Silencing of FABP3 promotes apoptosis and induces mitochondrion impairment in embryonic carcinoma cells

Journal of Bioenergetics and Biomembranes

Volumn 44, Issue 3, 2012, Pages 317-323

  Shen, Ya Hui ^a   Song, Gui Xian ^a   Liu, Yao Qiu ^a   Sun, Wei ^a   Zhou, Li Juan ^a   Liu, Hai Lang ^a   Yang, Rong ^a   Sheng, Yan Hui ^a   Qian, Ling Mei ^a   Kong, Xiang Qing ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Congenital heart disease; FABP3; Mitochondria; RNA interference

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARRIER PROTEIN; DIMETHYL SULFOXIDE; FATTY ACID BINDING PROTEIN 3; MITOCHONDRIAL DNA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; DOWN REGULATION; EMBRYONAL CARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RNA INTERFERENCE;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; DNA, MITOCHONDRIAL; EMBRYONAL CARCINOMA STEM CELLS; FATTY ACID-BINDING PROTEINS; GENE DOSAGE; GENE KNOCKDOWN TECHNIQUES; MICE; MICROSCOPY, ELECTRON; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84863877663     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-012-9439-y     Document Type: Article

References (27)

1. Aagaard L, Rossi JJ (2007) RNAi therapeutics: principles, prospects and challenges. Adv Drug Deliv Rev 59:75-86 (Pubitemid 46770900)
2. Beal MF (2003) Bioenergetic approaches for neuroprotection in Parkinson's disease. Ann Neurol 53(Suppl 3):S39-S47, S47-S48
3. Bruneau BG, Nemer G, Schmitt JP, Charron F, Robitaille L, Caron S, Conner DA, Gessler M, Nemer M, Seidman CE, Seidman JG (2001) A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell 106:709-721 (Pubitemid 32900662)
4. Crow MT, Mani K, Nam YJ, Kitsis RN (2004) The mitochondrial death pathway and cardiac myocyte apoptosis. Circ Res 95:957-970 (Pubitemid 39532326)
5. Fiorina P, Corradi D, Pinelli S, Maestri R, Lagrasta C, Buscaglia M, Davalli A, Folli F, Astorri E (2004) Apoptotic/mitogenic pathways during human heart development. Int J Cardiol 96:409-417 (Pubitemid 39099504)
6. Green DR, Reed JC (1998) Mitochondria and apoptosis. Science 281:1309-1312 (Pubitemid 28406816)
7. Grepin C, Nemer G, Nemer M (1997) Enhanced cardiogenesis in embryonic stem cells overexpressing the GATA-4 transcription factor. Development 124:2387-2395 (Pubitemid 27309738)
8. Hoffman JI (1990) Congenital heart disease: incidence and inheritance. Pediatr Clin North Am 37:25-43
9. Kaaman M, SparksLM, van Harmelen V, Smith SR, Sjolin E, Dahlman I, Arner P (2007) Strong association between mitochondrial DNA copy number and lipogenesis in human white adipose tissue. Diabetologia 50:2526-2533 (Pubitemid 350060639)
10. Legros F, Lombes A, Frachon P, Rojo M (2002) Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. Mol Biol Cell 13:4343-4354 (Pubitemid 35471190)
11. Lints TJ, Parsons LM, Hartley L, Lyons I, Harvey RP (1993) Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 119:419-431 (Pubitemid 23293185)
12. Mannella CA (2006) Structure and dynamics of the mitochondrial inner membrane cristae. Biochim Biophys Acta 1763:542-548
13. Maxwell DP, Wang Y, McIntosh L (1999) The alternative oxidase lowers mitochondrial reactive oxygen production in plant cells. Proc Natl Acad Sci USA 96:8271-8276 (Pubitemid 29328444)
14. McCann CJ, Glover BM, Menown IB, Moore MJ, McEneny J, Owens CG, Smith B, Sharpe PC, Young IS, Adgey JA (2008) Novel biomarkers in early diagnosis of acute myocardial infarction compared with cardiac troponin T. Eur Heart J 29:2843-2850
15. Moller JH, Allen HD, Clark EB, Dajani AS, Golden A, Hayman LL, Lauer RM, Marmer EL, McAnulty JH, Oparil S et al (1993) Report of the task force on children and youth. American heart association. Circulation 88:2479-2486
16. Nemer M (2008) Genetic insights into normal and abnormal heart development. Cardiovasc Pathol 17:48-54
17. Robin ED, Wong R (1988) Mitochondrial DNA molecules and virtual number of mitochondria per cell in mammalian cells. J Cell Physiol 136:507-513
18. Sands AJ, Casey FA, Craig BG, Dornan JC, Rogers J, Mulholland HC (1999) Incidence and risk factors for ventricular septal defect in "low risk" neonates. Arch Dis Child Fetal Neonatal Ed 81:F61-F63 (Pubitemid 29307432)
19. Srivastava D, Olson EN (2000) A genetic blueprint for cardiac development. Nature 407:221-226
20. Tang MK, Kindler PM, Cai DQ, Chow PH, Li M, Lee KK (2004) Heart-type fatty acid binding proteins are upregulated during terminal differentiation of mouse cardiomyocytes, as revealed by proteomic analysis. Cell Tissue Res 316:339-347 (Pubitemid 38824000)
21. van der Heyden MA, Defize LH (2003) Twenty one years of P19 cells: what an embryonal carcinoma cell line taught us about cardiomyocyte differentiation. Cardiovasc Res 58:292-302
22. van der Heyden MA, van Kempen MJ, Tsuji Y, Rook MB, Jongsma HJ, Opthof T (2003) P19 embryonal carcinoma cells: a suitable model system for cardiac electrophysiological differentiation at the molecular and functional level. Cardiovasc Res 58:410-422 (Pubitemid 36570399)
23. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C (1995a) A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J Immunol Methods 184:39-51
24. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C (1995b) A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J Immunol Methods 184:39-51
25. Watt AJ, Battle MA, Li J, Duncan SA (2004) GATA4 is essential for formation of the proepicardium and regulates cardiogenesis. Proc Natl Acad Sci USA 101:12573-12578 (Pubitemid 39122065)
26. Zhang H, Zhou L, Yang R, Sheng Y, Sun W, Kong X, Cao K (2006) Identification of differentially expressed genes in human heart with ventricular septal defect using suppression subtractive hybridization. Biochem Biophys Res Commun 342:135-144 (Pubitemid 43247370)
27. Zhu C, Hu DL, Liu YQ, Zhang QJ, Chen FK, Kong XQ, Cao KJ, Zhang JS, Qian LM (2011) Fabp3 inhibits proliferation and promotes apoptosis of embryonic myocardial cells. Cell Biochem Biophys 60:259-266