Exercise response in hypertrophic cardiomyopathy: Blunted left ventricular deformational and twisting reserve with altered systolic-diastolic coupling

Circulation: Cardiovascular Imaging

Volumn 5, Issue 3, 2012, Pages 324-332

  Soullier, Camille ^a   Obert, Philippe ^b   Doucende, Gregory ^b   Nottin, Stéphane ^b   Cade, Stéphane ^a   Perez Martin, Antonia ^c   Messner Pellenc, Patrick ^a   Schuster, Iris ^c  

^a NÎMES UNIVERSITY HOSPITAL   (France)

^b UNIVERSITY OF AVIGNON   (France)

^c University of Montpellier 1   (France)

Author keywords

Exercise; Left ventricular hypertrophy; Speckle tracking; Torsion; Untwist

Indexed keywords

ADULT; ARTICLE; BLUNTED LEFT VENTRICULAR DEFORMATIONAL; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; EXERCISE; EXERCISE ELECTROCARDIOGRAPHY; FEMALE; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE FUNCTION; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; LONGITUDINAL STUDY; MALE; MECHANICAL TORSION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SYSTOLIC BLOOD PRESSURE;

ANALYSIS OF VARIANCE; CARDIOMYOPATHY, HYPERTROPHIC; DIASTOLE; EXERCISE; EXERCISE TEST; FEMALE; HEART VENTRICLES; HUMANS; MALE; MIDDLE AGED; REST; SYSTOLE; TIME FACTORS; TORSION ABNORMALITY; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84863681147     PISSN: 19419651     EISSN: 19420080     Source Type: Journal    
DOI: 10.1161/CIRCIMAGING.111.968859     Document Type: Article

References (34)

1. Maron BJ. Hypertrophic cardiomyopathy: a systematic review. JAMA. 2002;287:1308-1320. (Pubitemid 34250486)
2. Nagueh SF, Mahmarian JJ. Noninvasive cardiac imaging in patients with hypertrophic cardiomyopathy. J Am Coll Cardiol. 2006;48:2410-2422. (Pubitemid 44881224)
3. Afonso LC, Bernal J, Bax JJ, Abraham TP. Echocardiography in hypertrophic cardiomyopathy: the role of conventional and emerging technologies. J Am Coll Cardiol Cardiovasc Imaging. 2008;1:787-800.
4. Young AA, Kramer CM, Ferrari VA, Axel L, Reichek N. Three-dimensional left ventricular deformation in hypertrophic cardiomyopathy. Circulation. 1994;90:854-867. (Pubitemid 24242755)
5. Notomi Y, Martin-Miklovic MG, Oryszak SJ, Shiota T, Deserranno D, Popovic ZB, Garcia MJ, Greenberg NL, Thomas JD. Enhanced ventricular untwisting during exercise: a mechanistic manifestation of elastic recoil described by Doppler tissue imaging. Circulation. 2006;113: 2524-2533. (Pubitemid 43948031)
6. Carasso S, Yang H, Woo A, Vannan MA, Jamorski M, Wigle ED, Rakowski H. Systolic myocardial mechanics in hypertrophic cardiomyopathy: novel concepts and implications for clinical status. JAmSoc Echocardiogr. 2008;21:675-683.
7. Serri K, Reant P, Lafitte M, Berhouet M, Le Bouffos V, Roudaut R, Lafitte S. Global and regional myocardial function quantification by two-dimensional strain: application in hypertrophic cardiomyopathy. J Am Coll Cardiol. 2006;47:1175-1181.
8. Popovic ZB, Kwon DH, Mishra M, Buakhamsri A, Greenberg NL, Thamilarasan M, Flamm SD, Thomas JD, Lever HM, Desai MY. Association between regional ventricular function and myocardial fibrosis in hypertrophic cardiomyopathy assessed by speckle tracking echocardiography and delayed hyperenhancement magnetic resonance imaging. JAm Soc Echocardiogr. 2008;21:1299-1305.
9. Sun JP, Stewart WJ, Yang XS, Donnell RO, Leon AR, Felner JM, Thomas JD, Merlino JD. Differentiation of hypertrophic cardiomyopathy and cardiac amyloidosis from other causes of ventricular wall thickening by two-dimensional strain imaging echocardiography. Am J Cardiol. 2009;103:411-415.
10. Wang J, Buergler JM, Veerasamy K, Ashton YP, Nagueh SF. Delayed untwisting: the mechanistic link between dynamic obstruction and exercise tolerance in patients with hypertrophic obstructive cardiomyopathy. J Am Coll Cardiol. 2009;54:1326-1334.
11. Van Dalen BM, Kauer F, Soliman OI, Vletter WB, Michels M, ten Cate FJ, Geleijnse ML. Influence of the pattern of hypertrophy on left ventricular twist in hypertrophic cardiomyopathy. Heart. 2009;95:657-661.
12. Abozguia K, Nallur-Shivu G, Phan TT, Ahmed I, Kalra R, Weaver RA, McKenna WJ, Sanderson JE, Elliott P, Frenneaux MP. Left ventricular strain and untwist in hypertrophic cardiomyopathy: relation to exercise capacity. Am Heart J. 2010;159:825-832.
13. Burns AT, La Gerche A, Prior DL, Macisaac AI. Left ventricular untwisting is an important determinant of early diastolic function. JAm Coll Cardiol Cardiovasc Imaging. 2009;2:709-716.
14. Marwick TH. The deconvolution of diastole. J Am Coll Cardiol. 2009; 54:47-48.
15. Marwick TH, Leano RL, Brown J, Sun JP, Hoffmann R, Lysyansky P, Becker M, Thomas JD. Myocardial strain measurement with 2-dimensional speckle-tracking echocardiography: definition of normal range. J Am Coll Cardiol Cardiovasc Imaging. 2009;2:80-84.
16. Helle-Valle T, Crosby J, Edvardsen T, Lyseggen E, Amundsen BH, Smith HJ, Rosen BD, Lima JA, Torp H, Ihlen H, Smiseth OA. New noninvasive method for assessment of left ventricular rotation: speckle tracking echo-cardiography. Circulation. 2005;112:3149-3156.
17. Notomi Y, Lysyansky P, Setser RM, Shiota T, Popovic ZB, Martin-Miklovic MG, Weaver JA, Oryszak SJ, Greenberg NL, White RD, Thomas JD. Measurement of ventricular torsion by two-dimensional ultrasound speckle tracking imaging. J Am Coll Cardiol. 2005;45:2034-2041. (Pubitemid 40814128)
18. Doucende G, Schuster I, Rupp T, Startun A, Dauzat M, Obert P, Nottin S. Kinetics of left ventricular strains and torsion during incremental exercise in healthy subjects: the key role of torsional mechanics for systolic-diastolic coupling. Circ Cardiovasc Imaging. 2010;3:586-594.
19. Esch BT, Scott JM, Warburton DE, Thompson R, Taylor D, Cheng Baron J, Paterson I, Haykowsky MJ. Left ventricular torsion and untwisting during exercise in heart transplant recipients. J Physiol. 2009;587: 2375-2386.
20. Tan YT, Wenzelburger F, Lee E, Heatlie G, Leyva F, Patel K, Frenneaux M, Sanderson JE. The pathophysiology of heart failure with normal ejection fraction. J Am Coll Cardiol. 2009;54:36-46.
21. Maron MS, Olivotto I, Betocchi S, Casey SA, Lesser JR, Losi MA, Cecchi F, Maron BJ. Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy. N Engl J Med. 2003; 348:295-303. (Pubitemid 36119984)
22. ACCF/ASE/ACEP/ASNC/SCAI/SCCT/SCMR 2007 appropriateness criteria for transthoracic and transesophageal echocardiography. JAm Coll Cardiol. 2007;50:187-204.
23. van Dalen BM, Vletter WB, Soliman OI, ten Cate FJ, Geleijnse ML. Importance of transducer position in the assessment of apical rotation by speckle tracking echocardiography. J Am Soc Echocardiogr. 2008;21: 895-898.
24. Lumens J, Delhaas T, Arts T, Cowan BR, Young AA. Impaired subendocardial contractile myofiber function in asymptomatic aged humans, as detected using MRI. Am J Physiol Heart Circ Physiol. 2006;291: H1573-H1579. (Pubitemid 44497660)
25. Beyar R, Sideman S. Effect of the twisting motion on the nonuniformities of transmyocardial fiber mechanics and energy demand. IEEE Trans Biomed Eng. 1985;32:764-769. (Pubitemid 16243547)
26. Burns AT, McDonald IG, Thomas JD, Macisaac A, Prior D. Doin' the twist: new tools for an old concept of myocardial function. Heart. 2008; 94:978-983. (Pubitemid 352039877)
27. Taber LA, Yang M, Podszus WW. Mechanics of ventricular torsion. J Biomech. 1996;29:745-752. (Pubitemid 26137409)
28. Chang SA, Kim HK, Kim DH, Kim JC, Kim YJ, Kim HC, Sohn DW, Oh BH, Park YB. Left ventricular twist mechanics in patients with apical hypertrophic cardiomyopathy: assessment with 2D speckle tracking echo-cardiography. Heart. 2010;96:49-55.
29. Lele SS, Thomson HL, Seo H, Belenkie I, McKenna WJ, Frenneaux MP. Exercise capacity in hypertrophic cardiomyopathy. Circulation. 1995;92: 2886-2894.
30. Notomi Y, Popovic ZB, Yamada H, Wallick DW, Martin MG, Oryszak SJ, Shiota T, Greenberg NL, Thomas JD. Ventricular untwisting: a temporal link between left ventricular relaxation and suction. Am J Physiol Heart Circ Physiol. 2008;294:H505-H513.
31. LeWinter MM, Granzier H. Cardiac titin: a multifunctional giant. Circulation. 2010;121:2137-2145.
32. Nagueh SF, Shah G, Wu Y, Torre-Amione G, King NM, Lahmers S, Witt CC, Becker K, Labeit S, Granzier HL. Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy. Circulation. 2004;110:155-162. (Pubitemid 38924583)
33. Dong SJ, Hees PS, Siu CO, Weiss JL, Shapiro EP. MRI assessment of LV relaxation by untwisting rate: a new isovolumic phase measure of tau. Am J Physiol Heart Circ Physiol. 2001;281:H2002-H2009.
34. Moon MR, Ingels NB Jr, Daughters GT II, Stinson EB, Hansen DE, Miller DC. Alterations in left ventricular twist mechanics with inotropic stimulation and volume loading in human subjects. Circulation. 1994;89:142-150. (Pubitemid 24026484)