AFRICAN TRYPANOSOMIASIS;
BLOOD BRAIN BARRIER;
CENTRAL NERVOUS SYSTEM;
DISEASE SEVERITY;
DRUG BIOAVAILABILITY;
DRUG EFFICACY;
DRUG INDUSTRY;
DRUG SAFETY;
DRUG SOLUBILITY;
ENCEPHALITIS;
HUMAN;
MORBIDITY;
MORTALITY;
NONHUMAN;
REVIEW;
The human African trypanosomiasis control and surveillance programme of the World Health Organisation 2000-2009: the way forward
Simarro P.P., et al. The human African trypanosomiasis control and surveillance programme of the World Health Organisation 2000-2009: the way forward. PLoS Negl. Trop. Dis. 2011, 5:e1007.
Quantifying the level of under-detection of Trypanosome brucei rhodesiense sleeping sickness cases
Odiit M., et al. Quantifying the level of under-detection of Trypanosome brucei rhodesiense sleeping sickness cases. Trop. Med. Int. Health 2005, 10:840-849.
Intrathecal immune response pattern for improved diagnosis of central nervous system involvement in trypanosomiasis
Lejon V., et al. Intrathecal immune response pattern for improved diagnosis of central nervous system involvement in trypanosomiasis. J. Infect. Dis. 2003, 187:1475-1483.
Effectiveness of a 10-day melarsoprol schedule for the treatment of late-stage human African trypanosomiasis: confirmation from a multinational study (IMPAMEL II)
Schmid C., et al. Effectiveness of a 10-day melarsoprol schedule for the treatment of late-stage human African trypanosomiasis: confirmation from a multinational study (IMPAMEL II). J. Infect. Dis. 2005, 191:1922-1931.
Fexinidazole - a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness
Torreele E., et al. Fexinidazole - a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness. PLoS Negl. Trop. Dis. 2010, 4:e923.
SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis
Jacobs R.T., et al. SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis. PLoS Negl. Trop. Dis. 2011, 5:e1151.
Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis
Rodgers J., et al. Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis. PLoS Negl. Trop. Dis. 2011, 5:e1308.