Reaction of β-blockers and β-agonist pharmaceuticals with aqueous chlorine. Investigation of kinetics and by-products by liquid chromatography quadrupole time-of-flight mass spectrometry

Analytical and Bioanalytical Chemistry

Volumn 403, Issue 8, 2012, Pages 2385-2395

  Quintana, José Benito ^a   Rodil, Rosario ^a   Cela, Rafael ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

By products; Chlorination; Liquid chromatography mass spectrometry (LC MS); Pharmaceuticals; Time of flight (TOF)

Indexed keywords

ATENOLOL; BOX-BEHNKEN; CHLORINE DOSAGE; CHLORINE DOSE; DEGRADATION KINETICS; HALF LIVES; HIGH RESOLUTION; LC-Q-TOF MS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; OPERATIONAL PARAMETERS; QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY; QUADRUPOLES; SALBUTAMOL; SAMPLE PH; TIME COURSE; TIME OF FLIGHT; TIME-OF-FLIGHT SYSTEM; TRANSFORMATION PATHWAYS; WATER CHLORINATION; WATER SAMPLES;

BROMINE COMPOUNDS; BYPRODUCTS; CHLORINATION; DEGRADATION; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

CHLORINE;

ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CHLORINE; PROPRANOLOL; SALBUTAMOL; WATER;

ARTICLE; CHEMISTRY; HALOGENATION; ISOLATION AND PURIFICATION; KINETICS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; WATER MANAGEMENT; WATER POLLUTANT;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ALBUTEROL; ATENOLOL; CHLORINE; CHROMATOGRAPHY, LIQUID; HALOGENATION; KINETICS; MASS SPECTROMETRY; PROPRANOLOL; WATER; WATER POLLUTANTS, CHEMICAL; WATER PURIFICATION;

EID: 84863719121     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-011-5707-7     Document Type: Article

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