Association of poor insight in schizophrenia with structure and function of cortical midline structures and frontopolar cortex

Schizophrenia Research

Volumn 139, Issue 1-3, 2012, Pages 27-32

  Raij, Tuukka T ^a,b   Riekki, Tapani J J ^c   Hari, Riitta ^a  

^a AALTO UNIVERSITY   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Brain; Cortical midline structures; Frontopolar cortex; Functional magnetic resonance imaging; Insight; Psychosis; Schizophrenia

Indexed keywords

CHLORPROMAZINE;

ADULT; ARTICLE; BRAIN CORTEX; BRAIN DEPTH STIMULATION; BRAIN DISEASE; BRAIN SIZE; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DEPRESSION; DISEASE ASSOCIATION; FEMALE; FRONTOPOLAR CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; INTROSPECTION; MALE; MENTAL TASK; NEGATIVE SYNDROME; NEUROANATOMY; POSITIVE SYNDROME; PRIORITY JOURNAL; SCHIZOPHRENIA; STRUCTURE ANALYSIS; THOUGHT DISORDER; VOXEL BASED MORPHOMETRY;

ADULT; BRAIN MAPPING; CEREBRAL CORTEX; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; STATISTICS AS TOPIC; YOUNG ADULT;

EID: 84863774790     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2012.05.011     Document Type: Article

References (50)

1. Addington D., Addington J., Maticka-Tyndale E. Assessing depression in schizophrenia: the Calgary Depression Scale. Br. J. Psychiatry Suppl. 1993, 22:39-44.
2. Aleman A., Agrawal N., Morgan K.D., David A.S. Insight in psychosis and neuropsychological function: meta-analysis. Br. J. Psychiatry 2006, 189(3):204-212.
3. Amador X.F., Strauss D.H., Yale S.A., Flaum M.M., Endicott J., Gorman J.M. Assessment of insight in psychosis. Am. J. Psychiatry 1993, 150(6):873-879.
4. Andreasen N.C., Pressler M., Nopoulos P., Miller D., Ho B.C. Antipsychotic dose equivalents and dose-years: a standardized method for comparing exposure to different drugs. Biol. Psychiatry 2010, 67(3):255-262.
5. Antonius D., Prudent V., Rebani Y., D'Angelo D., Ardekani B.A., Malaspina D., Hoptman M.J. White matter integrity and lack of insight in schizophrenia and schizoaffective disorder. Schizophr. Res. 2011, 128(1-3):76-82.
6. Arango C., Amador X. Lessons learned about poor insight. Schizophr. Bull. 2011, 37(1):2728.
7. Arango C., Adami H., Sherr J.D., Thaker G.K., Carpenter W.T. Relationship of awareness of dyskinesia in schizophrenia to insight into mental illness. Am. J. Psychiatry 1999, 156(7):1097-1099.
8. Ashburner J. A fast diffeomorphic image registration algorithm. NeuroImage 2007, 38(1):95-113.
9. Ashburner J., Friston K.J. Voxel-based morphometry-the methods. NeuroImage 2000, 11(6):805-821.
10. Birchwood M., Smith J., Drury V., Healy J., Macmillan F., Slade M. A self-report insight scale for psychosis: reliability, validity and sensitivity to change. Acta Psychiatr. Scand. 1994, 89(1):62-67.
11. Buckner R.L., Carroll D.C. Self-projection and the brain. Trends Cogn. Sci. 2007, 11(2):49-57.
12. Chan R.C., Di X., McAlonan G.M., Gong Q.Y. Brain anatomical abnormalities in high-risk individuals, first-episode, and chronic schizophrenia: an activation likelihood estimation meta-analysis of illness progression. Schizophr. Bull. 2011, 37(1):177-188.
13. Cooke M.A., Fannon D., Kuipers E., Peters E., Williams S.C., Kumari V. Neurological basis of poor insight in psychosis: a voxel-based MRI study. Schizophr. Res. 2008, 103(1-3):40-51.
14. Ellison-Wright I., Bullmore E. Meta-analysis of diffusion tensor imaging studies in schizophrenia. Schizophr. Res. 2009, 108(1-3):3-10.
15. Ellison-Wright I., Glahn D.C., Laird A.R., Thelen S.M., Bullmore E. The anatomy of first-episode and chronic schizophrenia: an anatomical likelihood estimation meta-analysis. Am. J. Psychiatry 2008, 165(8):1015-1023.
16. First M., Spitzer R., Gibbon M., Williams J. Structured Clinical Interview for Axis I DSM-IV Disorders-Non-patient Edition 1996, Biometrics Research Department, State Psychiatric Institute, New York.
17. Fleming S.M., Weil R.S., Nagy Z., Dolan R.J., Rees G. Relating introspective accuracy to individual differences in brain structure. Science 2010, 329(5998):1541-1543.
18. Friston K.J., Ashburner J., Frith C.D., Poline J.-P., Heather J.D., Frackowiak R.S.J. Spatial registration and normalization of images. Hum. Brain Mapp. 1995, 2(3):165-189.
19. Garrity A.G., Pearlson G.D., McKiernan K., Lloyd D., Kiehl K.A., Calhoun V.D. Aberrant "default mode" functional connectivity in schizophrenia. Am. J. Psychiatry 2007, 164(3):450-457.
20. Gilleen J., Greenwood K., David A.S. Domains of awareness in schizophrenia. Schizophr. Bull. 2011, 37(1):61-72.
21. Goghari V.M., Sponheim S.R., MacDonald A.W. The functional neuroanatomy of symptom dimensions in schizophrenia: a qualitative and quantitative review of a persistent question. Neurosci. Biobehav. Rev. 2010, 34(3):468-486.
22. Golden C. Stroop Colour and Word Test: A Manual for Clinical and Experimental Uses 1978, Stoelting, Wood Dale, IL.
23. Gusnard D.A., Raichle M.E. Searching for a baseline: functional imaging and the resting human brain. Nat. Rev. Neurosci. 2001, 2(10):685-694.
24. Ha T.H., Youn T., Ha K.S., Rho K.S., Lee J.M., Kim I.Y., Kim S.I., Kwon J.S. Gray matter abnormalities in paranoid schizophrenia and their clinical correlations. Psychiatry Res. 2004, 132(3):251-260.
25. Holt D.J., Cassidy B.S., Andrews-Hanna J.R., Lee S.M., Coombs G., Goff D.C., Gabrieli J.D., Moran J.M. An anterior-to-posterior shift in midline cortical activity in schizophrenia during self-reflection. Biol. Psychiatry 2011, 69(5):415-423.
26. Johnson S.C., Baxter L.C., Wilder L.S., Pipe J.G., Heiserman J.E., Prigatano G.P. Neural correlates of self-reflection. Brain 2002, 125(8):1808-1814.
27. Kawasak Y., Vogeley K., Jung V., Tepest R., Hutte H., Schleicher A., Falkai P. Automated image analysis of disturbed cytoarchitecture in Brodmann area 10 in schizophrenia: a post-mortem study. Prog. Neuropsychopharmacol. Biol. Psychiatry 2000, 24(7):1093-1094.
28. Kay S.R., Fiszbein A., Opler L.A. The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr. Bull. 1987, 13(2):261-276.
29. Kriegeskorte N., Simmons W.K., Bellgowan P.S.F. Circular analysis in systems neuroscience: the dangers of double dipping. Nat. Neurosci. 2009, 12(5):535-540.
30. Lee K.H., Brown W.H., Egleston P.N., Green R.D., Farrow T.F., Hunter M.D., Parks R.W., Wilkinson I.D., Spence S.A., Woodruff P.W. A functional magnetic resonance imaging study of social cognition in schizophrenia during an acute episode and after recovery. Am. J. Psychiatry 2006, 163(11):1926-1933.
31. Lincoln T.M., Lullmann E., Rief W. Correlates and long-term consequences of poor insight in patients with schizophrenia. A systematic review. Schizophr. Bull. 2007, 33(6):1324-1342.
32. Mason M.F., Norton M.I., Van Horn J.D., Wegner D.M., Grafton S.T., Macrae C.N. Wandering minds: the default network and stimulus-independent thought. Science 2007, 315(5810):393-395.
33. McEvoy J.P., Apperson L.J., Appelbaum P.S., Ortlip P., Brecosky J., Hammill K., Geller J.L., Roth L. Insight in schizophrenia. Its relationship to acute psychopathology. J. Nerv. Ment. Dis. 1989, 177(1):43-47.
34. Mechelli A., Price C.J., Friston K.J., Ashburner J. Voxel-based morphometry of the human brain: methods and applications. Curr. Med. Imaging Rev. 2005, 1(1):1-9.
35. Morgan K.D., Dazzan P., Morgan C., Lappin J., Hutchinson G., Suckling J., Fearon P., Jones P.B., Leff J., Murray R.M., David A.S. Insight, grey matter and cognitive function in first-onset psychosis. Br. J. Psychiatry 2010, 197(2):141-148.
36. Murphy E.R., Brent B.K., Benton M., Pruitt P., Diwadkar V., Rajarethinam R.P., Keshavan M.S. Differential processing of metacognitive evaluation and the neural circuitry of the self and others in schizophrenia: a pilot study. Schizophr. Res. 2010, 116(2-3):252-258.
37. Nelson B., Fornito A., Harrison B.J., Yucel M., Sass L.A., Yung A.R., Thompson A., Wood S.J., Pantelis C., McGorry P.D. A disturbed sense of self in the psychosis prodrome: linking phenomenology and neurobiology. Neurosci. Biobehav. Rev. 2009, 33(6):807-817.
38. Northoff G., Bermpohl F. Cortical midline structures and the self. Trends Cogn. Sci. 2004, 8(3):102-107.
39. Olney J.W., Farber N.B. Glutamate receptor dysfunction and schizophrenia. Arch. Gen. Psychiatry 1995, 52(12):998-1007.
40. Osatuke K., Ciesla J., Kasckow J.W., Zisook S., Mohamed S. Insight in schizophrenia: a review of etiological models and supporting research. Compr. Psychiatry 2008, 49(1):70-77.
41. Pomarol-Clotet E., Canales-Rodriguez E.J., Salvador R., Sarro S., Gomar J.J., Vila F., Ortiz-Gil J., Iturria-Medina Y., Capdevila A., McKenna P.J. Medial prefrontal cortex pathology in schizophrenia as revealed by convergent findings from multimodal imaging. Mol. Psychiatry 2010, 15(8):823-830.
42. Rabinowitz T., Peirson R. "Nothing is wrong, doctor": understanding and managing denial in patients with cancer. Cancer Invest. 2006, 24(1):68-76.
43. Raij T.T., Valkonen-Korhonen M., Holi M., Therman S., Lehtonen J., Hari R. Reality of auditory verbal hallucinations. Brain 2009, 132(11):2994-3001.
44. Ramnani N., Owen A.M. Anterior prefrontal cortex: insights into function from anatomy and neuroimaging. Nat. Rev. Neurosci. 2004, 5(5):184-194.
45. Reitan R.M., Wolfson D. The Halstead-Reitan Neuropsychological Test Battery: Theory and Clinical Interpretation 1985, Neuropsychology Press, Tucson, AZ.
46. Schmitz T.W., Rowley H.A., Kawahara T.N., Johnson S.C. Neural correlates of self-evaluative accuracy after traumatic brain injury. Neuropsychologia 2006, 44(5):762-773.
47. Schultz C.C., Koch K., Wagner G., Roebel M., Schachtzabel C., Gaser C., Nenadic I., Reichenbach J.R., Sauer H., Schlosser R.G. Reduced cortical thickness in first episode schizophrenia. Schizophr. Res. 2010, 116(2-3):204-209.
48. van der Meer L., Costafreda S., Aleman A., David A.S. Self-reflection and the brain: a theoretical review and meta-analysis of neuroimaging studies with implications for schizophrenia. Neurosci. Biobehav. Rev. 2010, 34(6):935-946.
49. Wechsler D. Wechsler Adult Intelligence Scale 1997, The Psychological Corporation, San Antonio, TX. third ed.
50. Wechsler D. Wechsler Memory Scale 1997, The Psychological Corporation, San Antonio, TX. third ed.