-
1
-
-
25844523297
-
Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes
-
Simmonds P, Bukh J, Combet C, Deleage G, Enomoto N, et al. (2005) Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes. Hepatology 42: 962-973.
-
(2005)
Hepatology
, vol.42
, pp. 962-973
-
-
Simmonds, P.1
Bukh, J.2
Combet, C.3
Deleage, G.4
Enomoto, N.5
-
3
-
-
79551700091
-
Hypervariable region 1 differentially impacts viability of hepatitis C genotype 1-6 strains and impairs virus neutralization
-
Prentoe JC, Jensen TB, Meuleman P, Serre SB, Scheel TK, et al. (2011) Hypervariable region 1 differentially impacts viability of hepatitis C genotype 1-6 strains and impairs virus neutralization. J Virol 85: 2224-2234.
-
(2011)
J Virol
, vol.85
, pp. 2224-2234
-
-
Prentoe, J.C.1
Jensen, T.B.2
Meuleman, P.3
Serre, S.B.4
Scheel, T.K.5
-
4
-
-
20144383712
-
Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1
-
Meunier JC, Engle RE, Faulk K, Zhao M, Bartosch B, et al. (2005) Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1. Proc Natl Acad Sci U S A 102: 4560-4565.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 4560-4565
-
-
Meunier, J.C.1
Engle, R.E.2
Faulk, K.3
Zhao, M.4
Bartosch, B.5
-
5
-
-
38949168945
-
Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization
-
Scheel TK, Gottwein JM, Jensen TB, Prentoe JC, Hoegh AM, et al. (2008) Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization. Proc Natl Acad Sci U S A 105: 997-1002.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 997-1002
-
-
Scheel, T.K.1
Gottwein, J.M.2
Jensen, T.B.3
Prentoe, J.C.4
Hoegh, A.M.5
-
6
-
-
56749131299
-
Highly efficient JFH1-based cell-culture system for hepatitis C virus genotype 5a: failure of homologous neutralizing-antibody treatment to control infection
-
Jensen TB, Gottwein JM, Scheel TK, Hoegh AM, Eugen-Olsen J, et al. (2008) Highly efficient JFH1-based cell-culture system for hepatitis C virus genotype 5a: failure of homologous neutralizing-antibody treatment to control infection. J Infect Dis 198: 1756-1765.
-
(2008)
J Infect Dis
, vol.198
, pp. 1756-1765
-
-
Jensen, T.B.1
Gottwein, J.M.2
Scheel, T.K.3
Hoegh, A.M.4
Eugen-Olsen, J.5
-
7
-
-
61949320778
-
Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: role of CD81 and scavenger receptor class B type I and effect of antiviral drugs
-
Gottwein JM, Scheel TK, Jensen TB, Lademann JB, Prentoe JC, et al. (2009) Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: role of CD81 and scavenger receptor class B type I and effect of antiviral drugs. Hepatology 49: 364-377.
-
(2009)
Hepatology
, vol.49
, pp. 364-377
-
-
Gottwein, J.M.1
Scheel, T.K.2
Jensen, T.B.3
Lademann, J.B.4
Prentoe, J.C.5
-
8
-
-
33747797031
-
Treating viral hepatitis C: efficacy, side effects, and complications
-
Manns MP, Wedemeyer H, Cornberg M, (2006) Treating viral hepatitis C: efficacy, side effects, and complications. Gut 55: 1350-1359.
-
(2006)
Gut
, vol.55
, pp. 1350-1359
-
-
Manns, M.P.1
Wedemeyer, H.2
Cornberg, M.3
-
9
-
-
45749124737
-
Cutting the gordian knot-development and biological relevance of hepatitis C virus cell culture systems
-
Gottwein JM, Bukh J, (2008) Cutting the gordian knot-development and biological relevance of hepatitis C virus cell culture systems. Adv Virus Res 71: 51-133.
-
(2008)
Adv Virus Res
, vol.71
, pp. 51-133
-
-
Gottwein, J.M.1
Bukh, J.2
-
10
-
-
70349433673
-
Hepatitis C: recent successes and continuing challenges in the development of improved treatment modalities
-
Shimakami T, Lanford RE, Lemon SM, (2009) Hepatitis C: recent successes and continuing challenges in the development of improved treatment modalities. Curr Opin Pharmacol 9: 537-544.
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 537-544
-
-
Shimakami, T.1
Lanford, R.E.2
Lemon, S.M.3
-
11
-
-
77956116880
-
Resistance Analysis of the Hepatitis C Virus NS5A Inhibitor BMS-790052 in an In Vitro Replicon System
-
Fridell RA, Qiu D, Wang C, Valera L, Gao M, (2010) Resistance Analysis of the Hepatitis C Virus NS5A Inhibitor BMS-790052 in an In Vitro Replicon System. Antimicrob Agents Chemother 54: 3641-3650.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 3641-3650
-
-
Fridell, R.A.1
Qiu, D.2
Wang, C.3
Valera, L.4
Gao, M.5
-
12
-
-
79952296871
-
Recombinant HCV Variants with NS5A from Genotypes 1-7 Have Different Sensitivities to an NS5A Inhibitor but Not Interferon-alpha
-
Scheel TK, Gottwein JM, Mikkelsen LS, Jensen TB, Bukh J, (2011) Recombinant HCV Variants with NS5A from Genotypes 1-7 Have Different Sensitivities to an NS5A Inhibitor but Not Interferon-alpha. Gastroenterology 140: 1032-1042.
-
(2011)
Gastroenterology
, vol.140
, pp. 1032-1042
-
-
Scheel, T.K.1
Gottwein, J.M.2
Mikkelsen, L.S.3
Jensen, T.B.4
Bukh, J.5
-
13
-
-
75149151884
-
Resistance to Direct Antiviral Agents in Patients With Hepatitis C Virus Infection
-
Sarrazin C, Zeuzem S, (2010) Resistance to Direct Antiviral Agents in Patients With Hepatitis C Virus Infection. Gastroenterology 138: 447-462.
-
(2010)
Gastroenterology
, vol.138
, pp. 447-462
-
-
Sarrazin, C.1
Zeuzem, S.2
-
14
-
-
77952035218
-
Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
-
Gao M, Nettles RE, Belema M, Snyder LB, Nguyen VN, et al. (2010) Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect. Nature 765: 96-100.
-
(2010)
Nature
, vol.765
, pp. 96-100
-
-
Gao, M.1
Nettles, R.E.2
Belema, M.3
Snyder, L.B.4
Nguyen, V.N.5
-
15
-
-
0345144016
-
Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons
-
Gosert R, Egger D, Lohmann V, Bartenschlager R, Blum HE, et al. (2003) Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons. J Virol 77: 5487-5492.
-
(2003)
J Virol
, vol.77
, pp. 5487-5492
-
-
Gosert, R.1
Egger, D.2
Lohmann, V.3
Bartenschlager, R.4
Blum, H.E.5
-
16
-
-
10344221613
-
The NS5A protein of hepatitis C virus is a zinc metalloprotein
-
Tellinghuisen TL, Marcotrigiano J, Gorbalenya AE, Rice CM, (2004) The NS5A protein of hepatitis C virus is a zinc metalloprotein. J Biol Chem 279: 48576-48587.
-
(2004)
J Biol Chem
, vol.279
, pp. 48576-48587
-
-
Tellinghuisen, T.L.1
Marcotrigiano, J.2
Gorbalenya, A.E.3
Rice, C.M.4
-
17
-
-
0037040923
-
An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A
-
Brass V, Bieck E, Montserret R, Wolk B, Hellings JA, et al. (2002) An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A. J Biol Chem 277: 8130-8139.
-
(2002)
J Biol Chem
, vol.277
, pp. 8130-8139
-
-
Brass, V.1
Bieck, E.2
Montserret, R.3
Wolk, B.4
Hellings, J.A.5
-
18
-
-
4644260669
-
Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A
-
Penin F, Brass V, Appel N, Ramboarina S, Montserret R, et al. (2004) Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A. J Biol Chem 279: 40835-40843.
-
(2004)
J Biol Chem
, vol.279
, pp. 40835-40843
-
-
Penin, F.1
Brass, V.2
Appel, N.3
Ramboarina, S.4
Montserret, R.5
-
19
-
-
19644393931
-
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
-
Tellinghuisen TL, Marcotrigiano J, Rice CM, (2005) Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase. Nature 435: 374-379.
-
(2005)
Nature
, vol.435
, pp. 374-379
-
-
Tellinghuisen, T.L.1
Marcotrigiano, J.2
Rice, C.M.3
-
20
-
-
66149115122
-
Crystal structure of a novel dimeric form of NS5A domain I protein from hepatitis C virus
-
Love RA, Brodsky O, Hickey MJ, Wells PA, Cronin CN, (2009) Crystal structure of a novel dimeric form of NS5A domain I protein from hepatitis C virus. J Virol 83: 4395-4403.
-
(2009)
J Virol
, vol.83
, pp. 4395-4403
-
-
Love, R.A.1
Brodsky, O.2
Hickey, M.J.3
Wells, P.A.4
Cronin, C.N.5
-
21
-
-
27744593476
-
Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein
-
Huang L, Hwang J, Sharma SD, Hargittai MR, Chen Y, et al. (2005) Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein. J Biol Chem 280: 36417-36428.
-
(2005)
J Biol Chem
, vol.280
, pp. 36417-36428
-
-
Huang, L.1
Hwang, J.2
Sharma, S.D.3
Hargittai, M.R.4
Chen, Y.5
-
22
-
-
0038415985
-
Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication
-
Elazar M, Cheong KH, Liu P, Greenberg HB, Rice CM, et al. (2003) Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication. J Virol 77: 6055-6061.
-
(2003)
J Virol
, vol.77
, pp. 6055-6061
-
-
Elazar, M.1
Cheong, K.H.2
Liu, P.3
Greenberg, H.B.4
Rice, C.M.5
-
23
-
-
38349162328
-
Identification of residues required for RNA replication in domains II and III of the hepatitis C virus NS5A protein
-
Tellinghuisen TL, Foss KL, Treadaway JC, Rice CM, (2008) Identification of residues required for RNA replication in domains II and III of the hepatitis C virus NS5A protein. J Virol 82: 1073-1083.
-
(2008)
J Virol
, vol.82
, pp. 1073-1083
-
-
Tellinghuisen, T.L.1
Foss, K.L.2
Treadaway, J.C.3
Rice, C.M.4
-
24
-
-
17144463221
-
Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation
-
Gale M Jr, Blakely CM, Kwieciszewski B, Tan SL, Dossett M, et al. (1998) Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation. Mol Cell Biol 18: 5208-5218.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5208-5218
-
-
Gale Jr., M.1
Blakely, C.M.2
Kwieciszewski, B.3
Tan, S.L.4
Dossett, M.5
-
25
-
-
9144257569
-
Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection
-
Enomoto N, Sakuma I, Asahina Y, Kurosaki M, Murakami T, et al. (1996) Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection. N Engl J Med 334: 77-81.
-
(1996)
N Engl J Med
, vol.334
, pp. 77-81
-
-
Enomoto, N.1
Sakuma, I.2
Asahina, Y.3
Kurosaki, M.4
Murakami, T.5
-
26
-
-
11844280823
-
Hepatitis C virus-related resistance mechanisms to interferon alpha-based antiviral therapy
-
Hofmann WP, Zeuzem S, Sarrazin C, (2005) Hepatitis C virus-related resistance mechanisms to interferon alpha-based antiviral therapy. J Clin Virol 32: 86-91.
-
(2005)
J Clin Virol
, vol.32
, pp. 86-91
-
-
Hofmann, W.P.1
Zeuzem, S.2
Sarrazin, C.3
-
27
-
-
42949130180
-
Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly
-
Appel N, Zayas M, Miller S, Krijnse-Locker J, Schaller T, et al. (2008) Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly. PLoS Pathog 4: e1000035.
-
(2008)
PLoS Pathog
, vol.4
-
-
Appel, N.1
Zayas, M.2
Miller, S.3
Krijnse-Locker, J.4
Schaller, T.5
-
28
-
-
42949145532
-
Regulation of hepatitis C virion production via phosphorylation of the NS5A protein
-
Tellinghuisen TL, Foss KL, Treadaway J, (2008) Regulation of hepatitis C virion production via phosphorylation of the NS5A protein. PLoS Pathog 4: e1000032.
-
(2008)
PLoS Pathog
, vol.4
-
-
Tellinghuisen, T.L.1
Foss, K.L.2
Treadaway, J.3
-
29
-
-
49149113893
-
Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles
-
Masaki T, Suzuki R, Murakami K, Aizaki H, Ishii K, et al. (2008) Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles. J Virol 82: 7964-7976.
-
(2008)
J Virol
, vol.82
, pp. 7964-7976
-
-
Masaki, T.1
Suzuki, R.2
Murakami, K.3
Aizaki, H.4
Ishii, K.5
-
30
-
-
22544470874
-
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
-
Wakita T, Pietschmann T, Kato T, Date T, Miyamoto M, et al. (2005) Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat Med 11: 791-796.
-
(2005)
Nat Med
, vol.11
, pp. 791-796
-
-
Wakita, T.1
Pietschmann, T.2
Kato, T.3
Date, T.4
Miyamoto, M.5
-
31
-
-
23044437222
-
Complete replication of hepatitis C virus in cell culture
-
Lindenbach BD, Evans MJ, Syder AJ, Wolk B, Tellinghuisen TL, et al. (2005) Complete replication of hepatitis C virus in cell culture. Science 309: 623-626.
-
(2005)
Science
, vol.309
, pp. 623-626
-
-
Lindenbach, B.D.1
Evans, M.J.2
Syder, A.J.3
Wolk, B.4
Tellinghuisen, T.L.5
-
32
-
-
0037195180
-
Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees
-
Bukh J, Pietschmann T, Lohmann V, Krieger N, Faulk K, et al. (2002) Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees. Proc Natl Acad Sci U S A 99: 14416-14421.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 14416-14421
-
-
Bukh, J.1
Pietschmann, T.2
Lohmann, V.3
Krieger, N.4
Faulk, K.5
-
33
-
-
0034623816
-
Efficient initiation of HCV RNA replication in cell culture
-
Blight KJ, Kolykhalov AA, Rice CM, (2000) Efficient initiation of HCV RNA replication in cell culture. Science 290: 1972-1974.
-
(2000)
Science
, vol.290
, pp. 1972-1974
-
-
Blight, K.J.1
Kolykhalov, A.A.2
Rice, C.M.3
-
34
-
-
0037369066
-
Viral and cellular determinants of hepatitis C virus RNA replication in cell culture
-
Lohmann V, Hoffmann S, Herian U, Penin F, Bartenschlager R, (2003) Viral and cellular determinants of hepatitis C virus RNA replication in cell culture. J Virol 77: 3007-3019.
-
(2003)
J Virol
, vol.77
, pp. 3007-3019
-
-
Lohmann, V.1
Hoffmann, S.2
Herian, U.3
Penin, F.4
Bartenschlager, R.5
-
35
-
-
0033920304
-
Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3′ nontranslated region are essential for virus replication in vivo
-
Kolykhalov AA, Mihalik K, Feinstone SM, Rice CM, (2000) Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3′ nontranslated region are essential for virus replication in vivo. J Virol 74: 2046-2051.
-
(2000)
J Virol
, vol.74
, pp. 2046-2051
-
-
Kolykhalov, A.A.1
Mihalik, K.2
Feinstone, S.M.3
Rice, C.M.4
-
36
-
-
55749102288
-
Structural determinants for membrane association and dynamic organization of the hepatitis C virus NS3-4A complex
-
Brass V, Berke JM, Montserret R, Blum HE, Penin F, et al. (2008) Structural determinants for membrane association and dynamic organization of the hepatitis C virus NS3-4A complex. Proc Natl Acad Sci U S A 105: 14545-14550.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14545-14550
-
-
Brass, V.1
Berke, J.M.2
Montserret, R.3
Blum, H.E.4
Penin, F.5
-
37
-
-
33748937713
-
Mutations of the Hepatitis C virus protein NS4B on either side of the ER membrane affect the efficiency of subgenomic replicons
-
Lindstrom H, Lundin M, Haggstrom S, Persson MA, (2006) Mutations of the Hepatitis C virus protein NS4B on either side of the ER membrane affect the efficiency of subgenomic replicons. Virus Res 121: 169-178.
-
(2006)
Virus Res
, vol.121
, pp. 169-178
-
-
Lindstrom, H.1
Lundin, M.2
Haggstrom, S.3
Persson, M.A.4
-
38
-
-
0035032237
-
Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations
-
Krieger N, Lohmann V, Bartenschlager R, (2001) Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations. J Virol 75: 4614-4624.
-
(2001)
J Virol
, vol.75
, pp. 4614-4624
-
-
Krieger, N.1
Lohmann, V.2
Bartenschlager, R.3
-
39
-
-
80052283930
-
Development and application of hepatitis C reporter viruses with genotype 1 to 7 core-nonstructural protein 2 (NS2) expressing fluorescent proteins or luciferase in modified JFH1 NS5A
-
Gottwein JM, Jensen TB, Mathiesen CK, Meuleman P, Serre SB, et al. (2011) Development and application of hepatitis C reporter viruses with genotype 1 to 7 core-nonstructural protein 2 (NS2) expressing fluorescent proteins or luciferase in modified JFH1 NS5A. J Virol 85: 8913-8928.
-
(2011)
J Virol
, vol.85
, pp. 8913-8928
-
-
Gottwein, J.M.1
Jensen, T.B.2
Mathiesen, C.K.3
Meuleman, P.4
Serre, S.B.5
-
40
-
-
41949086805
-
Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus
-
Russell RS, Meunier JC, Takikawa S, Faulk K, Engle RE, et al. (2008) Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus. Proc Natl Acad Sci U S A 105: 4370-4375.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 4370-4375
-
-
Russell, R.S.1
Meunier, J.C.2
Takikawa, S.3
Faulk, K.4
Engle, R.E.5
-
41
-
-
33646556662
-
Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras
-
Pietschmann T, Kaul A, Koutsoudakis G, Shavinskaya A, Kallis S, et al. (2006) Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras. Proc Natl Acad Sci U S A 103: 7408-7413.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 7408-7413
-
-
Pietschmann, T.1
Kaul, A.2
Koutsoudakis, G.3
Shavinskaya, A.4
Kallis, S.5
-
42
-
-
70349728564
-
A conserved proline between domains II and III of hepatitis C virus NS5A influences both RNA replication and virus assembly
-
Hughes M, Gretton S, Shelton H, Brown DD, McCormick CJ, et al. (2009) A conserved proline between domains II and III of hepatitis C virus NS5A influences both RNA replication and virus assembly. J Virol 83: 10788-10796.
-
(2009)
J Virol
, vol.83
, pp. 10788-10796
-
-
Hughes, M.1
Gretton, S.2
Shelton, H.3
Brown, D.D.4
McCormick, C.J.5
-
43
-
-
0033545996
-
NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling
-
Tan SL, Nakao H, He Y, Vijaysri S, Neddermann P, et al. (1999) NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling. Proc Natl Acad Sci U S A 96: 5533-5538.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 5533-5538
-
-
Tan, S.L.1
Nakao, H.2
He, Y.3
Vijaysri, S.4
Neddermann, P.5
-
44
-
-
1642375622
-
The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity
-
Macdonald A, Crowder K, Street A, McCormick C, Harris M, (2004) The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity. J Gen Virol 85: 721-729.
-
(2004)
J Gen Virol
, vol.85
, pp. 721-729
-
-
Macdonald, A.1
Crowder, K.2
Street, A.3
McCormick, C.4
Harris, M.5
-
45
-
-
13944263525
-
Mutational analysis of hepatitis C virus nonstructural protein 5A: potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain
-
Appel N, Pietschmann T, Bartenschlager R, (2005) Mutational analysis of hepatitis C virus nonstructural protein 5A: potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain. J Virol 79: 3187-3194.
-
(2005)
J Virol
, vol.79
, pp. 3187-3194
-
-
Appel, N.1
Pietschmann, T.2
Bartenschlager, R.3
-
46
-
-
67650882702
-
Production of infectious genotype 1b virus particles in cell culture and impairment by replication enhancing mutations
-
Pietschmann T, Zayas M, Meuleman P, Long G, Appel N, et al. (2009) Production of infectious genotype 1b virus particles in cell culture and impairment by replication enhancing mutations. PLoS Pathog 5: e1000475.
-
(2009)
PLoS Pathog
, vol.5
-
-
Pietschmann, T.1
Zayas, M.2
Meuleman, P.3
Long, G.4
Appel, N.5
-
48
-
-
37349012884
-
3′ RNA elements in hepatitis C virus replication: kissing partners and long poly(U)
-
You S, Rice CM, (2008) 3′ RNA elements in hepatitis C virus replication: kissing partners and long poly(U). J Virol 82: 184-195.
-
(2008)
J Virol
, vol.82
, pp. 184-195
-
-
You, S.1
Rice, C.M.2
-
49
-
-
67649197727
-
Domain III of NS5A contributes to both RNA replication and assembly of hepatitis C virus particles
-
Hughes M, Griffin S, Harris M, (2009) Domain III of NS5A contributes to both RNA replication and assembly of hepatitis C virus particles. J Gen Virol 90: 1329-1334.
-
(2009)
J Gen Virol
, vol.90
, pp. 1329-1334
-
-
Hughes, M.1
Griffin, S.2
Harris, M.3
-
50
-
-
80052066409
-
Regulation of the production of infectious genotype 1a hepatitis C virus by NS5A domain III
-
Kim S, Welsch C, Yi M, Lemon SM, (2011) Regulation of the production of infectious genotype 1a hepatitis C virus by NS5A domain III. J Virol 85: 6645-6656.
-
(2011)
J Virol
, vol.85
, pp. 6645-6656
-
-
Kim, S.1
Welsch, C.2
Yi, M.3
Lemon, S.M.4
-
51
-
-
77951979673
-
Role of annexin A2 in the production of infectious hepatitis C virus particles
-
Backes P, Quinkert D, Reiss S, Binder M, Zayas M, et al. (2010) Role of annexin A2 in the production of infectious hepatitis C virus particles. J Virol 84: 5775-5789.
-
(2010)
J Virol
, vol.84
, pp. 5775-5789
-
-
Backes, P.1
Quinkert, D.2
Reiss, S.3
Binder, M.4
Zayas, M.5
-
52
-
-
0030571476
-
Characterization of the nuclear localization signal and subcellular distribution of hepatitis C virus nonstructural protein NS5A
-
Ide Y, Zhang L, Chen M, Inchauspe G, Bahl C, et al. (1996) Characterization of the nuclear localization signal and subcellular distribution of hepatitis C virus nonstructural protein NS5A. Gene 182: 203-211.
-
(1996)
Gene
, vol.182
, pp. 203-211
-
-
Ide, Y.1
Zhang, L.2
Chen, M.3
Inchauspe, G.4
Bahl, C.5
-
53
-
-
80052123459
-
Differential efficacy of protease inhibitors against HCV genotypes 2a, 3a, 5a, and 6a NS3/4A protease recombinant viruses
-
Gottwein JM, Scheel TK, Jensen TB, Ghanem L, Bukh J, (2011) Differential efficacy of protease inhibitors against HCV genotypes 2a, 3a, 5a, and 6a NS3/4A protease recombinant viruses. Gastroenterology 141: 1067-1079.
-
(2011)
Gastroenterology
, vol.141
, pp. 1067-1079
-
-
Gottwein, J.M.1
Scheel, T.K.2
Jensen, T.B.3
Ghanem, L.4
Bukh, J.5
-
54
-
-
47749092840
-
NS3 helicase domains involved in infectious intracellular hepatitis C virus particle assembly
-
Ma Y, Yates J, Liang Y, Lemon SM, Yi M, (2008) NS3 helicase domains involved in infectious intracellular hepatitis C virus particle assembly. J Virol 82: 7624-7639.
-
(2008)
J Virol
, vol.82
, pp. 7624-7639
-
-
Ma, Y.1
Yates, J.2
Liang, Y.3
Lemon, S.M.4
Yi, M.5
-
55
-
-
78651252353
-
Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly
-
Jirasko V, Montserret R, Lee JY, Gouttenoire J, Moradpour D, et al. (2010) Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly. PLoS Pathog 6: e1001233.
-
(2010)
PLoS Pathog
, vol.6
-
-
Jirasko, V.1
Montserret, R.2
Lee, J.Y.3
Gouttenoire, J.4
Moradpour, D.5
-
56
-
-
78650062692
-
Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins
-
Ma Y, Anantpadma M, Timpe JM, Shanmugam S, Singh SM, et al. (2011) Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins. J Virol 85: 86-97.
-
(2011)
J Virol
, vol.85
, pp. 86-97
-
-
Ma, Y.1
Anantpadma, M.2
Timpe, J.M.3
Shanmugam, S.4
Singh, S.M.5
-
57
-
-
79955778897
-
The subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 protein
-
Tedbury P, Welbourn S, Pause A, King B, Griffin S, et al. (2011) The subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 protein. J Gen Virol 92: 819-830.
-
(2011)
J Gen Virol
, vol.92
, pp. 819-830
-
-
Tedbury, P.1
Welbourn, S.2
Pause, A.3
King, B.4
Griffin, S.5
-
58
-
-
78951472458
-
Hepatitis C Virus NS2 Coordinates Virus Particle Assembly through Physical Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes
-
Stapleford KA, Lindenbach BD, (2011) Hepatitis C Virus NS2 Coordinates Virus Particle Assembly through Physical Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes. J Virol 85: 1706-1717.
-
(2011)
J Virol
, vol.85
, pp. 1706-1717
-
-
Stapleford, K.A.1
Lindenbach, B.D.2
-
59
-
-
34648827871
-
Alanine Scanning of the Hepatitis C Virus Core Protein Reveals Numerous Residues Essential for Infectious Virus Production
-
Murray CL, Jones CT, Tassello J, Rice CM, (2007) Alanine Scanning of the Hepatitis C Virus Core Protein Reveals Numerous Residues Essential for Infectious Virus Production. J Virol 81: 10220-10231.
-
(2007)
J Virol
, vol.81
, pp. 10220-10231
-
-
Murray, C.L.1
Jones, C.T.2
Tassello, J.3
Rice, C.M.4
-
60
-
-
35648963197
-
Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses
-
Gottwein JM, Scheel TK, Hoegh AM, Lademann JB, Eugen-Olsen J, et al. (2007) Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses. Gastroenterology 133: 1614-1626.
-
(2007)
Gastroenterology
, vol.133
, pp. 1614-1626
-
-
Gottwein, J.M.1
Scheel, T.K.2
Hoegh, A.M.3
Lademann, J.B.4
Eugen-Olsen, J.5
-
61
-
-
79952416361
-
Efficient culture adaptation of hepatitis C virus intergenotypic JFH1-based Core-NS2 recombinants by using previously identified mutations
-
Scheel TK, Gottwein JM, Carlsen TH, Li YP, Jensen TB, et al. (2011) Efficient culture adaptation of hepatitis C virus intergenotypic JFH1-based Core-NS2 recombinants by using previously identified mutations. J Virol 85: 2891-2906.
-
(2011)
J Virol
, vol.85
, pp. 2891-2906
-
-
Scheel, T.K.1
Gottwein, J.M.2
Carlsen, T.H.3
Li, Y.P.4
Jensen, T.B.5
-
62
-
-
2142738304
-
WebLogo: a sequence logo generator
-
Crooks GE, Hon G, Chandonia JM, Brenner SE, (2004) WebLogo: a sequence logo generator. Genome Res 14: 1188-1190.
-
(2004)
Genome Res
, vol.14
, pp. 1188-1190
-
-
Crooks, G.E.1
Hon, G.2
Chandonia, J.M.3
Brenner, S.E.4
-
63
-
-
0025008168
-
Sequence logos: a new way to display consensus sequences
-
Schneider TD, Stephens RM, (1990) Sequence logos: a new way to display consensus sequences. Nucleic Acids Res 18: 6097-6100.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 6097-6100
-
-
Schneider, T.D.1
Stephens, R.M.2
|