Proteomics identification of annexin A2 as a key mediator in the metastasis and proangiogenesis of endometrial cells in human adenomyosis

Molecular and Cellular Proteomics

Volumn 11, Issue 7, 2012, Pages

  Zhou, Shengtao ^a   Yi, Tao ^a   Liu, Rui ^a   Bian, Ce ^a   Qi, Xiaorong ^a   He, Xiang ^a   Wang, Kui ^a   Li, Jingyi ^a   Zhao, Xia ^a   Huang, Canhua ^a   Wei, Yuquan ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; ESTROGEN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIPOCORTIN 2; T CELL FACTOR PROTEIN; VASCULOTROPIN A; ANXA2 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; TUMOR MARKER; TUMOR PROTEIN; VEGFA PROTEIN, HUMAN;

ADENOMYOMA; ADENOMYOSIS; ADULT; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER PATIENT; CARCINOGENESIS; CELL PROLIFERATION; CELL STRUCTURE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE MARKER; DISEASE SEVERITY; DYSMENORRHEA; ELECTROSPRAY MASS SPECTROMETRY; ENDOMETRIAL DISEASE; ENDOMETRIUM; ENDOMETRIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; FLOW CYTOMETRY; GENE CLUSTER; GENE EXPRESSION; GENE OVEREXPRESSION; GROWTH INHIBITION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERALGESIA; HYSTERECTOMY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MEDIATOR; METASTASIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TISSUE GROWTH; TISSUE SECTION; TUMOR XENOGRAFT; TWO DIMENSIONAL GEL ELECTROPHORESIS; UNINDEXED SEQUENCE; ANIMAL; ENDOMETRIOSIS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; MULTIGENE FAMILY; MYOMETRIUM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; UTERUS CANCER; VASCULARIZATION;

MUS MUSCULUS;

ADULT; ANIMALS; ANNEXIN A2; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOMETRIOSIS; ENDOMETRIUM; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MIDDLE AGED; MULTIGENE FAMILY; MYOMETRIUM; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; PROTEOMICS; TANDEM MASS SPECTROMETRY; TUMOR MARKERS, BIOLOGICAL; UTERINE NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84863793842     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M112.017988     Document Type: Article

References (44)

1. Ferenczy, A. (1998) Pathophysiology of adenomyosis. Hum. Reprod. Update 4, 312-322
2. Bergholt, T., Eriksen, L., Berendt, N., Jacobsen, M., and Hertz, J. B. (2001) Prevalence and risk factors of adenomyosis at hysterectomy. Hum. Reprod. 16, 2418-2421 (Pubitemid 33054148)
3. Williams, C. S., Zhang, B., Smith, J. J., Jayagopal, A., Barrett, C. W., Pino, C., Russ, P., Presley, S. H., Peng, D., Rosenblatt, D. O., Haselton, F. R., Yang, J. L., Washington, M. K., Chen, X., Eschrich, S., Yeatman, T. J., El-Rifai, W., Beauchamp, R. D., and Chang, M. S. (2011) BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma. J. Clin. Invest. 121, 4056-4069
4. Terao, M., Ishikawa, A., Nakahara, S., Kimura, A., Kato, A., Moriwaki, K., Kamada, Y., Murota, H., Taniguchi, N., Katayama, I., and Miyoshi, E. (2011) Enhanced epithelial-mesenchymal transition-like phenotype in N-acetylglucosaminyltransferase V transgenic mouse skin promotes wound healing. J. Biol. Chem. 286, 28303-28311
5. Cannito, S., Novo, E., di Bonzo, L. V., Busletta, C., Colombatto, S., and Parola, M. (2010) Epithelial-mesenchymal transition: From molecular mechanisms, redox regulation to implications in human health and disease. Antioxid. Redox. Signal. 12, 1383-1430
6. Scotti, S., Regidor, P. A., Schindler, A. E., and Winterhager, E. (2000) Reduced proliferation and cell adhesion in endometriosis. Mol. Hum. Reprod. 6, 610-617 (Pubitemid 30470092)
7. Zhang, H., Niu, Y., Feng, J., Guo, H., Ye, X., and Cui, H. (2006) Use of proteomic analysis of endometriosis to identify different protein expression in patients with endometriosis versus normal controls. Fertil. Steril. 86, 274-282 (Pubitemid 44118972)
8. Potente, M., Gerhardt, H., and Carmeliet, P. (2011) Basic and therapeutic aspects of angiogenesis. Cell 146, 873-887
9. Koh, Y. J., Kim, H. Z., Hwang, S. I., Lee, J. E., Oh, N., Jung, K., Kim, M., Kim, K. E., Kim, H., Lim, N. K., Jeon, C. J., Lee, G. M., Jeon, B. H., Nam, D. H., Sung, H. K., Nagy, A., Yoo, O. J., and Koh, G. Y. (2010) Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage. Cancer Cell 18, 171-184
10. Ota, H., Igarashi, S., and Tanaka, T. (1998) Morphometric evaluation of stromal vascularization in the endometrium in adenomyosis. Hum. Reprod. 13, 715-719 (Pubitemid 28171975)
11. Li, Z., Zhao, X., Bai, S., Wang, Z., Chen, L., Wei, Y., and Huang, C. (2008) Proteomics identification of cyclophilin A as a potential prognostic factor and therapeutic target in endometrial carcinoma. Mol. Cell. Proteomics 7, 1810-1823
12. Liu, R., Li, Z., Bai, S., Zhang, H., Tang, M., Lei, Y., Chen, L., Liang, S., Zhao, Y. L., Wei, Y., and Huang, C. (2009) Mechanism of cancer cell adaptation to metabolic stress: Proteomics identification of a novel thyroid hormone- mediated gastric carcinogenic signaling pathway. Mol. Cell. Proteomics 8, 70-85
13. Jensen, L. J., Kuhn, M., Stark, M., Chaffron, S., Creevey, C., Muller, J., Doerks, T., Julien, P., Roth, A., Simonovic, M., Bork, P., and von Mering, C. (2009) STRING 8: A global view on proteins and their functional interactions in 630 organisms. Nucleic Acids Res. 37, D412-D416
14. Zhang, S., Cao, Z., Tian, H., Shen, G., Ma, Y., Xie, H., Liu, Y., Zhao, C., Deng, S., Yang, Y., Zheng, R., Li, W., Zhang, N., Liu, S., Wang, W., Dai, L., Shi, S., Cheng, L., Pan, Y., Feng, S., Zhao, X., Deng, H., Yang, S., and Wei, Y. (2011) SKLB1002, a novel potent inhibitor of VEGF receptor 2 signaling, inhibits angiogenesis and tumor growth in vivo. Clin. Cancer Res. 17, 4439-4450
15. Bai, Y., Deng, H., Yang, Y., Zhao, X., Wei, Y., Xie, G., Li, Z., Chen, X., Chen, L., Wang, Y., Su, D., Qian, Z., Zhong, Q., Luo, H., and Yi, T. (2009) VEGF-targeted short hairpin RNA inhibits intraperitoneal ovarian cancer growth in nude mice. Oncology 77, 385-394
16. Ryzhova, E. V., Vos, R. M., Albright, A. V., Harrist, A. V., Harvey, T., and González-Scarano, F. (2006) Annexin 2: A novel human immunodeficiency virus type 1 Gag binding protein involved in replication in monocyte- derived macrophages. J. Virol. 80, 2694-2704 (Pubitemid 43346365)
17. Chen, Y. J., Li, H. Y., Huang, C. H., Twu, N. F., Yen, M. S., Wang, P. H., Chou, T. Y., Liu, Y. N., Chao, K. C., and Yang, M. H. (2010) Oestrogen-induced epithelial-mesenchymal transition of endometrial epithelial cells contributes to the development of adenomyosis. J. Pathol. 222, 261-270
18. Ngô, C., Nicco, C., Leconte, M., Chéreau, C., Arkwright, S., Vacher-Lavenu, M. C., Weill, B., Chapron, C., and Batteux, F. (2010) Protein kinase inhibitors can control the progression of endometriosis in vitro and in vivo. J. Pathol. 222, 148-157
19. Nie, J., Liu, X., and Guo, S. W. (2010) Immunoreactivity of oxytocin receptor and transient receptor potential vanilloid type 1 and its correlation with dysmenorrhea in adenomyosis. Am. J. Obst. Gynecol. 202, 346.e1-346.e8
20. Lu, Y., Nie, J., Liu, X., Zheng, Y., and Guo, S. W. (2010) Trichostatin A, a histone deacetylase inhibitor, reduces lesion growth and hyperalgesia in experimentally induced endometriosis in mice. Hum. Reprod. 25, 1014-1025
21. Dang, Y. H., Xing, B., Zhao, Y., Zhao, X. J., Huo, F. Q., Tang, J. S., Qu, C. L., and Chen, T. (2011) The role of dopamine receptors in ventrolateral orbital cortex-evoked antinociception in a rat formalin test model. Eur. J. Pharmacol. 657, 97-103
22. Won, K. J., Lee, P., Jung, S. H., Jiang, X., Lee, C. K., Lin, H. Y., Kang, H., Lee, H. M., Kim, J., Toyokuni, S., and Kim, B. (2011) 3-Morpholinosydnonimine participates in the attenuation of neointima formation via inhibition of annexin A2-mediated vascular smooth muscle cell migration. Proteomics 11, 193-201
23. Lokman, N. A., Ween, M. P., Oehler, M. K., and Ricciardelli, C. (2011) The role of annexin A2 in tumorigenesis and cancer progression. Cancer Microenviron. 4, 199-208
24. Eyster, K. M., Klinkova, O., Kennedy, V., and Hansen, K. A. (2007) Whole genome deoxyribonucleic acid microarray analysis of gene expression in ectopic versus eutopic endometrium. Fertil. Steril. 88, 1505-1533 (Pubitemid 350216849)
25. Hever, A., Roth, R. B., Hevezi, P., Marin, M. E., Acosta, J. A., Acosta, H., Rojas, J., Herrera, R., Grigoriadis, D., White, E., Conlon, P. J., Maki, R. A., and Zlotnik, A. (2007) Human endometriosis is associated with plasma cells and overexpression of B lymphocyte stimulator. Proc. Natl. Acad. Sci. U.S.A. 104, 12451-12456 (Pubitemid 47206158)
26. Burney, R. O., Talbi, S., Hamilton, A. E., Vo, K. C., Nyegaard, M., Nezhat, C. R., Lessey, B. A., and Giudice, L. C. (2007) Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis. Endocrinology 148, 3814-3826 (Pubitemid 47105847)
27. Tsuji, T., Ibaragi, S., and Hu, G. F. (2009) Epithelial-mesenchymal transition and cell cooperativity in metastasis. Cancer Res. 69, 7135-7139
28. Dhawan, P., Singh, A. B., Deane, N. G., No, Y., Shiou, S. R., Schmidt, C., Neff, J., Washington, M. K., and Beauchamp, R. D. (2005) Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. J. Clin. Invest. 115, 1765-1776 (Pubitemid 40979715)
29. Sood, A.K, Armaiz-Pena, G. N., Halder, J., Nick, A. M., Stone, R. L., Hu, W., Carroll, A. R., Spannuth, W. A., Deavers, M. T., Allen, J. K., Han, L. Y., Kamat, A. A., Shahzad, M. M., McIntyre, B. W., Diaz-Montero, C. M., Jennings, N. B., Lin, Y. G., Merritt, W. M., DeGeest, K., Vivas-Mejia, P. E., Lopez-Berestein, G., Schaller, M. D., Cole, S. W., and Lutgendorf, S. K. (2010) Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis. J. Clin. Invest. 120, 1515-1523
30. Liu, X., and Guo, S. W. (2011) Valproic acid alleviates generalized hyperalgesia in mice with induced adenomyosis. J. Obst. Gynaecol. Res. 37, 696-708
31. Al-Hendy, A., and Salama, S. (2006) Gene therapy and uterine leiomyoma: A review. Hum. Reprod. Update 12, 385-400 (Pubitemid 43923413)
32. Bulun, S. E., Monsavais, D., Pavone, M. E., Dyson, M., Xue, Q., Attar, E., Tokunaga, H., and Su, E. J. (2012) Role of estrogen receptor-β in endometriosis. Semin. Reprod. Med. 30, 39-45
33. Lecart, M. P., and Reginster, J. Y. (2011) Current options for the management of postmenopausal osteoporosis. Expert Opin. Pharmacother. 12, 2533-2552
34. Morissette, M., Al Sweidi, S., Callier, S., and Di Paolo, T. (2008) Estrogen and SERM neuroprotection in animal models of Parkinson's disease. Mol. Cell. Endocrinol. 290, 60-69
35. Lam, E. W., Shah, K., and Brosens, J. J. (2012) The diversity of sex steroid action: The role of micro-RNAs and FOXO transcription factors in cycling endometrium and cancer. J. Endocrinol. 212, 13-25
36. Flamini, M. I., Sanchez, A. M., Genazzani, A. R., and Simoncini, T. (2011) Estrogen regulates endometrial cell cytoskeletal remodeling and motility via focal adhesion kinase. Fertil. Steril. 95, 722-726
37. Mussunoor, S., and Murray, G. I. (2008) The role of annexins in tumour development and progression. J. Pathol. 216, 131-140
38. Sharma, M. C., and Sharma, M. (2007) The role of annexin II in angiogenesis and tumor progression: A potential therapeutic target. Curr. Pharm. Des. 13, 3568-3575 (Pubitemid 350238927)
39. Rescher, U., Ludwig, C., Konietzko, V., Kharitonenkov, A., and Gerke, V. (2008) Tyrosine phosphorylation of annexin A2 regulates Rho-mediated actin rearrangement and cell adhesion. J. Cell Sci. 121, 2177-2185
40. Valapala, M., Thamake, S. I., and Vishwanatha, J. K. (2011) A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events. J. Cell Sci. 124, 1453-1464
41. Weber, G. F., Bjerke, M. A., and DeSimone, D. W. (2011) Integrins and cadherins join forces to form adhesive networks. J. Cell Sci. 124, 1183-1193
42. Semenza, G. L. (2003) Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer 3, 721-732
43. Garcia, J. A. (2006) HIFing the brakes: Therapeutic opportunities for treatment of human malignancies. Sci STKE 2006, pe25
44. Blagosklonny, M. V. (2004) Antiangiogenic therapy and tumor progression. Cancer Cell 5, 13-17