-
1
-
-
84863910803
-
Timing of responses to crizotinib (PF-02341066) in anaplastic lymphoma kinase (ALK)-positive patients with advanced non-small cell lung cancer (NSCLC)
-
(abstr 369)
-
Solomon B, Bang YJ, Camidge DR, et al: Timing of responses to crizotinib (PF-02341066) in anaplastic lymphoma kinase (ALK)-positive patients with advanced non-small cell lung cancer (NSCLC). 22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Berlin, Germany, November 16-19, 2010 (abstr 369)
-
22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Berlin, Germany, November 16-19, 2010
-
-
Solomon, B.1
Bang, Y.J.2
Camidge, D.R.3
-
2
-
-
70349336416
-
Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
-
Shaw AT, Yeap BY, Mino-Kenudson M, et al: Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol 27:4247-4253, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 4247-4253
-
-
Shaw, A.T.1
Yeap, B.Y.2
Mino-Kenudson, M.3
-
3
-
-
79955482290
-
Clinicopathologic characteristics and outcomes of patients with anaplastic lymphoma kinase-positive advanced pulmonary adenocarcinoma: Suggestion for an effective screening strategy for these tumors
-
Koh Y, Kim DW, Kim TM, et al: Clinicopathologic characteristics and outcomes of patients with anaplastic lymphoma kinase-positive advanced pulmonary adenocarcinoma: Suggestion for an effective screening strategy for these tumors. J Thorac Oncol 6:905-912, 2011
-
(2011)
J Thorac Oncol
, vol.6
, pp. 905-912
-
-
Koh, Y.1
Kim, D.W.2
Kim, T.M.3
-
4
-
-
48249114422
-
EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
-
Koivunen JP, Mermel C, Zejnullahu K, et al: EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 14:4275-4283, 2008
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4275-4283
-
-
Koivunen, J.P.1
Mermel, C.2
Zejnullahu, K.3
-
5
-
-
33746961739
-
Mechanisms of Disease: Oncogene addiction - A rationale for molecular targeting in cancer therapy
-
DOI 10.1038/ncponc0558, PII NCPONC0558
-
Weinstein IB, Joe AK: Mechanisms of disease: Oncogene addiction - A rationale for molecular targeting in cancer therapy. Nat Clin Pract Oncol 3:448-457, 2006 (Pubitemid 44203817)
-
(2006)
Nature Clinical Practice Oncology
, vol.3
, Issue.8
, pp. 448-457
-
-
Weinstein, I.B.1
Joe, A.K.2
-
6
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak EL, Bang YJ, Camidge DR, et al: Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 363:1693-1703, 2010
-
(2010)
N Engl J Med
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
-
7
-
-
0036731704
-
Molecular biology of anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma
-
DOI 10.1200/JCO.2002.12.033
-
Kutok JL, Aster JC: Molecular biology of anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma. J Clin Oncol 20:3691-3702, 2002 (Pubitemid 34983230)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.17
, pp. 3691-3702
-
-
Kutok, J.L.1
Aster, J.C.2
-
8
-
-
54049120220
-
Activating mutations in ALK provide a therapeutic target in neuroblastoma
-
George RE, Sanda T, Hanna M, et al: Activating mutations in ALK provide a therapeutic target in neuroblastoma. Nature 455:975-978, 2008
-
(2008)
Nature
, vol.455
, pp. 975-978
-
-
George, R.E.1
Sanda, T.2
Hanna, M.3
-
9
-
-
12144258439
-
The emerging normal and disease-related roles of anaplastic lymphoma kinase
-
DOI 10.1007/s00018-004-4275-9
-
Pulford K, Lamant L, Espinos E, et al: The emerging normal and disease-related roles of anaplastic lymphoma kinase. Cell Mol Life Sci 61:2939-2953, 2004 (Pubitemid 40104592)
-
(2004)
Cellular and Molecular Life Sciences
, vol.61
, Issue.23
, pp. 2939-2953
-
-
Pulford, K.1
Lamant, L.2
Espinos, E.3
Jiang, Q.4
Xue, L.5
Turturro, F.6
Delsol, G.7
Morris, S.W.8
-
10
-
-
0036734911
-
Expression of ALK1 and p80 in inflammatory myofibroblastic tumor and its mesenchymal mimics: A study of 135 cases
-
Cessna MH, Zhou H, Sanger WG, et al: Expression of ALK1 and p80 in inflammatory myofibroblastic tumor and its mesenchymal mimics: A study of 135 cases. Mod Pathol 15:931-938, 2002
-
(2002)
Mod Pathol
, vol.15
, pp. 931-938
-
-
Cessna, M.H.1
Zhou, H.2
Sanger, W.G.3
-
11
-
-
78049426513
-
EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors
-
Choi YL, Soda M, Yamashita Y, et al: EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors. N Engl J Med 363:1734-1739, 2010
-
(2010)
N Engl J Med
, vol.363
, pp. 1734-1739
-
-
Choi, Y.L.1
Soda, M.2
Yamashita, Y.3
-
12
-
-
79960250811
-
Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinase inhibitors
-
Lovly CM, Heuckmann JM, de Stanchina E, et al: Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinase inhibitors. Cancer Res 71:4920-4931, 2011
-
(2011)
Cancer Res
, vol.71
, pp. 4920-4931
-
-
Lovly, C.M.1
Heuckmann, J.M.2
De Stanchina, E.3
-
13
-
-
79955964568
-
CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant
-
Sakamoto H, Tsukaguchi T, Hiroshima S, et al: CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant. Cancer Cell 19:679-690, 2011
-
(2011)
Cancer Cell
, vol.19
, pp. 679-690
-
-
Sakamoto, H.1
Tsukaguchi, T.2
Hiroshima, S.3
-
14
-
-
79956318797
-
Therapeutic strategies to overcome crizotinib resistance in non-small cell lung cancers harboring the fusion oncogene EML4-ALK
-
Katayama R, Khan TM, Benes C, et al: Therapeutic strategies to overcome crizotinib resistance in non-small cell lung cancers harboring the fusion oncogene EML4-ALK. Proc Natl Acad Sci U S A 108:7535-7540, 2011
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 7535-7540
-
-
Katayama, R.1
Khan, T.M.2
Benes, C.3
-
15
-
-
79957896979
-
The Hsp90 inhibitor IPI-504 rapidly lowers EML4-ALK levels and induces tumor regression in ALK-driven NSCLC models
-
Normant E, Paez G, West KA, et al: The Hsp90 inhibitor IPI-504 rapidly lowers EML4-ALK levels and induces tumor regression in ALK-driven NSCLC models. Oncogene 30:2581-2586, 2011
-
(2011)
Oncogene
, vol.30
, pp. 2581-2586
-
-
Normant, E.1
Paez, G.2
West, K.A.3
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