, DeGrendele H, Arizpe H, Estess P, Siegelman M, (1998) Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA-dependent primary adhesion. J Clin Invest 101: 97-108.
42. Kaech SM, Tan JT, Wherry EJ, Konieczny BT, Surh CD, et al. (2003) Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol 4: 1191-1198.
43. Barniol J, Gaczkowski R, Barbato EV, da Cunha RV, Salgado D, et al. (2011) Usefulness and applicability of the revised dengue case classification by disease: multi-centre study in 18 countries. BMC Infect Dis 11: 106.
44. Chen RF, Yang KD, Wang L, Liu JW, Chiu CC, et al. (2007) Different clinical and laboratory manifestations between dengue haemorrhagic fever and dengue fever with bleeding tendency. Trans R Soc Trop Med Hyg 101: 1106-1113.
45. Kadhiravan T, Saxena A, Singh A, Broor S, Sharma SK, et al. (2010) Association of Intracellular T(H)1-T(H)2 Balance in CD4+ T-cells and MIP-1alpha in CD8+ T-cells with Disease Severity in Adults with Dengue. Immune Netw 10: 164-172.
46. Karpus WJ, Lukacs NW, Kennedy KJ, Smith WS, Hurst SD, et al. (1997) Differential CC chemokine-induced enhancement of T helper cell cytokine production. J Immunol 158: 4129-4136.
47. Daucher M, Price DA, Brenchley JM, Lamoreaux L, Metcalf JA, et al. (2008) Virological outcome after structured interruption of antiretroviral therapy for human immunodeficiency virus infection is associated with the functional profile of virus-specific CD8+ T cells. J Virol 82: 4102-4114.
48. Almeida JR, Price DA, Papagno L, Arkoub ZA, Sauce D, et al. (2007) Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover. J Exp Med 204: 2473-2485.
49. Seder RA, Darrah PA, Roederer M, (2008) T-cell quality in memory and protection: implications for vaccine design. Nat Rev Immunol 8: 247-258.
50. Khanna R, Burrows SR, Thomson SA, Moss DJ, Cresswell P, et al. (1997) Class I processing-defective Burkitt's lymphoma cells are recognized efficiently by CD4+ EBV-specific CTLs. J Immunol 158: 3619-3625.
51. Casazza JP, Betts MR, Price DA, Precopio ML, Ruff LE, et al. (2006) Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation. J Exp Med 203: 2865-2877.
52. Zhou W, Sharma M, Martinez J, Srivastava T, Diamond DJ, et al. (2007) Functional characterization of BK virus-specific CD4+ T cells with cytotoxic potential in seropositive adults. Viral Immunol 20: 379-388.
53. Duangchinda T, Dejnirattisai W, Vasanawathana S, Limpitikul W, Tangthawornchaikul N, et al. (2010) Immunodominant T-cell responses to dengue virus NS3 are associated with DHF. Proc Natl Acad Sci U S A 107: 16922-16927.
54. Betts MR, Brenchley JM, Price DA, De Rosa SC, Douek DC, et al. (2003) Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. J Immunol Methods 281: 65-78.
55. Loetscher M, Gerber B, Loetscher P, Jones SA, Piali L, et al. (1996) Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med 184: 963-969.
56. Farber JM, (1997) Mig and IP-10: CXC chemokines that target lymphocytes. J Leukoc Biol 61: 246-257.
57. Gao P, Zhou XY, Yashiro-Ohtani Y, Yang YF, Sugimoto N, et al. (2003) The unique target specificity of a nonpeptide chemokine receptor antagonist: selective blockade of two Th1 chemokine receptors CCR5 and CXCR3. J Leukoc Biol 73: 273-280.
58. Arai K, Liu ZX, Lane T, Dennert G, (2002) IP-10 and Mig facilitate accumulation of T cells in the virus-infected liver. Cell Immunol 219: 48-56.
59. Apolinario A, Majano PL, Alvarez-Perez E, Saez A, Lozano C, et al. (2002) Increased expression of T cell chemokines and their receptors in chronic hepatitis C: relationship with the histological activity of liver disease. Am J Gastroenterol 97: 2861-2870.
60. Larrubia JR, Calvino M, Benito S, Sanz-de-Villalobos E, Perna C, et al. (2007) The role of CCR5/CXCR3 expressing CD8+ cells in liver damage and viral control during persistent hepatitis C virus infection. J Hepatol 47: 632-641.
61. Araujo LM, Lefort J, Nahori MA, Diem S, Zhu R, et al. (2004) Exacerbated Th2-mediated airway inflammation and hyperresponsiveness in autoimmune diabetes-prone NOD mice: a critical role for CD1d-dependent NKT cells. Eur J Immunol 34: 327-335.
62. Ip PP, Liao F, (2010) Resistance to dengue virus infection in mice is potentiated by CXCL10 and is independent of CXCL10-mediated leukocyte recruitment. J Immunol 184: 5705-5714.
63. Ahamed J, Belting M, Ruf W, (2005) Regulation of tissue factor-induced signaling by endogenous and recombinant tissue factor pathway inhibitor 1. Blood 105: 2384-2391.
64. Campbell JJ, Haraldsen G, Pan J, Rottman J, Qin S, et al. (1999) The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells. Nature 400: 776-780.
65. Seneviratne SL, Black AP, Jones L, Bailey AS, Ogg GS, (2007) The role of skin-homing T cells in extrinsic atopic dermatitis. QJM 100: 19-27.
66. Guabiraba R, Marques RE, Besnard AG, Fagundes CT, Souza DG, et al. (2010) Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice. PLoS One 5: e15680.
67. Azeredo EL, Zagne SM, Alvarenga AR, Nogueira RM, Kubelka CF, et al. (2006) Activated peripheral lymphocytes with increased expression of cell adhesion molecules and cytotoxic markers are associated with dengue fever disease. Mem Inst Oswaldo Cruz 101: 437-449.
68. Schluns KS, Stoklasek T, Lefrancois L, (2005) The roles of interleukin-15 receptor alpha: trans-presentation, receptor component, or both? Int J Biochem Cell Biol 37: 1567-1571.
69. Huster KM, Busch V, Schiemann M, Linkemann K, Kerksiek KM, et al. (2004) Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets. Proc Natl Acad Sci U S A 101: 5610-5615.
70. Bozza FA, Cruz OG, Zagne SM, Azeredo EL, Nogueira RM, et al. (2008) Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity. BMC Infect Dis 8: 86.