Blocking TNF-α with infliximab alleviates ovariectomy induced mechanical and thermal hyperalgesia in rats

Neurological Sciences

Volumn 33, Issue 3, 2012, Pages 527-533

  Chen, Bai Ling ^a   Li, Yi Qiang ^b   Xie, Deng Hui ^b   He, Qiu Lan ^a   Yang, Xiao Xi ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b Guangzhou Women and Children's Medical Center   (China)

Author keywords

Hyperalgesia; Immunofluorescence; Ovariectomy; Pain behavioral test; Tumor necrosis factor alpha

Indexed keywords

ESTRADIOL; INFLIXIMAB; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DENSITY; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE MODEL; ESTRADIOL BLOOD LEVEL; ESTROGEN DEFICIENCY; FEMALE; HYPERALGESIA; IMMUNOFLUORESCENCE; LUMBAR SPINE; MECHANICAL HYPERALGESIA; MECHANICAL STIMULATION; NONHUMAN; OVARIECTOMY; PAIN ASSESSMENT; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; SPINAL GANGLION; THERMAL HYPERALGESIA; THERMAL STIMULATION;

ABSORPTIOMETRY, PHOTON; ANALYSIS OF VARIANCE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL; BODY WEIGHT; BONE DENSITY; DISEASE MODELS, ANIMAL; ESTRADIOL; FEMALE; GANGLIA, SPINAL; HYPERALGESIA; OVARIECTOMY; PAIN MEASUREMENT; PAIN THRESHOLD; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84863980345     PISSN: 15901874     EISSN: 15903478     Source Type: Journal    
DOI: 10.1007/s10072-011-0743-9     Document Type: Article

References (34)

1. Dawson-Hughes B, National Osteoporosis Foundation Guide Committee (2008) A revised clinician's guide to the prevention and treatment of osteoporosis. J Clin Endocrinol Metab 93(7):2463-2465 (Pubitemid 352008504)
2. Brixen K, Abrahamsen B, Kassem M (2005) Prevention and treatment of osteoporosis in women. Curr Obstet Gynaecol 15(4):251-258 (Pubitemid 41033019)
3. Adera T, Deyo RA, Donatelle RJ (1994) Premature menopause and low back pain. A population-based study. Ann Epidemiol 4:416-422 (Pubitemid 24300246)
4. Hayashi Y (2007) Bone diseases with pain, osteoporosis (in Japanese). Clin Calcium 17(4):606-612
5. Ohtori S, Akazawa T, Murata Y et al (2010) Risedronate decreases bone resorption and improves low back pain in postmenopausal osteoporosis patients without vertebral fractures. J Clin Neurosci 17(2):209-213
6. Iwamoto J, Takeda T, Sato Y, Uzawa M (2005) Comparison of effect of treatment with etidronate and alendronate on lumbar bone mineral density in elderly women with osteoporosis. Yonsei Med J 46(6):750-758 (Pubitemid 43085176)
7. Craft RM (2007) Modulation of pain by estrogens. Pain 132:3-12
8. Mannino CA, South SM, Quinones-Jenab V, Inturrisi CE (2007) Estradiol replacement in ovariectomized rats is antihyperalgesic in the formalin test. J Pain 8(4):334-342 (Pubitemid 46551875)
9. Sarajari S, Oblinger MM (2010) Estrogen effects on pain sensitivity and neuropeptide expression in rat sensory neurons. Exp Neurol 224(1):163-169
10. Bismar H, Diel I, Ziegler R, Pfeilschifter J (1995) Increased cytokine secretion by human bone marrow cells after menopause or discontinuation of estrogen replacement. J Clin Endocrinol Metab 80(11):3351-3355
11. Zheng SX, Vrindts Y, Lopez M et al (1997) Increase in cytokine production (IL-1b, IL-6, TNF-a but not IFN-c, GM-CSF or LIF) by stimulated whole blood cells in postmenopausal osteoporosis. Maturitas 26(1):63-71 (Pubitemid 27063783)
12. Papadaki HA, Tsatsanis C, Christoforidou A et al (2004) Alendronate reduces serum TNF alpha and IL-1beta, increases neutrophil counts, and improves bone mineral density and bone metabolism indices in patients with chronic idiopathic neutropenia (CIN)-associated osteopenia/osteoporosis. J Bone Miner Metab 22(6):577-587 (Pubitemid 39517878)
13. Tsuboi M, Kawakami A, Nakashima T et al (1999) Tumor necrosis factor-alpha and interleukin-1 beta increase the Fas-mediated apoptosis of human osteoblasts. J Lab Clin Med 134(3):222-231 (Pubitemid 29423094)
14. Junger H, Sorkin LS (2000) Nociceptive and inflammatory effects of subcutaneous TNF alpha. Pain 85(1-2):145-151 (Pubitemid 30110754)
15. Xu JT, Xin WJ, Zang Y, Wu CY, Liu XG (2006) The role of tumor necrosis factor alpha in the neuropathic pain induced by Lumbar 5 ventral root transaction in rat. Pain 123:306-321
16. Nicol GD, Lopshire JC, Pafford CM (1997) Tumor necrosis factor enhances the capsaicin sensitivity of rat sensory neurons.J Neurosci 17:975-982 (Pubitemid 27043956)
17. Leung L, Cahill CM (2010) TNF-alpha and neuropathic pain-a review. J Neuroinflammation 7:27
18. Ozaktay AC, Cavanaugh JM, Asik I, DeLeo JA, Weinstein JN (2002) Dorsal root sensitivity to interleukin-1 beta, interleukin-6 and tumor necrosis factor in rats. Eur Spine J 11(5):467-475 (Pubitemid 35232017)
19. Zimmermann M (1983) Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16(2):109-110 (Pubitemid 13058546)
20. Chaplan SR, Bach FW, Pogrel JW, Chung JM, Yaksh TL (1994) Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods 53:55-63 (Pubitemid 24238751)
21. Milligan ED, Mehmert KK, Hinde JL, Harvey LO, Martin D, Tracey KJ, Maier SF, Watkins LR (2000) Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120. Brain Res 861(1):105-116 (Pubitemid 30177288)
22. Ito A, Kumamoto E, Takeda M, Shibata K, Sagai H, Yoshimura M (2000) Mechanisms for ovariectomy-induced hyperalgesia and its relief by calcitonin: participation of 5-HT1A-like receptor on C-afferent terminals in substantiagelatinosa of the rat spinal cord. J Neurosci 20(16):6302-6308 (Pubitemid 30658426)
23. Shibata K, Takeda M, Ito A, Takeda M, Sagai H (1998) Ovariectomy- induced hyperalgesia and antinociceptive effect of elcatonin, a synthetic eel calcitonin. Pharmacol Biochem Behav 60(2):371-376 (Pubitemid 28282677)
24. Ito A, Takeda M, Furue H, Shibata K, Hori M, Sagai H, Sakurada T, Yoshimura M (2004) Administration of estrogen shortly after ovariectomy mimics the anti-nociceptive action and change in 5-HT1A-like receptor expression induced by calcitonin in ovariectomized rats. Bone 35(3):697-703 (Pubitemid 39141871)
25. Chaban VV, Micevych PE (2005) Estrogen receptor-a mediates estradiol attenuation of ATP-induced Ca2? signaling in mouse dorsal root ganglion neurons. J Neurosci Res 81:31-37 (Pubitemid 41139107)
26. Piu F, Cheevers C, Hyldtoft L (2008) Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist. Eur J Pharmacol 590:423-429
27. Zhu X, Luo J, Chen X, Wang J, Wang G, Li H, Xu Y, Feng J, Tu H (2008) Expression characteristic and significance of interleukin- 6, nuclear factor kappa beta, and bone formation markers in rat models of osteoporosis. Transl Res 152(1):18-23
28. Maugeri D, Russo MS, Franzé C, Motta V, Motta M, Destro G, Speciale S, Santangelo A, Panebianco P, Malaguarnera M (1998) Correlations between C-reactive protein, interleukin-6, tumor necrosis factor-alpha and body mass index during senile osteoporosis. Arch Gerontol Geriatr 27(2):159-163 (Pubitemid 28442175)
29. Cunba FQ, Poole S, Lorenzetti BB, Ferreira SH (1992) The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia. Br J Pharmacol 107(3):660-664
30. Ozaktay AC, Kallakuri S, Takebayashi T, Cavanaugh JM, Asik I, DeLeo JA, Weinstein JN (2006) Effects of interleukin-1 beta, interleukin-6, and tumor necrosis factor on sensitivity of dorsal root ganglion and peripheral receptive fields in rats. Eur Spine J 15:1529-1537 (Pubitemid 44583666)
31. Braun J, Sieper J (2003) Overview of the use of the anti-TNF agent infliximab in chronic inflammatory diseases. Expert Opin Biol Ther 3(1):141-168 (Pubitemid 36193658)
32. Kaplanski G, Marin V, Fabrigoule M, Boulay V, Benoliel AM, Bongrand P, Kaplanski S, Farnarier C (1998) Thrombin-activatedhuman endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1;CD106). Blood 92:1259-1267 (Pubitemid 28369039)
33. Henninger DD, Panes J, Eppihimer M, Russell J, Gerritsen M, Anderson DC, Granger DN (1997) Cytokine-induced VCAM-1 and ICAM-1 expression in different organs of the mouse. J Immunol 158:1825-1832 (Pubitemid 127469540)
34. Segond von Banchet G, Boettger MK, Fischer N, Gajda M, Bräuer R, Schaible HG (2009) Experimental arthritis causestumor necrosis factor-alpha-dependent infiltration of macrophages into rat dorsal root ganglia which correlates with painrelated behavior. Pain 145(1-2):151-159