Caudate gray matter volume in obsessive-compulsive disorder is influenced by adverse childhood experiences and ongoing drug treatment

Journal of Clinical Psychopharmacology

Volumn 32, Issue 4, 2012, Pages 544-547

  Benedetti, Francesco ^a   Poletti, Sara ^a   Radaelli, Daniele ^a   Pozzi, Elena ^a   Giacosa, Chiara ^a   Ruffini, Chiara ^a   Falini, Andrea ^a   Smeraldi, Enrico ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

Antiobsessive medication; Caudate nucleus; Childhood trauma; Handedness; Obsessive compulsive disorder

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CLOMIPRAMINE; FLUVOXAMINE; SERTRALINE;

ADULT; ADVERSE CHILDHOOD EXPERIENCE; ARTICLE; BRAIN METABOLISM; BRAIN SIZE; CAUDATE GREY MATTER VOLUME; CHILDHOOD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; DSM-IV; FEMALE; HANDEDNESS; HUMAN; IMAGE ANALYSIS; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; OBSESSIVE COMPULSIVE DISORDER; ONSET AGE; OUTCOME ASSESSMENT; PERSONAL EXPERIENCE; PRIORITY JOURNAL; PSYCHIATRIC DIAGNOSIS; PSYCHOPHARMACOTHERAPY; VOXEL BASED MORPHOMETRY;

ADULT; ADULT SURVIVORS OF CHILD ABUSE; AGE OF ONSET; ANTIDEPRESSIVE AGENTS; CAUDATE NUCLEUS; FEMALE; FUNCTIONAL LATERALITY; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NERVE FIBERS, UNMYELINATED; NEUROIMAGING; OBSESSIVE-COMPULSIVE DISORDER;

EID: 84863720691     PISSN: 02710749     EISSN: 1533712X     Source Type: Journal    
DOI: 10.1097/JCP.0b013e31825cce05     Document Type: Article

References (33)

1. Wermter AK, Laucht M, Schimmelmann BG, et al. From nature versus nurture, via nature and nurture, to gene-environment interaction in mental disorders. Eur Child Adolesc Psychiatry. 2010;19:199-210.
2. Rutter M. The interplay of nature, nurture, and developmental influences: the challenge ahead for mental health. Arch Gen Psychiatry. 2002;59:996-1000. (Pubitemid 35291119)
3. Edwards VJ, Holden GW, Felitti VJ, et al. Relationship between multiple forms of childhood maltreatment and adult mental health in community respondents: results from the adverse childhood experiences study. Am J Psychiatry. 2003;160:1453-1460. (Pubitemid 41070921)
4. Feder A, Nestler EJ, Charney DS. Psychobiology and molecular genetics of resilience. Nat Rev Neurosci. 2009;10:446-457.
5. Taylor SE, Eisenberger NI, Saxbe D, et al. Neural responses to emotional stimuli are associated with childhood family stress. Biol Psychiatry. 2006;60:296-301. (Pubitemid 44093442)
6. Benedetti F, Radaelli D, Poletti S, et al. Emotional reactivity in chronic schizophrenia: structural and functional brain correlates and the influence of adverse childhood experiences. Psychol Med. 2011;41:509-519.
7. Felitti VJ, Anda RF, Nordenberg D, et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study. Am J Prev Med. 1998;14:245-258.
8. Moffitt TE, Caspi A, Rutter M. Strategy for investigating interactions between measured genes and measured environments. Arch Gen Psychiatry. 2005;62:473-481. (Pubitemid 40637222)
9. Stein MB, Walker JR, Anderson G, et al. Childhood physical and sexual abuse in patients with anxiety disorders and in a community sample. Am J Psychiatry. 1996;153:275-277. (Pubitemid 26038976)
10. Lochner C, du Toit PL, Zungu-Dirwayi N, et al. Childhood trauma in obsessive-compulsive disorder, trichotillomania, and controls. Depress Anxiety. 2002;15:66-68. (Pubitemid 34252246)
11. Landau D, Iervolino AC, Pertusa A, et al. Stressful life events and material deprivation in hoarding disorder. J Anxiety Disord. 2011;25:192-202.
12. Lochner C, Seedat S, Hemmings SM, et al. Dissociative experiences in obsessive-compulsive disorder and trichotillomania: clinical and genetic findings. Compr Psychiatry. 2004;45:384-391. (Pubitemid 39140892)
13. Mathews CA, Kaur N, Stein MB. Childhood trauma and obsessive-compulsive symptoms. Depress Anxiety. 2008;25:742-751.
14. Chamberlain SR, Blackwell AD, Fineberg NA, et al. The neuropsychology of obsessive compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers. Neurosci Biobehav Rev. 2005;29:399-419. (Pubitemid 40488206)
15. Taylor SE, Lerner JS, Sage RM, et al. Early environment, emotions, responses to stress, and health. J Pers. 2004;72:1365-1393. (Pubitemid 39558089)
16. Goodman WK, Price LH, Rasmussen SA, et al. The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability. Arch Gen Psychiatry. 1989;46:1006-1011. (Pubitemid 19278229)
17. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 1971;9:97-113.
18. Ashburner J, Friston KJ. Unified segmentation. Neuroimage. 2005;26:839-851. (Pubitemid 40825026)
19. Good CD, Johnsrude IS, Ashburner J, et al. Avoxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage. 2001;14:21-36. (Pubitemid 32552740)
20. Grahn JA, Parkinson JA, Owen AM. The cognitive functions of the caudate nucleus. Prog Neurobiol. 2008;86:141-155.
21. Schultz W. Multiple reward signals in the brain. Nat Rev Neurosci. 2000;1:199-207.
22. Scarone S, Colombo C, Livian S, et al. Increased right caudate nucleus size in obsessive-compulsive disorder: detection with magnetic resonance imaging. Psychiatry Res. 1992;45:115-121.
23. Radua J, Mataix-Cols D. Voxel-wise meta-analysis of grey matter changes in obsessive-compulsive disorder. Br J Psychiatry. 2009;195:393-402.
24. Honea R, Crow TJ, Passingham D, et al. Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studies. Am J Psychiatry. 2005;162:2233-2245. (Pubitemid 41740200)
25. van den Heuvel OA, Veltman DJ, Groenewegen HJ, et al. Frontal-striatal dysfunction during planning in obsessive-compulsive disorder. Arch Gen Psychiatry. 2005;62:301-309.
26. Remijnse PL, Nielen MM, van Balkom AJ, et al. Reduced orbitofrontal-striatal activity on a reversal learning task in obsessive-compulsive disorder. Arch Gen Psychiatry. 2006;63: 1225-1236. (Pubitemid 44708081)
27. El Mansari M, Blier P. Mechanisms of action of current and potential pharmacotherapies of obsessive-compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2006;30:362-373. (Pubitemid 43841738)
28. Linden DE. How psychotherapy changes the brainVthe contribution of functional neuroimaging. Mol Psychiatry. 2006;11:528-538.
29. Crowe RR, Smouse PE. The genetic implications of age-dependent penetrance in manic-depressive illness. J Psychiatr Res. 1977;13:273-285. (Pubitemid 8256065)
30. Anda RF, Brown DW, Felitti VJ, et al. Adverse childhood experiences and prescribed psychotropic medications in adults. Am J Prev Med. 2007;32:389-394. (Pubitemid 46660441)
31. Chemtob CM, Wang Y, Dugan KL, et al. Mixed lateral preference and peritraumatic reactions to the World Trade Center attacks. J Nerv Ment Dis. 2006;194:874-876. (Pubitemid 44747912)
32. Spivak B, Segal M, Mester R, et al. Lateral preference in post-traumatic stress disorder. Psychol Med. 1998;28:229-232. (Pubitemid 28043586)
33. Saltzman KM, Weems CF, Reiss AL, et al. Mixed lateral preference in posttraumatic stress disorder. J Nerv Ment Dis. 2006;194:142-144. (Pubitemid 43260197)