-
1
-
-
38649124680
-
Modeling the impact of treatment and screening on U.S. Breast cancer mortality: A Bayesian approach
-
Berry DA, et al. Modeling the impact of treatment and screening on U.S. breast cancer mortality: A Bayesian approach. J Natl Cancer Inst Monogr, 2006 (36): P. 30-6.
-
(2006)
J Natl Cancer Inst Monogr
, Issue.36
, pp. 30-36
-
-
Berry, D.A.1
-
2
-
-
27244434470
-
Effect of screening and adjuvant therapy on mortality from breast cancer
-
Berry DA, et al. Effect of screening and adjuvant therapy on mortality from breast cancer. N Engl J Med. 2005;353(17):1784-92.
-
(2005)
N Engl J Med.
, vol.353
, Issue.17
, pp. 1784-1792
-
-
Berry, D.A.1
-
4
-
-
66249091930
-
The HER-2 receptor and breast cancer: Ten years of targeted anti-HER-2 therapy and personalized medicine
-
Ross JS, et al. The HER-2 receptor and breast cancer: Ten years of targeted anti-HER-2 therapy and personalized medicine. Oncologist. 2009;14 (4):320-68.
-
(2009)
Oncologist.
, vol.14
, Issue.4
, pp. 320-368
-
-
Ross, J.S.1
-
5
-
-
0024337144
-
Studies of the HER-2/neu protooncogene in human breast and ovarian cancer
-
Slamon DJ, et al. Studies of the HER-2/neu protooncogene in human breast and ovarian cancer. Science. 1989;244(4905):707-12.
-
(1989)
Science.
, vol.244
, Issue.4905
, pp. 707-712
-
-
Slamon, D.J.1
-
6
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, et al. Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science. 1987;235(4785):177-82.
-
(1987)
Science.
, vol.235
, Issue.4785
, pp. 177-182
-
-
Slamon, D.J.1
-
7
-
-
33847147313
-
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
-
Wolff AC, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol. 2007;25(1):118-45.
-
(2007)
J Clin Oncol.
, vol.25
, Issue.1
, pp. 118-145
-
-
Wolff, A.C.1
-
8
-
-
79957492068
-
Clinical Notice for American Society of Clinical Oncology-College of American Pathologists guideline recommendations on ER/PgR and HER2 testing in breast cancer
-
Appropriate ER/PR and HER2 testing is the first step in the proper management of breast cancer patients. The Clinical Notice reconciles ER/PR and HER2 testing recommendations
-
Hammond ME, Hayes DF, Wolff AC. Clinical Notice for American Society of Clinical Oncology-College of American Pathologists guideline recommendations on ER/PgR and HER2 testing in breast cancer. J Clin Oncol. 2011;29(15):e458. Appropriate ER/PR and HER2 testing is the first step in the proper management of breast cancer patients. The Clinical Notice reconciles ER/PR and HER2 testing recommendations.
-
(2011)
J Clin Oncol.
, vol.29
, Issue.15
-
-
Hammond, M.E.1
Hayes, D.F.2
Wolff, A.C.3
-
9
-
-
0037440261
-
Quantitative association between HER-2/neu and steroid hormone receptors in hormone receptor-positive primary breast cancer
-
Konecny G, et al. Quantitative association between HER-2/neu and steroid hormone receptors in hormone receptor-positive primary breast cancer. J Natl Cancer Inst. 2003;95(2):142-53.
-
(2003)
J Natl Cancer Inst.
, vol.95
, Issue.2
, pp. 142-153
-
-
Konecny, G.1
-
10
-
-
0035863383
-
Response to cyclophosphamide, methotrexate, and fluorouracil in lymph node-positive breast cancer according to HER2 overexpression and other tumor biologic variables
-
Menard S, et al. Response to cyclophosphamide, methotrexate, and fluorouracil in lymph node-positive breast cancer according to HER2 overexpression and other tumor biologic variables. J Clin Oncol. 2001;19(2):329-35.
-
(2001)
J Clin Oncol.
, vol.19
, Issue.2
, pp. 329-335
-
-
Menard, S.1
-
11
-
-
0032538050
-
ErbB-2, p53, and efficacy of adjuvant therapy in lymph node-positive breast cancer
-
Thor AD, et al. erbB-2, p53, and efficacy of adjuvant therapy in lymph node-positive breast cancer. J Natl Cancer Inst. 1998;90(18):1346-60.
-
(1998)
J Natl Cancer Inst.
, vol.90
, Issue.18
, pp. 1346-1360
-
-
Thor, A.D.1
-
12
-
-
33646681444
-
HER2 and responsiveness of breast cancer to adjuvant chemotherapy
-
Pritchard KI, et al. HER2 and responsiveness of breast cancer to adjuvant chemotherapy. N Engl J Med. 2006;354(20):2103-11.
-
(2006)
N Engl J Med.
, vol.354
, Issue.20
, pp. 2103-2111
-
-
Pritchard, K.I.1
-
13
-
-
3843120055
-
Correlation between complete response to anthracycline-based chemotherapy and topoisomerase II-Alpha gene amplification and protein overexpression in locally advanced/metastatic breast cancer
-
Cardoso F, et al. Correlation between complete response to anthracycline-based chemotherapy and topoisomerase II-Alpha gene amplification and protein overexpression in locally advanced/metastatic breast cancer. Int J Oncol. 2004;24(1):201-9.
-
(2004)
Int J Oncol.
, vol.24
, Issue.1
, pp. 201-209
-
-
Cardoso, F.1
-
14
-
-
33746746400
-
TOP2A and HER2 gene amplification as predictors of response to anthracycline treatment in breast cancer
-
Villman K, et al. TOP2A and HER2 gene amplification as predictors of response to anthracycline treatment in breast cancer. Acta Oncol. 2006;45(5):590-6.
-
(2006)
Acta Oncol.
, vol.45
, Issue.5
, pp. 590-596
-
-
Villman, K.1
-
15
-
-
4444320915
-
Her-2/neu gene amplification and response to paclitaxel in patients withmetastatic breast cancer
-
Konecny GE, et al. Her-2/neu gene amplification and response to paclitaxel in patients withmetastatic breast cancer. J Natl Cancer Inst. 2004;96(15):1141-51.
-
(2004)
J Natl Cancer Inst.
, vol.96
, Issue.15
, pp. 1141-1151
-
-
Konecny, G.E.1
-
16
-
-
35248895346
-
HER2 and response to paclitaxel in node-positive breast cancer
-
Hayes DF, et al. HER2 and response to paclitaxel in node-positive breast cancer. N Engl J Med. 2007;357 (15):1496-506.
-
(2007)
N Engl J Med.
, vol.357
, Issue.15
, pp. 1496-1506
-
-
Hayes, D.F.1
-
17
-
-
80052728749
-
Four-year follow-up of trastuzumab plus adjuvant chemotherapy for operable human epidermal growth factor receptor 2-positive breast cancer: Joint analysis of data from NCCTGN9831 and NSABP B-31
-
This joint analysis of randomized NSABP B-31 and NCCTG N9831 showed improvement in DFS and OS in patients with HER2-positive breast cancer who received trastuzumab with anthracycline-based chemotherapy in adjuvant setting. These data provided support for use of trastuzumab as standard of care in adjuvant setting for patients with HER2-positive tumors 91cm
-
Perez EA, et al. Four-year follow-up of trastuzumab plus adjuvant chemotherapy for operable human epidermal growth factor receptor 2-positive breast cancer: Joint analysis of data from NCCTGN9831 and NSABP B-31. J Clin Oncol. 2011;29(25):3366-73. This joint analysis of randomized NSABP B-31 and NCCTG N9831 showed improvement in DFS and OS in patients with HER2-positive breast cancer who received trastuzumab with anthracycline-based chemotherapy in adjuvant setting. These data provided support for use of trastuzumab as standard of care in adjuvant setting for patients with HER2-positive tumors 91cm.
-
(2011)
J Clin Oncol.
, vol.29
, Issue.25
, pp. 3366-3373
-
-
Perez, E.A.1
-
18
-
-
79952041937
-
Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: A 4-year follow-up of a randomised controlled trial
-
In contrast to NSABP B-31 and NCCTG N9831, in HERA trial patients who completed adjuvant chemotherapy and radiation therapy, were randomized to trastuzumab for one or two years, or no additional therapy. Patients on arm treated with trastuzumab for one year had significantly improved DFS compared with arm without trastuzumab
-
Gianni L, et al. Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: A 4-year follow-up of a randomised controlled trial. Lancet Oncol. 2011;12(3):236-44. In contrast to NSABP B-31 and NCCTG N9831, in HERA trial patients who completed adjuvant chemotherapy and radiation therapy, were randomized to trastuzumab for one or two years, or no additional therapy. Patients on arm treated with trastuzumab for one year had significantly improved DFS compared with arm without trastuzumab.
-
(2011)
Lancet Oncol.
, vol.12
, Issue.3
, pp. 236-244
-
-
Gianni, L.1
-
19
-
-
80053539103
-
Adjuvant trastuzumab in HER2-positive breast cancer
-
Results from this randomized trial indicate that trastuzumab plus non-Anthracycline chemotherapy is reasonable and effective alternative to anthracycline-based regimen with improved toxicity profile in adjuvant setting for patients with HER2-positive disease
-
Slamon D, et al. Adjuvant trastuzumab in HER2-positive breast cancer. N Engl J Med. 2011;365 (14):1273-83. Results from this randomized trial indicate that trastuzumab plus non-Anthracycline chemotherapy is reasonable and effective alternative to anthracycline-based regimen with improved toxicity profile in adjuvant setting for patients with HER2-positive disease.
-
(2011)
N Engl J Med.
, vol.365
, Issue.14
, pp. 1273-1283
-
-
Slamon, D.1
-
20
-
-
73349115249
-
Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzumab, as adjuvant treatments of breast cancer: Final results of the FinHer Trial
-
All of the previously described trials used adjuvant trastuzumab for at least one year. The FinHER trial tested shorter course of trastuzumab. Even with short course of trastuzumab patients tended to have better DFS than those treated with chemotherapy only
-
Joensuu H, et al. Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzumab, as adjuvant treatments of breast cancer: Final results of the FinHer Trial. J Clin Oncol. 2009;27(34):5685-92. All of the previously described trials used adjuvant trastuzumab for at least one year. The FinHER trial tested shorter course of trastuzumab. Even with short course of trastuzumab patients tended to have better DFS than those treated with chemotherapy only.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.34
, pp. 5685-5692
-
-
Joensuu, H.1
-
21
-
-
83355163400
-
Sequential versus concurrent trastuzumab in adjuvant chemotherapy for breast cancer
-
Perez EA, et al. Sequential versus concurrent trastuzumab in adjuvant chemotherapy for breast cancer. J Clin Oncol. 2011;29(34):4491-7.
-
(2011)
J Clin Oncol.
, vol.29
, Issue.34
, pp. 4491-4497
-
-
Perez, E.A.1
-
22
-
-
74949141693
-
Trastuzumab for patients with axillary-node-positive breast cancer: Results of the FNCLCC-PACS 04 trial
-
Spielmann M, et al. Trastuzumab for patients with axillary-node-positive breast cancer: Results of the FNCLCC-PACS 04 trial. J Clin Oncol. 2009;27 (36):6129-34.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.36
, pp. 6129-6134
-
-
Spielmann, M.1
-
23
-
-
41649098657
-
The safety of dose-dense doxorubicin and cyclophosphamide followed by paclitaxel with trastuzumab in HER-2/neu overexpressed/amplified breast cancer
-
Dang C, et al. The safety of dose-dense doxorubicin and cyclophosphamide followed by paclitaxel with trastuzumab in HER-2/neu overexpressed/amplified breast cancer. J Clin Oncol. 2008;26(8):1216-22.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.8
, pp. 1216-1222
-
-
Dang, C.1
-
24
-
-
73349119689
-
High risk of recurrence for patients with breast cancer who have human epidermal growth factor receptor 2-positive, nodenegative tumors 1 cm or smaller
-
Gonzalez-Angulo AM, et al. High risk of recurrence for patients with breast cancer who have human epidermal growth factor receptor 2-positive, nodenegative tumors 1 cm or smaller. J Clin Oncol. 2009;27(34):5700-6.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.34
, pp. 5700-5706
-
-
Gonzalez-Angulo, A.M.1
-
25
-
-
73349142700
-
Clinical relevance of HER2 overexpression/amplification in patients with small tumor size and node-negative breast cancer
-
Curigliano G, et al. Clinical relevance of HER2 overexpression/ amplification in patients with small tumor size and node-negative breast cancer. J Clin Oncol. 2009;27(34):5693-9.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.34
, pp. 5693-5699
-
-
Curigliano, G.1
-
26
-
-
33748648138
-
Heart of darkness: The downside of trastuzumab
-
Hayes DF, Picard MH. Heart of darkness: The downside of trastuzumab. J Clin Oncol. 2006;24 (25):4056-8.
-
(2006)
J Clin Oncol.
, vol.24
, Issue.25
, pp. 4056-4058
-
-
Hayes, D.F.1
Picard, M.H.2
-
27
-
-
41649083764
-
Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the North Central Cancer Treatment Group N9831 adjuvant breast cancer trial
-
Perez EA, et al. Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the North Central Cancer Treatment Group N9831 adjuvant breast cancer trial. J Clin Oncol. 2008;26(8):1231-8.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.8
, pp. 1231-1238
-
-
Perez, E.A.1
-
28
-
-
77955284952
-
Independent adjudication of symptomatic heart failure with the use of doxorubicin and cyclophosphamide followed by trastuzumab adjuvant therapy: A combined review of cardiac data from the National Surgical Adjuvant breast and Bowel Project B-31 and the North Central Cancer Treatment Group N9831 clinical trials
-
Russell SD, et al. Independent adjudication of symptomatic heart failure with the use of doxorubicin and cyclophosphamide followed by trastuzumab adjuvant therapy: A combined review of cardiac data from the National Surgical Adjuvant breast and Bowel Project B-31 and the North Central Cancer Treatment Group N9831 clinical trials. J Clin Oncol. 2010;28(21):3416-21.
-
(2010)
J Clin Oncol.
, vol.28
, Issue.21
, pp. 3416-3421
-
-
Russell, S.D.1
-
30
-
-
84857099997
-
Results of a randomized, double-blind, multicenter, placebo controlled study of adjuvant lapatinib in women with early-stage Erb2-overexpressing braeast cancer
-
Goss P, et al. Results of a randomized, double-blind, multicenter, placebo controlled study of adjuvant lapatinib in women with early-stage Erb2-overexpressing braeast cancer. San Antonio Breast Cancer Symposium., 2011.
-
(2011)
San Antonio Breast Cancer Symposium
-
-
Goss, P.1
-
31
-
-
20544460650
-
Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: Results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer
-
Buzdar AU, et al. Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: Results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer. J Clin Oncol. 2005;23(16):3676-85.
-
(2005)
J Clin Oncol.
, vol.23
, Issue.16
, pp. 3676-3685
-
-
Buzdar, A.U.1
-
32
-
-
80051508992
-
TBCRC 006: A multicenter phase II of neoadjuvant lapatinib and trastuzumab in patients with HER2-overexpressing breast cancer
-
p. Abstract #505
-
Chang J, et al. TBCRC 006: A multicenter phase II of neoadjuvant lapatinib and trastuzumab in patients with HER2-overexpressing breast cancer. J Clin Oncol; suppl, 2011. 29: P. Abstract #505.
-
(2011)
J Clin Oncol; suppl
, pp. 29
-
-
Chang, J.1
-
33
-
-
79953772036
-
Lapatinib versus trastuzumab in combination with neoadjuvant antracycline-Taxane-based chemotherapy: Primary efficacy endpoint analysis of the geparquinto study (GBG 44)
-
Untch M, Lapatinib versus Trastuzumab in Combination with Neoadjuvant Antracycline-Taxane-Based Chemotherapy: Primary Efficacy Endpoint Analysis of the GEPARQUINTO STUDY (GBG 44). Cancer Research Supp, 2010. 70: P. 81s.
-
(2010)
Cancer Research Supp
, vol.70
-
-
Untch, M.1
-
34
-
-
79952274439
-
Neoadjuvant Pertuzumab (P) and Trastuzumab (H): Antitumor and Safety Analysis of a Randomized Phase II NeoSphere
-
Gianni L, et al. Neoadjuvant Pertuzumab (P) and Trastuzumab (H): Antitumor and Safety Analysis of a Randomized Phase II (NeoSphere). Cancer Research Supp, 2010. 70: P. 82s.
-
(2010)
Cancer Research Supp
, vol.70
-
-
Gianni, L.1
-
35
-
-
79952258750
-
First results of the NeoALTTO Trial (BIG 01-06/EGF 106903): A Phase III, randomized, Open Label, Neoadjuvant Study of Lapatinib, Trastuzumab, and Their Combination Plus Paclitaxel in women with HER2-Positive Primary Breast Cancer
-
Baselga, J.et al. First results of the NeoALTTO Trial (BIG 01-06/EGF 106903): A Phase III, randomized, Open Label, Neoadjuvant Study of Lapatinib, Trastuzumab, and Their Combination Plus Paclitaxel in women with HER2-Positive Primary Breast Cancer. Cancer Research Supp, 2010. 70: P. 82s
-
(2010)
Cancer Research Supp
, vol.70
-
-
Baselga, J.1
-
36
-
-
33644600485
-
Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, pertuzumab
-
Adams CW, et al. Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, pertuzumab. Cancer Immunol Immunother. 2006;55(6):717-27.
-
(2006)
Cancer Immunol Immunother.
, vol.55
, Issue.6
, pp. 717-727
-
-
Adams, C.W.1
-
37
-
-
84862914692
-
Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
-
Baselga J, et al. Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med. 2012;366(2):109-19.
-
(2012)
N Engl J Med.
, vol.366
, Issue.2
, pp. 109-119
-
-
Baselga, J.1
-
38
-
-
56449129810
-
Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibodycytotoxic drug conjugate
-
Lewis Phillips GD, et al. Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibodycytotoxic drug conjugate. Cancer Res. 2008;68 (22):9280-90.
-
(2008)
Cancer Res.
, vol.68
, Issue.22
, pp. 9280-9290
-
-
Lewis Phillips, G.D.1
-
39
-
-
79952092706
-
Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy
-
Burris 3rd HA, et al. Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy. J Clin Oncol. 2011;29 (4):398-405.
-
(2011)
J Clin Oncol.
, vol.29
, Issue.4
, pp. 398-405
-
-
Burris III, H.A.1
-
40
-
-
79955843985
-
Efficacy and Safety of Trastuzumab-DM1 Versus Trastuzumab plus Docetaxel in HER2-Positive Metastatic Breast Cancer Patients with No Prior Chemotherapy for Metastatic Disease: Preliminary results of a Randomized, Multicenter, Open-Label Phase 2 Study
-
Perez E, et al. Efficacy and Safety of Trastuzumab-DM1 Versus Trastuzumab plus Docetaxel in HER2-Positive Metastatic Breast Cancer Patients with No Prior Chemotherapy for Metastatic Disease: Preliminary results of a Randomized, Multicenter, Open-Label Phase 2 Study. 35th Congress of the European Society of Medical Oncology, 2010.
-
(2010)
35th Congress of the European Society of Medical Oncology
-
-
Perez, E.1
|