Increased expression of IL-1 receptors in response to IL-1β may produce more IL-6, IL-8, VEGF, and PGE2 in senescent synovial cells induced in vitro than in presenescent cells

Rheumatology International

Volumn 32, Issue 7, 2012, Pages 2005-2010

  Park, Jina ^a   Choi, Hyun Mi ^a   Yang, Hyung In ^a   Yoo, Myung Chul ^a   Kim, Kyoung Soo ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Cyclooxygenase 2 (COX 2); Fibroblast like synoviocytes; Interleukin (IL) 1 receptor; Prostaglandin E2 (PGE2); Senescent synovial cells; Vascular endothelial growth factor (VEGF)

Indexed keywords

BETA GALACTOSIDASE; CYCLOOXYGENASE 2; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1 RECEPTOR TYPE II; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; PROSTAGLANDIN E2; VASCULOTROPIN;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SENESCENCE; SYNOVIOCYTE; WESTERN BLOTTING;

ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; BETA-GALACTOSIDASE; CELL AGING; CELLS, CULTURED; DINOPROSTONE; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; RECEPTORS, INTERLEUKIN-1; SYNOVIAL MEMBRANE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84863981268     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-011-1891-1     Document Type: Article

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