Prospective study of falls and risk factors for falls in adults with advanced cancer

Journal of Clinical Oncology

Volumn 30, Issue 17, 2012, Pages 2128-2133

  Stone, Carol A ^a,b   Lawlor, Peter G ^d   Savva, George M ^b   Bennett, Kathleen ^b   Kenny, Rose Anne ^b,c  

^a Our Lady's Hospice Ltd Dublin   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c ST JAMES S HOSPITAL   (Ireland)

^d BRUYÈRE RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; BENZODIAZEPINE; CORTICOSTEROID; DIAZEPAM; NEUROLEPTIC AGENT;

ADVANCED CANCER; AGED; ANXIETY; ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; BRAIN METASTASIS; BRAIN TUMOR; CANCER PAIN; CANCER PALLIATIVE THERAPY; DEPRESSION; DISEASE SEVERITY; DROWSINESS; FALL RISK; FALL RISK ASSESSMENT; FALLING; FATIGUE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; ORTHOSTATIC HYPOTENSION; PRIORITY JOURNAL; PROSPECTIVE STUDY;

ACCIDENTAL FALLS; AGED; AGING; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; NEOPLASMS; PALLIATIVE CARE; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; REGRESSION ANALYSIS; RISK; RISK FACTORS; TIME FACTORS;

EID: 84863917184     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2011.40.7791     Document Type: Article

References (41)

1. Masud T, Morris RO: Epidemiology of falls. Age Ageing 30:3-7, 2001 (suppl 4)
2. Vellas BJ, Wayne SJ, Romero LJ, et al: Fear of falling and restriction of mobility in elderly fallers. Age Ageing 26:189-193, 1997 (Pubitemid 27290387)
3. Stone CA, Lawlor PG, Kenny RA: How to identify patients with cancer at risk of falling: A review of the evidence. J Palliat Med 14:221-230, 2011
4. Slips, Trips and Falls in Hospital: The Third Report From the Patient Safety Observatory. London, United Kingdom, National Patient Safety Agency, 2007
5. Higginson I, Davies E (eds): Better Palliative Care for Older People. Copenhagen, Denmark, WHO, 2004
6. Mohile SG, Fan L, Reeve E, et al: Association of cancer with geriatric syndromes in older Medicare beneficiaries. J Clin Oncol 29:1458-1464, 2011
7. Pearse H, Nicholson L, Bennett M: Falls in hospices: A cancer network observational study of fall rates and risk factors. Palliat Med 18:478-481, 2004 (Pubitemid 39162661)
8. Pautex S, Herrmann FR, Zulian GB: Factors associated with falls in patients with cancer hospitalized for palliative care. J Palliat Med 11:878-884, 2008
9. O'Connell B, Cockayne M, Wellman D, et al: Fall risk factors and the nature of falls in inpatient oncology and palliative care settings. Contemp Nurse 18:247-257, 2005
10. Goodridge D, Marr H: Factors associated with falls in an inpatient palliative care unit: An exploratory study. Int J Palliat Nurs 8:548-556, 2002
11. Katzman R, Brown T, Fuld P, et al: Validation of a short Orientation-Memory-Concentration Test of cognitive impairment. Am J Psychiatry 140:734-739, 1983 (Pubitemid 13094139)
12. Summary of the Updated American Geriatrics Society/British Geriatrics Society clinical practice guideline for prevention of falls in older persons. J Am Geriatr Soc 59:148-157, 2011
13. Ewing DJ, Martyn CN, Young RJ, et al: The value of cardiovascular autonomic function tests: 10 years experience in diabetes. Diabetes Care 8:491-498, 1985 (Pubitemid 15240914)
14. Stone CA, Kenny RA, Nolan B, et al: Autonomic dysfunction in patients with advanced cancer; prevalence, clinical correlates and challenges in assessment. BMC Palliat Care 11:3, 2012
15. Freeman R, Wieling W, Axelrod FB, et al: Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res 21:69-72, 2011
16. Muscaritoli M, Anker SD, Argilés J, et al: Consensus definition of sarcopenia, cachexia and pre-cachexia: Joint document elaborated by Special Interest Groups (SIG) "cachexia-anorexia in chronic wasting diseases" and "nutrition in geriatrics." Clin Nutr 29:154-159, 2010
17. Corish CA, Kennedy NP: Anthropometric measurements from a cross-sectional survey of Irish free-living elderly subjects with smoothed centile curves. Br J Nutr 89:137-145, 2003 (Pubitemid 36187546)
18. Landi F, Liperoti R, Fusco D, et al: Prevalence and risk factors of sarcopenia among nursing home older residents. J Gerontol A Biol Sci Med Sci 67:48-55, 2012
19. Evans WJ, Morley JE, Argilés J, et al: Cachexia: A new definition. Clin Nutr 27:793-799, 2008
20. Podsiadlo D, Richardson S: The timed "Up & Go": A test of basic functional mobility for frail elderly persons. J Am Geriatr Soc 39:142-148, 1991
21. Lord SR: Visual risk factors for falls in older people. Age Ageing 35:ii42-ii45, 2006 (suppl 2)
22. Martina I, van Koningsveld R, Schmitz PI, et al: Measuring vibration threshold with a graduated tuning fork in normal aging and in patients with polyneuropathy. J Neurol Neurosurg Psychiatry 743-747, 1998
23. Lord S, Sherrington C, Menz H, et al: Falls in Older People: Risk Factors and Strategies for Prevention (ed 2). Cambridge, United Kingdom, Cambridge University Press, 2007
24. Ashton CH: Benzodiazepines: How They Work and How to Withdraw. Newcastle upon Tyne, United Kingdom, University of Newcastle, 2002
25. Anderson F, Downing GM, Hill J, et al: Palliative performance scale (PPS): A new tool. J Palliat Care 12:5-11, 1996 (Pubitemid 126672217)
26. Fainsinger RL, Nekolaichuk CL: A "TNM" classification system for cancer pain: The Edmonton Classification System for Cancer Pain (ECS-CP). Support Care Cancer 16:547-555, 2008
27. Bruera E, Kuehn N, Miller MJ, et al: The Edmonton Symptom Assessment System (ESAS): A simple method for the assessment of palliative care patients. J Palliat Care 7:6-9, 1991
28. Savard MH, Savard J, Simard S, et al: Empirical validation of the Insomnia Severity Index in cancer patients. Psychooncology 14:429-441, 2005 (Pubitemid 40883415)
29. Espuña-Pons M, Dilla T, Castro D, et al: Analysis of the value of the ICIQ-UI SF questionnaire and stress test in the differential diagnosis of the type of urinary incontinence. Neurourol Urodyn 26:836-841, 2007 (Pubitemid 47548251)
30. Davison J, Bond J, Dawson P, et al: Patients with recurrent falls attending accident and emergency benefit from multifactorial intervention: A randomised controlled trial. Age Ageing 34:162-168, 2005 (Pubitemid 40331099)
31. Allan LM, Ballard CG, Rowan EN, et al: Incidence and prediction of falls in dementia: A prospective study in older people. PLoS ONE 4:e5521, 2009
32. Ganz DA, Bao Y, Shekelle PG, et al: Will my patient fall? JAMA 297:77-86, 2007 (Pubitemid 46041729)
33. Tinetti ME, Kumar C: The patient who falls: "It's always a trade-off". JAMA 303:258-266, 2010
34. Darowski A, Chambers SA, Chambers DJ: Antidepressants and falls in the elderly. Drugs Aging 26:381-394, 2009
35. Whooley MA, Kip KE, Cauley JA, et al: Depression, falls, and risk of fracture in older women. Arch Intern Med 159:484-490, 1999 (Pubitemid 29108914)
36. Anstey KJ, Burns R, von Sanden C, et al: Psychological well-being is an independent predictor of falling in an 8-year follow-up of older adults. J Gerontol B Psychol Sci Soc Sci 63:P249-P257, 2008
37. Deshpande N, Metter EJ, Lauretani F, et al: Activity restriction induced by fear of falling and objective and subjective measures of physical function: A prospective cohort study. J Am Geriatr Soc 56:615-620, 2008 (Pubitemid 351473533)
38. Pluijm SM, Smit JH, Tromp EA, et al: A risk profile for identifying community-dwelling elderly with a high risk of recurrent falling: Results of a 3-year prospective study. Osteoporos Int 17:417-425, 2006
39. McCarthy F, Fan CW, Kearney PM, et al: What is the evidence for cardiovascular disorders as a risk factor for non-syncopal falls? Scope for future research. Eur Geriatr Med 1:244-251, 2010
40. Ling J, Rees E, Hardy J: What influences participation in clinical trials in palliative care in a cancer centre? Eur J Cancer 36:621-626, 2000 (Pubitemid 30156848)
41. Oliver D: Falls risk-prediction tools for hospital inpatients: Time to put them to bed? Age Ageing 37:248-250, 2008