Autoimmune disease-associated CD226 gene variants are not involved in giant cell arteritis susceptibility in the Spanish population

Clinical and Experimental Rheumatology

Volumn 30, Issue SUPPL. 70, 2012, Pages

  Serrano, Aurora ^a   Carmona, F David ^a   Miranda Filloy, José A ^b   Castañeda, Santos ^c   Rodríguez Rodríguez, Luis ^d   Morado, Inmaculada C ^d   Gómez Vaquero, Carmen ^e   Solans, Roser ^f   Sopeña, Bernardo ^g   Blanco, Ricardo ^h   Unzurrunzaga, Ainhoa ⁱ   Ortego Centeno, Norberto ^j   Marí Alfonso, Begoña ^k   Hidalgo Conde, Ana ^m   de Miguel, Eugenio ^l   Martín, Javier ^a   González Gay, Miguel A ^h  

^a CSIC   (Spain)

^b HOSPITAL XERAL CALDE   (Spain)

^c HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^d HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^e HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^f HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^g UNIVERSITY HOSPITAL COMPLEX OF VIGO   (Spain)

^h HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

ⁱ HOSPITAL DE GALDAKAO   (Spain)

^j HOSPITAL UNIVERSITARIO SAN CECILIO   (Spain)

^k UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^l HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^m HOSPITAL UNIVERSITARIO VIRGEN DE LA VICTORIA   (Spain)

more..

Author keywords

CD226; GCA; Rs34794968; Rs727088; Rs763361; SNP; Temporal arteritis

Indexed keywords

AGED; ALLELE; ARTICLE; AUTOIMMUNE DISEASE; CD226 GENE; CLAUDICATION; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; DNA POLYMORPHISM; ETHNIC GROUP; FEMALE; GENE; GENE FUNCTION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GIANT CELL ARTERITIS; HAPLOTYPE; HEADACHE; HUMAN; ISCHEMIA; MAJOR CLINICAL STUDY; MALE; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PRIORITY JOURNAL; RHEUMATIC POLYMYALGIA; STROKE; TEMPORAL ARTERY; VISUAL IMPAIRMENT;

AGED; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; AUTOIMMUNITY; BIOPSY; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; FEMALE; GENE FREQUENCY; GENETIC TESTING; GIANT CELL ARTERITIS; HAPLOTYPES; HUMANS; MALE; ODDS RATIO; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; REAL-TIME POLYMERASE CHAIN REACTION; RISK ASSESSMENT; RISK FACTORS; SPAIN;

EID: 84863733055     PISSN: 0392856X     EISSN: 1593098X     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. XU Z, JIN B: A novel interface consisting of homologous immunoglobulin superfamily members with multiple functions. Cell Mol Immunol 2010; 7: 11-9.
2. SHERRINGTON PD, SCOTT JL, JIN B et al.: TLiSA1 (PTA1) activation antigen implicated in T cell differentiation and platelet activation is a member of the immunoglobulin superfamily exhibiting distinctive regulation of expression. J Biol Chem 1997; 272: 21735-44.
3. KOJIMA H, KANADA H, SHIMIZU S et al.: CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells. J Biol Chem 2003; 278: 36748-53.
4. SHIBUYA K, SHIRAKAWA J, KAMEYAMA T et al.: CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation. J Exp Med 2003; 198: 1829-39.
5. SHIBUYA A, CAMPBELL D, HANNUM C et al.: DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. Immunity 1996; 4: 573-81.
6. HAFLER JP, MAIER LM, COOPER JD et al.: CD226 Gly307Ser association with multiple autoimmune diseases. Genes Immun 2009; 10: 5-10.
7. TODD JA, WALKER NM, COOPER JD et al.: Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 2007; 39: 857-64.
8. MAITI AK, KIM-HOWARD X, VISWANATHAN P et al.: Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases. Rheumatology 2010; 49: 1239-44.
9. WIECZOREK S, HOFFJAN S, CHAN A et al.: Novel association of the CD226 (DNAM- 1) Gly307Ser polymorphism in Wegener's granulomatosis and confirmation for multiple sclerosis in German patients. Genes Immun 2009; 10: 591-5.
10. DIEUDE P, GUEDJ M, TRUCHETET ME et al.: Association of the CD226 Ser (307) variant with systemic sclerosis: evidence of a contribution of costimulation pathways in systemic sclerosis pathogenesis. Arthritis Rheum 2011; 63: 1097-105.
11. LOFGREN SE, DELGADO-VEGA AM, GALLANT CJ et al.: A 3'-untranslated region variant is associated with impaired expression of CD226 in T and natural killer T cells and is associated with susceptibility to systemic lupus erythematosus. Arthritis Rheum 2010; 62: 3404-14.
12. SALVARANI C, CANTINI F, BOIARDI L, HUNDER GG: Polymyalgia rheumatica and giantcell arteritis. N Engl J Med 2002; 347: 261-71.
13. GONZALEZ-GAY MA, VAZQUEZ-RODRIGUEZ TR, LOPEZ-DIAZ MJ et al.: Epidemiology of giant cell arteritis and polymyalgia rheumatica. Arthritis Rheum 2009; 61: 1454-61.
14. GONZALEZ-GAY MA, GARCIA-PORRUA C: Epidemiology of the vasculitides. Rheum Dis Clin North Am 2001; 27: 729-49.
15. GONZALEZ-GAY MA, MIRANDA-FILLOY JA, LOPEZ-DIAZ MJ et al.: Giant cell arteritis in northwestern Spain: a 25-year epidemiologic study. Medicine (Baltimore). 2007; 86: 61-8.
16. WEYAND CM, MA-KRUPA W, PRYSHCHEP O, GROSCHEL S, BERNARDINO R, GORONZY JJ: Vascular dendritic cells in giant cell arteritis. Ann N Y Acad Sci 2005; 1062: 195-208.
17. WEYAND CM, YOUNGE BR, GORONZY JJ: IFN-gamma and IL-17: the two faces of Tcell pathology in giant cell arteritis. Curr Opin Rheumatol 2011; 23: 43-9.
18. LY KH, REGENT A, TAMBY MC, MOUTHON L: Pathogenesis of giant cell arteritis: More than just an inflammatory condition? Autoimmun Rev 2010; 9: 635-45.
19. ZHERNAKOVA A, VAN DIEMEN CC, WIJMENGA C: Detecting shared pathogenesis from the shared genetics of immune-related diseases. Nat Rev Genet 2009; 10: 43-55.
20. HUNDER GG, BLOCH DA, MICHEL BA et al.: The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis. Arthritis Rheum 1990; 33: 1122-8.
21. GONZALEZ-GAY MA, GARCIA-PORRUA C, LLORCA J, GONZALEZ-LOUZAO C, RODRIGUEZ-LEDO P: Biopsy-negative giant cell arteritis: clinical spectrum and predictive factors for positive temporal artery biopsy. Semin Arthritis Rheum 2001; 30: 249-56.
22. PALOMINO-MORALES R, TORRES O, VAZQUEZ-RODRIGUEZ TR et al.: Association between toll-like receptor 4 gene polymorphism and biopsy-proven giant cell arteritis. J Rheumatol 2009; 36: 1501-6.
23. GONZALEZ-GAY MA, GARCIA-PORRUA C, VAZQUEZ-CARUNCHO M: Polymyalgia rheumatica in biopsy proven giant cell arteritis does not constitute a different subset but differs from isolated polymyalgia rheumatica. J Rheumatol 1998; 25: 1750-5.
24. GONZALEZ-GAY MA, BARROS S, LOPEZ-DIAZ MJ, GARCIA-PORRUA C, SANCHEZ-ANDRADE A, LLORCA J: Giant cell arteritis: disease patterns of clinical presentation in a series of 240 patients. Medicine 2005; 84: 269-76.
25. GONZALEZ-GAY MA, LOPEZ-DIAZ MJ, BARROS S et al.: Giant cell arteritis: laboratory tests at the time of diagnosis in a series of 240 patients. Medicine 2005; 84: 277-90.
26. RUEDA B, LOPEZ-NEVOT M, LOPEZ-DIAZ M et al.: A functional variant of vascular endothelial growth factor is associated with severe ischemic complications in giant cell arteritis. J Rheumatol 2005; 32: 1737-41.
27. SKOL A, SCOTT L, ABECASIS G, BOEHNKE M: Joint analysis is more efficient than replication- based analysis for two-stage genomewide association studies. Nat Genet 2006; 38: 209-13.
28. PURCELL S, NEALE B, TODD-BROWN K et al.: PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81: 559-75.
29. BENJAMINI Y, HOCHBERG Y: Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc B 1995; 57: 289-300.
30. BARRETT JC, FRY B, MALLER J, DALY MJ: Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-5.
31. MAIER LM, HAFLER DA: Autoimmunity risk alleles in costimulation pathways. Immunol Rev 2009; 229: 322-36.
32. WEYAND CM, GORONZY JJ: Giant-cell arteritis and polymyalgia rheumatica. Ann Intern Med 2003; 139: 505-15.
33. DENG J, YOUNGE BR, OLSHEN RA, GORONZY JJ, WEYAND CM: Th17 and Th1 T-cell responses in giant cell arteritis. Circulation 2010; 121: 906-15.
34. OROZCO G, RUEDA B, MARTIN J: Genetic basis of rheumatoid arthritis. Biomed Pharmacother 2006; 60: 656-62.
35. GONZALEZ-GAY MA, AMOLI MM, GARCIAPORRUA C, OLLIER WE: Genetic markers of disease susceptibility and severity in giant cell arteritis and polymyalgia rheumatica. Semin Arthritis Rheum 2003; 33: 38-48.
36. DESHMUKH HA, MAITI AK, KIM-HOWARD XR et al.: Evaluation of 19 Autoimmune Disease- associated Loci with Rheumatoid Arthritis in a Colombian Population: Evidence for Replication and Gene-Gene Interaction. J Rheumatol in press.
37. TAN RJ, GIBBONS LJ, POTTER C et al.: Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment. Ann Rheum Dis 2010; 69: 1029-35.
38. BARTON A, WORTHINGTON J: Genetic susceptibility to rheumatoid arthritis: an emerging picture. Arthritis Rheum 2009; 61: 1441-6.
39. OROZCO G, SANCHEZ E, GONZALEZ-GAY MA et al.: Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus. Arthritis Rheum 2005; 52: 219-24.
40. OROZCO G, ALIZADEH BZ, DELGADO-VEGA AM et al.: Association of STAT4 with rheumatoid arthritis: a replication study in three European populations. Arthritis Rheum 2008; 58: 1974-80.
41. GONZALEZ-GAY MA, OLIVER J, OROZCO G, GARCIA-PORRUA C, LOPEZ-NEVOT MA, MARTIN J: Lack of association of a functional single nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with susceptibility to biopsy-proven giant cell arteritis. J Rheumatol 2005; 32: 1510-2.
42. PALOMINO-MORALES R, VAZQUEZ-RODRIGUEZ TR, MORADO IC et al.: Lack of association between STAT4 gene polymorphism and biopsy-proven giant cell arteritis. J Rheumatol 2009; 36: 1021-5.
43. TORRES O, PALOMINO-MORALES R, VAZQUEZ- RODRIGUEZ TR et al.: Lack of association between TRAF1/C5 gene polymorphisms and biopsy-proven giant cell arteritis. J Rheumatol 2010; 37: 131-5.
44. RODRÍGUEZ-RODRÍGUEZ L, CASTAÑEDA S, VÁZQUEZ-RODRÍGUEZ TR et al.: Role of the rs6822844 gene polymorphism at the IL2- IL21 region in biopsy-proven giant cell arteritis. Clin Exp Rheumatol 2011; 29: 12-6.
45. TORRES O, PALOMINO-MORALES R, VAZQUEZ-RODRIGUEZ T et al.: Lack of association between IFNGR1 gene polymorphisms and biopsy-proven giant cell arteritis. Clin Exp Rheumatol 2010; 28: 31-4.
46. TORRES O, PALOMINO-MORALES R, VAZQUEZ-RODRIGUEZ TR et al.: Lack of association between hypoxia inducible factor-1 alpha gene polymorphisms and biopsy-proven giant cell arteritis. Clin Exp Rheumatol 2010; 28: 40-5.