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Volumn 60, Issue 3, 2012, Pages 191-198

Prostate cancer and immunoproteome: Awakening and reprogramming the guardian angels

Author keywords

DNA damage; Immunoproteome; Major histocompatibility complex proteins; Prostate cancer

Indexed keywords

ATM PROTEIN; ATR PROTEIN; CANCER VACCINE; DNA VACCINE; GAMMA INTERFERON; IMMUNOPROTEOME; MAJOR HISTOCOMPATIBILITY ANTIGEN; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2D; ONCOLYTIC HERPES VIRUS; PEPTIDE VACCINE; PROSTATE STEM CELL ANTIGEN VACCINE; PROTEOME; STEAP[102-116] VACCINE; STEAP[192-206] VACCINE; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84863728588     PISSN: 0004069X     EISSN: 16614917     Source Type: Journal    
DOI: 10.1007/s00005-012-0169-y     Document Type: Review
Times cited : (5)

References (41)
  • 1
    • 79955974536 scopus 로고    scopus 로고
    • DNAM-1 ligand expression on Ag-stimulated T lymphocytes is mediated by ROS-dependent activation of DNA-damage response: Relevance for NK-T cell interaction
    • Ardolino M, Zingoni A, Cerboni C et al (2011) DNAM-1 ligand expression on Ag-stimulated T lymphocytes is mediated by ROS-dependent activation of DNA-damage response: relevance for NK-T cell interaction. Blood 117:4778-4786
    • (2011) Blood , vol.117 , pp. 4778-4786
    • Ardolino, M.1    Zingoni, A.2    Cerboni, C.3
  • 2
    • 77950636009 scopus 로고    scopus 로고
    • Proteasome regulation of ULBP1 transcription
    • Butler JE, Moore MB, Presnell SR et al (2009) Proteasome regulation of ULBP1 transcription. J Immunol 182:6600-6609
    • (2009) J Immunol , vol.182 , pp. 6600-6609
    • Butler, J.E.1    Moore, M.B.2    Presnell, S.R.3
  • 3
    • 79958829840 scopus 로고    scopus 로고
    • 2-microglobulin by pentameric IgM antibodies
    • 2-microglobulin by pentameric IgM antibodies. Br J Haematol 154:111-121
    • (2011) Br J Haematol , vol.154 , pp. 111-121
    • Cao, Y.1    Lan, Y.2    Qian, J.3
  • 4
    • 34447104224 scopus 로고    scopus 로고
    • Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK-cell lysis
    • DOI 10.1182/blood-2006-10-052720
    • Cerboni C, Zingoni A, Cippitelli M et al (2007) Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK-cell lysis. Blood 110:606-615 (Pubitemid 47105399)
    • (2007) Blood , vol.110 , Issue.2 , pp. 606-615
    • Cerboni, C.1    Zingoni, A.2    Cippitelli, M.3    Piccoli, M.4    Frati, L.5    Santoni, A.6
  • 5
    • 48249149168 scopus 로고    scopus 로고
    • The use of chelated radionuclide (samarium-153- ethylenediaminetetramethylenephosphonate) to modulate phenotype of tumor cells and enhance T cell-mediated killing
    • Chakraborty M, Wansley EK, Carrasquillo JA et al (2008) The use of chelated radionuclide (samarium-153-ethylenediaminetetramethylenephosphonate) to modulate phenotype of tumor cells and enhance T cell-mediated killing. Clin Cancer Res 14:4241-4249
    • (2008) Clin Cancer Res , vol.14 , pp. 4241-4249
    • Chakraborty, M.1    Wansley, E.K.2    Carrasquillo, J.A.3
  • 6
    • 80054797849 scopus 로고    scopus 로고
    • Upregulation of NKG2D ligands and enhanced natural killer cell cytotoxicity by hydralazine and valproate
    • Chávez-Blanco A, De la Cruz-Hernández E, Domínguez GI et al (2011) Upregulation of NKG2D ligands and enhanced natural killer cell cytotoxicity by hydralazine and valproate. Int J Oncol 39:1491-1499
    • (2011) Int J Oncol , vol.39 , pp. 1491-1499
    • Chávez-Blanco, A.1    De La Cruz-Hernández, E.2    Domínguez, G.I.3
  • 7
    • 27144517441 scopus 로고    scopus 로고
    • Differential CTLs specific for prostate-specific antigen in healthy donors and patients with prostate cancer
    • DOI 10.1093/intimm/dxh309
    • Elkord E, Williams PE, Kynaston H et al (2005) Differential CTLs specific for prostate-specific antigen in healthy donors and patients with prostate cancer. Int Immunol 17:1315-1325 (Pubitemid 41488005)
    • (2005) International Immunology , vol.17 , Issue.10 , pp. 1315-1325
    • Elkord, E.1    Williams, P.E.2    Kynaston, H.3    Rowbottom, A.W.4
  • 8
    • 49649129991 scopus 로고    scopus 로고
    • Targeting TARP, a novel breast and prostate tumor-associated antigen, with T cell receptor-like human recombinant antibodies
    • Epel M, Carmi I, Soueid-Baumgarten S et al (2008) Targeting TARP, a novel breast and prostate tumor-associated antigen, with T cell receptor-like human recombinant antibodies. Eur J Immunol 38:1706-1720
    • (2008) Eur J Immunol , vol.38 , pp. 1706-1720
    • Epel, M.1    Carmi, I.2    Soueid-Baumgarten, S.3
  • 9
    • 79952380566 scopus 로고    scopus 로고
    • Effective targeting of prostate cancer by lymphocytes redirected by a PSMA × CD3 bispecific single-chain diabody
    • Fortmüller K, Alt K, Gierschner D et al (2011) Effective targeting of prostate cancer by lymphocytes redirected by a PSMA × CD3 bispecific single-chain diabody. Prostate 71:588-596
    • (2011) Prostate , vol.71 , pp. 588-596
    • Fortmüller, K.1    Alt, K.2    Gierschner, D.3
  • 10
    • 70449334513 scopus 로고    scopus 로고
    • Bacillus Calmette-Guérin cell-wall skeleton enhances the killing activity of cytotoxic lymphocyte-activated human dendritic cells transduced with the prostate-specific antigen gene
    • Fujii R, Iwahashi M, Kikkawa K et al (2009) Bacillus Calmette- Guérin cell-wall skeleton enhances the killing activity of cytotoxic lymphocyte-activated human dendritic cells transduced with the prostate-specific antigen gene. BJU Int 104:1766-1773
    • (2009) BJU Int , vol.104 , pp. 1766-1773
    • Fujii, R.1    Iwahashi, M.2    Kikkawa, K.3
  • 11
    • 38849142632 scopus 로고    scopus 로고
    • Prostate stem cell antigen vaccination induces a long-term protective immune response against prostate cancer in the absence of autoimmunity
    • DOI 10.1158/0008-5472.CAN-07-0445
    • Garcia-Hernandez Mde L, Gray A, Hubby B et al (2008) Prostate stem cell antigen vaccination induces a long-term protective immune response against prostate cancer in the absence of autoimmunity. Cancer Res 68:861-869 (Pubitemid 351206764)
    • (2008) Cancer Research , vol.68 , Issue.3 , pp. 861-869
    • Garcia-Hernandez, M.D.L.L.1    Gray, A.2    Hubby, B.3    Klinger, O.J.4    Kast, W.M.5
  • 12
    • 41549163195 scopus 로고    scopus 로고
    • NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy
    • Guerra N, Tan YX, Joncker NT et al (2008) NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity 28:571-580
    • (2008) Immunity , vol.28 , pp. 571-580
    • Guerra, N.1    Tan, Y.X.2    Joncker, N.T.3
  • 13
    • 32944476689 scopus 로고    scopus 로고
    • Forcing tumor cells to present their own tumor antigens to the immune system: A necessary design for an efficient tumor immunotherapy
    • Humphreys RE, Hillman GG, von Hofe E et al (2004) Forcing tumor cells to present their own tumor antigens to the immune system: a necessary design for an efficient tumor immunotherapy. Cell Mol Immunol 1:180-185
    • (2004) Cell Mol Immunol , vol.1 , pp. 180-185
    • Humphreys, R.E.1    Hillman, G.G.2    Von Hofe, E.3
  • 14
    • 79958733649 scopus 로고    scopus 로고
    • Induction of in vitro and in vivo NK cell cytotoxicity using high-avidity immunoligands targeting prostate-specific membrane antigen in prostate carcinoma
    • Jachimowicz RD, Fracasso G, Yazaki PJ et al (2011) Induction of in vitro and in vivo NK cell cytotoxicity using high-avidity immunoligands targeting prostate-specific membrane antigen in prostate carcinoma. Mol Cancer Ther 10:1036-1045
    • (2011) Mol Cancer Ther , vol.10 , pp. 1036-1045
    • Jachimowicz, R.D.1    Fracasso, G.2    Yazaki, P.J.3
  • 15
    • 80052358187 scopus 로고    scopus 로고
    • Lactobacilli secreting a tumor antigen and IL-15 activates neutrophils and dendritic cells and generates cytotoxic T lymphocytes against cancer cells
    • Kandasamy M, Bay BH, Lee YK et al (2011) Lactobacilli secreting a tumor antigen and IL-15 activates neutrophils and dendritic cells and generates cytotoxic T lymphocytes against cancer cells. Cell Immunol 271:89-96
    • (2011) Cell Immunol , vol.271 , pp. 89-96
    • Kandasamy, M.1    Bay, B.H.2    Lee, Y.K.3
  • 16
    • 67049155480 scopus 로고    scopus 로고
    • Vaccination with recombinant adenoviruses and dendritic cells expressing prostate-specific antigens is effective in eliciting CTL and suppresses tumor growth in the experimental prostate cancer
    • Kim S, Lee JB, Lee GK et al (2009) Vaccination with recombinant adenoviruses and dendritic cells expressing prostate-specific antigens is effective in eliciting CTL and suppresses tumor growth in the experimental prostate cancer. Prostate 69:938-948
    • (2009) Prostate , vol.69 , pp. 938-948
    • Kim, S.1    Lee, J.B.2    Lee, G.K.3
  • 17
    • 63149091820 scopus 로고    scopus 로고
    • Cutting edge: Permissive MHC class II allele changes the pattern of antitumor immune response resulting in failure of tumor rejection
    • Klyushnenkova EN, Kouiavskaia DV, Berard CA et al (2009) Cutting edge: permissive MHC class II allele changes the pattern of antitumor immune response resulting in failure of tumor rejection. J Immunol 182:1242-1246
    • (2009) J Immunol , vol.182 , pp. 1242-1246
    • Klyushnenkova, E.N.1    Kouiavskaia, D.V.2    Berard, C.A.3
  • 18
    • 34347210340 scopus 로고    scopus 로고
    • Recognition of prostate and melanoma tumor cells by six-transmembrane epithelial antigen of prostate-specific helper T lymphocytes in a human leukocyte antigen class II-restricted manner
    • DOI 10.1158/0008-5472.CAN-07-0304
    • Kobayashi H, Nagato T, Sato K et al (2007) Recognition of prostate and melanoma tumor cells by six-transmembrane epithelial antigen of prostate-specific helper T lymphocytes in a human leukocyte antigen class II-restricted manner. Cancer Res 67:5498-5504 (Pubitemid 46997291)
    • (2007) Cancer Research , vol.67 , Issue.11 , pp. 5498-5504
    • Kobayashi, H.1    Nagato, T.2    Sato, K.3    Aoki, N.4    Kimura, S.5    Murakami, M.6    Iizuka, H.7    Azumi, M.8    Kakizaki, H.9    Tateno, M.10    Celis, E.11
  • 19
    • 77952466558 scopus 로고    scopus 로고
    • Anti-tumor immune response induced by dendritic cells transduced with truncated PSMA IRES 4-1BBL recombinant adenoviruses
    • Kuang Y, Weng X, Liu X et al (2010) Anti-tumor immune response induced by dendritic cells transduced with truncated PSMA IRES 4-1BBL recombinant adenoviruses. Cancer Lett 293: 254-262
    • (2010) Cancer Lett , vol.293 , pp. 254-262
    • Kuang, Y.1    Weng, X.2    Liu, X.3
  • 20
    • 79956140723 scopus 로고    scopus 로고
    • Development of an MHC class i L(d)-restricted PSA peptide-loaded tetramer for detection of PSA-specific CD8 ? T cells in the mouse
    • Lemke CD, Graham JB, Lubaroff DM et al (2011) Development of an MHC class I L(d)-restricted PSA peptide-loaded tetramer for detection of PSA-specific CD8 ? T cells in the mouse. Prostate Cancer Prostatic Dis 14:118-121
    • (2011) Prostate Cancer Prostatic Dis , vol.14 , pp. 118-121
    • Lemke, C.D.1    Graham, J.B.2    Lubaroff, D.M.3
  • 21
    • 80053436546 scopus 로고    scopus 로고
    • Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2
    • Li H, Lakshmikanth T, Garofalo C et al (2011) Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2. Cell Cycle 10:3346-3358
    • (2011) Cell Cycle , vol.10 , pp. 3346-3358
    • Li, H.1    Lakshmikanth, T.2    Garofalo, C.3
  • 22
    • 77949615011 scopus 로고    scopus 로고
    • Hydroxyurea upregulates NKG2D ligand expression in myeloid leukemia cells synergistically with valproic acid and potentially enhances susceptibility of leukemic cells to natural killer cell-mediated cytolysis
    • Lu X, Ohata K, Kondo Y et al (2010) Hydroxyurea upregulates NKG2D ligand expression in myeloid leukemia cells synergistically with valproic acid and potentially enhances susceptibility of leukemic cells to natural killer cell-mediated cytolysis. Cancer Sci 101:609-615
    • (2010) Cancer Sci , vol.101 , pp. 609-615
    • Lu, X.1    Ohata, K.2    Kondo, Y.3
  • 23
    • 34447643995 scopus 로고    scopus 로고
    • Generation of robust cytotoxic T lymphocytes against prostate specific antigen by transduction of dendritic cells using protein and recombinant adeno-associated virus
    • DOI 10.1007/s00262-007-0307-2
    • Mahadevan M, Liu Y, YouCet al (2007) Generation of robust cytotoxic T lymphocytes against prostate specific antigen by transduction of dendritic cells using protein and recombinant adeno-associated virus. Cancer Immunol Immunother 56:1615-1624 (Pubitemid 47094391)
    • (2007) Cancer Immunology, Immunotherapy , vol.56 , Issue.10 , pp. 1615-1624
    • Mahadevan, M.1    Liu, Y.2    You, C.3    Luo, R.4    You, H.5    Mehta, J.L.6    Hermonat, P.L.7
  • 24
    • 79959566609 scopus 로고    scopus 로고
    • SIGLEC12, a humanspecific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomas
    • Mitra N, Banda K, Altheide TK et al (2011) SIGLEC12, a humanspecific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomas. J Biol Chem 286:23003-23011
    • (2011) J Biol Chem , vol.286 , pp. 23003-23011
    • Mitra, N.1    Banda, K.2    Altheide, T.K.3
  • 25
    • 33748345175 scopus 로고    scopus 로고
    • MHC class I and class II molecules are expressed in both human and mouse prostate tumor microenvironment
    • DOI 10.1002/pros.20432
    • Nanda NK, Birch L, Greenberg NM et al (2006) MHC class I and class II molecules are expressed in both human and mouse prostate tumor microenvironment. Prostate 66:1275-1284 (Pubitemid 44384304)
    • (2006) Prostate , vol.66 , Issue.12 , pp. 1275-1284
    • Nanda, N.K.1    Birch, L.2    Greenberg, N.M.3    Prins, G.S.4
  • 26
    • 77953291273 scopus 로고    scopus 로고
    • Tumor cells infected with oncolytic influenza A virus prime natural killer cells for lysis of resistant tumor cells
    • Ogbomo H, Michaelis M, Geiler J et al (2010) Tumor cells infected with oncolytic influenza A virus prime natural killer cells for lysis of resistant tumor cells. Med Microbiol Immunol 199:93-101
    • (2010) Med Microbiol Immunol , vol.199 , pp. 93-101
    • Ogbomo, H.1    Michaelis, M.2    Geiler, J.3
  • 27
    • 80053576818 scopus 로고    scopus 로고
    • Targeting 4-1BB costimulation to disseminated tumor lesions with bi-specific oligonucleotide aptamers
    • Pastor F, Kolonias D, McNamara JO II et al (2011) Targeting 4-1BB costimulation to disseminated tumor lesions with bi-specific oligonucleotide aptamers. Mol Ther 19:1878-1886
    • (2011) Mol Ther , vol.19 , pp. 1878-1886
    • Pastor, F.1    Kolonias, D.2    McNamara II, J.O.3
  • 28
    • 33947263159 scopus 로고    scopus 로고
    • Attenuation of the glucocorticoid response during Ad5iL-12 adenovirus vector treatment enhances natural killer cell-mediated killing of MHC class I-negative LNCaP prostate tumors
    • DOI 10.1158/0008-5472.CAN-06-3399
    • Raja Gabaglia C, Diaz de Durana Y, Graham FL et al (2007) Attenuation of the glucocorticoid response during Ad5IL-12 adenovirus vector treatment enhances natural killer cell-mediated killing of MHC class I-negative LNCaP prostate tumors. Cancer Res 67:2290-2297 (Pubitemid 46424249)
    • (2007) Cancer Research , vol.67 , Issue.5 , pp. 2290-2297
    • Gabaglia, C.R.1    De Durana, Y.D.2    Graham, F.L.3    Gauldie, J.4    Sercarz, E.E.5    Braciak, T.A.6
  • 29
    • 20444482839 scopus 로고    scopus 로고
    • Recognition of six-transmembrane epithelial antigen of the prostate-expressing tumor cells by peptide antigen-induced cytotoxic T lymphocytes
    • DOI 10.1158/1078-0432.CCR-04-2235
    • Rodeberg DA, Nuss RA, Elsawa SF et al (2005) Recognition of sixtransmembrane epithelial antigen of the prostate-expressing tumor cells by peptide antigen-induced cytotoxic T lymphocytes. Clin Cancer Res 11:4545-4552 (Pubitemid 40825645)
    • (2005) Clinical Cancer Research , vol.11 , Issue.12 , pp. 4545-4552
    • Rodeberg, D.A.1    Nuss, R.A.2    Elsawa, S.F.3    Celis, E.4
  • 30
    • 80155131086 scopus 로고    scopus 로고
    • Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer
    • Smith HA, Cronk RJ, Lang JM et al (2011) Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer. Cancer Res 71:6785-6795
    • (2011) Cancer Res , vol.71 , pp. 6785-6795
    • Smith, H.A.1    Cronk, R.J.2    Lang, J.M.3
  • 31
    • 65349131915 scopus 로고    scopus 로고
    • ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype
    • Soriani A, Zingoni A, Cerboni C et al (2009) ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype. Blood 113:3503-3511
    • (2009) Blood , vol.113 , pp. 3503-3511
    • Soriani, A.1    Zingoni, A.2    Cerboni, C.3
  • 32
    • 80054052507 scopus 로고    scopus 로고
    • Tumor growth and metastasis suppression by Glipr1 gene-modified macrophages in a metastatic prostate cancer model
    • Tabata K, Kurosaka S, Watanabe M et al (2011) Tumor growth and metastasis suppression by Glipr1 gene-modified macrophages in a metastatic prostate cancer model. Gene Ther 18:969-978
    • (2011) Gene Ther , vol.18 , pp. 969-978
    • Tabata, K.1    Kurosaka, S.2    Watanabe, M.3
  • 33
    • 43049154824 scopus 로고    scopus 로고
    • Induction of MHC class I-related chain B (MICB) by 5-aza-20-deoxycytidine
    • Tang KF, He CX, Zeng GL et al (2008a) Induction of MHC class I-related chain B (MICB) by 5-aza-20-deoxycytidine. Biochem Biophys Res Commun 370:578-583
    • (2008) Biochem Biophys Res Commun , vol.370 , pp. 578-583
    • Tang, K.F.1    He, C.X.2    Zeng, G.L.3
  • 34
    • 48249153779 scopus 로고    scopus 로고
    • Decreased dicer expression elicits DNA damage and up-regulation of MICA and MICB
    • Tang KF, Ren H, Cao J et al (2008b) Decreased dicer expression elicits DNA damage and up-regulation of MICA and MICB. J Cell Biol 182:233-239
    • (2008) J Cell Biol , vol.182 , pp. 233-239
    • Tang, K.F.1    Ren, H.2    Cao, J.3
  • 35
    • 77951621656 scopus 로고    scopus 로고
    • Tumor specific cytotoxicity and telomerase down-regulation in prostate cancer by autologous dendritic cells loaded with whole tumor cell antigens
    • Turkeri L, Onol FF, Ozyurek M (2010) Tumor specific cytotoxicity and telomerase down-regulation in prostate cancer by autologous dendritic cells loaded with whole tumor cell antigens. Urol Oncol 28:290-295
    • (2010) Urol Oncol , vol.28 , pp. 290-295
    • Turkeri, L.1    Onol, F.F.2    Ozyurek, M.3
  • 36
    • 32844475008 scopus 로고    scopus 로고
    • Enhanced therapeutic efficacy of IL-12, but not GM-CSF, expressing oncolytic herpes simplex virus for transgenic mouse derived prostate cancers
    • DOI 10.1038/sj.cgt.7700900, PII 7700900
    • Varghese S, Rabkin SD, Liu R et al (2006) Enhanced therapeutic efficacy of IL-12, but not GM-CSF, expressing oncolytic herpes simplex virus for transgenic mouse derived prostate cancers. Cancer Gene Ther 13:253-265 (Pubitemid 43255762)
    • (2006) Cancer Gene Therapy , vol.13 , Issue.3 , pp. 253-265
    • Varghese, S.1    Rabkin, S.D.2    Liu, R.3    Nielsen, P.G.4    Ipe, T.5    Martuza, R.L.6
  • 37
    • 79960726153 scopus 로고    scopus 로고
    • DNA fusion gene vaccines induce cytotoxic T-cell attack on naturally processed peptides of human prostate-specific membrane antigen
    • Vittes GE, Harden EL, Ottensmeier CH et al (2011) DNA fusion gene vaccines induce cytotoxic T-cell attack on naturally processed peptides of human prostate-specific membrane antigen. Eur J Immunol 41:2447-2456
    • (2011) Eur J Immunol , vol.41 , pp. 2447-2456
    • Vittes, G.E.1    Harden, E.L.2    Ottensmeier, C.H.3
  • 39
    • 59449091648 scopus 로고    scopus 로고
    • Obstructing shedding of the immunostimulatory MHC class i chain-related gene B prevents tumor formation
    • Wu JD, Atteridge CL, Wang X et al (2009a) Obstructing shedding of the immunostimulatory MHC class I chain-related gene B prevents tumor formation. Clin Cancer Res 15:632-640
    • (2009) Clin Cancer Res , vol.15 , pp. 632-640
    • Wu, J.D.1    Atteridge, C.L.2    Wang, X.3
  • 40
    • 77958180004 scopus 로고    scopus 로고
    • Up-regulation of major histocompatibility complex class I-related molecules A (MICA) induced by 5-aza-2′-deoxycytidine
    • Wu JF, Zeng GL, Shen W et al (2009b) Up-regulation of major histocompatibility complex class I-related molecules A (MICA) induced by 5-aza-2′-deoxycytidine. Zhonghua Gan Zang Bing Za Zhi 17:675-678
    • (2009) Zhonghua Gan Zang Bing Za Zhi , vol.17 , pp. 675-678
    • Wu, J.F.1    Zeng, G.L.2    Shen, W.3
  • 41
    • 34548059162 scopus 로고    scopus 로고
    • + tumors growth in mice
    • DOI 10.1002/jgm.1067
    • Zhang X, Yu C, Zhao J et al (2007) Vaccination with a DNA vaccine based on human PSCA and HSP70 adjuvant enhances the antigen-specific CD8 + T-cell response and inhibits the PSCA ? tumors growth in mice. J Gene Med 9:715-726 (Pubitemid 47288829)
    • (2007) Journal of Gene Medicine , vol.9 , Issue.8 , pp. 715-726
    • Zhang, X.1    Yu, C.2    Zhao, J.3    Fu, L.4    Yi, S.5    Liu, S.6    Yu, T.7    Chen, W.8


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