Baseline characteristics and follow-up in patients with normal haemodynamics versus borderline mean pulmonary arterial pressure in systemic sclerosis: Results from the PHAROS registry

Annals of the Rheumatic Diseases

Volumn 71, Issue 8, 2012, Pages 1335-1342

  Bae, Sangmee ^a   Saggar, Rajeev ^b   Bolster, Marcy B ^c   Chung, Lorinda ^d   Csuka, Mary Ellen ^e   Derk, Chris ^f   Domsic, Robyn ^g   Fischer, Aryeh ^h   Frech, Tracy ⁱ   Goldberg, Avram ^j   Hinchcliff, Monique ^k   Hsu, Vivien ^l   Hummers, Laura ^m   Schiopu, Elena ⁿ   Mayes, Maureen D ^o   McLaughlin, Vallerie ⁿ   Molitor, Jerry ^p   Naz, Nausheen ^q   Furst, Daniel E ^a   Maranian, Paul ^a   Steen, Virginia ^r   Khanna, Dinesh ⁿ   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ST JOSEPH'S HOSPITAL AND MEDICAL CENTER   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d STANFORD UNIVERSITY   (United States)

^e MEDICAL COLLEGE OF WISCONSIN   (United States)

^f THOMAS JEFFERSON UNIVERSITY   (United States)

^g UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^h DEPARTMENT OF MEDICINE   (United States)

ⁱ UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^j LONG ISLAND JEWISH MEDICAL CENTER   (United States)

^k NORTHWESTERN UNIVERSITY   (United States)

^l UNIVERSITY OF MEDICINE AND DENTISTRY   (United States)

^m JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁿ UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^o UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^p UNIVERSITY OF MINNESOTA   (United States)

^q UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^r GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE COURSE; ECHOCARDIOGRAPHY; EXERCISE; FEMALE; FOLLOW UP; HEART CATHETERIZATION; HEART RIGHT VENTRICLE PRESSURE; HEMODYNAMICS; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; LONGITUDINAL STUDY; LUNG ARTERY PRESSURE; LUNG DISEASE; LUNG FIBROSIS; LUNG FUNCTION TEST; LUNG VASCULAR RESISTANCE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PULMONARY HYPERTENSION; REGISTER; SYSTEMIC SCLEROSIS; SYSTOLIC BLOOD PRESSURE;

BLOOD PRESSURE; CARDIAC CATHETERIZATION; FEMALE; FOLLOW-UP STUDIES; HEMODYNAMICS; HUMANS; HYPERTENSION, PULMONARY; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PULMONARY ARTERY; PULMONARY FIBROSIS; RESPIRATORY FUNCTION TESTS; SCLERODERMA, SYSTEMIC;

EID: 84863812040     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2011-200546     Document Type: Article

References (27)

1. Steen VD, Medsger TA. Changes in causes of death in systemic sclerosis, 1972-2002. Ann Rheum Dis 2007;66:940-4. (Pubitemid 46999798)
2. McLaughlin VV, Archer SL, Badesch DB, et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. Circulation 2009;119:2250-94.
3. Kovacs G, Berghold A, Scheidl S, et al. Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review. Eur Respir J 2009;34:888-94.
4. McLaughlin V, Humbert M, Coghlan G, et al. Pulmonary arterial hypertension: the most devastating vascular complication of systemic sclerosis. Rheumatology (Oxford) 2009;48 (Suppl 3):iii25-31.
5. Steen VD, Lucas M, Fertig N, et al. Pulmonary arterial hypertension and severe pulmonary fibrosis in systemic sclerosis patients with a nucleolar antibody. J Rheumatol 2007;34:2230-5. (Pubitemid 350076884)
6. Steen VD. The lung in systemic sclerosis. J Clin Rheumatol 2005;11:40-6. (Pubitemid 40223879)
7. Galiè N, Hoeper MM, Humbert M, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J 2009;30:2493-537.
8. Badesch DB, Champion HC, Sanchez MA, et al. Diagnosis and assessment of pulmonary arterial hypertension. J Am Coll Cardiol 2009;54 (Suppl 1):S55-66.
9. Hinchcliff M, Fischer A, Schiopu E, et al. Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma (PHAROS): baseline characteristics and description of study population. J Rheumatol 2011;38:2172-9.
10. Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 1980;23:581-90.
11. LeRoy EC, Black C, Fleischmajer R, et al. Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 1988;15:202-5. (Pubitemid 18073738)
12. Steen V, Chou M, Shanmugam V, et al. Exercise-induced pulmonary arterial hypertension in patients with systemic sclerosis. Chest 2008;134:146-51. (Pubitemid 352008776)
13. Saggar R, Khanna D, Furst DE, et al. Exercise-induced pulmonary hypertension associated with systemic sclerosis: four distinct entities. Arthritis Rheum 2010;62:3741-50.
14. Steen VD, Champion H. Is exercise-induced pulmonary hypertension ready for prime time in systemic sclerosis? Int J Clin Pract Suppl 2011 Jan;(169):1-3.
15. Steen V, Medsger TA Jr. Predictors of isolated pulmonary hypertension in patients with systemic sclerosis and limited cutaneous involvement. Arthritis Rheum 2003;48:516-22. (Pubitemid 36278021)
16. Chang B, Schachna L, White B, et al. Natural history of mild-moderate pulmonary hypertension and the risk factors for severe pulmonary hypertension in scleroderma. J Rheumatol 2006;33:269-74. (Pubitemid 43209302)
17. Cox SR, Walker JG, Coleman M, et al. Isolated pulmonary hypertension in scleroderma. Intern Med J 2005;35:28-33. (Pubitemid 40254764)
18. Plastiras SC, Karadimitrakis SP, Kampolis C, et al. Determinants of pulmonary arterial hypertension in scleroderma. Semin Arthritis Rheum 2007;36:392-6. (Pubitemid 46776817)
19. Mukerjee D, St George D, Knight C, et al. Echocardiography and pulmonary function as screening tests for pulmonary arterial hypertension in systemic sclerosis. Rheumatology (Oxford) 2004;43:461-6. (Pubitemid 38489363)
20. Stupi AM, Steen VD, Owens GR, et al. Pulmonary hypertension in the CREST syndrome variant of systemic sclerosis. Arthritis Rheum 1986;29:515-24. (Pubitemid 16118701)
21. Condliffe R, Kiely DG, Peacock AJ, et al. Connective tissue disease-associated pulmonary arterial hypertension in the modern treatment era. Am J Respir Crit Care Med 2009;179:151-7.
22. Mathai SC, Hummers LK, Champion HC, et al. Survival in pulmonary hypertension associated with the scleroderma spectrum of diseases: impact of interstitial lung disease. Arthritis Rheum 2009;60:569-77.
23. Kovacs G, Maier R, Aberer E, et al. Borderline pulmonary arterial pressure is associated with decreased exercise capacity in scleroderma. Am J Respir Crit Care Med 2009;180:881-6.
24. Reichenberger F, Voswinckel R, Schulz R, et al. Non-invasive detection of early pulmonary vascular dysfunction in scleroderma. Respir Med 2009;103:1713-18.
25. Alkotob ML, Soltani P, Sheatt MA, et al. Reduced exercise capacity and stress-induced pulmonary hypertension in patients with scleroderma. Chest 2006;130:176-81. (Pubitemid 44116857)
26. Collins N, Bastian B, Quiqueree L, et al. Abnormal pulmonary vascular responses in patients registered with a systemic autoimmunity database: Pulmonary Hypertension Assessment and Screening Evaluation using stress echocardiography (PHASE-I). Eur J Echocardiogr 2006;7:439-46. (Pubitemid 44645060)
27. Schreiber B, Valerio C, Handler C, et al. Predictors of progression to pulmonary hypertension in systemic sclerosis[Abstract]. Ann Rheum Dis 2011;70 (Suppl 3):168.