The PPARc agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and oxidative stress following pilocarpine-induced status epilepticus

Neurological Sciences

Volumn 33, Issue 3, 2012, Pages 559-566

  Hong, Sun ^a   Xin, Yu ^b   HaiQin, Wu ^a   GuiLian, Zhang ^a   Ru, Zhang ^a   ShuQin, Zhan ^a   HuQing, Wang ^a   Li, Yao ^a   Yun, Du ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b 401 Hospital of PLA   (China)

Author keywords

Astrocyte; Cognitive impairment; Epilepsy; GSH; PPAR

Indexed keywords

2 CHLORO 5 NITRO N (4 PYRIDYL)BENZAMIDE; CHLORIDE; GLUTATHIONE; LITHIUM CHLORIDE; PILOCARPINE; ROSIGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; BENZAMIDE DERIVATIVE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE DISULFIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; ASTROCYTOSIS; CELL ACTIVATION; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE MODEL; DRUG MECHANISM; EPILEPTIC STATE; HIPPOCAMPUS; MALE; NERVE CELL INHIBITION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN HOMEOSTASIS; RAT; ANALYSIS OF VARIANCE; ANIMAL; CELL COUNT; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; MAZE TEST; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT; SYSTOLE;

ANALYSIS OF VARIANCE; ANIMALS; ASTROCYTES; BENZAMIDES; CELL COUNT; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE; GLUTATHIONE DISULFIDE; HIPPOCAMPUS; LITHIUM CHLORIDE; MALE; MAZE LEARNING; OXIDATIVE STRESS; PILOCARPINE; PPAR GAMMA; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; STATUS EPILEPTICUS; SYSTOLE; THIAZOLIDINEDIONES;

EID: 84863987276     PISSN: 15901874     EISSN: 15903478     Source Type: Journal    
DOI: 10.1007/s10072-011-0774-2     Document Type: Article

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