HOG MAP kinase regulation of alternariol biosynthesis in Alternaria alternata is important for substrate colonization

International Journal of Food Microbiology

Volumn 157, Issue 3, 2012, Pages 353-359

  Graf, Eva ^a   Schmidt Heydt, Markus ^a   Geisen, Rolf ^a  

^a FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

Author keywords

Alternaria alternata; Alternariol; Colonization; HOG pathway; Osmotic stress

Indexed keywords

ALTERNARIOL; GLYCEROL; HIGH OSMOLARITY GLYCEROL; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ALTERNARIA ALTERNATA; ARTICLE; BIOSYNTHESIS; CEREAL; ENZYME REGULATION; FUNGAL COLONIZATION; GENE CONTROL; GENE INACTIVATION; NONHUMAN; OSMOTIC STRESS; PHOSPHORYLATION; PROTOPLAST; SIGNAL TRANSDUCTION; SUBSTRATE INDUCED RESPIRATION; TOMATO;

ALTERNARIA; FRUIT; LACTONES; MITOGEN-ACTIVATED PROTEIN KINASES; MYCOTOXINS; OSMOLAR CONCENTRATION; PHOSPHORYLATION; VEGETABLES; WATER;

ALTERNARIA; ALTERNARIA ALTERNATA; FUNGI; LYCOPERSICON ESCULENTUM;

EID: 84863874641     PISSN: 01681605     EISSN: 18793460     Source Type: Journal    
DOI: 10.1016/j.ijfoodmicro.2012.06.004     Document Type: Article

References (35)

1. Andersen B., Smedsgaard J., Jorring I., Skouboe P., Pedersen L.H. Real-time PCR quantification of the AM-toxin gene and HPLC qualification of toxigenic metabolites from Alternaria species from apples. International Journal of Food Microbiology 2006, 111:105-111.
2. Brugger E.M., Wagner J., Schumacher D.M., Koch K., Podlech J., Metzler M., Lehmann L. Mutagenicity of the mycotoxin alternariol in cultured mammalian cells. Toxicology Letters 2006, 164:221-230.
3. Burkhardt B., Wittenauer J., Pfeiffer E., Schauer U.M., Metzler M. Oxidative metabolism of the mycotoxins alternariol and alternariol-9-methyl ether in precision-cut rat liver slices in vitro. Molecular Nutrition & Food Research 2011, 55:1079-1086.
4. Cairns-Fuller V., Aldred D., Magan N. Water, temperature and gas composition interactions affect growth and ochratoxin A production by isolates of Penicillium verrucosum on wheat grain. Journal of Applied Microbiology 2005, 99:1215-1221.
5. Feng F., Qiu D.W., Jiang L.H. Isolation of cDNA sequences encoding the MAP kinase HOG1 and the MAP kinase kinase PBS2 genes of the fungus Alternaria tenuissima through a genetic approach. Journal of Microbiological Methods 2007, 69:188-196.
6. Gustin M.C., Albertyn J., Alexander M., Davenport K. MAP kinase pathways in the yeast Saccharomyces cerevisiae. Microbiology and Molecular Biology Review 1998, 62:1264-1300.
7. Hohmann S. Integrative analysis of yeast osmoregulation. Stress in Yeasts and Filamentous Fungi 2008, 109-128. Elsevier, Amsterdam. S. Avery, M. Stratford, P. van West (Eds.).
8. Kohut G., Ádám A., Fazekas B., Hornok L. N-starvation stress induced FUM gene expression and fumonisin production is mediated via the HOG-type MAPK pathway in Fusarium proliferatum. International Journal of Food Microbiology 2009, 130:65-69.
9. Leong S.L., Hocking A.D., Scott E.S. Effect of temperature and water activity on growth and ochratoxin A production by Australian Aspergillus carbonarius and A. niger isolates on a simulated grape juice medium. International Journal of Food Microbiology 2006, 110:209-216.
10. Lin C.H., Chung K.R. Specialized and shared functions of the histidine kinase- and HOG1 MAP kinase-mediated signaling pathways in Alternaria alternata, a filamentous fungal pathogen of citrus. Fungal Genetics and Biology 2010, 47:818-827.
11. Liu G., Qian Y., Zhang P., Dong Z., Shi Z., Zhen Y., Miao J., Xu Y. Relationships between Alternaria alternata and oesophageal cancer. International Agency for Research on Cancer 1991, 258-262.
12. Logrieco A., Moretti A., Solfrizzo M. Alternaria toxins and plant diseases: an overview of origin, occurrence and risks. World Mycotoxin Journal 2009, 2:129-140.
13. Magan N., Cayley G., Lacey J. Effect of water activity and temperature on mycotoxin production by Alternaria alternata in culture and on wheat grain. Applied and Environmental Microbiology 1984, 47:1113-1117.
14. Morris P.F., Connolly M.S., St Clair D.A. Genetic diversity of Alternaria alternata isolated from tomato in California assessed using RAPDs. Mycological Research 2000, 104:286-292.
15. Ochiai N., Tokai T., Nishiuchi T., Takahashi-Ando N., Fujimura M., Kimura M. Involvement of the osmosensor histidine kinase and osmotic stress-activated protein kinases in the regulation of secondary metabolism in Fusarium graminearum. Biochemical and Biophysical Research Communications 2007, 363:639-644.
16. Ochiai N., Tokai T., Takahashi-Ando N., Fujimura M., Kimura M. Genetically engineered Fusarium as a tool to evaluate the effects of environmental factors on initiation of trichothecene biosynthesis. FEMS Microbiology Letters 2007, 275:53-61.
17. Ostry V. Alternaria mycotoxins: an overview of chemical characterization, producers, toxicity, analysis and occurrence in foodstuffs. World Mycotoxin Journal 2008, 1:175-188.
18. Oviedo M.S., Ramirez M., Barros G., Chulze S. Impact of water activity and temperature on growth and alternariol and alternariol monomethyl ether production of Alternaria alternata isolated from soybean. Journal of Food Protection 2010, 73:336-343.
19. Patriarca A., Azcarate M.P., Terminiello L., Pinto V.F. Mycotoxin production by Alternaria strains isolated from Argentinean wheat. International Journal of Food Microbiology 2007, 119:219-222.
20. Pfeiffer E., Eschbach S., Metzler M. Alternaria toxins: DNA strand-breaking activity in mammalian cells in vitro. Mycotoxin Research 2007, 23:152-157.
21. Pose G., Patriarca A., Kyanko Y., Pardo A., Pinto V. Water activity and temperature effects on mycotoxin production by Alternaria alternata on a synthetic tomato medium. International Journal of Food Microbiology 2010, 142:348-353.
22. Punt P., Oliver R., Dingemanse U., Pouwels P., van der Hondal C. Transformation of Aspergillus based on the hygromycin B resistance marker from Escherichia coli. Gene 1987, 56:117-124.
23. Quinn J. Differences in stress responses between model and pathogenic fungi. Stress in Yeasts and Filamentous Fungi 2008, 67-85. Elsevier, Amsterdam. S. Avery, M. Stratford, P. van West (Eds.).
24. Sambrook J., Russel D.W. Molecular Cloning 2001, Cold Spring Harbour Laboratory Press, Cold Spring Harbour, NY. 3rd ed.
25. Sanzani S., Reverberi M., Punelli M., Ippolito A., Fanelli C. Study on the role of patulin on pathogenicity and virulence of Penicillium expansum. International Journal of Food Microbiology 2012, 153:323-331.
26. Schmidt-Heydt M., Graf E., Batzler J., Geisen R. The application of transcriptomics to understand the ecological reasons of ochratoxin a biosynthesis by Penicillium nordicum on sodium chloride rich dry cured foods. Trends in Food Science & Technology 2011, 22:39-48.
27. Schmidt-Heydt M., Graf E., Stoll D., Geisen R. The biosynthesis of ochratoxin A by Penicillium as one mechanism for adaptation to NaCl rich foods. Food Microbiology 2012, 29:233-241.
28. Somma S., Pose G., Pardo A., Mule G., Pinto V.F., Moretti A., Logrieco A.F. AFLP variability, toxin production, and pathogenicity of Alternaria species from Argentinean tomato fruits and puree. International Journal of Food Microbiology 2011, 145:145.
29. Stinson E.E. Mycotoxins - their biosynthesis in Alternaria. Journal of Food Protection 1985, 48:80-91.
30. Takano Y., Kikuchi T., Kubo Y., Hamer J.E., Mise K., Furusawa I. The Colletotrichum lagenarium MAP kinase gene CMK1 regulates diverse aspects of fungal pathogenesis. Molecular Plant-Microbe Interactions 2000, 13:374-383.
31. Tran-Dinh N., Hocking A. Isolation and characterization of polymorphic microsatellite markers for Alternaria alternata. Molecular Ecology Notes 2006, 6:405-407.
32. Tsuge T., Nishimura S., Kobayashi H. Efficient integrative transformation of the phytopathogenic fungus Alternaria alternata mediated by the repetitive rDNA sequences. Gene 1990, 90:207-214.
33. Zhang H., Murzello C., Sun Y., Kim M., Xie X., Jeter R., Paré P. Choline and osmotic stress tolerance induced in Arabidopsis by the soil microbe Bacillus subtilis (GB03). Journal of the American Chemical Society 2010, 23:1097-1104.
34. Zhang Y., Choi Y., Zou X., Xu J. The FvMK1 mitogen-activated protein kinase gene regulates conidiation, pathogenesis, and fumonisin production in Fusarium verticillioides. Fungal Genetics and Biology 2011, 48:71-79.
35. FDA last access 2012/03/09. http://www.fda.gov/food/foodsafety/retailfoodprotection/industryandregulatoryassistanceandtrainingresources/ucm113843.htm.