Discriminating thyroid cancers from benign lesions based on differential expression of a limited set of miRNA using paraffin embedded tissues

Indian Journal of Pathology and Microbiology

Volumn 55, Issue 2, 2012, Pages 158-162

  Pai, Rekha ^a   Nehru, G ^a   Samuel, Prasanna ^a   Selvan, Ben ^a   Kumar, Ramani ^a   Jacob, Paul ^a   Nair, Aravindan ^a  

^a CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

Diagnostic markers; miR 221; miR 222; miRNA; thyroid tumors

Indexed keywords

MICRORNA; MICRORNA 187; MICRORNA 221; MICRORNA 222; MICRORNA 224; PARAFFIN; TUMOR MARKER; UNCLASSIFIED DRUG;

ARTICLE; BENIGN TUMOR; CANCER DIAGNOSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; FOLLICULAR VARIANT OF PAPILLARY THYROID CARCINOMA; GENE EXPRESSION; HUMAN; HUMAN TISSUE; POORLY DIFFERENTIATED THYROID CANCER; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; THYROID ADENOMA; THYROID CARCINOMA; THYROID FOLLICULAR CARCINOMA; THYROID PAPILLARY CARCINOMA;

GENE EXPRESSION PROFILING; HUMANS; MICRORNAS; PATHOLOGY, MOLECULAR; THYROID NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 84863738030     PISSN: 03774929     EISSN: 09745130     Source Type: Journal    
DOI: 10.4103/0377-4929.97845     Document Type: Article

References (23)

1. Eszlinger M, Krohn K, Hauptmann S, Dralle H, Giordano TJ, Paschke R. Perspectives for improved and more accurate classification of thyroid epithelial tumors. J Clin Endocrinol Metab 2008;93:3286-94.
2. Hundahl SA, Cady B, Cunningham MP, Mazzaferri E, McKee RF, Rosai J, et al. Initial results from a prospective cohort study of 5583 cases of thyroid carcinoma treated in the United States during 1996. U.S. and German Thyroid Cancer Study Group. An American College of Surgeons Commission on Cancer Patient Care Evaluation study. Cancer 2000;8:202-17.
3. DeLellis RA, Lloyd RV, Heitz PU, Eng C. World Health Organization classification of tumours: pathology and genetics of tumours of endocrine organs. Lyon, France: IARC Press; 2004.
4. Nikiforova MN, Tseng GC, Steward D, Diorio D, Nikiforov YE. MicroRNA expression profiling of thyroid tumors: biological significance and diagnostic utility. J Clin Endocrinol Metab 2008;93:1600-8.
5. Pallante P, Visone R, Ferracin M, Ferraro A, Berlingieri MT, Troncone G, et al. MicroRNA deregulation in human thyroid papillary carcinomas. Endocr Relat Cancer 2006;13:497-508.
6. Aherne ST, Smyth PC, Flavin RJ, Russell SM, Denning KM, Li JH, et al. Geographical mapping of a multifocal thyroid tumour using genetic alteration analysis & miRNA profiling. Mol Cancer 2008;7:89.
7. Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006;6:857-66.
8. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004;116:281-97.
9. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, et al. MicroRNA expression profiles classify human cancers. Nature 2005;435:834-8.
10. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, et al. MicroRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 2006;103:2257-61.
11. He H, Jazdzewski K, Li W, Liyanarachchi S, Nagy R, Volinia S, et al. The role of microRNA genes in papillary thyroid carcinoma. Proc Natl Acad Sci U S A 2005;102:19075-80.
12. Nikiforova MN, Chiosea SI, Nikiforov YE. MicroRNA expression profiles in thyroid tumors. Endocr Pathol 2009;20:85-91.
13. Nikiforova MN, Nikiforov YE. Molecular genetics of thyroid cancer: implications for diagnosis, treatment and prognosis. Expert Rev Mol Diagn 2008;8:83-95.
14. Tetzlaff MT, Liu A, Xu X, Master SR, Baldwin DA, Tobias JW, et al. Differential expression of miRNAs in papillary thyroid carcinoma compared to multinodular goiter using formalin fixed paraffin embedded tissues. Endocr Pathol 2007;18:163-73.
15. Chen YT, Kitabayashi N, Zhou XH, Fahey TJ 3rd, Scognamiglio T. MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma. Mod Pathol 2008;21:1139-46.
16. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25:402-8.
17. Bewick V, Cheek L, Ball J. Statistics review 14: Logistic regression. Critical Care 2005;9:112-8.
18. Heneghan HM, Miller N, Kelly R, Newell J, Kerin MJ. Systemic miR-195 differentiates breast cancer from other malignancies and is a potential marker for detecting noninvasive and early disease. Oncologist 2010;15:673-82.
19. Barshack I, Lithwick-Yanai G, Afek A, Rosenblatt K, Tabian-Keissar H, Zepeniuk M, et al. MicroRNA expression differentiates between primary lung tumors and metastases to the lung. Pathol Res Pract 2010;206:578-84.
20. Du J, Schageman JJ, Irnov, Girard L, Hammond SM, Minna JD, et al. A MicroRNA expression distinguishes SCLC and NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs. J Exp Clin Cancer Res 2010;29:75.
21. Fridman E, Dotan Z, Barshack I, David BM, Dov A, Tabak S, et al. Accurate Molecular Classification of Renal Tumors Using MicroRNA Expression. J Mol Diagn 2010;12:687-96.
22. Menon MP, Khan A. Micro-RNAs in thyroid neoplasms: molecular, diagnostic and therapeutic implications. J Clin Pathol 2009;62:978-85.
23. Visone R, Pallante P, Vecchione A, Cirombella R, Ferracin M, Ferraro A, et al. Specific microRNAs are downregulated in human thyroid anaplastic carcinomas. Oncogene 2007;26:7590-5.