Clarifications on oxycodone-naloxone combination in cancer pain management

Supportive Care in Cancer

Volumn 20, Issue 7, 2012, Pages 1351-1352

  Mercadante, Sebastiano ^a  

^a LA MADDALENA CANCER CENTER   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LAXATIVE; NALOXONE; NALOXONE PLUS OXYCODONE; OPIATE; OXYCODONE;

ANALGESIA; CANCER PAIN; CONTROLLED CLINICAL TRIAL (TOPIC); DOSE RESPONSE; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG MEGADOSE; DRUG METABOLISM; GENETIC VARIABILITY; HUMAN; LETTER; PRIORITY JOURNAL; RECOMMENDED DRUG DOSE;

ANALGESICS, OPIOID; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; HUMANS; NALOXONE; NARCOTIC ANTAGONISTS; NEOPLASMS; OXYCODONE; PAIN;

EID: 84863983205     PISSN: 09414355     EISSN: 14337339     Source Type: Journal    
DOI: 10.1007/s00520-012-1449-0     Document Type: Letter

References (6)

1. Mercadante S, Ferrera P, Adile C (2011) High doses of oxycodonenaloxone combination may provide poor analgesia. Support Care Cancer 19:1471-1472
2. Mercadante S (2007) Opioid titration in cancer pain: a critical review. Eur J Pain 11:823-830
3. Mercadante S, Villari P, Ferrera P (2003) A model of acute symptom control unit: Pain Relief and Palliative Care Unit of La Maddalena Cancer Center. Support Care Cancer 11:114-119
4. Mercadante S, Intravaia G, Villari P, Ferrera P, David F, Casuccio A, Mangione S (2008) Clinical and financial analysis of an acute palliative care unit in an oncological department. Palliat Med 22:760-767
5. Mercadante S, Ferrera P, David F, Casuccio A (2011) The use of high doses of oxycodone in an acute palliative care unit. Am J Hosp Palliat Care 28:242-244
6. Ahmedzai S, Nauck F, Bar-Sela G, Bosse B, Leyendecker P, Hopp M (2012) A randomized, double-blind, active-controlled, double-dummy, parallel-group study to determine the safety and efficacy of oxycodone/naloxone prolonged-release tablets in patients with moderate-severe, chronic pain. Palliat Med (in press)