메뉴 건너뛰기




Volumn 25, Issue 4, 2012, Pages 444-449

Pain and genetics

Author keywords

genetics; opioids; pain; pharmacogenomics

Indexed keywords

ADRENALIN; ANALGESIC AGENT; ATP BINDING CASSETTE SUBFAMILY B1; CATECHOL METHYLTRANSFERASE; CODEINE; CYTOCHROME P450 2D6; DELTA OPIATE RECEPTOR; DOPAMINE; FENTANYL; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; KAPPA OPIATE RECEPTOR; MELANOCORTIN 1 RECEPTOR; MEMBRANE PROTEIN; MORPHINE; MU 1 OPIATE RECEPTOR; MU OPIATE RECEPTOR; NORADRENALIN; OXALIPLATIN; OXYCODONE; OXYMORPHONE; PARACETAMOL PLUS TRAMADOL; SUFENTANIL; TRAMADOL; UNCLASSIFIED DRUG;

EID: 84863793670     PISSN: 09527907     EISSN: 14736500     Source Type: Journal    
DOI: 10.1097/ACO.0b013e3283556228     Document Type: Review
Times cited : (25)

References (41)
  • 1
    • 84861371524 scopus 로고    scopus 로고
    • Genomics: Implications for anesthesia, perioperative care and outcomes
    • Body SC. Genomics: Implications for anesthesia, perioperative care and outcomes. Adv Anesth 2009; 27:73-94.
    • (2009) Adv. Anesth. , vol.27 , pp. 73-94
    • Body, S.C.1
  • 3
    • 70350724723 scopus 로고    scopus 로고
    • Anesthesia and pharmacogenomics: not ready for prime time
    • Candiotti KA. Anesthesia and pharmacogenomics: not ready for prime time. Anesth Analg 2009; 109:1377-1378.
    • (2009) Anesth. Analg. , vol.109 , pp. 1377-1378
    • Candiotti, K.A.1
  • 4
    • 34247350020 scopus 로고    scopus 로고
    • Opioid analgesics and antagonists
    • Katzung BG, editor. 10th e.d. New York McGraw-Hill
    • Schumacher MA, Basbaum AI, Way WL. Opioid analgesics and antagonists. In: Katzung BG, editor. Basic and clinical pharmacology. 10th ed. New York: McGraw-Hill; 2006. pp. 492.
    • (2006) Basic and Clinical Pharmacology , pp. 492
    • Schumacher, M.A.1    Basbaum, A.I.2    Way, W.L.3
  • 5
    • 79957843089 scopus 로고    scopus 로고
    • Peripherally acting opioids and clinical implications for pain control
    • Sehgal N, Smith HS, Manchikanti L. Peripherally acting opioids and clinical implications for pain control. Pain Physician 2011; 14:249-258.
    • (2011) Pain Physician , vol.14 , pp. 249-258
    • Sehgal, N.1    Smith, H.S.2    Manchikanti, L.3
  • 6
    • 84858001528 scopus 로고    scopus 로고
    • Human mu-opioid receptor gene A118G polymorphism predicts the efficacy of tramadol/acetaminophen combination tablets (Ultracet) in oxaliplatin-induced painful neuropathy cancer
    • Liu YC, Wang WS. Human mu-opioid receptor gene A118G polymorphism predicts the efficacy of tramadol/acetaminophen combination tablets (Ultracet) in oxaliplatin-induced painful neuropathy cancer. Cancer 2012; 118:1718-1725.
    • (2012) Cancer , Issue.118 , pp. 1718-1725
    • Liu, Y.C.1    Wang, W.S.2
  • 7
    • 33746608902 scopus 로고    scopus 로고
    • Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy
    • Chou WY, Wang CH, Liu PH, et al. Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy. Anesthesiology 2006; 105:334-337.
    • (2006) Anesthesiology , vol.105 , pp. 334-337
    • Chou, W.Y.1    Wang, C.H.2    Liu, P.H.3
  • 10
    • 84856622603 scopus 로고    scopus 로고
    • Lack of association of OPRM1 and ABCB1 single nucleotide polymorphisms to oxycodone response in postoperative pain
    • Zwisler ST, Enggaard TP, Mikkelsen S, et al. Lack of association of OPRM1 and ABCB1 single nucleotide polymorphisms to oxycodone response in postoperative pain. J Clin Pharmacol 2012; 52:234-242.
    • (2012) J. Clin. Pharmacol. , Issue.52 , pp. 234-242
    • Zwisler, S.T.1    Enggaard, T.P.2    Mikkelsen, S.3
  • 11
    • 84855830042 scopus 로고    scopus 로고
    • Effect of l-opioid receptor A118G polymorphism on the ED50 of epidural sufentanil for labor analgesia
    • Camorcia M, Capogna G, Stirparo S, et al. Effect of l-opioid receptor A118G polymorphism on the ED50 of epidural sufentanil for labor analgesia. Int J Obstet Anesth 2012; 21:40-44.
    • (2012) Int. J. Obstet. Anesth. , Issue.21 , pp. 40-44
    • Camorcia, M.1    Capogna, G.2    Stirparo, S.3
  • 12
    • 73449088010 scopus 로고    scopus 로고
    • Association of human m-opioid receptor gene polymorphism A118G with fentanyl analgesia consumption in Chinese gynaecological patients
    • Zhang W, Chang YZ, Kan QC, et al. Association of human m-opioid receptor gene polymorphism A118G with fentanyl analgesia consumption in Chinese gynaecological patients. Anaesthesia 2010; 65:130-135.
    • (2010) Anaesthesia , vol.65 , pp. 130-135
    • Zhang, W.1    Chang, Y.Z.2    Kan, Q.C.3
  • 13
    • 70350620288 scopus 로고    scopus 로고
    • Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment
    • Walter C, Lötsch J. Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment. Pain 2009; 146:270-275.
    • (2009) Pain , vol.146 , pp. 270-275
    • Walter, C.1    Lötsch, J.2
  • 14
    • 78349309752 scopus 로고    scopus 로고
    • Biological pathways and genetic variables involved in pain
    • Shi Q, Cleeland CS, Klepstad P, et al. Biological pathways and genetic variables involved in pain. Qual Life Res 2010; 19:1407-1417.
    • (2010) Qual. Life Res. , vol.19 , pp. 1407-1417
    • Shi, Q.1    Cleeland, C.S.2    Klepstad, P.3
  • 15
    • 40949150784 scopus 로고    scopus 로고
    • Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief
    • Campa D, Gioia A, Tomei A, et al. Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief. Clin Pharmacol Ther 2008; 83:559-566.
    • (2008) Clin. Pharmacol. Ther. , vol.83 , pp. 559-566
    • Campa, D.1    Gioia, A.2    Tomei, A.3
  • 16
    • 70149109673 scopus 로고    scopus 로고
    • Cross-sectional analysis of the influence of currently known pharmacogenetic modulators on opioid therapy in outpatient pain centers
    • Lötsch J, von Hentig N, Freynhagen R, et al. Cross-sectional analysis of the influence of currently known pharmacogenetic modulators on opioid therapy in outpatient pain centers. Pharmacogenet Genomics 2009; 19:429-436.
    • (2009) Pharmacogenet Genomics , vol.19 , pp. 429-436
    • Lötsch, J.1    Von Hentig, N.2    Freynhagen, R.3
  • 17
    • 77954398116 scopus 로고    scopus 로고
    • The antinociceptive effect and adverse drug reactions of oxycodone in human experimental pain in relation to genetic variations in the OPRM1 and ABCB1 genes
    • Zwisler ST, Enggaard TP, Noehr-Jensen L, et al. The antinociceptive effect and adverse drug reactions of oxycodone in human experimental pain in relation to genetic variations in the OPRM1 and ABCB1 genes. Fundam Clin Pharmacol 2010; 24:517-524.
    • (2010) Fundam Clin. Pharmacol. , vol.24 , pp. 517-524
    • Zwisler, S.T.1    Enggaard, T.P.2    Noehr-Jensen, L.3
  • 18
    • 20444451123 scopus 로고    scopus 로고
    • The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients
    • Rakva'g TT, Klepstad P, Baar C, et al. The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients. Pain 2005; 116:73-78.
    • (2005) Pain , vol.116 , pp. 73-78
    • Rakva'g, T.T.1    Klepstad, P.2    Baar, C.3
  • 19
    • 81455127299 scopus 로고    scopus 로고
    • The catechol-o-methyltransferase (COMT) val158met polymorphismaffects brain responses to repeated painful stimuli
    • Loggia ML, Jensen K, Gollub RL, et al. The catechol-o-methyltransferase (COMT) val158met polymorphismaffects brain responses to repeated painful stimuli. PLoS One 2011; 6:e27764.
    • (2011) Plos One , vol.6
    • Loggia, M.L.1    Jensen, K.2    Gollub, R.L.3
  • 20
    • 0037458277 scopus 로고    scopus 로고
    • COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor
    • Zubieta JK, Heitzeg MM, Smith YR, et al. COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor. Science 2003; 299:1240-1243.
    • (2003) Science , vol.299 , pp. 1240-1243
    • Zubieta, J.K.1    Heitzeg, M.M.2    Smith, Y.R.3
  • 21
    • 77952788152 scopus 로고    scopus 로고
    • The val158met polymorphism of human catechol-O-methyltransferase (COMT) affects anterior cingulate cortex activation in response to painful laser stimulation
    • Mobascher A, Brinkmeyer J, Thiele H, et al. The val158met polymorphism of human catechol-O-methyltransferase (COMT) affects anterior cingulate cortex activation in response to painful laser stimulation. Mol Pain 2010; 6:32.
    • (2010) Mol. Pain , vol.6 , pp. 32
    • Mobascher, A.1    Brinkmeyer, J.2    Thiele, H.3
  • 22
    • 67650308690 scopus 로고    scopus 로고
    • Increased sensitivity to thermal pain following a single opiate dose is influenced by the comt val158met polymorphism
    • Jensen KB, Lonsdorf TB, Schalling M, et al. Increased Sensitivity to Thermal Pain Following a Single Opiate Dose Is Influenced by the COMT val158met Polymorphism. PLoS One 2009; 4:e6016.
    • (2009) Plos One , vol.4
    • Jensen, K.B.1    Lonsdorf, T.B.2    Schalling, M.3
  • 23
    • 80052765974 scopus 로고    scopus 로고
    • Persistent pain after mastectomy with reconstruction
    • HickeyOT, Nugent NF, Burke SM, et al. Persistent pain after mastectomy with reconstruction. J Clin Anesth 2011; 23:482-488.
    • (2011) J. Clin. Anesth. , vol.23 , pp. 482-488
    • Hickey, O.T.1    Nugent, N.F.2    Burke, S.M.3
  • 24
    • 84863722198 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase genotype (Val158met) modulates cancerrelated fatigue and pain sensitivity in breast cancer survivors
    • Fernández-De-Las-Peñas C, Fernández-Lao C, Cantarero-Villanueva I, et al. Catechol-O-methyltransferase genotype (Val158met) modulates cancerrelated fatigue and pain sensitivity in breast cancer survivors. Breast Cancer Res Treat 2012; 133:405-412.
    • (2012) Breast Cancer Res. Treat , Issue.133 , pp. 405-412
    • Fernández-De-Las-Peñas, C.1    Fernández-Lao, C.2    Cantarero-Villanueva, I.3
  • 25
    • 84863797021 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase genotype predicts pain severity in hospitalized burn patients
    • Epub ahead of print]
    • Orrey DC, Bortsov AV, Hoskins JM, et al. Catechol-O-methyltransferase genotype predicts pain severity in hospitalized burn patients. J Burn Care Res 2012. [Epub ahead of print]
    • (2012) J. Burn Care Res.
    • Orrey, D.C.1    Bortsov, A.V.2    Hoskins, J.M.3
  • 26
    • 79551541573 scopus 로고    scopus 로고
    • Catecholamine-O-methyltransferase polymorphisms are associated with postoperative pain intensity
    • Lee PJ, Delaney P, Keogh J, et al. Catecholamine-O-methyltransferase polymorphisms are associated with postoperative pain intensity. Clin J Pain 2011; 27:93-101.
    • (2011) Clin. J. Pain , vol.27 , pp. 93-101
    • Lee, P.J.1    Delaney, P.2    Keogh, J.3
  • 27
    • 19944427292 scopus 로고    scopus 로고
    • Genetic basis for individual variations in pain perception and the development of a chronic pain condition
    • Diatchenko L, Slade GD, Nackley AG, et al. Genetic basis for individual variations in pain perception and the development of a chronic pain condition. Hum Mol Genet 2005; 14:135-143.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 135-143
    • Diatchenko, L.1    Slade, G.D.2    Nackley, A.G.3
  • 28
    • 61349086157 scopus 로고    scopus 로고
    • Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain
    • Rakva'g TT, Ross JR, Sato H, et al. Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain. Mol Pain 2008; 4:64.
    • (2008) Mol. Pain , vol.4 , pp. 64
    • Rakva'g, T.T.1    Ross, J.R.2    Sato, H.3
  • 29
    • 79953890859 scopus 로고    scopus 로고
    • CYP2D6 in the metabolism of opioids for mild to moderate pain
    • Leppert W. CYP2D6 in the metabolism of opioids for mild to moderate pain. Pharmacology 2011; 87:274-285.
    • (2011) Pharmacology , vol.87 , pp. 274-285
    • Leppert, W.1
  • 30
    • 14844360833 scopus 로고    scopus 로고
    • Influence of CYP2D6 genetics on opioid kinetics, metabolism and response
    • Mikus G, Weiss J. Influence of CYP2D6 genetics on opioid kinetics, metabolism and response. Curr Pharmacogenomics 2005; 3:43-52.
    • (2005) Curr. Pharmacogenomics , vol.3 , pp. 43-52
    • Mikus, G.1    Weiss, J.2
  • 31
    • 68349144595 scopus 로고    scopus 로고
    • The impact of CYP2D6 genetic polymorphism on postoperative morphine pain relief
    • Candiotti KA, Yang Z, Rodriguez Y, et al. The impact of CYP2D6 genetic polymorphism on postoperative morphine pain relief. Pain Med 2009; 10:799-805.
    • (2009) Pain Med. , vol.10 , pp. 799-805
    • Candiotti, K.A.1    Yang, Z.2    Rodriguez, Y.3
  • 32
    • 77952869071 scopus 로고    scopus 로고
    • Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety
    • Samer CF, Daali Y, Wagner M, et al. Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety. Br J Pharmacol 2010; 160:919-930.
    • (2010) Br. J. Pharmacol. , vol.160 , pp. 919-930
    • Samer, C.F.1    Daali, Y.2    Wagner, M.3
  • 33
    • 84857045805 scopus 로고    scopus 로고
    • Do CYP2D6 genotypes reflect oxycodone requirements for cancer patients treated for cancer pain? A crosssectional multicentre study
    • Andreassen TN, Eftedal I, Klepstad P, et al. Do CYP2D6 genotypes reflect oxycodone requirements for cancer patients treated for cancer pain? A crosssectional multicentre study. Eur J Clin Pharmacol 2012; 68:55-64.
    • (2012) Eur. J. Clin. Pharmacol. , Issue.68 , pp. 55-64
    • Andreassen, T.N.1    Eftedal, I.2    Klepstad, P.3
  • 34
    • 34547644659 scopus 로고    scopus 로고
    • Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication
    • Kirchheiner J, Schmidt H, Tzvetkov M, et al. Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication. Pharmacogenomics J 2007; 7:257-265.
    • (2007) Pharmacogenomics J. , vol.7 , pp. 257-265
    • Kirchheiner, J.1    Schmidt, H.2    Tzvetkov, M.3
  • 35
    • 33746012401 scopus 로고    scopus 로고
    • Postoperative pain, morphine, consumption and genetic polymorphism of IL-1b and IL-1 receptor antagonist
    • Bessler H, Shavit Y, Mayburd E, et al. Postoperative pain, morphine, consumption and genetic polymorphism of IL-1b and IL-1 receptor antagonist. Neurosci Lett 2006; 404 (1-2):154-158.
    • (2006) Neurosci. Lett. , vol.404 , Issue.1-2 , pp. 154-158
    • Bessler, H.1    Shavit, Y.2    Mayburd, E.3
  • 36
    • 79955465580 scopus 로고    scopus 로고
    • Polymorphism in the interleukin-1 receptor antagonist gene is associated with serum interleukin-1 receptor antagonist concentrations and postoperative opioid consumption
    • Candiotti K, Yang Z, Morris R, et al. Polymorphism in the interleukin-1 receptor antagonist gene is associated with serum interleukin-1 receptor antagonist concentrations and postoperative opioid consumption. Anesthesiology 2011; 114:1162-1168.
    • (2011) Anesthesiology , vol.114 , pp. 1162-1168
    • Candiotti, K.1    Yang, Z.2    Morris, R.3
  • 37
    • 79959834855 scopus 로고    scopus 로고
    • Increased interleukin-1 gene expression in peripheral blood leukocytes is associated with increased pain and predicts risk for progression of symptomatic knee osteoarthritis
    • AtturM, Belitskaya-Lévy I, Oh C, et al. Increased interleukin-1 gene expression in peripheral blood leukocytes is associated with increased pain and predicts risk for progression of symptomatic knee osteoarthritis. Arthritis Rheum 2011; 63:1908-1917.
    • (2011) Arthritis. Rheum. , vol.63 , pp. 1908-1917
    • Attur, M.1    Belitskaya-Lévy, I.2    Oh, C.3
  • 38
    • 79960862976 scopus 로고    scopus 로고
    • A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee
    • Cohen SB, Proudman S, Kivitz AJ, et al. A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee. Arthritis Res Ther 2011; 13:R125.
    • (2011) Arthritis. Res. Ther. , vol.13
    • Cohen, S.B.1    Proudman, S.2    Kivitz, A.J.3
  • 39
    • 0344341625 scopus 로고    scopus 로고
    • The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans
    • Mogil JS, Wilson SG, Chesler EJ, et al. The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans. Proc Natl Acad Sci U S A 2003; 100:4867-4872.
    • (2003) Proc. Natl. Acad. Sci. U S A. , vol.100 , pp. 4867-4872
    • Mogil, J.S.1    Wilson, S.G.2    Chesler, E.J.3
  • 40
    • 22244492308 scopus 로고    scopus 로고
    • Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans
    • Mogil JS, Ritchie J, Smith SB, et al. Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans. J Med Genet 2005; 42:583-587.
    • (2005) J. Med. Genet. , vol.42 , pp. 583-587
    • Mogil, J.S.1    Ritchie, J.2    Smith, S.B.3
  • 41
    • 77958585653 scopus 로고    scopus 로고
    • Involvement of the melanocortin-1 receptor in acute pain and pain of inflammatory but not neuropathic origin
    • Delaney A, Keighren M, Fleetwood-Walker SM, Jackson IJ. Involvement of the melanocortin-1 receptor in acute pain and pain of inflammatory but not neuropathic origin. PLoS One 2010; 5:e12498.
    • (2010) Plos. One , vol.5
    • Delaney, A.1    Keighren, M.2    Fleetwood-Walker, S.M.3    Jackson, I.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.