Delivery of platelet-derived growth factor as a chemotactic factor for mesenchymal stem cells by bone-mimetic electrospun scaffolds

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Phipps, Matthew C ^a   Xu, Yuanyuan ^a   Bellis, Susan L ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b and Radiation Oncology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; CHEMOTACTIC FACTOR; CXCL16 CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR AB; PLATELET DERIVED GROWTH FACTOR BB; RANTES; STROMAL CELL DERIVED FACTOR 1ALPHA;

ADSORPTION; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CHEMOTAXIS; CONTROLLED STUDY; FLUOROMETRY; HUMAN; HUMAN CELL; MATRIX ATTACHMENT REGION; MESENCHYMAL STEM CELL; MITOGENICITY; PROTEIN BINDING; PROTEIN PURIFICATION; PROTEIN SECRETION; PROTEIN TRANSPORT;

ADSORPTION; ANIMALS; BIOMIMETIC MATERIALS; BONE AND BONES; CATTLE; CELL MIGRATION ASSAYS; CELL PROLIFERATION; CHEMOTACTIC FACTORS; CHEMOTAXIS; COLLAGEN TYPE I; DURAPATITE; FLUORESCENCE; GREEN FLUORESCENT PROTEINS; HUMANS; MESENCHYMAL STROMAL CELLS; MITOGENS; NANOPARTICLES; POLYESTERS; PROTO-ONCOGENE PROTEINS C-SIS; REFERENCE STANDARDS; TIME FACTORS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84863754900     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040831     Document Type: Article

References (43)

1. Lieberman JR, Daluiski A, Einhorn TA, (2002) The role of growth factors in the repair of bone. Biology and clinical applications. J Bone Joint Surg Am 84-A: 1032-1044.
2. Phinney DG, Prockop DJ, (2007) Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair-current views. Stem Cells 25: 2896-2902.
3. Karp JM, Leng Teo GS, (2009) Mesenchymal stem cell homing: the devil is in the details. Cell Stem Cell 4: 206-216.
4. Trippel SB, (1997) Growth factors as therapeutic agents. Instr Course Lect 46: 473-476.
5. Hart CE, Bailey M, Curtis DA, Osborn S, Raines E, et al. (1990) Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets. Biochemistry 29: 166-172.
6. Andrae J, Gallini R, Betsholtz C, (2008) Role of platelet-derived growth factors in physiology and medicine. Genes Dev 22: 1276-1312.
7. Fujii H, Kitazawa R, Maeda S, Mizuno K, Kitazawa S, (1999) Expression of platelet-derived growth factor proteins and their receptor alpha and beta mRNAs during fracture healing in the normal mouse. Histochem Cell Biol 112: 131-138.
8. Ozaki Y, Nishimura M, Sekiya K, Suehiro F, Kanawa M, et al. (2007) Comprehensive analysis of chemotactic factors for bone marrow mesenchymal stem cells. Stem Cells Dev 16: 119-129.
9. Heldin CH, Westermark B, (1999) Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 79: 1283-1316.
10. Kelly JD, Raines EW, Ross R, Murray MJ, (1985) The B chain of PDGF alone is sufficient for mitogenesis. EMBO J 4: 3399-3405.
11. Gruber R, Karreth F, Frommlet F, Fischer MB, Watzek G, (2003) Platelets are mitogenic for periosteum-derived cells. J Orthop Res 21: 941-948.
12. Homsi J, Daud AI, (2007) Spectrum of activity and mechanism of action of VEGF/PDGF inhibitors. Cancer Control 14: 285-294.
13. Hollinger JO, Hart CE, Hirsch SN, Lynch S, Friedlaender GE, (2008) Recombinant human platelet-derived growth factor: biology and clinical applications. J Bone Joint Surg Am 90: 48-54.
14. Solchaga LA, Hee CK, Roach S, Snel LB, (2012) Safety of recombinant human platelet-derived growth factor-BB in Augment((R)) Bone Graft. J Tissue Eng 3: 2041731412442668.
15. Young CS, Bradica G, Hart CE, Karunanidhi A, Street RM, et al. (2011) Preclinical toxicology studies of recombinant human Platelet-Derived Growth Factor-BB either alone or in combination with beta-tricalcium phosphate and type I collagen. J Tissue Eng 2010: 246215.
16. Graham S, Leonidou A, Lester M, Heliotis M, Mantalaris A, et al. (2009) Investigating the role of PDGF as a potential drug therapy in bone formation and fracture healing. Expert Opin Investig Drugs 18: 1633-1654.
17. Solchaga LA, Hee CK, Aguiar DJ, Ratliff J, Turner AS, et al. (2012) Augment bone graft products compare favorably with autologous bone graft in an ovine model of lumbar interbody spine fusion. Spine (Phila Pa 1976) 37: E461-467.
18. Javed F, Al-Askar M, Al-Rasheed A, Al-Hezaimi K, (2011) Significance of the platelet-derived growth factor in periodontal tissue regeneration. Arch Oral Biol 56: 1476-1484.
19. Distler JH, Hirth A, Kurowska-Stolarska M, Gay RE, Gay S, et al. (2003) Angiogenic and angiostatic factors in the molecular control of angiogenesis. Q J Nucl Med 47: 149-161.
20. Bowen-Pope DF, Malpass TW, Foster DM, Ross R, (1984) Platelet-derived growth factor in vivo: levels, activity, and rate of clearance. Blood 64: 458-469.
21. Park YJ, Ku Y, Chung CP, Lee SJ, (1998) Controlled release of platelet-derived growth factor from porous poly(L-lactide) membranes for guided tissue regeneration. J Control Release 51: 201-211.
22. Chen RR, Silva EA, Yuen WW, Mooney DJ, (2007) Spatio-temporal VEGF and PDGF delivery patterns blood vessel formation and maturation. Pharm Res 24: 258-264.
23. Jin Q, Wei G, Lin Z, Sugai JV, Lynch SE, et al. (2008) Nanofibrous scaffolds incorporating PDGF-BB microspheres induce chemokine expression and tissue neogenesis in vivo. PLoS One 3: e1729.
24. Wei G, Jin Q, Giannobile WV, Ma PX, (2006) Nano-fibrous scaffold for controlled delivery of recombinant human PDGF-BB. J Control Release 112: 103-110.
25. Richardson TP, Peters MC, Ennett AB, Mooney DJ, (2001) Polymeric system for dual growth factor delivery. Nat Biotechnol 19: 1029-1034.
26. Liao IC, Wan AC, Yim EK, Leong KW, (2005) Controlled release from fibers of polyelectrolyte complexes. J Control Release 104: 347-358.
27. Lin H, Chen B, Sun W, Zhao W, Zhao Y, et al. (2006) The effect of collagen-targeting platelet-derived growth factor on cellularization and vascularization of collagen scaffolds. Biomaterials 27: 5708-5714.
28. Chen L, He Z, Chen B, Zhao Y, Sun W, et al. (2009) Direct chemical cross-linking of platelet-derived growth factor-BB to the demineralized bone matrix improves cellularization and vascularization. Biomacromolecules 10: 3193-3198.
29. Pham QP, Sharma U, Mikos AG, (2006) Electrospinning of polymeric nanofibers for tissue engineering applications: a review. Tissue Eng 12: 1197-1211.
30. Di Martino A, Liverani L, Rainer A, Salvatore G, Trombetta M, et al. (2011) Electrospun scaffolds for bone tissue engineering. Musculoskelet Surg 95: 69-80.
31. Jang JH, Castano O, Kim HW, (2009) Electrospun materials as potential platforms for bone tissue engineering. Adv Drug Deliv Rev 61: 1065-1083.
32. Prabhakaran MP, Ghasemi-Mobarakeh L, Ramakrishna S, (2011) Electrospun composite nanofibers for tissue regeneration. J Nanosci Nanotechnol 11: 3039-3057.
33. Holzwarth JM, Ma PX, (2011) Biomimetic nanofibrous scaffolds for bone tissue engineering. Biomaterials 32: 9622-9629.
34. Phipps MC, Clem WC, Catledge SA, Xu Y, Hennessy KM, et al. (2011) Mesenchymal stem cell responses to bone-mimetic electrospun matrices composed of polycaprolactone, collagen I and nanoparticulate hydroxyapatite. PLoS One 6: e16813.
35. Phipps MC, Clem WC, Grunda JM, Clines GA, Bellis SL, (2012) Increasing the pore sizes of bone-mimetic electrospun scaffolds comprised of polycaprolactone, collagen I and hydroxyapatite to enhance cell infiltration. Biomaterials 33: 524-534.
36. Ponte AL, Marais E, Gallay N, Langonne A, Delorme B, et al. (2007) The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells 25: 1737-1745.
37. Chamberlain G, Wright K, Rot A, Ashton B, Middleton J, (2008) Murine mesenchymal stem cells exhibit a restricted repertoire of functional chemokine receptors: comparison with human. PLoS One 3: e2934.
38. Lind M, Eriksen EF, Bunger C, (1996) Bone morphogenetic protein-2 but not bone morphogenetic protein-4 and-6 stimulates chemotactic migration of human osteoblasts, human marrow osteoblasts, and U2-OS cells. Bone 18: 53-57.
39. Wilson CJ, Clegg RE, Leavesley DI, Pearcy MJ, (2005) Mediation of biomaterial-cell interactions by adsorbed proteins: a review. Tissue Eng 11: 1-18.
40. Krattinger N, Applegate LA, Biver E, Pioletti DP, Caverzasio J, (2011) Regulation of proliferation and differentiation of human fetal bone cells. Eur Cell Mater 21: 46-58.
41. Canalis E, Varghese S, McCarthy TL, Centrella M (1992) Role of platelet derived growth factor in bone cell function. Growth Regul 2: 151-155.
42. Betsholtz C, Johnsson A, Heldin CH, Westermark B, (1986) Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin. Proc Natl Acad Sci U S A 83: 6440-6444.
43. Yang L, Lin C, Liu ZR, (2006) P68 RNA helicase mediates PDGF-induced epithelial mesenchymal transition by displacing Axin from beta-catenin. Cell 127: 139-155.