-
1
-
-
77951156788
-
Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding
-
Andersen J.T., Daba M.B., Berntzen G., Michaelsen T.E., Sandlie I. Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding. Journal of Biological Chemistry 2010, 285:4826-4836.
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 4826-4836
-
-
Andersen, J.T.1
Daba, M.B.2
Berntzen, G.3
Michaelsen, T.E.4
Sandlie, I.5
-
2
-
-
84856726736
-
Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor
-
Article number: 610
-
Andersen J.T., Dalhus B., Cameron J., Daba M.B., Plumridge A., Evans L., et al. Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor. Nature Communications 2012, 3. Article number: 610. 10.1038/ncomms1607.
-
(2012)
Nature Communications
, vol.3
-
-
Andersen, J.T.1
Dalhus, B.2
Cameron, J.3
Daba, M.B.4
Plumridge, A.5
Evans, L.6
-
3
-
-
41949086504
-
Improving oral bioavailability of peptides by multiple N-methylation: somatostatin analogues
-
Biron E., Chatterjee J., Ovadia O., Langenegger D., Brueggen J., Hoyer D., et al. Improving oral bioavailability of peptides by multiple N-methylation: somatostatin analogues. Angewandte Chemie International Edition 2008, 47:2595-2599.
-
(2008)
Angewandte Chemie International Edition
, vol.47
, pp. 2595-2599
-
-
Biron, E.1
Chatterjee, J.2
Ovadia, O.3
Langenegger, D.4
Brueggen, J.5
Hoyer, D.6
-
5
-
-
0019603894
-
Determinants of the glomerular filtration of proteins
-
Deen W.M., Satvat B. Determinants of the glomerular filtration of proteins. American Journal of Physiology 1981, 241:F162-F170.
-
(1981)
American Journal of Physiology
, vol.241
-
-
Deen, W.M.1
Satvat, B.2
-
6
-
-
77956304908
-
Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells
-
Eastwood D., Findlay L., Poole S., Bird C., Wadhwa M., et al. Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells. British Journal of Pharmacology 2010, 161:512-526.
-
(2010)
British Journal of Pharmacology
, vol.161
, pp. 512-526
-
-
Eastwood, D.1
Findlay, L.2
Poole, S.3
Bird, C.4
Wadhwa, M.5
-
7
-
-
34748877223
-
Physiologically-based pharmacokinetic (PBPK) model to predict IgG tissue kinetics in wild-type and FcRn-knockout mice
-
Garg A., Balthasar J.P. Physiologically-based pharmacokinetic (PBPK) model to predict IgG tissue kinetics in wild-type and FcRn-knockout mice. Journal of Pharmacokinetics and Pharmacodynamics 2007, 34:687-709.
-
(2007)
Journal of Pharmacokinetics and Pharmacodynamics
, vol.34
, pp. 687-709
-
-
Garg, A.1
Balthasar, J.P.2
-
8
-
-
79952278379
-
99m Tc-labeling and biodistribution studies of a PNA oligomer containing a new ligand derivative of 2,2'-dipicolylamine
-
99m Tc-labeling and biodistribution studies of a PNA oligomer containing a new ligand derivative of 2,2'-dipicolylamine. Journal of Inorganic Biochemistry 2010, 104:1133-1140.
-
(2010)
Journal of Inorganic Biochemistry
, vol.104
, pp. 1133-1140
-
-
Gasser, G.1
Jaeger, K.2
Zenker, M.3
Bergmann, R.4
Steinbach, J.5
Stephan, H.6
-
9
-
-
0031821074
-
In vivo distribution and metabolism of a phosphorothioate oligonucleotide within rat liver after intravenous administration
-
Graham M.J., Crooke S.T., Monteith D.K., Cooper S.R., Lemonidis K.M., Stecker K.K., et al. In vivo distribution and metabolism of a phosphorothioate oligonucleotide within rat liver after intravenous administration. Journal of Pharmacology and Experimental Therapeutics 1998, 286:447-458.
-
(1998)
Journal of Pharmacology and Experimental Therapeutics
, vol.286
, pp. 447-458
-
-
Graham, M.J.1
Crooke, S.T.2
Monteith, D.K.3
Cooper, S.R.4
Lemonidis, K.M.5
Stecker, K.K.6
-
10
-
-
65549136272
-
Development of a PBPK model for monoclonal antibodies and simulation of human and mice PBPK of a radiolabelled monoclonal antibody
-
Heiskanen T., Heiskanen T., Kairemo K. Development of a PBPK model for monoclonal antibodies and simulation of human and mice PBPK of a radiolabelled monoclonal antibody. Current Pharmaceutical Design 2009, 15:988-1007.
-
(2009)
Current Pharmaceutical Design
, vol.15
, pp. 988-1007
-
-
Heiskanen, T.1
Heiskanen, T.2
Kairemo, K.3
-
11
-
-
77950348118
-
Radioimmunotherapy with anti-CD66 antibody: improving the biodistribution using a physiologically based pharmacokinetic model
-
Kletting P., Kull T., Bunjes D., Mahren B., Luster M., Reske S.N., et al. Radioimmunotherapy with anti-CD66 antibody: improving the biodistribution using a physiologically based pharmacokinetic model. Journal of Nuclear Medicine 2010, 51:484-491.
-
(2010)
Journal of Nuclear Medicine
, vol.51
, pp. 484-491
-
-
Kletting, P.1
Kull, T.2
Bunjes, D.3
Mahren, B.4
Luster, M.5
Reske, S.N.6
-
12
-
-
44449140590
-
Biodistribution of 68Ga-labelled LNA-DNA mixmer antisense oligonucleotides for rat chromagranin-A
-
Lendvai G., Velikyan I., Estrada S., Erikssin B., Langstrom B., Bergstrom M. Biodistribution of 68Ga-labelled LNA-DNA mixmer antisense oligonucleotides for rat chromagranin-A. Oligonucleotides 2008, 18:33-49.
-
(2008)
Oligonucleotides
, vol.18
, pp. 33-49
-
-
Lendvai, G.1
Velikyan, I.2
Estrada, S.3
Erikssin, B.4
Langstrom, B.5
Bergstrom, M.6
-
13
-
-
0141997761
-
Emerging trends in oral delivery of peptide and protein drugs
-
Mahato R.I., Narang A.S., Thoma L., Miller D.D. Emerging trends in oral delivery of peptide and protein drugs. Critical Reviews in Therapeutic Drug Carrier Systems 2003, 20:153-214.
-
(2003)
Critical Reviews in Therapeutic Drug Carrier Systems
, vol.20
, pp. 153-214
-
-
Mahato, R.I.1
Narang, A.S.2
Thoma, L.3
Miller, D.D.4
-
14
-
-
77954865709
-
Combined use of immunoassay and two-dimensional liquid chromatography mass spectrometry for the detection and identification of metabolites from biotherapeutic pharmacokinetic samples
-
Murphy R.E., Kinhikar A.G., Shields M.J., Del Rosario J., Preston R., Levin N., et al. Combined use of immunoassay and two-dimensional liquid chromatography mass spectrometry for the detection and identification of metabolites from biotherapeutic pharmacokinetic samples. Journal of Pharmaceutical and Biomedical Analysis 2010, 53:221-227.
-
(2010)
Journal of Pharmaceutical and Biomedical Analysis
, vol.53
, pp. 221-227
-
-
Murphy, R.E.1
Kinhikar, A.G.2
Shields, M.J.3
Del Rosario, J.4
Preston, R.5
Levin, N.6
-
15
-
-
0035094632
-
Tissue distribution and physiologically based pharmacokinetics of antisense phosphorothioate oligonucleotide ISIS 1082 in rat
-
Peng B., Andrews J., Nestorov I., Brennan B., Nicklin P., Rowland M. Tissue distribution and physiologically based pharmacokinetics of antisense phosphorothioate oligonucleotide ISIS 1082 in rat. Antisense & Nucleic Acid Drug Development 2001, 11:15-27.
-
(2001)
Antisense & Nucleic Acid Drug Development
, vol.11
, pp. 15-27
-
-
Peng, B.1
Andrews, J.2
Nestorov, I.3
Brennan, B.4
Nicklin, P.5
Rowland, M.6
-
16
-
-
0035940080
-
Lymphatic transport of proteins after s.c. injection: implications of animal model selection
-
Porter C.J., Edwards G.A., Charman S.A. Lymphatic transport of proteins after s.c. injection: implications of animal model selection. Advanced Drug Delivery Reviews 2001, 50:157-171.
-
(2001)
Advanced Drug Delivery Reviews
, vol.50
, pp. 157-171
-
-
Porter, C.J.1
Edwards, G.A.2
Charman, S.A.3
-
17
-
-
0033044866
-
Animal pharmacokinetics of the tumor necrosis factor receptor-immunoglobulin fusion protein lenercept and their extrapolation to humans
-
Richter W.F., Gallati H., Schiller C.-D. Animal pharmacokinetics of the tumor necrosis factor receptor-immunoglobulin fusion protein lenercept and their extrapolation to humans. Drug Metabolism and Disposition 1999, 27:21-25.
-
(1999)
Drug Metabolism and Disposition
, vol.27
, pp. 21-25
-
-
Richter, W.F.1
Gallati, H.2
Schiller, C.-D.3
-
19
-
-
84863740786
-
Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human
-
doi:(Epub ahead of print)
-
Shah D.K., Betts A.M., Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human. Journal of Pharmacokinetics and Pharmacodynamics 2011, doi:(Epub ahead of print). 10.1007/2 10928-011-9232-2.
-
(2011)
Journal of Pharmacokinetics and Pharmacodynamics
-
-
Shah, D.K.1
Betts, A.M.2
-
20
-
-
0016222589
-
Role of the kidney in the metabolism of plasma proteins
-
Strober W., Waldmann T.A. Role of the kidney in the metabolism of plasma proteins. Nephron 1974, 13:37-68.
-
(1974)
Nephron
, vol.13
, pp. 37-68
-
-
Strober, W.1
Waldmann, T.A.2
-
21
-
-
0025287316
-
Effect of molecular weight on the lymphatic absorption of water-soluble compounds following subcutaneous administration
-
Supersaxo A., Hein W.R., Steffen H. Effect of molecular weight on the lymphatic absorption of water-soluble compounds following subcutaneous administration. Pharmaceutical Research 1990, 7:167-169.
-
(1990)
Pharmaceutical Research
, vol.7
, pp. 167-169
-
-
Supersaxo, A.1
Hein, W.R.2
Steffen, H.3
-
22
-
-
1842607629
-
Population pharmacokinetic modeling of a subcutaneous depot of GnRH antagonist degarelix
-
Tornoe C.W., Agerso H., Nielsen H.A., Madsen H., Jonsson E.N. Population pharmacokinetic modeling of a subcutaneous depot of GnRH antagonist degarelix. Pharmaceutical Research 2004, 21:574-584.
-
(2004)
Pharmaceutical Research
, vol.21
, pp. 574-584
-
-
Tornoe, C.W.1
Agerso, H.2
Nielsen, H.A.3
Madsen, H.4
Jonsson, E.N.5
-
23
-
-
70349780005
-
Lipoatrophy in GH deficient patients treated with a long-acting pegylated GH
-
Touraine P., D'Souza G.A., Kourides I., Abs R., Barclay P., Xie R., et al. Lipoatrophy in GH deficient patients treated with a long-acting pegylated GH. European Journal of Endocrinology 2009, 161:533-540.
-
(2009)
European Journal of Endocrinology
, vol.161
, pp. 533-540
-
-
Touraine, P.1
D'Souza, G.A.2
Kourides, I.3
Abs, R.4
Barclay, P.5
Xie, R.6
-
25
-
-
53849146426
-
PEGylation of somatropin (recombinant human growth hormone): impact on its clearance in humans
-
Webster R., Xie R., Didier E., Finn R., Finnessy J., Edgington A., et al. PEGylation of somatropin (recombinant human growth hormone): impact on its clearance in humans. Xenobiotica 2008, 38:1340-1351.
-
(2008)
Xenobiotica
, vol.38
, pp. 1340-1351
-
-
Webster, R.1
Xie, R.2
Didier, E.3
Finn, R.4
Finnessy, J.5
Edgington, A.6
-
26
-
-
78649238777
-
PEG and PEG conjugates toxicity: towards an understanding of the the toxicity of PEG and its relevance to PEGylated biologicals
-
Birkhäuser Verlag, F.M. Veronese (Ed.)
-
Webster R., Elliott V., Park B.K., Walker D., Hankin M., Taupin P. PEG and PEG conjugates toxicity: towards an understanding of the the toxicity of PEG and its relevance to PEGylated biologicals. PEGylated Protein Drugs: Basic Science and Clinical Application 2009, 127-146. Birkhäuser Verlag. F.M. Veronese (Ed.).
-
(2009)
PEGylated Protein Drugs: Basic Science and Clinical Application
, pp. 127-146
-
-
Webster, R.1
Elliott, V.2
Park, B.K.3
Walker, D.4
Hankin, M.5
Taupin, P.6
-
27
-
-
33847338002
-
Cross-species pharmacokinetic comparison from mouse to man of a second-generation antisense oligonucleotide, ISIS 301012, targeting human apolipoprotein B-100
-
Yu R.Z., Kim T.W., Hong A., Watanabe T.A., Gaus H.J., Geary R.S. Cross-species pharmacokinetic comparison from mouse to man of a second-generation antisense oligonucleotide, ISIS 301012, targeting human apolipoprotein B-100. Drug Metabolism and Disposition 2007, 35:460-468.
-
(2007)
Drug Metabolism and Disposition
, vol.35
, pp. 460-468
-
-
Yu, R.Z.1
Kim, T.W.2
Hong, A.3
Watanabe, T.A.4
Gaus, H.J.5
Geary, R.S.6
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