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Volumn 31, Issue 7, 2012, Pages 1205-1213

Cytotoxicity, apoptosis, cellular uptake, cell cycle distribution, and DNA-binding investigation of ruthenium complexes

Author keywords

[No Author keywords available]

Indexed keywords

DNA; RUTHENIUM COMPLEX;

EID: 84863894995     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2011.1490     Document Type: Article
Times cited : (11)

References (24)
  • 1
    • 62749102801 scopus 로고    scopus 로고
    • Synthesis and DNA-binding studies of two ruthenium(II) complexes of an intercalating ligand
    • Arockiasamy, D.L., Radhika, S., Parthasarathi, R., and Nair, B.N. (2009). Synthesis and DNA-binding studies of two ruthenium(II) complexes of an intercalating ligand. Eur J Med Chem 44, 2044-2051.
    • (2009) Eur. J. Med. Chem. , vol.44 , pp. 2044-2051
    • Arockiasamy, D.L.1    Radhika, S.2    Parthasarathi, R.3    Nair, B.N.4
  • 2
    • 0039129419 scopus 로고
    • Photoactivated stereospecific cleavage of double-helical DNA by cobalt(III) complexes
    • Barton, J.K., and Raphael, A.L. (1984). Photoactivated stereospecific cleavage of double-helical DNA by cobalt(III) complexes. J Am Chem Soc 106, 2466-2468.
    • (1984) J. Am. Chem. Soc. , vol.106 , pp. 2466-2468
    • Barton, J.K.1    Raphael, A.L.2
  • 3
    • 0024804717 scopus 로고
    • Voltammetric studies of the interaction of metal chelates with DNA. 2. Tris-chelated complexes of cobalt(III) and iron(II) with 1,10-phenanthroline and 2,2'-bipyridine
    • Carter, M.T., Rodriguez, M., and Bard, A. (1989). Voltammetric studies of the interaction of metal chelates with DNA. 2. Tris-chelated complexes of cobalt(III) and iron(II) with 1,10-phenanthroline and 2,2'-bipyridine. J Am Chem Soc 111, 8901-8911.
    • (1989) J. Am. Chem. Soc. , vol.111 , pp. 8901-8911
    • Carter, M.T.1    Rodriguez, M.2    Bard, A.3
  • 4
    • 33646923190 scopus 로고    scopus 로고
    • A new family of mono- and dicarboxylic ruthenium complexes [Ru(DIP) 2(L2)] 2 + (DIP = 4,7-diphenyl-1,10-phenanthroline): Syn thesis, solution behavior, and X-ray molecular structure of trans-[Ru(DIP)2(MeOH)2][OTf]2
    • Caspar, R., Cordier, C., Waern, J.B., Guyard-Duhayon, C., Gruselle, M., Floch, P.L., and Amouri, H. (2006). A new family of mono- and dicarboxylic ruthenium complexes [Ru(DIP)2(L2)]2 + (DIP = 4,7-diphenyl-1,10-phenanthroline): Synthesis, solution behavior, and X-ray molecular structure of trans-[Ru(DIP)2(MeOH)2][OTf]2. Inorg Chem 45, 4071-4078.
    • (2006) Inorg. Chem. , vol.45 , pp. 4071-4078
    • Caspar, R.1    Cordier, C.2    Waern, J.B.3    Guyard-Duhayon, C.4    Gruselle, M.5    Floch, P.L.6    Amouri, H.7
  • 5
    • 55849149070 scopus 로고    scopus 로고
    • Mechanism of cellular uptake of a ruthenium polypyridyl complex
    • Cindy, A., and Barton, J.K. (2008). Mechanism of cellular uptake of a ruthenium polypyridyl complex. Biochemistry 47, 11711-11716.
    • (2008) Biochemistry , vol.47 , pp. 11711-11716
    • Cindy, A.1    Barton, J.K.2
  • 7
    • 33747072340 scopus 로고    scopus 로고
    • DNA interactions of a functionalized ruthenium(II) mixed-polypyridyl complex [Ru(bpy)2ppd]2 +
    • Gao, F., Chao, H., Zhou, F., Yuan, Y.X., Peng, B., and Ji, L.N. (2006). DNA interactions of a functionalized ruthenium(II) mixed-polypyridyl complex [Ru(bpy)2ppd]2 + . J Inorg Biochem 100, 1487-1494.
    • (2006) J. Inorg. Biochem. , vol.100 , pp. 1487-1494
    • Gao, F.1    Chao, H.2    Zhou, F.3    Yuan, Y.X.4    Peng, B.5    Ji, L.N.6
  • 8
    • 79958295514 scopus 로고    scopus 로고
    • Syn thesis, cellular uptake, apopotosis, cytotoxicity, interaction with DNA and antioxidant activity of ruthenium(II) complexes
    • Huang, H.L., Li, Z.Z., Liang, Z.H., and Liu, Y.J. (2011). Synthesis, cellular uptake, apopotosis, cytotoxicity, interaction with DNA and antioxidant activity of ruthenium(II) complexes. Eur J Med Chem 46, 3282-3290.
    • (2011) Eur. J. Med. Chem. , vol.46 , pp. 3282-3290
    • Huang, H.L.1    Li, Z.Z.2    Liang, Z.H.3    Liu, Y.J.4
  • 9
    • 38149074181 scopus 로고    scopus 로고
    • Syn thesis, antitumor activity and structure-activity relationships of a series of Ru(II) complexes
    • Liu, J., Zheng, W.J., Shi, S., Tan, C.P., Chen, J.C., Zheng, K.C., and Ji, L.N. (2008). Synthesis, antitumor activity and structure-activity relationships of a series of Ru(II) complexes. J Inorg Biochem 102, 193-202.
    • (2008) J. Inorg. Biochem. , vol.102 , pp. 193-202
    • Liu, J.1    Zheng, W.J.2    Shi, S.3    Tan, C.P.4    Chen, J.C.5    Zheng, K.C.6    Ji, L.N.7
  • 10
    • 0000727802 scopus 로고    scopus 로고
    • Polypyridyl ruthenium complexes containing intramolecular hydrogen-bond ligand: Syn thesis, characterization and DNA-binding properties
    • Liu, J.G., Ye, B.H., Li, H., Zhen, Q.X., Ji, L.N., and Fu, Y.H. (1999). Polypyridyl ruthenium complexes containing intramolecular hydrogen-bond ligand: Synthesis, characterization and DNA-binding properties. J Inorg Biochem 76, 265-271.
    • (1999) J. Inorg. Biochem. , vol.76 , pp. 265-271
    • Liu, J.G.1    Ye, B.H.2    Li, H.3    Zhen, Q.X.4    Ji, L.N.5    Fu, Y.H.6
  • 11
    • 69749092802 scopus 로고    scopus 로고
    • Effect of substituents on DNA-binding behaviors of ruthenium(II) complexes: [Ru(dmb) 2(dtmi)]2 + and [Ru(dmb) 2(dtni)]2
    • Liu, Y., Liu, Y.J., Yao, J.H., Mei, W.J., and Wu, F.H. (2009). Effect of substituents on DNA-binding behaviors of ruthenium(II) complexes: [Ru(dmb)2(dtmi)]2 + and [Ru(dmb)2(dtni)]2 +. J Coord Chem 62, 1701-1708.
    • (2009) J. Coord Chem. , vol.62 , pp. 1701-1708
    • Liu, Y.1    Liu, Y.J.2    Yao, J.H.3    Mei, W.J.4    Wu, F.H.5
  • 12
    • 80053467946 scopus 로고    scopus 로고
    • Ruthenium(II) polypyridyl complexes: Synthesis and studies of DNA-binding, photocleavage, cytotoxicity, apoptosis, cellular uptake and antioxidant activity
    • Liu, Y.J., Liang, Z.H., Li, Z.Z., and Huang, H.L. (2011). Ruthenium(II) polypyridyl complexes: Synthesis and studies of DNA-binding, photocleavage, cytotoxicity, apoptosis, cellular uptake and antioxidant activity, DNA Cell Biol 30, 829-838.
    • (2011) DNA Cell Biol. , vol.30 , pp. 829-838
    • Liu, Y.J.1    Liang, Z.H.2    Li, Z.Z.3    Huang, H.L.4
  • 13
    • 77954349732 scopus 로고    scopus 로고
    • Synthesis of ruthenium(II) complexes and characterization of their cytotoxicity in vitro, apoptosis, DNA-binding and antioxidant activity
    • Liu, Y.J., Zeng, C.H., Liang, Z.H., Yao, J.H., Huang, H.J., Li, Z.Z., and Wu, F.H. (2010). Synthesis of ruthenium(II) complexes and characterization of their cytotoxicity in vitro, apoptosis, DNA-binding and antioxidant activity. Eur J Med Chem 45, 3087-3095.
    • (2010) Eur. J. Med. Chem. , vol.45 , pp. 3087-3095
    • Liu, Y.J.1    Zeng, C.H.2    Liang, Z.H.3    Yao, J.H.4    Huang, H.J.5    Li, Z.Z.6    Wu, F.H.7
  • 14
    • 38849123731 scopus 로고    scopus 로고
    • Luminescent biological probes derived from ruthenium(II) estradiol polypyridine complexes
    • Lo, K.K., Lee, T.K., Lau, J.S., Poon, W.L., and Cheng, S.H. (2008). Luminescent biological probes derived from ruthenium(II) estradiol polypyridine complexes. Inorg Chem 47, 200-208.
    • (2008) Inorg. Chem. , vol.47 , pp. 200-208
    • Lo, K.K.1    Lee, T.K.2    Lau, J.S.3    Poon, W.L.4    Cheng, S.H.5
  • 15
    • 85010439719 scopus 로고
    • A procedure for the isolation of deoxyribonucleic acid from micro-organisms
    • Marmur, J. (1961). A procedure for the isolation of deoxyribonucleic acid from micro-organisms. J Mol Biol 3, 208-218.
    • (1961) J. Mol. Biol. , vol.3 , pp. 208-218
    • Marmur, J.1
  • 16
    • 0021061819 scopus 로고
    • Utilization of purified human monocytes in the agarose droplet assay for measuring migration inhibitory factors
    • Mosmann, T. (1983). Utilization of purified human monocytes in the agarose droplet assay for measuring migration inhibitory factors. J Immunol Methods 65, 55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 17
    • 33947455249 scopus 로고
    • A further examination of the molecular weight and size of desoxypentose nucleic acid
    • Reichmann, M.E., Rice, S.A., Thomas, C.A., and Doty, P. (1954). A further examination of the molecular weight and size of desoxypentose nucleic acid. J Am Chem Soc 76, 3047-3053.
    • (1954) J. Am. Chem. Soc. , vol.76 , pp. 3047-3053
    • Reichmann, M.E.1    Rice, S.A.2    Thomas, C.A.3    Doty, P.4
  • 18
    • 34447559793 scopus 로고    scopus 로고
    • Influence of the polypyridyl (pp) ligand size on the DNA binding properties, cytotoxicity and cellular uptake of organoruthenium(II) complexes of the type [(Z6-C6Me6)Ru(L)(pp)]n +[L = Cl, n = 1; L = (NH2)2CS, n = 2]
    • Schäfer, S., Ott, I., Gust, R., and Sheldrick, W.S. (2007). Influence of the polypyridyl (pp) ligand size on the DNA binding properties, cytotoxicity and cellular uptake of organoruthenium(II) complexes of the type [(Z6-C6Me6)Ru(L)(pp)]n +[L = Cl, n = 1; L = (NH2)2CS, n = 2]. Eur J Inorg Chem 2007, 3034-3046.
    • (2007) Eur. J. Inorg. Chem. 2007 , pp. 3034-3046
    • Schäfer, S.1    Ott, I.2    Gust, R.3    Sheldrick, W.S.4
  • 20
    • 0041152495 scopus 로고
    • Mixed phosphine 2,2'-bipyridine complexes of ruthenium
    • Sullivan, B.P., Salmon, D.J., and Meyer, T.J. (1978). Mixed phosphine 2,2'-bipyridine complexes of ruthenium. Inorg Chem 17, 3334-3341.
    • (1978) Inorg. Chem. , vol.17 , pp. 3334-3341
    • Sullivan, B.P.1    Salmon, D.J.2    Meyer, T.J.3
  • 21
    • 38949106943 scopus 로고    scopus 로고
    • Study on the interaction mechanism between DNA and the main active components in Scutellaria baicalensis Georgi
    • Sun, Y.T., Bi, S.Y., Song, D.Q., Qiao, C.Y., Mu, D., and Zhang, H.Q. (2008). Study on the interaction mechanism between DNA and the main active components in Scutellaria baicalensis Georgi. Sens. Actuators B 129, 799-810.
    • (2008) Sens. Actuators B , vol.129 , pp. 799-810
    • Sun, Y.T.1    Bi, S.Y.2    Song, D.Q.3    Qiao, C.Y.4    Mu, D.5    Zhang, H.Q.6
  • 22
    • 69349083590 scopus 로고    scopus 로고
    • In vitro study on DNA binding of ruthenium complexes with polypyridyl ligands
    • Tan, L.F., Shen, J.L., Chen, X.J., and Liang, X.L. (2009). In vitro study on DNA binding of ruthenium complexes with polypyridyl ligands. DNA Cell Biol 28, 461-468.
    • (2009) DNA Cell Biol. , vol.28 , pp. 461-468
    • Tan, L.F.1    Shen, J.L.2    Chen, X.J.3    Liang, X.L.4
  • 23
    • 0345118066 scopus 로고    scopus 로고
    • Effects of the substitution positions of Br group in intercalative ligand on the DNA-binding behaviors of Ru(II) polypyridyl complexes
    • Xu, H., Zheng, K.C., Lin, L.J., Li, H., Gao, Y., and Ji, L.N. (2004). Effects of the substitution positions of Br group in intercalative ligand on the DNA-binding behaviors of Ru(II) polypyridyl complexes. J Inorg Biochem 98, 87-97.
    • (2004) J. Inorg. Biochem. , vol.98 , pp. 87-97
    • Xu, H.1    Zheng, K.C.2    Lin, L.J.3    Li, H.4    Gao, Y.5    Ji, L.N.6
  • 24
    • 0001329372 scopus 로고
    • Synthesis and properties of diaminosubstituted dipyrido[3,2-A:2',3'-c] phenazine
    • Yamada, M., Tanaka, Y., Yoshimoto, Y., Kuroda, S., and Shimao, I. (1992). Synthesis and properties of diaminosubstituted dipyrido[3,2-a:2',3'-c] phenazine. Bull Chem Soc Jpn 65, 1006-1011.
    • (1992) Bull. Chem. Soc. Jpn. , vol.65 , pp. 1006-1011
    • Yamada, M.1    Tanaka, Y.2    Yoshimoto, Y.3    Kuroda, S.4    Shimao, I.5


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