Prevention of pegfilgrastim-induced bone pain: A phase III double-blind placebo-controlled randomized clinical trial of the University of Rochester Cancer Center Clinical Community Oncology Program research base

Journal of Clinical Oncology

Volumn 30, Issue 16, 2012, Pages 1974-1979

  Kirshner, Jeffrey J ^a   Heckler, Charles E ^b   Janelsins, Michelle C ^b   Dakhil, Shaker R ^c   Hopkins, Judith O ^d   Coles, Charlotte ^e   Morrow, Gary R ^b  

^a Hematology Oncology Associates of Central New York   (United States)

^b UNIVERSITY OF ROCHESTER   (United States)

^c WICHITA COMMUNITY CLINICAL ONCOLOGY PROGRAM   (United States)

^d Southeast Cancer Control Consortium   (United States)

^e Metro Minnesota CCOP   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NAPROXEN; PLACEBO; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ADULT; ARTICLE; BONE PAIN; BREAST CANCER; CANCER CENTER; CANCER CHEMOTHERAPY; CANCER PATIENT; CLINICAL RESEARCH; COMMUNITY PROGRAM; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; INCIDENCE; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; ONCOLOGY; PAIN ASSESSMENT; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; TREATMENT OUTCOME; UNITED STATES; UNIVERSITY;

ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BORONIC ACIDS; FEMALE; HUMANS; MALE; MULTIPLE MYELOMA; PYRAZINES;

EID: 84863915110     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2011.37.8364     Document Type: Article

References (12)

1. Patterson K, Masuda SY, Brown SL: Safety profile of pegfilgrastim 9r-metHuG-CSF, in Morstyn G, Dexter TM, Foote MA (eds): Filgrastim (rmetHuG-CSF) in Clinical Practice. Totowa, NY, Humana Press, 1998, pp 583-601
2. Crawford J: Safety and efficacy of pegfilgrastim in patients receiving myelosuppressive chemotherapy. Pharmacotherapy 23:15S-19S, 2003 (supp)
3. Biganzoli L, Untch M, Skacel T, et al: Neulasta (pegfilgrastim): A once-per-cycle option for the management of chemotherapy-induced neutropenia. Semin Oncol 31:27-34, 2004 (suppl 8)
4. Crawford J: Once-per-cycle pegfilgrastim (Neulasta) for the management of chemotherapy-induced neutropenia. Semin Oncol 30:24-30, 2003 (suppl 13)
5. Citron ML, Berry DA, Cirrincione C, et al: Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: First report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741. J Clin Oncol 21:1431-1439, 2003 (Pubitemid 46594092)
6. Kummel S, Krocker J, Kohls A, et al: Randomised trial: Survival benefit and safety of adjuvant dose-dense chemotherapy for node-positive breast cancer. Br J Cancer 94:1237-1244, 2006
7. Kroschinsky F, Hölig K, Ehninger G: The role of pegfilgrastim in mobilization of hematopoietic stem cells. Transfus Apher Sci 38:237-244, 2008
8. Kubista E, Glaspy J, Holmes FA, et al: Bone pain associated with once-per-cycle pegfilgrastim is similar to daily filgrastim in patients with breast cancer. Clin Breast Cancer 3:391-398, 2003 (Pubitemid 36395548)
9. Heil G, Hoelzer D, Sanz MA, et al: A randomized, double-blind, placebo-controlled, phase III study of filgrastim in remission induction and consolidation therapy for adults with de novo acute myeloid leukemia: The International Acute Myeloid Leukemia Study Group. Blood 90:4710-4718, 1997 (Pubitemid 28007183)
10. Kirshner J, Hickock J, Hofman M: Pegfilgrastim-induced bone pain: Incidence, risk factors, and management in a community practice. Comm Onc 4:455-459, 2007
11. Cleeland CS, Mendoza TR, Wang XS, et al: Assessing symptom distress in cancer patients: The M.D. Anderson Symptom Inventory. Cancer 89:1634-1646, 2000
12. Hickok JT, Morrow GR, Roscoe JA, et al: Occurrence, severity, and longitudinal course of twelve common symptoms in 1129 consecutive patients during radiotherapy for cancer. J Pain Symptom Manage 30:433-442, 2005 (Pubitemid 41718963)