Lansoprazole inhibits nitric oxide and prostaglandin E 2 production in murine macrophage RAW 264.7 cells

Inflammation

Volumn 35, Issue 3, 2012, Pages 1062-1068

  Nakagawa, Shuji ^a   Arai, Yuji ^a   Kishida, Tsunao ^a   Hiraoka, Nobuyuki ^a   Tsuchida, Shinji ^a   Inoue, Hiroaki ^a   Sakai, Ryo ^a   Mazda, Osam ^a   Kubo, Toshikazu ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Lansoprazole; Macrophage; NADPH oxidase; Nitric oxide; Prostaglandin E 2

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CYCLOOXYGENASE 2; DIPHENYLIODONIUM SALT; INDUCIBLE NITRIC OXIDE SYNTHASE; LANSOPRAZOLE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; INFLAMMATION; INFLAMMATORY DISEASE; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN EXPRESSION;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; DINOPROSTONE; ENZYME INHIBITORS; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NADPH OXIDASE; NITRIC OXIDE; ONIUM COMPOUNDS; PROTON PUMPS; REACTIVE OXYGEN SPECIES;

MURINAE;

EID: 84863810033     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-011-9412-7     Document Type: Article

References (16)

1. Biswas, K., U. Bandyopadhyay, I. Chattopadhyay, A. Varadaraj, E. Ali, and R.K. Banerjee. 2003. A novel antioxidant and antiapoptotic role of omeprazole to block gastric ulcer through scavenging of hydroxyl radical. Journal of Biological Chemistry 278(13): 10993-11001. (Pubitemid 36792647)
2. Yoshida, N., T. Yoshikawa, Y. Tanaka, N. Fujita, K. Kassai, Y. Naito, and M. Kondo. 2000. A new mechanism for anti-inflammatory actions of proton pump inhibitors - inhibitory effects on neutrophil-endothelial cell interactions. Alimentary Pharmacology & Therapeutics 14(Suppl 1): 74-81. (Pubitemid 30199109)
3. Dickinson, J.B. 1994. Is omeprazole helpful in inflammatory bowel disease? Journal of Clinical Gastroenterology 18(4): 317-319. (Pubitemid 24160729)
4. Elliott, M.J., R.N. Maini, M. Feldmann, A. Long-Fox, P. Charles, H. Bijl, and J.N. Woody. 1994. Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis. Lancet 344(8930): 1125-1127. (Pubitemid 24317633)
5. Ikeda, U., and K. Shimada. 1999. Statins and monocytes. Lancet 353(9169): 2070.
6. Kim, J.K., S.M. Oh, H.S. Kwon, Y.S. Oh, S.S. Lim, and H.K. Shin. 2006. Anti-inflammatory effect of roasted licorice extracts on lipopolysaccharide- induced inflammatory responses in murine macrophages. Biochemical and Biophysical Research Communications 345(3): 1215-1223. (Pubitemid 44218790)
7. Sakao, K., K.A. Takahashi, O. Mazda, Y. Arai, H. Tonomura, A. Inoue, M. Saito, M. Fujioka, H. Takamiya, J. Imanishi, and T. Kubo. 2008. Enhanced expression of interleukin-6, matrix metalloproteinase- 13, and receptor activator of NF-kappaB ligand in cells derived from osteoarthritic subchondral bone. Journal of Orthopaedic Science 13(3): 202-210. (Pubitemid 351799216)
8. Li, J.M., N.P. Gall, D.J. Grieve, M. Chen, and A.M. Shah. 2002. Activation of NADPH oxidase during progression of cardiac hypertrophy to failure. Hypertension 40(4): 477-484.
9. Blandizzi, C., G. Natale, G. Gherardi, G. Lazzeri, C. Marveggio, R. Colucci, D. Carignani, and M. Del Tacca. 1999. Acid-independent gastroprotective effects of lansoprazole in experimental mucosal injury. Digestive Diseases and Sciences 44(10): 2039-2050. (Pubitemid 29510815)
10. Nakamura, M., M. Asada, K. Atsuda, H. Matsui, T. Watanabe, K. Higuchi, T. Arakawa, N. Hibi, and K. Tsuchimoto. 2005. Lansoprazole binding to the neutrophils in dextran sulfate sodium-induced rat colitis. Inflammopharmacology 13(1-3): 303-315. (Pubitemid 41607390)
11. Hinoki, A., K. Yoshimura, K. Fujita, M. Akita, R. Ikeda, M. Nagashima, M. Nomura, and A. Satomi. 2006. Suppression of proinflammatory cytokine production in macrophages by lansoprazole. Pediatric Surgery International 22(11): 915-923. (Pubitemid 44630525)
12. Harris, S.G., J. Padilla, L. Koumas, D. Ray, and R.P. Phipps. 2002. Prostaglandins as modulators of immunity. Trends in Immunology 23(3): 144-150. (Pubitemid 34178297)
13. Lee, T.Y., K.C. Lee, S.Y. Chen, and H.H. Chang. 2009. 6-Gingerol inhibits ROS and iNOS through the suppression of PKC-alpha and NF-kappaB pathways in lipopolysaccharide-stimulated mousemacrophages. Biochemical and Biophysical Research Communications 382(1): 134-139.
14. Adams, D.O., and T.A. Hamilton. 1984. The cell biology of macrophage activation. Annual Review of Immunology 2: 283-318.
15. Sarna, L.K., N. Wu, S.Y. Hwang, Y.L. Siow, and O. Karmin. 2010. Berberine inhibits NADPH oxidase mediated superoxide anion production in macrophages. Canadian Journal of Physiology and Pharmacology 88(3): 369-378.
16. Sadowska, A.M., B. Manuel-Y-Keenoy, and W.A. De Backer. 2007. Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: discordant in vitro and in vivo dose-effects: a review. Pulmonary Pharmacology and Therapeutics 20(1): 9-22. (Pubitemid 44648802)