Standardised optical multichannel (optimul) platelet aggregometry using high-speed shaking and fixed time point readings

Platelets

Volumn 23, Issue 5, 2012, Pages 404-408

  Chan, Melissa V ^a   Warner, Timothy D ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Aggregation; platelet testing; thrombosis

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ADENOSINE DIPHOSPHATE; ADRENALIN; ARACHIDONIC ACID; COLLAGEN; RISTOCETIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE 6;

BLOOD VOLUME; COST EFFECTIVENESS ANALYSIS; ERGOMETRY; GOLD STANDARD; HUMAN; LETTER; LIGHT TRANSMISSION AGGREGOMETRY; MULTICHANNEL RECORDER; PRIORITY JOURNAL; ROOM TEMPERATURE; THROMBOCYTE; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION;

HUMANS; PLATELET AGGREGATION; PLATELET FUNCTION TESTS; PREDICTIVE VALUE OF TESTS;

EID: 84863683268     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.3109/09537104.2011.603066     Document Type: Letter

References (7)

1. Chan MV, Armstrong PC, Papalia F, Kirkby NS, Warner TD. Optical multichannel (optimul) platelet aggregometry in 96- well plates as an additional method of platelet reactivity testing. Platelets 2011, in press.
2. Michelson AD. Platelet function testing in cardiovascular diseases. Circulation 2004;110:e489-493.
3. Bednar B, Condra C, Gould RJ, Connolly TM. Platelet aggregation monitored in a 96 well microplate reader is useful for evaluation of platelet agonists and antagonists. Thromb Res 1995;77:453-463.
4. Armstrong PC, Dhanji AR, Truss NJ, Zain ZN, Tucker AT, Mitchell JA, Warner TD. Utility of 96-well plate aggregometry and measurement of thrombi adhesion to determine aspirin and clopidogrel effectiveness. Thromb Haemostasis 2009;102:772-778.
5. Armstrong PC, Leadbeater PD, Chan MV, Kirkby NS, Jakubowski JA, Mitchell JA, Warner TD. In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation. J Thromb Haemostasis 2011;9:552-561.
6. Armstrong PC, Truss NJ, Ali FY, Dhanji AA, Vojnovic I, Zain ZN, Bishop-Bailey D, Paul-Clark MJ, Tucker AT, et al. Aspirin and the in vitro linear relationship between thromboxane A2-mediated platelet aggregation and platelet production of thromboxane A2. J Thromb Haemostasis: JTH 2008;6:1933-1943.
7. Armstrong PC, Dhanji AR, Tucker AT, Mitchell JA, Warner TD. Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy. J Thromb Haemostasis: JTH 2010;8:613-615.