Direct and simultaneous determination of 5-aminolaevulinic acid and porphobilinogen in urine by hydrophilic interaction liquid chromatography-electrospray ionisation/tandem mass spectrometry

Biomedical Chromatography

Volumn 26, Issue 8, 2012, Pages 1033-1040

  Benton, Christopher M ^a,b   Couchman, Lewis ^a   Marsden, Joanne T ^a   Rees, David C ^a   Moniz, Caje ^a   Lim, Chang Kee ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

5 aminolaevulinic acid; Acute hepatic porphyrias; Electrospray ionisation tandem mass spectrometry; HILIC; Porphobilinogen

Indexed keywords

BODY FLUIDS; CORRELATION METHODS; DIAGNOSIS; DRUG PRODUCTS; ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PATIENT TREATMENT; SCREENING; SPECTROPHOTOMETERS; SPECTROPHOTOMETRY;

5-AMINOLAEVULINIC ACID; 5-AMINOLEVULINIC ACID; ACUTE HEPATIC PORPHYRIA; ANALYTES; ELECTROSPRAY IONIZATION TANDEM MASS SPECTROMETRY; HEPATIC PORPHYRIA; HILIC; HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHIES; PORPHOBILINOGEN; URINE SAMPLE;

HYDROPHILICITY;

ACETONITRILE; AMINOLEVULINIC ACID; PORPHOBILINOGEN;

ACCURACY; AMINO ACID URINE LEVEL; ANALYTIC METHOD; ARTICLE; CALIBRATION; CENTRIFUGATION; CLINICAL ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; CORRELATION COEFFICIENT; DERIVATIZATION; DILUTION; ELECTROSPRAY MASS SPECTROMETRY; HEPATIC PORPHYRIA; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; PATIENT MONITORING; QUANTITATIVE ASSAY; REPRODUCIBILITY; SCREENING TEST; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY; URINALYSIS; URINE LEVEL;

EID: 84863990898     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2770     Document Type: Article

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