Immediate vs. delayed treatment in patients with acute hepatitis C based on IL28B polymorphism: A model-based analysis

Journal of Hepatology

Volumn 57, Issue 2, 2012, Pages 260-266

  Deuffic Burban, Sylvie ^a,b   Castel, Hélène ^c,d,e   Wiegand, Johannes ^f,g   Manns, Michael P ^f   Wedemeyer, Heiner ^f   Mathurin, Philippe ^c,h   Yazdanpanah, Yazdan ^a,b,d,i,j  

^a INSERM   (France)

^b UNIV LILLE   (France)

^c LILLE UNIVERSITY HOSPITAL   (France)

^d Service Universitaire des Maladies Infectieuses et du Voyageur   (France)

^e UNIVERSITY OF MONTREAL   (Canada)

^f HANNOVER MEDICAL SCHOOL   (Germany)

^g UNIVERSITY OF LEIPZIG   (Germany)

^h UNIVERSITÉ DE LILLE   (France)

ⁱ UNIVERSITÉ PARIS DESCARTES   (France)

^j BICHAT HOSPITAL   (France)

more..

Author keywords

Acute hepatitis C treatment; Chronic hepatitis C; Model based decision analysis; Optimal timing; Sustained virological response

Indexed keywords

INTERLEUKIN 28B;

ACUTE HEPATITIS; ANTIVIRAL THERAPY; ARTICLE; CHRONIC HEPATITIS; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE COURSE; DISEASE TRANSMISSION; DNA POLYMORPHISM; EARLY INTERVENTION; GENOTYPE; HEALTH CARE PERSONNEL; HEPATITIS C; HEPATITIS C VIRUS; PRIORITY JOURNAL; PROBABILITY; STATISTICAL MODEL; THERAPY DELAY; TREATMENT RESPONSE; VIRAL CLEARANCE;

ACUTE DISEASE; ANTIVIRAL AGENTS; GENOTYPE; HEPATITIS C; HUMANS; INTERLEUKINS; POLYMORPHISM, GENETIC; RNA, VIRAL;

EID: 84863988435     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.03.020     Document Type: Article

References (47)

1. J.T. Blackard, M.T. Shata, N.J. Shire, and K.E. Sherman Acute hepatitis C virus infection: a chronic problem Hepatology 47 2008 321 331
2. J.M. Micallef, J.M. Kaldor, and G.J. Dore Spontaneous viral clearance following acute hepatitis C infection: a systematic review of longitudinal studies J Viral Hepat 13 2006 34 41
3. T. Santantonio, and M. Fasano Therapy of acute hepatitis C: a review of literature Curr Pharm Des 14 2008 1686 1689
4. T. Santantonio, J. Wiegand, and J.T. Gerlach Acute hepatitis C: current status and remaining challenges J Hepatol 49 2008 625 633
5. J. Wiegand, K. Deterding, M. Cornberg, and H. Wedemeyer Treatment of acute hepatitis C: the success of monotherapy with (pegylated) interferon alpha J Antimicrob Chemother 62 2008 860 865
6. K.E. Corey, J. Mendez-Navarro, E.C. Gorospe, H. Zheng, and R.T. Chung Early treatment improves outcomes in acute hepatitis C virus infection: a meta-analysis J Viral Hepat 17 2010 201 207
7. R.T. Chung Acute hepatitis C virus infection Clin Infect Dis 41 2005 S14 S17
8. J. Delwaide, N. Bourgeois, C. Gerard, S. De Maeght, F. Mokaddem, and E. Wain Treatment of acute hepatitis C with interferon alpha-2b: early initiation of treatment is the most effective predictive factor of sustained viral response Aliment Pharmacol Ther 20 2004 15 22
9. H. Hofer, T. Watkins-Riedel, O. Janata, E. Penner, H. Holzmann, and P. Steindl-Munda Spontaneous viral clearance in patients with acute hepatitis C can be predicted by repeated measurements of serum viral load Hepatology 37 2003 60 64
10. E. Jaeckel, M. Cornberg, H. Wedemeyer, T. Santantonio, J. Mayer, and M. Zankel Treatment of acute hepatitis C with interferon alfa-2b N Engl J Med 345 2001 1452 1457
11. D.L. Thomas, C.L. Thio, M.P. Martin, Y. Qi, D. Ge, and C. O'Huigin Genetic variation in IL28B and spontaneous clearance of hepatitis C virus Nature 461 2009 798 801
12. S. Knapp, U. Warshow, K.M. Ho, D. Hegazy, A.M. Little, and A. Fowell A polymorphism in IL28B distinguishes exposed, uninfected individuals from spontaneous resolvers of HCV infection Gastroenterology 141 2011 320 325 e321-e322
13. M.A. Montes-Cano, J.R. Garcia-Lozano, C. Abad-Molina, M. Romero-Gomez, N. Barroso, and J. Aguilar-Reina Interleukin-28B genetic variants and hepatitis virus infection by different viral genotypes Hepatology 52 2010 33 37
14. J.R. Orland, T.L. Wright, and S. Cooper Acute hepatitis C Hepatology 33 2001 321 327
15. T. Santantonio, E. Medda, C. Ferrari, P. Fabris, G. Cariti, and M. Massari Risk factors and outcome among a large patient cohort with community-acquired acute hepatitis C in Italy Clin Infect Dis 43 2006 1154 1159
16. M. Wiese, F. Berr, M. Lafrenz, H. Porst, and U. Oesen Low frequency of cirrhosis in a hepatitis C (genotype 1b) single-source outbreak in Germany: a 20-year multicenter study Hepatology 32 2000 91 96
17. S.A. Glynn, D.J. Wright, S.H. Kleinman, D. Hirschkorn, Y. Tu, and C. Heldebrant Dynamics of viremia in early hepatitis C virus infection Transfusion 45 2005 994 1002
18. J.W. Mosley, E.A. Operskalski, L.H. Tobler, W.W. Andrews, B. Phelps, and J. Dockter Viral and host factors in early hepatitis C virus infection Hepatology 42 2005 86 92
19. P. Lampertico, M. Rumi, R. Romeo, A. Craxi, R. Soffredini, and D. Biassoni A multicenter randomized controlled trial of recombinant interferon-alpha2b in patients with acute transfusion-associated hepatitis C Hepatology 19 1994 19 22
20. J. Wiegand, P. Buggisch, W. Boecher, S. Zeuzem, C.M. Gelbmann, and T. Berg Early monotherapy with pegylated interferon alpha-2b for acute hepatitis C infection: the HEP-NET acute-HCV-II study Hepatology 43 2006 250 256
21. J. Grebely, K. Petoumenos, M. Hellard, G.V. Matthews, V. Suppiah, and T. Applegate Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection Hepatology 52 2010 1216 1224
22. C.C. Wang, E. Krantz, J. Klarquist, M. Krows, L. McBride, and E.P. Scott Acute hepatitis C in a contemporary US cohort: modes of acquisition and factors influencing viral clearance J Infect Dis 196 2007 1474 1482
23. S.M. Kamal, A.E. Fouly, R.R. Kamel, B. Hockenjos, A. Al Tawil, and K.E. Khalifa Peginterferon alfa-2b therapy in acute hepatitis C: impact of onset of therapy on sustained virologic response Gastroenterology 130 2006 632 638
24. A.M. Courouce, and J. Pillonel Transfusion-transmitted viral infections. Retrovirus and Viral Hepatitis Working Groups of the French Society of Blood Transfusion N Engl J Med 335 1996 1609 1610
25. A.J. Thompson, A.J. Muir, M.S. Sulkowski, D. Ge, J. Fellay, and K.V. Shianna Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus Gastroenterology 139 2010 120 129 e118
26. M.G. Ghany, D.B. Strader, D.L. Thomas, and L.B. Seeff Diagnosis, management, and treatment of hepatitis C: an update Hepatology 49 2009 1335 1374
27. EASL Clinical Practice Guidelines Management of hepatitis C virus infection J Hepatol 55 2011 245 264
28. P. Sarobe, J.J. Lasarte, N. Garcia, M.P. Civeira, F. Borras-Cuesta, and J. Prieto Characterization of T-cell responses against immunodominant epitopes from hepatitis C virus E2 and NS4a proteins J Viral Hepat 13 2006 47 55
29. G. Badr, N. Bedard, M.S. Abdel-Hakeem, L. Trautmann, B. Willems, and J.P. Villeneuve Early interferon therapy for hepatitis C virus infection rescues polyfunctional, long-lived CD8+ memory T cells J Virol 82 2008 10017 10031
30. N.H. Afdhal The natural history of hepatitis C Semin Liver Dis 24 2004 3 8
31. L. Golden-Mason, J.R. Burton Jr., N. Castelblanco, J. Klarquist, S. Benlloch, and C. Wang Loss of IL-7 receptor alpha-chain (CD127) expression in acute HCV infection associated with viral persistence Hepatology 44 2006 1098 1109
32. W. Kryczka, E. Brojer, D. Zarebska-Michaluk, J. Medynska, and A. Urbaniak Factors influencing natural history of chronic hepatitis C Med Sci Monit 7 2001 212 216
33. P. Farci, A. Shimoda, A. Coiana, G. Diaz, G. Peddis, and J.C. Melpolder The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies Science 288 2000 339 344
34. J.T. Gerlach, H.M. Diepolder, R. Zachoval, N.H. Gruener, M.C. Jung, and A. Ulsenheimer Acute hepatitis C: high rate of both spontaneous and treatment-induced viral clearance Gastroenterology 125 2003 80 88
35. K. Page, J.A. Hahn, J. Evans, S. Shiboski, P. Lum, and E. Delwart Acute hepatitis C virus infection in young adult injection drug users: a prospective study of incident infection, resolution, and reinfection J Infect Dis 200 2009 1216 1226
36. M. Lehmann, M.F. Meyer, M. Monazahian, H.L. Tillmann, M.P. Manns, and H. Wedemeyer High rate of spontaneous clearance of acute hepatitis C virus genotype 3 infection J Med Virol 73 2004 387 391
37. E. Jaeckel, H. Wedemeyer, J. Wiegand, and M.P. Manns Acute hepatitis C virus infection: to treat or not to treat? Gastroenterology 126 2004 1219 1220 author reply 1220
38. A.L. Cox, D.M. Netski, T. Mosbruger, S.G. Sherman, S. Strathdee, and D. Ompad Prospective evaluation of community-acquired acute-phase hepatitis C virus infection Clin Infect Dis 40 2005 951 958
39. M.M. El Gaafary, C. Rekacewicz, A.G. Abdel-Rahman, M.F. Allam, M. El Hosseiny, and M.A. Hamid Surveillance of acute hepatitis C in Cairo, Egypt J Med Virol 76 2005 520 525
40. T. Santantonio, E. Sinisi, A. Guastadisegni, C. Casalino, M. Mazzola, and A. Gentile Natural course of acute hepatitis C: a long-term prospective study Dig Liver Dis 35 2003 104 113
41. L.L. Lewis-Ximenez, G.M. Lauer, J. Schulze Zur Wiesch, P.S. de Sousa, C.F. Ginuino, and G. Paranhos-Baccala Prospective follow-up of patients with acute hepatitis C virus infection in Brazil Clin Infect Dis 50 2010 1222 1230
42. B.H. McGovern, C.E. Birch, M.J. Bowen, L.L. Reyor, E.H. Nagami, and R.T. Chung Improving the diagnosis of acute hepatitis C virus infection with expanded viral load criteria Clin Infect Dis 49 2009 1051 1060
43. M. Vogel, S. Dominguez, S. Bhagani, A. Azwa, E. Page, and M. Guiguet Treatment of acute HCV infection in HIV-positive patients: experience from a multicentre European cohort Antivir Ther 15 2010 267 279
44. L. Piroth, C. Larsen, C. Binquet, L. Alric, I. Auperin, and M.L. Chaix Treatment of acute hepatitis C in human immunodeficiency virus-infected patients: the HEPAIG study Hepatology 52 2010 1915 1921
45. J.E. Arends, S. van Assen, C.J. Stek, A.M. Wensing, J.H. Fransen, and I.M. Schellens Pegylated interferon-alpha monotherapy leads to low response rates in HIV-infected patients with acute hepatitis C Antivir Ther 16 2011 979 988
46. Boesecke C, Stellbrink H-J, Mauss S, Page E, Nelson M, Bhagani S, et al. Does baseline HCV genotype have an impact upon treatment outcome of acute HCV infection in HIV co-infected individuals? In: 18th conference on retroviruses and opportunistic infections, February 27-March 2, 2011, Boston, USA.
47. M. Danta, N. Semmo, P. Fabris, D. Brown, O.G. Pybus, and C.A. Sabin Impact of HIV on host-virus interactions during early hepatitis C virus infection J Infect Dis 197 2008 1558 1566