메뉴 건너뛰기




Volumn 55, Issue 3, 2012, Pages 418-425

Hepatitis C treatment highlights from the 2011 American association for the study of liver disease meeting

Author keywords

[No Author keywords available]

Indexed keywords

ACH 1625; ANTIVIRUS AGENT; ASUNAPREVIR; BI 207127; BOCEPREVIR; DACLATASVIR; DANOPREVIR; FALDAPREVIR; GSK 2336805; IDX 08189; MERICITABINE; MK 4882; MK 5172; N (2' DEOXY 2' FLUORO 2' METHYL P PHENYL 5' URIDYLYL)ALANINE ISOPROPYL ESTER; NARLAPREVIR; PEGINTERFERON; PPI 461; RIBAVIRIN; SIMEPREVIR; TELAPREVIR; TMC 647055; UNCLASSIFIED DRUG; VANIPREVIR; VX 222;

EID: 84863917117     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cis375     Document Type: Article
Times cited : (7)

References (63)
  • 1
    • 79953176289 scopus 로고    scopus 로고
    • Boceprevir for previously treated chronic HCV genotype 1 infection
    • Bacon BR, Gordon SC, Lawitz E, et al. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med 2011; 364:1207-17.
    • (2011) N Engl J Med , vol.364 , pp. 1207-1217
    • Bacon, B.R.1    Gordon, S.C.2    Lawitz, E.3
  • 2
    • 79959438789 scopus 로고    scopus 로고
    • Telaprevir for previously untreated chronic hepatitis C virus infection
    • Jacobson IM, McHutchison JG, Dusheiko G, et al. Telaprevir for previously untreated chronic hepatitis C virus infection. N Engl J Med 2011; 364:2405-16.
    • (2011) N Engl J Med , vol.364 , pp. 2405-2416
    • Jacobson, I.M.1    McHutchison, J.G.2    Dusheiko, G.3
  • 3
    • 79953173221 scopus 로고    scopus 로고
    • Boceprevir for untreated chronic HCV genotype 1 infection
    • Poordad F, McCone J Jr, Bacon BR, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011; 364:1195-206.
    • (2011) N Engl J Med , vol.364 , pp. 1195-1206
    • Poordad, F.1    McCone Jr., J.2    Bacon, B.R.3
  • 4
    • 79959381354 scopus 로고    scopus 로고
    • Telaprevir for retreatment of HCV infection
    • Zeuzem S, Andreone P, Pol S, et al. Telaprevir for retreatment of HCV infection. N Engl J Med 2011; 364:2417-28.
    • (2011) N Engl J Med , vol.364 , pp. 2417-2428
    • Zeuzem, S.1    Andreone, P.2    Pol, S.3
  • 5
    • 80053339008 scopus 로고    scopus 로고
    • An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases
    • Ghany MG, Nelson DR, Strader DB, Thomas DL, Seeff LB. An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases. Hepatology 2011; 54:1433-44.
    • (2011) Hepatology , vol.54 , pp. 1433-1444
    • Ghany, M.G.1    Nelson, D.R.2    Strader, D.B.3    Thomas, D.L.4    Seeff, L.B.5
  • 6
    • 79960453276 scopus 로고    scopus 로고
    • EASL clinical practice guidelines: Management of hepatitis C virus infection
    • Craxi A, Pawlotskly JM, Wedemeyer H, et al. EASL clinical practice guidelines: management of hepatitis C virus infection. J Hepatol 2011; 55:245-64.
    • (2011) J Hepatol , vol.55 , pp. 245-264
    • Craxi, A.1    Pawlotskly, J.M.2    Wedemeyer, H.3
  • 7
    • 84863886080 scopus 로고    scopus 로고
    • Predictors of sustained virologic response (SVR) among poor interferon (IFN) responders when boceprevir (BOC) is added to peginterferon alfa-2B/ribavirin (PR; Abstract 33)
    • San Francisco: Hepatology
    • Bacon BR, Bruno S, Schiff ER, et al. Predictors of sustained virologic response (SVR) among poor interferon (IFN) responders when boceprevir (BOC) is added to peginterferon alfa-2B/ribavirin (PR; abstract 33). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco: Hepatology, 2011:376A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Bacon, B.R.1    Bruno, S.2    Schiff, E.R.3
  • 10
    • 84858176737 scopus 로고    scopus 로고
    • Treatment with the second generation HCV protease inhibitor BI201335 results in high and consistent SVR rates: Results from SILEN-C1 in treatment naive patients across different baseline factors (abstract 226)
    • San Francisco, USA: Hepatology
    • Sulkowski MS, Asselah T, Ferenci P, et al. Treatment with the second generation HCV protease inhibitor BI201335 results in high and consistent SVR rates: results from SILEN-C1 in treatment naive patients across different baseline factors (abstract 226). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:473A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Sulkowski, M.S.1    Asselah, T.2    Ferenci, P.3
  • 12
    • 84856906043 scopus 로고    scopus 로고
    • TMC435 in combination with peginterferon and ribavirin in treatment-naive HCV genotype 1 patients: Final analysis of the PILLAR phase IIB study (abstract LB-5)
    • San Francisco, USA: Hepatology
    • Fried MW, Buti M, Dore GJ, et al. TMC435 in combination with peginterferon and ribavirin in treatment-naive HCV genotype 1 patients: final analysis of the PILLAR phase IIB study (abstract LB-5). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:1429A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Fried, M.W.1    Buti, M.2    Dore, G.J.3
  • 13
    • 84863524062 scopus 로고    scopus 로고
    • High sustained virologic resonse (SVR24) rates with response-guided danoprevir (DNV; RG7227) plus PEGIFN α-2A (40KD) and ribavirin (P/R) in treatment-naive HCV genotype 1 (G1) patients: Results from the Atlas study (abstract 79)
    • San Francisco, USA: Hepatology
    • Terrault N, Cooper C, Balart LA, et al. High sustained virologic resonse (SVR24) rates with response-guided danoprevir (DNV; RG7227) plus PEGIFN α-2A (40KD) and ribavirin (P/R) in treatment-naive HCV genotype 1 (G1) patients: results from the Atlas study (abstract 79). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:398A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Terrault, N.1    Cooper, C.2    Balart, L.A.3
  • 14
    • 84869218752 scopus 로고    scopus 로고
    • Once daily narlaprevir (NVR; SCH 900518) and ritonavir (RTV) in combination with peginterferon alfa-2B/ribavirin (PR) for 12 weeks plus 12 weeks PR in treatmentnaive patients with HCV genotype 1 (G1): SVR results from NEXT-1, a phase 2 study (abstract LB-17)
    • San Francisco, USA: Hepatology
    • Vierling JM, Poordad F, Lawitz E, et al. Once daily narlaprevir (NVR; SCH 900518) and ritonavir (RTV) in combination with peginterferon alfa-2B/ribavirin (PR) for 12 weeks plus 12 weeks PR in treatmentnaive patients with HCV genotype 1 (G1): SVR results from NEXT-1, a phase 2 study (abstract LB-17). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:1437A-8A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Vierling, J.M.1    Poordad, F.2    Lawitz, E.3
  • 15
    • 84863943770 scopus 로고    scopus 로고
    • BMS-790052, A NS5A replication complex inhibitor, combined with peginterferon alfa-2A and ribivirin in treatment-naive HCV genotype 1 or 4 patients: Phase 2B AI444010 study interim week 12 results (abstract 227)
    • San Francisco, USA: Hepatology
    • Hezode C, Hirschfield GM, Ghesquiere W, et al. BMS-790052, A NS5A replication complex inhibitor, combined with peginterferon alfa-2A and ribivirin in treatment-naive HCV genotype 1 or 4 patients: phase 2B AI444010 study interim week 12 results (abstract 227). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:474A-5A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Hezode, C.1    Hirschfield, G.M.2    Ghesquiere, W.3
  • 16
    • 84863915200 scopus 로고    scopus 로고
    • Combination therapy of treatment-naive and nonresponder patients with HCV genotype 1 infection with BMS-790052, an NS5A replication complex inhibitor, in combination with peginterferon alfa-2A and ribavirin (abstract LB-20)
    • San Francisco, USA: Hepatology
    • Izumi N, Asahina Y, Yokosuka O, et al. Combination therapy of treatment-naive and nonresponder patients with HCV genotype 1 infection with BMS-790052, an NS5A replication complex inhibitor, in combination with peginterferon alfa-2A and ribavirin (abstract LB-20). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:1439A-40A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Izumi, N.1    Asahina, Y.2    Yokosuka, O.3
  • 17
    • 84866789705 scopus 로고    scopus 로고
    • BMS-790052, an NS5A replication complex inhibitor, in combination with peginterferon alpha-2B and ribavirin in Japanese treatment-naive and nonresponder patients with chronic HCV genotype 1 infection (abstract LB-22)
    • San Francisco, USA: Hepatology
    • Suzuki F, Chayama K, Kawakami Y, et al. BMS-790052, an NS5A replication complex inhibitor, in combination with peginterferon alpha-2B and ribavirin in Japanese treatment-naive and nonresponder patients with chronic HCV genotype 1 infection (abstract LB-22). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:1441A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Suzuki, F.1    Chayama, K.2    Kawakami, Y.3
  • 18
    • 84855233736 scopus 로고    scopus 로고
    • Once-daily PSI-7977 plus PEG/RBV in treatment naive patients with HCV GT1: Robust end of treatment response rates are sustained post-treatment (abstract 225)
    • San Francisco, USA: Hepatology
    • Lawitz E, Lalezari JP, Hassanein T, et al. Once-daily PSI-7977 plus PEG/RBV in treatment naive patients with HCV GT1: robust end of treatment response rates are sustained post-treatment (abstract 225). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:472A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Lawitz, E.1    Lalezari, J.P.2    Hassanein, T.3
  • 22
    • 80051915933 scopus 로고    scopus 로고
    • VX-222 with TVR alone or in combination with pegInterferon alfa-2A and ribavirin in treatment-naïve patients with chronic hepatitis C: ZENITH study interim results (abstract 1363)
    • Berlin, Germany: Journal of Hepatology
    • Di Bisceglie AM, Nelson DR, Gane E, et al. VX-222 with TVR alone or in combination with pegInterferon alfa-2A and ribavirin in treatment-naïve patients with chronic hepatitis C: ZENITH study interim results (abstract 1363). The International Liver Congress (2011) 46th Annual Meeting of the European Association for the Study of the Liver. Vol. 54. Berlin, Germany: Journal of Hepatology, 2011:S540.
    • (2011) The International Liver Congress (2011) 46th Annual Meeting of the European Association for the Study of the Liver , vol.54
    • Di Bisceglie, A.M.1    Nelson, D.R.2    Gane, E.3
  • 24
    • 84866776146 scopus 로고    scopus 로고
    • GSK2336805 HCV NS5A inhibitor demonstrates potent antiviral activity in chronic genotype 1 infections; Results from a first time in human (FTIH) single and repeat dose study (abstract 83)
    • San Francisco, USA: Hepatology
    • Spreen W, Wilfret DA, Bechtel J, et al. GSK2336805 HCV NS5A inhibitor demonstrates potent antiviral activity in chronic genotype 1 infections; Results from a first time in human (FTIH) single and repeat dose study (abstract 83). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:400A-1A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Spreen, W.1    Wilfret, D.A.2    Bechtel, J.3
  • 25
    • 84857868101 scopus 로고    scopus 로고
    • Dual oral combination therapy with the NS5A inhibitor BMS-790052 and the NS3 protease inhibitor BMS-650032 achieved 90% sustained virologic response (SVR12) in HCV genotype 1B-infected null responders (abstract LB-4)
    • San Francisco, USA: Hepatology
    • Chayama K, Takahashi S, Kawakami Y, et al. Dual oral combination therapy with the NS5A inhibitor BMS-790052 and the NS3 protease inhibitor BMS-650032 achieved 90% sustained virologic response (SVR12) in HCV genotype 1B-infected null responders (abstract LB-4). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:1428A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Chayama, K.1    Takahashi, S.2    Kawakami, Y.3
  • 26
    • 78650942343 scopus 로고    scopus 로고
    • Strong antiviral activity and safety of IFN-sparing treatment with the protease inhibitor BI 201335, the HCV polymerase inhibitor BI 207127 and ribavirin in patients with chronic hepatitis C (abstract LB-7)
    • Boston, USA: Hepatology
    • Zeuzem S, Asselah T, Angus PW, et al. Strong antiviral activity and safety of IFN-sparing treatment with the protease inhibitor BI 201335, the HCV polymerase inhibitor BI 207127 and ribavirin in patients with chronic hepatitis C (abstract LB-7). The Liver Meeting (2010) 61st Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 52. Boston, USA: Hepatology, 2010:223A.
    • (2010) The Liver Meeting (2010) 61st Annual Meeting of the American Association for the Study of Liver Diseases , vol.52
    • Zeuzem, S.1    Asselah, T.2    Angus, P.W.3
  • 27
    • 84856293564 scopus 로고    scopus 로고
    • Virologic response to an interferon-free regimen of BI201335 and BI207127 with and without ribavirin in treatment naive patients with chronic genotype 1 HCV infection: Week 12 interim results of the SOUND-C2 study (abstract LB-15)
    • San Fransisco, USA: Hepatology
    • Zeuzem S, Soriano V, Asselah T, et al. Virologic response to an interferon-free regimen of BI201335 and BI207127 with and without ribavirin in treatment naive patients with chronic genotype 1 HCV infection: week 12 interim results of the SOUND-C2 study (abstract LB-15). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Fransisco, USA: Hepatology, 2011:1436A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Zeuzem, S.1    Soriano, V.2    Asselah, T.3
  • 28
    • 65449171953 scopus 로고    scopus 로고
    • Telaprevir and peginterferon with or without ribavirin for chronic HCV infection
    • Hezode C, Forestier N, Dusheiko G, et al. Telaprevir and peginterferon with or without ribavirin for chronic HCV infection. N Engl J Med 2009; 360:1839-50.
    • (2009) N Engl J Med , vol.360 , pp. 1839-1850
    • Hezode, C.1    Forestier, N.2    Dusheiko, G.3
  • 29
    • 84855248040 scopus 로고    scopus 로고
    • Once daily PSI-7977 plus RBV: Pegylated interfron-alfa not required for complete rapid viral response in treatment-naive patients with HCV GT2 or GT3 (abstract 34)
    • San Francisco, USA: Hepatology
    • Gane EJ, Stedman CA, Hyland RH, et al. Once daily PSI-7977 plus RBV: pegylated interfron-alfa not required for complete rapid viral response in treatment-naive patients with HCV GT2 or GT3 (abstract 34). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:377A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Gane, E.J.1    Stedman, C.A.2    Hyland, R.H.3
  • 30
    • 81855228070 scopus 로고    scopus 로고
    • Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection
    • quiz e14
    • Zeuzem S, Asselah T, Angus P, et al. Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection. Gastroenterology 2011; 141:2047-55; quiz e14.
    • (2011) Gastroenterology , vol.141 , pp. 2047-2055
    • Zeuzem, S.1    Asselah, T.2    Angus, P.3
  • 31
    • 84867688570 scopus 로고    scopus 로고
    • Analysis of resistanceassociated amino acid variants (RAVS) in non-SVR patients enrolled in a retrospective long-term follow-up analysis of boceprevir phase 3 clinical studies (abstract 164)
    • San Fransisco, USA: Hepatology
    • Barnard RJ, Zeuzem S, Vierling JM, et al. Analysis of resistanceassociated amino acid variants (RAVS) in non-SVR patients enrolled in a retrospective long-term follow-up analysis of boceprevir phase 3 clinical studies (abstract 164). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Fransisco, USA: Hepatology, 2011:440A-1A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Barnard, R.J.1    Zeuzem, S.2    Vierling, J.M.3
  • 33
    • 84455204688 scopus 로고    scopus 로고
    • Long-term outcomes following combination treatment with boceprevir plus peg-intron/ribavirin (P/R) in patients with chronic hepatitis C, genotype 1 (CHC-G1; Abstract 2016)
    • Vienna, Austria: Journal of Hepatology
    • Vierling JM, Ralston R, Lawitz E, et al. Long-term outcomes following combination treatment with boceprevir plus peg-intron/ribavirin (P/R) in patients with chronic hepatitis C, genotype 1 (CHC-G1; abstract 2016). The International Liver Congress (2010)-45th Annual Meeting of the European Association for the Study of the Liver. Vol. 52. Vienna, Austria: Journal of Hepatology, 2010:S470-S1.
    • (2010) The International Liver Congress (2010)-45th Annual Meeting of the European Association for the Study of the Liver , vol.52
    • Vierling, J.M.1    Ralston, R.2    Lawitz, E.3
  • 34
    • 84863931212 scopus 로고    scopus 로고
    • Retreatment with telaprevir/PEG-IFN/RBV after a short exposure to telaprevir in phase 1 studies: Interim results from a phase IIIB rollover trial (C219; Abstract 35)
    • San Francisco, USA: Hepatology
    • Sarrazin C, Reesink HW, Zeuzem S, et al. Retreatment with telaprevir/PEG-IFN/RBV after a short exposure to telaprevir in phase 1 studies: interim results from a phase IIIB rollover trial (C219; abstract 35). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:377A-8A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Sarrazin, C.1    Reesink, H.W.2    Zeuzem, S.3
  • 35
    • 78349268362 scopus 로고    scopus 로고
    • RG7128 alone or in combination with pegylated interferon-alpha2a and ribavirin prevents hepatitis C virus (HCV) replication and selection of resistant variants in HCV-infected patients
    • Le Pogam S, Seshaadri A, Ewing A, et al. RG7128 alone or in combination with pegylated interferon-alpha2a and ribavirin prevents hepatitis C virus (HCV) replication and selection of resistant variants in HCV-infected patients. J Infect Dis 2010; 202:1510-9.
    • (2010) J Infect Dis , vol.202 , pp. 1510-1519
    • Le Pogam, S.1    Seshaadri, A.2    Ewing, A.3
  • 36
    • 79960453114 scopus 로고    scopus 로고
    • First SVR data with the nucleoside analogue polymerase inhibitor Mericitabine (RG7128) combined with peginterferon/ribavirin in treatment-naive HCV G1/4 patients: Interim analysis from the JUMP-C trial (abstract 1359)
    • Berlin, Germany: Journal of Hepatology
    • Pockros P, Jensen D, Tsai N, et al. First SVR data with the nucleoside analogue polymerase inhibitor Mericitabine (RG7128) combined with peginterferon/ribavirin in treatment-naive HCV G1/4 patients: interim analysis from the JUMP-C trial (abstract 1359). The International Liver Congress (2011) 46th Annual Meeting of the European Association for the Study of the Liver. Vol. 54. Berlin, Germany: Journal of Hepatology, 2011:S538.
    • (2011) The International Liver Congress (2011) 46th Annual Meeting of the European Association for the Study of the Liver , vol.54
    • Pockros, P.1    Jensen, D.2    Tsai, N.3
  • 37
    • 79960446187 scopus 로고    scopus 로고
    • Once daily alisporivir (DEB025) plus PEGIFNALFA2A/ribavirin results in superior sustained virologic response (SVR24) in chronic hepatitis C genotype 1 treatment naive patients (abstract 4)
    • Berlin, Germany: Journal of Hepatology
    • Flisiak R, Pawlotsky JM, Crabbe R, et al. Once daily alisporivir (DEB025) plus PEGIFNALFA2A/ribavirin results in superior sustained virologic response (SVR24) in chronic hepatitis C genotype 1 treatment naive patients (abstract 4). The International Liver Congress (2011) 46th Annual Meeting of the European Association for the Study of the Liver. Vol. 54. Berlin, Germany: Journal of Hepatology, 2011:S2.
    • (2011) The International Liver Congress (2011) 46th Annual Meeting of the European Association for the Study of the Liver , vol.54
    • Flisiak, R.1    Pawlotsky, J.M.2    Crabbe, R.3
  • 39
    • 84863942019 scopus 로고    scopus 로고
    • Alisporivir - A host-targeting antiviral, provides low viral breakthrough rate and high barrier to resistance in HCV genotype 1 treatment-naive patients in the phase IIB ESSENTIAL study (abstract 1350)
    • San Francisco, USA: Hepatology
    • Li B, Snoeck J, Tang Y, et al. Alisporivir-a host-targeting antiviral, provides low viral breakthrough rate and high barrier to resistance in HCV genotype 1 treatment-naive patients in the phase IIB ESSENTIAL study (abstract 1350). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:997A-8A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Li, B.1    Snoeck, J.2    Tang, Y.3
  • 40
    • 84863978133 scopus 로고    scopus 로고
    • Once daily alisporivir interferon (IFN)-free regimens achieve high rates of early HCV clearance in previously untreated patients with HCV genotype (G) 2 or 3 (abstract LB-11)
    • San Francisco, USA: Hepatology
    • Pawlotskly JM, Flisiak R, Rasenack J, et al. Once daily alisporivir interferon (IFN)-free regimens achieve high rates of early HCV clearance in previously untreated patients with HCV genotype (G) 2 or 3 (abstract LB-11). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:1433A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Pawlotskly, J.M.1    Flisiak, R.2    Rasenack, J.3
  • 41
    • 84863902729 scopus 로고    scopus 로고
    • Nitazoxanide exhibits synergy with HCV protease inhibitors and prevents the emergence of telaprevir-resistant HCV mutants in combination treatments in cell culture (abstract 377)
    • San Francisco, USA: Hepatology
    • Korba B, Farrar KE, Yon C. Nitazoxanide exhibits synergy with HCV protease inhibitors and prevents the emergence of telaprevir-resistant HCV mutants in combination treatments in cell culture (abstract 377). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:546A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Korba, B.1    Farrar, K.E.2    Yon, C.3
  • 42
    • 60449108708 scopus 로고    scopus 로고
    • Improved virologic response in chronic hepatitis C genotype 4 treated with nitazoxanide, peginterferon, and ribavirin
    • Rossignol JF, Elfert A, El-Gohary Y, Keeffe EB. Improved virologic response in chronic hepatitis C genotype 4 treated with nitazoxanide, peginterferon, and ribavirin. Gastroenterology 2009; 136:856-62.
    • (2009) Gastroenterology , vol.136 , pp. 856-862
    • Rossignol, J.F.1    Elfert, A.2    El-Gohary, Y.3    Keeffe, E.B.4
  • 43
    • 84863947355 scopus 로고    scopus 로고
    • Neither vitamin D levels nor genetic polymorphisms within the 25-, and the 1α? vitamin D hydroxylase are associated with viral clearance following interferonbased therapy in patients with genotype 1 chronic hepatitis C (abstract 1332)
    • San Francisco, USA: Hepatology
    • Grammatikos G, Susser S, Schwendy S, et al. Neither vitamin D levels nor genetic polymorphisms within the 25-, and the 1α? vitamin D hydroxylase are associated with viral clearance following interferonbased therapy in patients with genotype 1 chronic hepatitis C (abstract 1332). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:987A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Grammatikos, G.1    Susser, S.2    Schwendy, S.3
  • 45
    • 80055060055 scopus 로고    scopus 로고
    • Vitamin D: An innate antiviral agent suppressing hepatitis C virus in human hepatocytes
    • Gal-Tanamy M, Bachmetov L, Ravid A, et al. Vitamin D: an innate antiviral agent suppressing hepatitis C virus in human hepatocytes. Hepatology 2011; 54:1570-9.
    • (2011) Hepatology , vol.54 , pp. 1570-1579
    • Gal-Tanamy, M.1    Bachmetov, L.2    Ravid, A.3
  • 47
    • 78650457786 scopus 로고    scopus 로고
    • Statin therapy improves sustained virologic response among diabetic patients with chronic hepatitis C
    • Rao GA, Pandya PK. Statin therapy improves sustained virologic response among diabetic patients with chronic hepatitis C. Gastroenterology 2011; 140:144-52.
    • (2011) Gastroenterology , vol.140 , pp. 144-152
    • Rao, G.A.1    Pandya, P.K.2
  • 49
    • 77950602195 scopus 로고    scopus 로고
    • Pioglitazone improves virological response to peginterferon alpha-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance
    • Khattab M, Emad M, Abdelaleem A, et al. Pioglitazone improves virological response to peginterferon alpha-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance. Liver Int 2010; 30:447-54.
    • (2010) Liver Int , vol.30 , pp. 447-454
    • Khattab, M.1    Emad, M.2    Abdelaleem, A.3
  • 51
    • 84863972763 scopus 로고    scopus 로고
    • Selective estrogen receptor modulator enhances the efficacy of pegylated interferon alpha plus ribavirin treatment for menopausal women with chronic hepatitis C (abstract LB-27)
    • San Francisco, USA: Hepatology
    • Furusyo N, Murata M, Ogawa E, et al. Selective estrogen receptor modulator enhances the efficacy of pegylated interferon alpha plus ribavirin treatment for menopausal women with chronic hepatitis C (abstract LB-27). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco, USA: Hepatology, 2011:1444A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Furusyo, N.1    Murata, M.2    Ogawa, E.3
  • 53
    • 84863924983 scopus 로고    scopus 로고
    • Projections using decision-analytic modeling of long-term clinical value of telaprevir for the treatment of HCV patients who had failed prior pegInterferon/ribavirin treatment (abstract 943)
    • San Francisco: Hepatology
    • Deniz B, Brogan A, Miller J, Talbird S, Thompson J. Projections using decision-analytic modeling of long-term clinical value of telaprevir for the treatment of HCV patients who had failed prior pegInterferon/ribavirin treatment (abstract 943). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco: Hepatology, 2011:802A-3A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Deniz, B.1    Brogan, A.2    Miller, J.3    Talbird, S.4    Thompson, J.5
  • 55
    • 84860265354 scopus 로고    scopus 로고
    • The cost-effectiveness of a telaprevirinclusive regimen as initial therapy for genotype 1 hepatitis C infection in individuals with the CC IL-28B polymorphism (abstract 118)
    • San Francisco: Hepatology
    • Gellad Z, Naggie S, Reed S, et al. The cost-effectiveness of a telaprevirinclusive regimen as initial therapy for genotype 1 hepatitis C infection in individuals with the CC IL-28B polymorphism (abstract 118). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Disease. Vol. 54. San Francisco: Hepatology, 2011:417A-8A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Disease , vol.54
    • Gellad, Z.1    Naggie, S.2    Reed, S.3
  • 56
    • 84863975285 scopus 로고    scopus 로고
    • Safety and antiviral activity of MK-5172, a next generation HCV NS3/4A protease inhibitor with a broad HCV genotypic activity spectrum and potent activity against known resistance mutants, in genotype 1 and 3 HCV-infected patients (abstract 346)
    • San Francisco: Hepatology
    • Petry A, Fraser I, O'Mara E, et al. Safety and antiviral activity of MK-5172, a next generation HCV NS3/4A protease inhibitor with a broad HCV genotypic activity spectrum and potent activity against known resistance mutants, in genotype 1 and 3 HCV-infected patients (abstract 346). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Disease. Vol. 54. San Francisco: Hepatology, 2011:531A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Disease , vol.54
    • Petry, A.1    Fraser, I.2    O'Mara, E.3
  • 57
    • 84863941855 scopus 로고    scopus 로고
    • Safety and efficacy of vaniprevir (MK-7009) in combination with peg-interferon alfa-2A (PEG-IFN)/ribavirin (RBV) in genotype 1 treatment experienced HIV-infected Japanese patients (abstract 1347)
    • San Francisco: Hepatology
    • Hayashi N, Nakamura K, Wright D, et al. Safety and efficacy of vaniprevir (MK-7009) in combination with peg-interferon alfa-2A (PEG-IFN)/ribavirin (RBV) in genotype 1 treatment experienced HIV-infected Japanese patients (abstract 1347). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco: Hepatology, 2011: 996A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Hayashi, N.1    Nakamura, K.2    Wright, D.3
  • 58
    • 84863922004 scopus 로고    scopus 로고
    • A phase 2B study of MK-7009 (vaniprevir) in patients with genotype 1 HCV infection who have failed previous pegylated interferon and ribavirin treatment (abstract LB-13)
    • San Francisco: Hepatology
    • Lawitz E, Rodriguez-Torres M, Stoehr A, et al. A phase 2B study of MK-7009 (vaniprevir) in patients with genotype 1 HCV infection who have failed previous pegylated interferon and ribavirin treatment (abstract LB-13). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco: Hepatology, 2011:1434A-5A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Lawitz, E.1    Rodriguez-Torres, M.2    Stoehr, A.3
  • 61
    • 84863938278 scopus 로고    scopus 로고
    • High sustained virologic response (SVR 24) rates with response-guided danoprevir (DNV; RG7227) plus PEGIFN α-2A (40KD) and ribavirin (P/R) in treatment-naïve HCV genotype 1 (G1) patients: Results from the ATLAS study (abstract 80)
    • San Francisco: Hepatology
    • Guedj J, Dahari H, Tafoya E, Smith PF, Perelson AS. High sustained virologic response (SVR 24) rates with response-guided danoprevir (DNV; RG7227) plus PEGIFN α-2A (40KD) and ribavirin (P/R) in treatment-naïve HCV genotype 1 (G1) patients: Results from the ATLAS study (abstract 80). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases. Vol. 54. San Francisco: Hepatology, 2011:399A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Guedj, J.1    Dahari, H.2    Tafoya, E.3    Smith, P.F.4    Perelson, A.S.5
  • 62
    • 84890312082 scopus 로고    scopus 로고
    • Antiviral activity and safety of INX-08189, a nucleotide polymerase inhibitor, following 7-days of oral therapy in naïve genotype 1 chronic HCV patients (abstract 354)
    • San Francisco: Hepatology
    • Rodriguez-Torres M, Lawitz E, Hazan L, et al. Antiviral activity and safety of INX-08189, a nucleotide polymerase inhibitor, following 7-days of oral therapy in naïve genotype 1 chronic HCV patients (abstract 354). The Liver Meeting (2011) The 62nd Annual Meeting of the American Association for the Study of Liver Diseases Vol. 54. San Francisco: Hepatology, 2011:535A.
    • (2011) The Liver Meeting (2011) the 62nd Annual Meeting of the American Association for the Study of Liver Diseases , vol.54
    • Rodriguez-Torres, M.1    Lawitz, E.2    Hazan, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.