Sodium hyaluronate as a drug-release system for VEGF 165 improves graft revascularization in anterior cruciate ligament reconstruction in a rabbit model

Experimental and Therapeutic Medicine

Volumn 4, Issue 3, 2012, Pages 430-434

  Chen, Jiarong ^a   Yang, Liu ^a   Guo, Lin ^a   Duan, Xiaojun ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Allograft; Anterior cruciate ligament; Revascularization; Sodium hyaluronate; Vascular endothelial growth factor

Indexed keywords

HYALURONIC ACID; PHOSPHATE BUFFERED SALINE; VASCULOTROPIN 165;

ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; ARTICLE; BIOMECHANICS; BONE PATELLAR TENDON BONE GRAFT; CONTROLLED STUDY; DRUG FORMULATION; DRUG RELEASE; EXPERIMENTAL RABBIT; FEMALE; GRAFT REVASCULARIZATION; NONHUMAN; REVASCULARIZATION; RIGIDITY; SPECTROPHOTOMETRY; STEADY STATE;

EID: 84863886082     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2012.629     Document Type: Article

References (20)

1. Arnoczky SP, Warren RF and Ashlock MA: Replacement of the anterior cruciate ligament using a patellar tendon allograft. An experimental study. J Bone Joint Surg Am 68: 376-385, 1986.
2. Bernatchez PN, Soker S and Sirois MG: Vascular endothelial growth factor effect on endothelial cell proliferation, migration, and platelet-activating factor synthesis is Flk-1-dependent. J Biol Chem 274: 31047-31054, 1999.
3. Chandrashekar L: Reply: hyaluronic acid: a unique topical vehicle for the localized delivery of drugs to the skin. J Eur Acad Dermatol Venereol 20: 1348-1349, 2006.
4. Delay BS, McGrath BE and Mindell ER: Observations on a retrieved patellar tendon autograft used to reconstruct the anterior cruciate ligament. A case report. J Bone Joint Surg Am 84: 1433-1438, 2002.
5. Dodge-Khatami A, Backer CL, Holinger LD, Mavroudis C, Cook KE and Crawford SE: Healing of a free tracheal autograft is enhanced by topical vascular endothelial growth factor in an experimental rabbit model. J Thorac Cardiovasc Surg 122: 554-561, 2001.
6. Guo L, Yang L, Duan XJ, et al: Second-look arthroscopy study after anterior cruciate ligament reconstruction: effect of residual anterior cruciate ligament tissue upon accelerating revascularization of allologous bone-patellar tendon-bone grafting. Zhonghua Yi Xue Za Zhi 89: 2030-2033, 2009 (In Chinese).
7. Kelly RM, Meyer JD, Matsuura JE, et al: In vitro release kinetics of gentamycin from a sodium hyaluronate gel delivery system suitable for the treatment of peripheral vestibular disease. Drug Dev Ind Pharm 25: 15-20, 1999.
8. Spitzer MS, Yoeruek E, Kaczmarek RT, et al: Sodium hyaluronate gels as a drug-release system for corticosteroids: release kinetics and antiproliferative potential for glaucoma surgery. Acta Ophthalmol 86: 842-848, 2008.
9. Matsumoto Y, Yamamoto I, Watanabe Y and Matsumoto M: Enhancing effect of viscous sodium hyaluronate solution on the rectal absorption of morphine. Biol Pharm Bull 18: 1744-1749, 1995.
10. Tan H, Yang B, Duan X, et al: The promotion of the vascularization of decalcified bone matrix in vivo by rabbit bone marrow mononuclear cell-derived endothelial cells. Biomaterials 30: 3560-3566, 2009.
11. Munaut C, Noel A, Hougrand O, Foidart JM, Boniver J and Deprez M: Vascular endothelial growth factor expression correlates with matrix metalloproteinases MT1-MMP, MMP-2 and MMP-9 in human glioblastomas. Int J Cancer 106: 848-855, 2003.
12. Scheffer SU, Unterhauser FN and Weiler A: Graft remodeling and ligamentization after cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 16: 834-842, 2008.
13. Shino K, Kawasaki T, Hirose H, Gotoh I, Inoue M and Ono K: Replacement of the anterior cruciate ligament by an allogeneic tendon graft. An experimental study in the dog. J Bone Joint Surg Br 66: 672-681, 1984.
14. Surendrakumar K, Martyn GP, Hodgers EC, Jansen M and Blair JA: Sustained release of insulin from sodium hyaluronate based dry powder formulations after pulmonary delivery to beagle dogs. J Control Release 91: 385-394, 2003.
15. Wei X, Mao Z, Hou Y, et al: Local administration of TGFbeta-1/ VEGF165 gene-transduced bone mesenchymal stem cells for Achilles allograft replacement of the anterior cruciate ligament in rabbits. Biochem Biophys Res Commun 406: 204-210, 2011.
16. Yoshikawa T, Tohyama H, Katsura T, et al: Effects of local administration of vascular endothelial growth factor on mechanical characteristics of the semitendinosus tendon graft after anterior cruciate ligament reconstruction in sheep. Am J Sports Med 34: 1918-1925, 2006.
17. Pattison JE, Hugtenburg RP and Green S: Enhancement of natural background gamma-radiation dose around uranium microparticles in the human body. J R Soc Interface 7: 603-611, 2010.
18. Pinkowski JL, Reiman PR and Chen SL: Human lymphocyte reaction to freeze-dried allograft and xenograft ligamentous tissue. Am J Sports Med 17: 595-600, 1989.
19. Pinkowski JL, Rodrigo JJ, Sharkey NA and Vasseur PB: Immune response to nonspecific and altered tissue antigens in soft tissue allografts. Clin Orthop Relat Res 326: 80-85, 1996.
20. Reikeras O, Sigurdsen UW and Shegarf H: Impact of freezing on immunology and incorporation of bone allograft. J Orthop Res 28: 1215-1219, 2010.