Double-masked randomized clinical trial evaluating the effect of a triclosan/copolymer dentifrice on periodontal healing after one-stage full-mouth debridement

Journal of Periodontology

Volumn 83, Issue 7, 2012, Pages 909-916

  Pera, Claudia ^a   Ueda, Paulo ^a   Casarin, Renato Corrêa Viana ^a   Ribeiro, Fernanda Vieira ^a   Pimentel, Suzana Peres ^a   Casati, Márcio Zaffalon ^a   Cirano, Fabiano Ribeiro ^a  

^a PAULISTA UNIVERSITY   (Brazil)

Author keywords

Antimicrobial agents; Chronic periodontitis; Dental scaling; Dentifrices; Randomized clinical trial; Triclosan

Indexed keywords

ANTICARIES AGENT; FLUORIDE SODIUM; PLACEBO; POLYMER; TOOTHPASTE; TOPICAL ANTIINFECTIVE AGENT; TRICLOSAN;

ADULT; ARTICLE; CHRONIC PERIODONTITIS; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; FOLLOW UP; GINGIVA BLEEDING; GINGIVA DISEASE; HUMAN; INSTRUMENTATION; MALE; METHODOLOGY; MIDDLE AGED; PERIODONTAL DISEASE; PERIODONTAL POCKET; PERIODONTICS; PREVENTIVE DENTISTRY; RANDOMIZED CONTROLLED TRIAL; TOOTH PLAQUE; ULTRASOUND THERAPY;

ADULT; ANTI-INFECTIVE AGENTS, LOCAL; CARIOSTATIC AGENTS; CHRONIC PERIODONTITIS; DENTAL PLAQUE; DENTAL PLAQUE INDEX; DENTIFRICES; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; GINGIVAL HEMORRHAGE; GINGIVAL RECESSION; HUMANS; MALE; MIDDLE AGED; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL DEBRIDEMENT; PERIODONTAL INDEX; PERIODONTAL POCKET; PLACEBOS; POLYMERS; SODIUM FLUORIDE; TRICLOSAN; ULTRASONIC THERAPY;

EID: 84863689059     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2011.110348     Document Type: Article

References (39)

1. Badersten A, Nilveus R, Egelberg J. Effect of nonsurgical periodontal therapy. II. Severely advanced periodontitis. J Clin Periodontol 1984;11:63-76.
2. Morris AJ, Steele J, White DA. The oral cleanliness and periodontal health of UK adults in 1998. Br Dent J 2001;191:186-192. (Pubitemid 33755285)
3. Davies RM. The clinical efficacy of triclosan/copolymer and other common therapeutic approaches to periodontal health. Clin Microbiol Infect 2007;13(Suppl. 4): 25-29. (Pubitemid 47308188)
4. Jones CL, Saxton CA, Ritchie JA. Microbiological and clinical effects of a dentifrice containing zinc citrate and Triclosan in the human experimental gingivitis model. J Clin Periodontol 1990;17:570-574. (Pubitemid 20293573)
5. Paraskevas S. Randomized controlled clinical trials on agents used for chemical plaque control. Int J Dent Hyg 2005;3:162-178.
6. Modéer T, Bengtsson A, Rölla G. Triclosan reduces prostaglandin biosynthesis in human gingival fibroblasts challenged with interleukin-1 in vitro. J Clin Periodontol 1996;23:927-933.
7. Arancibia R, Cáceres M, Martínez J, Smith PC. Triclosan inhibits tumor necrosis factor-alpha-stimulated urokinase production in human gingival fibroblasts. J Periodontal Res 2009;44:726-735.
8. Barnes VM, Richter R, Vandeven M, Xu T, DeVizio W. Clinical investigation of the antiplaque efficacy of a new variant of a commercially available triclosan/copolymer/fluoride dentifrice. J Clin Dent 2008;19:81-84.
9. Barros SP, Wirojchanasak S, Barrow DA, Panagakos FS, Devizio W, Offenbacher S. Triclosan inhibition of acute and chronic inflammatory gene pathways. J Clin Periodontol 2010;37:412-418.
10. Villalpando KT, Casarin RC, Pimentel SP, Cirano FR, Casati MZ. A randomized clinical evaluation of triclosan-containing dentifrice and mouthwash association in the control of plaque and gingivitis. Quintessence Int 2010;41:855-861.
11. Davies RM, Ellwood RP, Davies GM. The effectiveness of a toothpaste containing triclosan and polyvinylmethyl ether maleic acid copolymer in improving plaque control and gingival health: A systematic review. J Clin Periodontol 2004;31:1029-1033. (Pubitemid 39643698)
12. Stephen KW, Saxton CA, Jones CL, Ritchie JA, Morrison T. Control of gingivitis and calculus by a dentifrice containing a zinc salt and triclosan. J Periodontol 1990;61:674-679. (Pubitemid 20382649)
13. Lindhe J, Rosling B, Socransky SS, Volpe AR. The effect of a triclosan-containing dentifrice on established plaque and gingivitis. J Clin Periodontol 1993; 20:327-334. (Pubitemid 23274600)
14. Ramberg P, Furuichi Y, Sherl D, et al. The effect of triclosan on developing gingivitis. J Clin Periodontol 1995;22:442-448.
15. Ciancio S, Panagakos FS. Superior management of plaque and gingivitis through the use of a triclosan/copolymer dentifrice. J Clin Dent 2010;21:93-95.
16. Rosling B, Wannfors B, Volpe AR, Furuichi Y, Ramberg P, Lindhe J. The use of a triclosan/copolymer dentifrice may retard the progression of periodontitis. J Clin Periodontol 1997;24:873-880. (Pubitemid 127731634)
17. Cullinan MP, Westerman B, Hamlet SM, Palmer JE, Faddy MJ, Seymour GJ. The effect of a triclosancontaining dentifrice on the progression of periodontal disease in an adult population. J Clin Periodontol 2003;30:414-419. (Pubitemid 38037099)
18. Kerdvongbundit V, Wikesjö UM. Effect of triclosan on healing following non-surgical periodontal therapy in smokers. J Clin Periodontol 2003;30:1024-1030. (Pubitemid 38011205)
19. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999;4:1-6.
20. Zanatta GM, Bittencourt S, Nociti FH Jr., Sallum EA, Sallum AW, Casati MZ. Periodontal debridement with povidone-iodine in periodontal treatment: Short-term clinical and biochemical observations. J Periodontol 2006;77:498-505. (Pubitemid 44740674)
21. Del Peloso Ribeiro E, Bittencourt S, Sallum EA, Nociti FH Jr., Goncxalves RB, Casati MZ. Periodontal debridement as a therapeutic approach for severe chronic periodontitis: A clinical, microbiological and immunological study. J Clin Periodontol 2008;35: 789-798.
22. Ribeiro Edel P, Bittencourt S, Zanin IC, et al. Fullmouth ultrasonic debridement associated with amoxicillin and metronidazole in the treatment of severe chronic periodontitis. J Periodontol 2009;80:1254-1264.
23. Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J 1975;25: 229-235.
24. Mühlemann HR, Son S. Gingival sulcus bleeding - A leading symptom in initial gingivitis. Helv Odontol Acta 1971;15:107-113.
25. Ower P. The role of self-administered plaque control in the management of periodontal diseases. I. A review of the evidence. Dent Update 2003;30:60-64, 66, 68.
26. Denepitiya JL, Fine D, Singh S, DeVizio W, Volpe AR, Person P. Effect upon plaque formation and gingivitis of a triclosan/copolymer/fluoride dentifrice: A 6-month clinical study. Am J Dent 1992;5:307-311.
27. Gaffar A, Afflitto J, Nabi N, Herles S, Kruger I, Olsen S. Recent advances in plaque, gingivitis, tartar and caries prevention technology. Int Dent J 1994; 44(Suppl. 1): 63-70.
28. Jenkins S, Addy M, Newcombe R. Triclosan and sodium lauryl sulphate mouthwashes. Effects on salivary bacterial counts. J Clin Periodontol 1991;17:85-89. (Pubitemid 20078162)
29. Hawley GM, Hamilton FA, Worthington HV, et al. A 30-month study investigating the effect of adding triclosan/copolymer to a fluoride dentifrice. Caries Res 1995;29:163-167.
30. Cullinan MP, Hamlet SM, Westerman B, Palmer JE, Faddy MJ, Seymour GJ. Acquisition and loss of Porphyromonas gingivalis, Actinobacillus ctinomycetemcomitans and Prevotella intermedia over a 5-year period: Effect of a triclosan/copolymer dentifrice. J Clin Periodontol 2003;30:532-541. (Pubitemid 38011183)
31. Kinane DF. Regulators of tissue destruction and homeostasis as diagnostic aids in periodontology. Periodontol 2000 2000;24:215-225.
32. Haffajee AD, Torresyap G, Socransky SS. Clinical changes following four different periodontal therapies for the treatment of chronic periodontitis: 1-year results. J Clin Periodontol 2007;34:243-253.
33. Quirynen M, Mongardini C, de Soete M, et al. The role of chlorhexidine in the one-stage full-mouth disinfection treatment of patients with advanced adult periodontitis. Long-term clinical and microbiological observations. J Clin Periodontol 2000;27:578-589.
34. Quirynen M, Teughels W, van Steenberghe D. Impact of antiseptics on one-stage, full-mouth disinfection. J Clin Periodontol 2006;33:49-52. (Pubitemid 43423571)
35. Cortelli SC, Cortelli JR, Holzhausen M, et al. Essential oils in one-stage full-mouth disinfection: Double-blind, randomized clinical trial of long-term clinical, microbial and salivary effects. J Clin Periodontol 2009;36: 333-342.
36. Flötra L. Different modes of chlorhexidine application and related local side effects. J Periodontal Res Suppl 1973;12:41-44.
37. Löe H, Schiött CR. The effect of mouthrinses and topical application of chlorhexidine on the development of dental plaque and gingivitis inman. J Periodontal Res 1970;5:79-83.
38. Koshy G, Kawashima Y, Kiji M, et al. Effects of singlevisit full-mouth ultrasonic debridement versus quadrant-wise ultrasonic debridement. J Clin Periodontol 2005;32:734-743. (Pubitemid 40923048)
39. Wennström JL, Tomasi C, Bertelle A, Dellasega E. Full-mouth ultrasonic debridement versus quadrant scaling and root planing as an initial approach in the treatment of chronic periodontitis. J Clin Periodontol 2005;32:851-859. (Pubitemid 41008322)