Annexin A1 and A2: Roles in retrograde trafficking of Shiga toxin

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Tcatchoff, Lionel ^a   Andersson, Sofia ^a   Utskarpen, Audrun ^a,b   Klokk, Tove Irene ^a   Skånland, Sigrid S ^a,b   Pust, Sascha ^a   Gerke, Volker ^c   Sandvig, Kirsten ^a,b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; LIPOCORTIN 1; LIPOCORTIN 2; PHOSPHOLIPASE A2; PROTEIN KINASE C DELTA; RICIN; SHIGA TOXIN;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOPLASM; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GOLGI COMPLEX; HUMAN; HUMAN CELL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; TOXIN ANALYSIS;

ACETOPHENONES; ANNEXIN A1; ANNEXIN A2; BENZOPYRANS; ENDOCYTOSIS; ENDOSOMES; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; IMIDAZOLES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASES A2; PROTEIN BINDING; PROTEIN KINASE C-DELTA; PROTEIN TRANSPORT; PYRIDINES; RECEPTOR, IGF TYPE 2; RICIN; RNA, SMALL INTERFERING; SHIGA TOXIN; TRANS-GOLGI NETWORK;

BACTERIA (MICROORGANISMS);

EID: 84863710208     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040429     Document Type: Article

References (72)

1. Engedal N, Skotland T, Torgersen ML, Sandvig K, (2010) Shiga toxin and its use in targeted cancer therapy and imaging. Microb Biotechnol 4: 32-46.
2. Sandvig K, Torgersen ML, Engedal N, Skotland T, Iversen TG, (2010) Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine. FEBS Lett 584: 2626-2634.
3. Sandvig K, van Deurs B, (2005) Delivery into cells: lessons learned from plant and bacterial toxins. Gene Ther 12: 865-872.
4. Lauvrak SU, Torgersen ML, Sandvig K, (2004) Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin. J Cell Sci 117: 2321-2331.
5. Popoff V, Mardones GA, Tenza D, Rojas R, Lamaze C, et al. (2007) The retromer complex and clathrin define an early endosomal retrograde exit site. J Cell Sci 120: 2022-2031.
6. Popoff V, Mardones GA, Bai SK, Chambon V, Tenza D, et al. (2009) Analysis of articulation between clathrin and retromer in retrograde sorting on early endosomes. Traffic 10: 1868-1880.
7. Skanland SS, Walchli S, Sandvig K, (2009) beta-arrestins attenuate p38 mediated endosome to Golgi transport. Cell Microbiol 11: 796-807.
8. Bujny MV, Popoff V, Johannes L, Cullen PJ, (2007) The retromer component sorting nexin-1 is required for efficient retrograde transport of Shiga toxin from early endosome to the trans Golgi network. J Cell Sci 120: 2010-2021.
9. Dyve AB, Bergan J, Utskarpen A, Sandvig K, (2009) Sorting nexin 8 regulates endosome-to-Golgi transport. Biochem Biophys Res Commun 390: 109-114.
10. Skanland SS, Walchli S, Utskarpen A, Wandinger-Ness A, Sandvig K, (2007) Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins. Traffic 8: 297-309.
11. Utskarpen A, Slagsvold HH, Dyve AB, Skanland SS, Sandvig K, (2007) SNX1 and SNX2 mediate retrograde transport of Shiga toxin. Biochem Biophys Res Commun 358: 566-570.
12. Raa H, Grimmer S, Schwudke D, Bergan J, Walchli S, et al. (2009) Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin. Traffic 10: 868-882.
13. Windschiegl B, Orth A, Romer W, Berland L, Stechmann B, et al. (2009) Lipid reorganization induced by Shiga toxin clustering on planar membranes. PLoS ONE 4: e6238.
14. Skanland SS, Walchli S, Brech A, Sandvig K, (2009) SNX4 in complex with clathrin and dynein: implications for endosome movement. PLoS ONE 4: e5935.
15. Torgersen ML, Walchli S, Grimmer S, Skanland SS, Sandvig K, (2007) Protein kinase Cdelta is activated by Shiga toxin and regulates its transport. J Biol Chem 282: 16317-16328.
16. Walchli S, Skanland SS, Gregers TF, Lauvrak SU, Torgersen ML, et al. (2008) The Mitogen-activated protein kinase p38 links Shiga Toxin-dependent signaling and trafficking. Mol Biol Cell 19: 95-104.
17. Gerke V, Creutz CE, Moss SE, (2005) Annexins: linking Ca2+ signalling to membrane dynamics. Nat Rev Mol Cell Biol 6: 449-461.
18. Gerke V, Moss SE, (2002) Annexins: from structure to function. Physiol Rev 82: 331-371.
19. Futter CE, White IJ, (2007) Annexins and endocytosis. Traffic 8: 951-958.
20. Grewal T, Enrich C, (2009) Annexins-modulators of EGF receptor signalling and trafficking. Cell Signal 21: 847-858.
21. Futter CE, Felder S, Schlessinger J, Ullrich A, Hopkins CR, (1993) Annexin I is phosphorylated in the multivesicular body during the processing of the epidermal growth factor receptor. J Cell Biol 120: 77-83.
22. White IJ, Bailey LM, Aghakhani MR, Moss SE, Futter CE, (2006) EGF stimulates annexin 1-dependent inward vesiculation in a multivesicular endosome subpopulation. EMBO J 25: 1-12.
23. Emans N, Gorvel JP, Walter C, Gerke V, Kellner R, et al. (1993) Annexin II is a major component of fusogenic endosomal vesicles. J Cell Biol 120: 1357-1369.
24. Harder T, Gerke V, (1993) The subcellular distribution of early endosomes is affected by the annexin II2p11(2) complex. J Cell Biol 123: 1119-1132.
25. Morel E, Gruenberg J, (2009) Annexin A2 binding to endosomes and functions in endosomal transport are regulated by tyrosine 23 phosphorylation. J Biol Chem 284: 1604-1611.
26. Turpin E, Russo-Marie F, Dubois T, de PC, Alfsen A, Bomsel M, (1998) In adrenocortical tissue, annexins II and VI are attached to clathrin coated vesicles in a calcium-independent manner. Biochim Biophys Acta 1402: 115-130.
27. Zobiack N, Rescher U, Ludwig C, Zeuschner D, Gerke V, (2003) The annexin 2/S100A10 complex controls the distribution of transferrin receptor-containing recycling endosomes. Mol Biol Cell 14: 4896-4908.
28. Mayran N, Parton RG, Gruenberg J, (2003) Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells. EMBO J 22: 3242-3253.
29. Leslie CC, Gangelhoff TA, Gelb MH, (2010) Localization and function of cytosolic phospholipase A2alpha at the Golgi. Biochimie 92: 620-626.
30. de Figueiredo P, Doody A, Polizotto RS, Drecktrah D, Wood S, et al. (2001) Inhibition of transferrin recycling and endosome tubulation by phospholipase A2 antagonists. J Biol Chem 276: 47361-47370.
31. Doody AM, Antosh AL, Brown WJ, (2009) Cytoplasmic phospholipase A2 antagonists inhibit multiple endocytic membrane trafficking pathways. Biochem Biophys Res Commun 388: 695-699.
32. Kim S, Ko J, Kim JH, Choi EC, Na DS, (2001) Differential effects of annexins I, II, III, and V on cytosolic phospholipase A2 activity: specific interaction model. FEBS Lett 489: 243-248.
33. Wu T, Angus CW, Yao XL, Logun C, Shelhamer JH, (1997) P11, a unique member of the S100 family of calcium-binding proteins, interacts with and inhibits the activity of the 85-kDa cytosolic phospholipase A2. J Biol Chem 272: 17145-17153.
34. Tian W, Wijewickrama GT, Kim JH, Das S, Tun MP, et al. (2008) Mechanism of regulation of group IVA phospholipase A2 activity by Ser727 phosphorylation. J Biol Chem 283: 3960-3971.
35. Herbert SP, Odell AF, Ponnambalam S, Walker JH, (2007) The confluence-dependent interaction of cytosolic phospholipase A2-alpha with annexin A1 regulates endothelial cell prostaglandin E2 generation. J Biol Chem 282: 34468-34478.
36. Goettsch S, Badea RA, Mueller JW, Wotzlaw C, Schoelermann B, et al. (2006) Human TPST1 transmembrane domain triggers enzyme dimerisation and localisation to the Golgi compartment. J Mol Biol 361: 436-449.
37. Lee RW, Huttner WB, (1983) Tyrosine-O-sulfated proteins of PC12 pheochromocytoma cells and their sulfation by a tyrosylprotein sulfotransferase. J Biol Chem 258: 11326-11334.
38. Johannes L, Tenza D, Antony C, Goud B, (1997) Retrograde transport of KDEL-bearing B-fragment of Shiga toxin. J Biol Chem 272: 19554-19561.
39. Rapak A, Falnes PO, Olsnes S, (1997) Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol. Proc Natl Acad Sci U S A 94: 3783-3788.
40. Barbero P, Bittova L, Pfeffer SR, (2002) Visualization of Rab9-mediated vesicle transport from endosomes to the trans-Golgi in living cells. J Cell Biol 156: 511-518.
41. Griffiths G, Hoflack B, Simons K, Mellman I, Kornfeld S, (1988) The mannose 6-phosphate receptor and the biogenesis of lysosomes. Cell 52: 329-341.
42. Spooner RA, Watson P, Smith DC, Boal F, Amessou M, et al. (2008) The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochem J 414: 471-484.
43. Sakaguchi M, Murata H, Sonegawa H, Sakaguchi Y, Futami J, et al. (2007) Truncation of annexin A1 is a regulatory lever for linking epidermal growth factor signaling with cytosolic phospholipase A2 in normal and malignant squamous epithelial cells. J Biol Chem 282: 35679-35686.
44. Moes M, Boonstra J, Regan-Klapisz E, (2010) Novel role of cPLA(2)alpha in membrane and actin dynamics. Cell Mol Life Sci 67: 1547-1557.
45. San Pietro E, Capestrano M, Polishchuk EV, DiPentima A, Trucco A, et al. (2009) Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport. PLoS Biol 7: e1000194.
46. Evans JH, Spencer DM, Zweifach A, Leslie CC, (2001) Intracellular calcium signals regulating cytosolic phospholipase A2 translocation to internal membranes. J Biol Chem 276: 30150-30160.
47. Murakami M, Kudo I, (2001) Diversity and regulatory functions of mammalian secretory phospholipase A2s. Adv Immunol 77: 163-194.
48. Yang JS, Valente C, Polishchuk RS, Turacchio G, Layre E, et al. (2011) COPI acts in both vesicular and tubular transport. Nat Cell Biol 13: 996-1003.
49. Soderberg O, Gullberg M, Jarvius M, Ridderstrale K, Leuchowius KJ, et al. (2006) Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nat Methods 3: 995-1000.
50. Klinger SC, Glerup S, Raarup MK, Mari MC, Nyegaard M, et al. (2011) SorLA regulates the activity of lipoprotein lipase by intracellular trafficking. J Cell Sci 124: 1095-1105.
51. Cai B, Caplan S, Naslavsky N, (2012) cPLA2alpha and EHD1 interact and regulate the vesiculation of cholesterol-rich, GPI-anchored, protein-containing endosomes. Mol Biol Cell 23: 1874-1888.
52. Utskarpen A, Slagsvold HH, Iversen TG, Walchli S, Sandvig K, (2006) Transport of ricin from endosomes to the Golgi apparatus is regulated by Rab6A and Rab6A'. Traffic 7: 663-672.
53. Johannes L, Popoff V, (2008) Tracing the retrograde route in protein trafficking. Cell 135: 1175-1187.
54. Johannes L, Romer W, (2010) Shiga toxins-from cell biology to biomedical applications. Nat Rev Microbiol 8: 105-116.
55. Romer W, Berland L, Chambon V, Gaus K, Windschiegl B, et al. (2007) Shiga toxin induces tubular membrane invaginations for its uptake into cells. Nature 450: 670-675.
56. Creutz CE, Snyder SL, (2005) Interactions of annexins with the mu subunits of the clathrin assembly proteins. Biochemistry 44: 13795-13806.
57. Rojas R, Kametaka S, Haft CR, Bonifacino JS, (2007) Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. Mol Cell Biol 27: 1112-1124.
58. Arighi CN, Hartnell LM, Aguilar RC, Haft CR, Bonifacino JS, (2004) Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor. J Cell Biol 165: 123-133.
59. Seaman MN, (2004) Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer. J Cell Biol 165: 111-122.
60. Wilcke M, Johannes L, Galli T, Mayau V, Goud B, et al. (2000) Rab11 regulates the compartmentalization of early endosomes required for efficient transport from early endosomes to the trans-golgi network. J Cell Biol 151: 1207-1220.
61. Du X, Kumar J, Ferguson C, Schulz TA, Ong YS, et al. (2011) A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking. J Cell Biol 192: 121-135.
62. Pfeffer SR, (2009) Multiple routes of protein transport from endosomes to the trans Golgi network. FEBS Lett 583: 3811-3816.
63. Llado A, Tebar F, Calvo M, Moreto J, Sorkin A, et al. (2004) Protein kinaseCdelta-calmodulin crosstalk regulates epidermal growth factor receptor exit from early endosomes. Mol Biol Cell 15: 4877-4891.
64. Llado A, Timpson P, Vila de MS, Moreto J, Pol A, et al. (2008) Protein kinase Cdelta and calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2/3 complex and cortactin. Mol Biol Cell 19: 17-29.
65. Croxtall JD, Gilroy DW, Solito E, Choudhury Q, Ward BJ, et al. (2003) Attenuation of glucocorticoid functions in an Anx-A1-/- cell line. Biochem J 371: 927-935.
66. Hannon R, Croxtall JD, Getting SJ, Roviezzo F, Yona S, et al. (2003) Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse. FASEB J 17: 253-255.
67. Cubells L, de Muga SV, Tebar F, Bonventre JV, Balsinde J, et al. (2008) Annexin A6-induced inhibition of cytoplasmic phospholipase A2 is linked to caveolin-1 export from the Golgi. J Biol Chem 283: 10174-10183.
68. Reverter M, Rentero C, de Muga SV, varez-Guaita A, Mulay V, et al. (2011) Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function. Mol Biol Cell 22: 4108-4123.
69. Thiel C, Osborn M, Gerke V, (1992) The tight association of the tyrosine kinase substrate annexin II with the submembranous cytoskeleton depends on intact p11- and Ca(2+)-binding sites. J Cell Sci 103 (Pt 3): 733-742.
70. Lauvrak SU, Walchli S, Iversen TG, Slagsvold HH, Torgersen ML, et al. (2006) Shiga toxin regulates its entry in a Syk-dependent manner. Mol Biol Cell 17: 1096-1109.
71. Zobiack N, Gerke V, Rescher U, (2001) Complex formation and submembranous localization of annexin 2 and S100A10 in live HepG2 cells. FEBS Lett 500: 137-140.
72. Fredriksson S, Gullberg M, Jarvius J, Olsson C, Pietras K, et al. (2002) Protein detection using proximity-dependent DNA ligation assays. Nat Biotechnol 20: 473-477.