Plasma cytokines, glomerular filtration rate and adipose tissue cytokines gene expression in chronic kidney disease (CKD) patients

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 22, Issue 11, 2012, Pages 981-988

  Spoto, B ^a   Leonardis, D ^a   Parlongo, R M ^a   Pizzini, P ^a   Pisano, A ^a   Cutrupi, S ^a   Testa, A ^a   Tripepi, G ^a   Zoccali, C ^a   Mallamaci, F ^a  

^a CNR   (Italy)

Author keywords

Adipose tissue; Chronic kidney disease; Cytokines; Gene expression

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ADIPOSE TISSUE; ADULT; AGED; ARTICLE; BLOOD; CASE CONTROL STUDY; CHRONIC KIDNEY FAILURE; FEMALE; GENE EXPRESSION; GENETICS; GLOMERULUS FILTRATION RATE; HUMAN; MALE; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; STATISTICAL MODEL;

ADIPOSE TISSUE; ADULT; AGED; CASE-CONTROL STUDIES; FEMALE; GENE EXPRESSION; GLOMERULAR FILTRATION RATE; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; LINEAR MODELS; MALE; MIDDLE AGED; RENAL INSUFFICIENCY, CHRONIC; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84863990722     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2011.01.005     Document Type: Article

References (27)

1. Sarnak M.J., Levey A.S., Schoolwerth A.C., Coresh J., Culleton B., Hamm L.L., et al. American heart association councils on kidney in cardiovascular disease, high blood pressure research, clinical cardiology, and epidemiology and prevention. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American heart association councils on kidney in cardiovascular disease, high blood pressure research, clinical cardiology, and epidemiology and prevention. Circulation 2003, 108:2154-2169.
2. Schiffrin E.L., Lipman M.L., Mann J. Chronic kidney disease: effects on the cardiovascular system. Circulation 2007, 116:85-97.
3. Stinghen A.E., Bucharles S., Riella M.C., Pecoits-Filho R. Immune mechanisms involved in cardiovascular complications of chronic kidney disease. Blood Purif 2010, 29:114-120.
4. Kendrick J., Chonchol M.B. Nontraditional risk factors for cardiovascular disease in patients with chronic kidney disease. Nat Clin Pract Nephrol 2008, 4:672-681.
5. Zoccali C. Traditional and emerging cardiovascular and renal risk factors: an epidemiologic perspective. Kidney Int 2006, 70:26-33.
6. Vidt D.G. Inflammation in renal disease. Am J Cardiol 2006, 97:20A-27A.
7. Stenvinkel P. New insights on inflammation in chronic kidney disease-genetic and non-genetic factors. Nephrol Ther 2006, 2:111-119.
8. Ross W.R., McGill J.B. Epidemiology of obesity and chronic kidney disease. Adv Chronic Kidney Dis 2006, 13:325-335.
9. Mafra D., Guebre-Egziabher F., Fouque D. Body mass index, muscle and fat in chronic kidney disease: questions about survival. Nephrol Dial Transplant 2008, 23:2461-2466.
10. Stenvinkel P., Ketteler M., Johnson R.J., Lindholm B., Pecoits-Filho R., Riella M., et al. IL-10, IL-6, and TNF-alpha: Central factors in the altered cytokine network of uremia - the good, the bad, and the ugly. Kidney Int 2005, 67:1216-1233.
11. Young J.A., Hwang S.J., Sarnak M.J., Hoffmann U., Massaro J.M., Levy D., et al. Association of visceral and subcutaneous adiposity with kidney function. Clin J Am Soc Nephrol 2008, 3:1786-1791.
12. Wellen K.E., Hotamisligil G.S. Obesity-induced inflammatory changes in adipose tissue. J Clin Invest 2003, 112:1785-1788.
13. Bastard J.P., Jardel C., Delattre J., Hainque B., Bruckert E., Oberlin F. Evidence for a link between adipose tissue interleukin-6 content and serum C-reactive protein concentrations in obese subjects. Circulation 1999, 99:2221-2222.
14. Maachi M., Pieroni L., Bruckert E., Jardel C., Fellahi S., Hainque B., et al. Systemic low grade inflammation is related to both circulating and adipose tissue TNFα, leptin and interleukin-6 levels in obese women. Int J Obes 2004, 28:993-997.
15. Clement K., Viguerie N., Poitou C., Carette C., Pelloux V., Curat C.A., et al. Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects. FASEB J 2004, 18:1657-1669.
16. Selvin E., Paynter N.P., Erlinger T.P. The effect of weight loss on C-reactive protein. A systematic review. Arch Intern Med 2007, 167:31-39.
17. Roubicek T., Bartlova M., Krajickova J., Haluzikova D., Mraz M., Lacinova Z., et al. Increased production of proinflammatory cytokines in adipose tissue of patients with end-stage renal disease. Nutrition 2009, 25:762-768.
18. Levey A.S., Greene T., Kusek J.W., Beck G.L. Modification of Diet in Renal Disease (MDRD) study group. A simplified equation to predict glomerular filtration rate from serum creatinine (abstract). J Am Soc Nephrol 2000, 11:155A.
19. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
20. Jager K.J., Zoccali C., Macleod A., Dekker F.W. Confounding: what it is and how to deal with it. Kidney Int 2008, 73:256-260.
21. Zoccali C., Postorino M., Martorano C., Salnitro F., Maggiore Q. The 'breakpoint' test, a new statistical method for studying progression of chronic renal failure. Nephrol Dial Transplant 1989, 4:101-104.
22. Descamps-Latscha B., Herbelin A., Nguyen A.T., Roux-Lombard P., Zingraff J., Moynot A., et al. Balance between IL-1 beta, TNF-alpha, and their specific inhibitors in chronic renal failure and maintenance dialysis. Relationships with activation markers of T cells, B cells, and monocyte. J Immunol 1995, 154:882-892.
23. Barreto D.V., Barreto F.C., Liabeuf S., Temmar M., Lemke H.D., Tribouilloy C., et al. European Uremic Toxin work group (EUTox). Plasma interleukin-6 is independently associated with mortality in both hemodialysis and pre-dialysis patients with chronic kidney disease. Kidney Int 2010, 77:550-556.
24. Bemelmans M.H., Gouma D.J., Buurman W.A. Influence of nephrectomy on tumor necrosis factor clearance in a murine model. J Immunol 1993, 150:2007-2017.
25. Bemelmans M.H., van Tits L.J., Buurman W.A. Tumor necrosis factor: function, release and clearance. Crit Rev Immunol 1996, 16:1-11.
26. Wajchenberg B.L. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev 2000, 21:697-738.
27. Dolinkova M., Dostalova I., Lacinova Z., Michalsky D., Haluzikova D., Mraz M., et al. The endocrine profile of subcutaneous and visceral adipose tissue of obese patients. Mol Cell Endocrinol 2008, 291:63-70.