Overtreatment and undertreatment of hyperlipidemia in the outpatient setting

Southern Medical Journal

Volumn 105, Issue 7, 2012, Pages 329-333

  Verma, Ashish ^a,b   Visintainer, Paul ^a,b   Elarabi, Mohamed ^a,b   Wartak, Siddharth ^a,b   Rothberg, Michael B ^a,b  

^a BAYSTATE MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

hyperlipidemia; primary care; statins; treatment

Indexed keywords

ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPID; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; AGE; AGED; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; HUMAN; HYPERLIPIDEMIA; HYPERTRIGLYCERIDEMIA; ISCHEMIC HEART DISEASE; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; OUTPATIENT; PATIENT CARE; PRACTICE GUIDELINE; RACE DIFFERENCE; RETROSPECTIVE STUDY; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE;

ADULT; AGED; AGED, 80 AND OVER; AMBULATORY CARE; COMORBIDITY; CORONARY DISEASE; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERLIPIDEMIAS; MALE; MIDDLE AGED; PHYSICIAN'S PRACTICE PATTERNS; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84863752527     PISSN: 00384348     EISSN: 15418243     Source Type: Journal    
DOI: 10.1097/SMJ.0b013e318259bad3     Document Type: Article

References (14)

1. Kuklina EV, Yoon PW, Keenan NL. Trends in high levels of low-density lipoprotein cholesterol in the United States, 1999-2006. JAMA 2009; 302:2104-2110.
2. Yusuf S, Hawken S, Ounpuu S, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study. Lancet 2004;364:937-952.
3. Lewington S, Whitlock G, Clarke R, et al. Blood cholesterol and vascular mortality by age, sex, and blood pressure: A meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet 2007;370:1829-1839.
4. Baigent C, Blackwell L, Emberson J, et al. Efficacy and safety of more intensive lowering of LDL cholesterol: A meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet 2010;376: 1670-1681.
5. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002;106:3143-3421.
6. Foody JM, Krumholz HM. Are statins indicated for the primary prevention of CAD in octogenarians? Antagonist viewpoint. Am J Geriatr Cardiol 2003;12:357-360.
7. National Heart Lung and Blood Institute. Framingham Heart Study: Hard coronary heart disease: 10-year risk. http://www.framinghamheartstudy.org/ risk/hrdcoronary.html. Accessed March 1, 2011.
8. Hayward RA, Krumholz HM, Zulman DM, et al. Optimizing statin treatment for primary prevention of coronary artery disease. Ann Intern Med 2010;152:69-77.
9. Choudhry NK. Copayment levels and medication adherence: less is more. Circulation 2009;119:365-367.
10. Buse JB, Ginsberg HN, Bakris GL, et al. Primary prevention of cardiovascular diseases in people With diabetes mellitus: A scientific statement from the American Heart Association and the American Diabetes Association. Circulation 2007;115:114-126.
11. Abookire SA, Karson AS, Fiskio J, et al. Use and monitoring of "statin" lipid-lowering drugs compared with guidelines. Arch Intern Med 2001; 161:53-58.
12. Gordon WJ, Polansky JM, Boscardin WJ, et al. Coronary risk assessment by point-based vs. equation-based Framingham models: Significant implications for clinical care. J Gen Intern Med 2010;25:1145-1151.
13. Garg AX, Adhikari NK, McDonald H, et al. Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: A systematic review. JAMA 2005;293:1223-1238.
14. Persell SD, Zei C, Cameron KA, et al. Potential use of 10-year and lifetime coronary risk information for preventive cardiology prescribing decisions: A primary care physician survey. Arch Intern Med 2010;170:470-477.