메뉴 건너뛰기




Volumn 109, Issue 28, 2012, Pages 11396-11401

Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYSTEINE; MALEIMIDE; PURINERGIC P2X1 RECEPTOR; RIBOSE; TETRAMETHYLRHODAMINE;

EID: 84863914041     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1118759109     Document Type: Article
Times cited : (60)

References (24)
  • 1
    • 67649639047 scopus 로고    scopus 로고
    • Signaling at purinergic P2X receptors
    • Surprenant A, North RA (2009) Signaling at purinergic P2X receptors. Annu Rev Physiol 71:333-359.
    • (2009) Annu Rev Physiol , vol.71 , pp. 333-359
    • Surprenant, A.1    North, R.A.2
  • 2
    • 67949117176 scopus 로고    scopus 로고
    • Crystal structure of the ATP-gated P2X(4) ion channel in the closed state
    • Kawate T, Michel JC, Birdsong WT, Gouaux E (2009) Crystal structure of the ATP-gated P2X(4) ion channel in the closed state. Nature 460:592-598.
    • (2009) Nature , vol.460 , pp. 592-598
    • Kawate, T.1    Michel, J.C.2    Birdsong, W.T.3    Gouaux, E.4
  • 5
    • 0034602169 scopus 로고    scopus 로고
    • Identification of amino acid residues contributing to the ATP-binding site of a purinergic P2X receptor
    • Jiang LH, Rassendren F, Surprenant A, North RA (2000) Identification of amino acid residues contributing to the ATP-binding site of a purinergic P2X receptor. J Biol Chem 275:34190-34196.
    • (2000) J Biol Chem , vol.275 , pp. 34190-34196
    • Jiang, L.H.1    Rassendren, F.2    Surprenant, A.3    North, R.A.4
  • 6
    • 1542275329 scopus 로고    scopus 로고
    • 1 receptors: Contribution of aromatic and basic amino acids revealed using mutagenesis and partial agonists
    • DOI 10.1074/jbc.M308964200
    • Roberts JA, Evans RJ (2004) ATP binding at human P2X1 receptors. Contribution of aromatic and basic amino acids revealed using mutagenesis and partial agonists. J Biol Chem 279:9043-9055. (Pubitemid 38295968)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.10 , pp. 9043-9055
    • Roberts, J.A.1    Evans, R.J.2
  • 7
    • 33846968794 scopus 로고    scopus 로고
    • Identification of an intersubunit cross-link between substituted cysteine residues located in the putative ATP binding site of the P2X1 receptor
    • Marquez-Klaka B, Rettinger J, Bhargava Y, Eisele T, Nicke A (2007) Identification of an intersubunit cross-link between substituted cysteine residues located in the putative ATP binding site of the P2X1 receptor. J Neurosci 27:1456-1466.
    • (2007) J Neurosci , vol.27 , pp. 1456-1466
    • Marquez-Klaka, B.1    Rettinger, J.2    Bhargava, Y.3    Eisele, T.4    Nicke, A.5
  • 8
    • 60549095934 scopus 로고    scopus 로고
    • Inter-subunit disulfide cross-linking in homomeric and heteromeric P2X receptors
    • Marquez-Klaka B, Rettinger J, Nicke A (2009) Inter-subunit disulfide cross-linking in homomeric and heteromeric P2X receptors. Eur Biophys J 38:329-338.
    • (2009) Eur Biophys J , vol.38 , pp. 329-338
    • Marquez-Klaka, B.1    Rettinger, J.2    Nicke, A.3
  • 9
    • 50649099067 scopus 로고    scopus 로고
    • Illuminating the structure and function of Cys-loop receptors
    • Pless SA, Lynch JW (2008) Illuminating the structure and function of Cys-loop receptors. Clin Exp Pharmacol Physiol 35:1137-1142.
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , pp. 1137-1142
    • Pless, S.A.1    Lynch, J.W.2
  • 11
    • 79959355099 scopus 로고    scopus 로고
    • Agonist trapped in ATP-binding sites of the P2X2 receptor
    • Jiang R, et al. (2011) Agonist trapped in ATP-binding sites of the P2X2 receptor. Proc Natl Acad Sci USA 108:9066-9071.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 9066-9071
    • Jiang, R.1
  • 12
    • 0037095757 scopus 로고    scopus 로고
    • 2 Purinoceptor
    • Clyne JD, Wang LF, Hume RI (2002) Mutational analysis of the conserved cysteines of the rat P2X2 purinoceptor. J Neurosci 22:3873-3880. (Pubitemid 37465695)
    • (2002) Journal of Neuroscience , vol.22 , Issue.10 , pp. 3873-3880
    • Clyne, J.D.1    Wang, L.-F.2    Hume, R.I.3
  • 13
    • 0036154216 scopus 로고    scopus 로고
    • 1 receptor form disulfide bonds and are involved in receptor trafficking to the cell surface
    • DOI 10.1124/mol.61.2.303
    • Ennion SJ, Evans RJ (2002) Conserved cysteine residues in the extracellular loop of the human P2X(1) receptor form disulfide bonds and are involved in receptor trafficking to the cell surface. Mol Pharmacol 61:303-311. (Pubitemid 34112804)
    • (2002) Molecular Pharmacology , vol.61 , Issue.2 , pp. 303-311
    • Ennion, S.J.1    Evans, R.J.2
  • 14
    • 0037625979 scopus 로고    scopus 로고
    • 1 receptor at nanomolar ATP concentrations
    • DOI 10.1085/jgp.200208730
    • Rettinger J, Schmalzing G (2003) Activation and desensitization of the recombinant P2X1 receptor at nanomolar ATP concentrations. J Gen Physiol 121:451-461. (Pubitemid 36542777)
    • (2003) Journal of General Physiology , vol.121 , Issue.5 , pp. 451-461
    • Rettinger, J.1    Schmalzing, G.2
  • 15
    • 34247120710 scopus 로고    scopus 로고
    • Cysteine substitution mutants give structural insight and identify ATP binding and activation sites at P2X receptors
    • DOI 10.1523/JNEUROSCI.2310-06.2007
    • Roberts JA, Evans RJ (2007) Cysteine substitution mutants give structural insight and identify ATP binding and activation sites at P2X receptors. J Neurosci 27:4072-4082. (Pubitemid 46597149)
    • (2007) Journal of Neuroscience , vol.27 , Issue.15 , pp. 4072-4082
    • Roberts, J.A.1    Evans, R.J.2
  • 16
    • 36348952111 scopus 로고    scopus 로고
    • 308
    • DOI 10.1523/JNEUROSCI.4036-07.2007
    • Cao L, Young MT, Broomhead HE, Fountain SJ, North RA (2007) Thr339-to-serine substitution in rat P2X2 receptor second transmembrane domain causes constitutive opening and indicates a gating role for Lys308. J Neurosci 27:12916-12923. (Pubitemid 350159573)
    • (2007) Journal of Neuroscience , vol.27 , Issue.47 , pp. 12916-12923
    • Cao, L.1    Young, M.T.2    Broomhead, H.E.3    Fountain, S.J.4    North, R.A.5
  • 17
    • 80051696222 scopus 로고    scopus 로고
    • Cysteine scanning mutagenesis (residues Glu52-Gly96) of the human P2X1 receptor for ATP: Mapping agonist binding and channel gating
    • Allsopp RC, El Ajouz S, Schmid R, Evans RJ (2011) Cysteine scanning mutagenesis (residues Glu52-Gly96) of the human P2X1 receptor for ATP: Mapping agonist binding and channel gating. J Biol Chem 286:29207-29217.
    • (2011) J Biol Chem , vol.286 , pp. 29207-29217
    • Allsopp, R.C.1    El Ajouz, S.2    Schmid, R.3    Evans, R.J.4
  • 18
    • 84858665860 scopus 로고    scopus 로고
    • Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel
    • Roberts JA, et al. (2012) Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel. Proc Natl Acad Sci USA 109:4663-4667.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 4663-4667
    • Roberts, J.A.1
  • 19
    • 84860540831 scopus 로고    scopus 로고
    • Tightening of the ATP-binding sites induces the opening of P2X receptor channels
    • Jiang R, et al. (2012) Tightening of the ATP-binding sites induces the opening of P2X receptor channels. EMBO J 31:2134-2143.
    • (2012) EMBO J , vol.31 , pp. 2134-2143
    • Jiang, R.1
  • 20
    • 84860785529 scopus 로고    scopus 로고
    • Molecular mechanism of ATP binding and ion channel activation in P2X receptors
    • Hattori M, Gouaux E (2012) Molecular mechanism of ATP binding and ion channel activation in P2X receptors. Nature 485:207-212.
    • (2012) Nature , vol.485 , pp. 207-212
    • Hattori, M.1    Gouaux, E.2
  • 21
    • 41749101060 scopus 로고    scopus 로고
    • Agonist- and competitive antagonist-induced movement of loop 5 on the alpha subunit of the neuronal alpha4beta4 nicotinic acetylcholine receptor
    • DOI 10.1111/j.1471-4159.2007.05151.x
    • Mourot A, Bamberg E, Rettinger J (2008) Agonist- and competitive antagonist-induced movement of loop 5 on the alpha subunit of the neuronal alpha4beta4 nicotinic acetylcholine receptor. J Neurochem 105:413-424. (Pubitemid 351490017)
    • (2008) Journal of Neurochemistry , vol.105 , Issue.2 , pp. 413-424
    • Mourot, A.1    Bamberg, E.2    Rettinger, J.3
  • 22
    • 0027136282 scopus 로고
    • Comparative protein modelling by satisfaction of spatial restraints
    • DOI 10.1006/jmbi.1993.1626
    • Sali A, Blundell TL (1993) Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol 234:779-815. (Pubitemid 24007801)
    • (1993) Journal of Molecular Biology , vol.234 , Issue.3 , pp. 779-815
    • Sali, A.1    Blundell, T.L.2
  • 23
    • 0020997912 scopus 로고
    • Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features
    • Kabsch W, Sander C (1983) Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features. Biopolymers 22:2577-2637.
    • (1983) Biopolymers , vol.22 , pp. 2577-2637
    • Kabsch, W.1    Sander, C.2
  • 24
    • 76149120388 scopus 로고    scopus 로고
    • AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
    • Trott O, Olson AJ (2010) AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J Comput Chem 31:455-461.
    • (2010) J Comput Chem , vol.31 , pp. 455-461
    • Trott, O.1    Olson, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.