Phase stability and rapid consolidation of hydroxyapatite-zirconia nano-coprecipitates made using continuous hydrothermal flow synthesis

Journal of Biomaterials Applications

Volumn 27, Issue 1, 2012, Pages 79-90

  Chaudhry, Aqif A ^a,b   Yan, Haixue ^c   Viola, Giuseppe ^c   Reece, Mike J ^c   Knowles, Jonathan C ^d,e   Gong, Kenan ^a   Rehman, Ihtesham ^f   Darr, Jawwad A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Process and Energy Systems Engineering Center PRESTIGE   (Pakistan)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e Dankook University   (South Korea)

^f UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

hydrothermal flow; Hydroxyapatite; nanostructure; spark plasma sintering; zirconia

Indexed keywords

CO-PRECIPITATED; CO-PRECIPITATES; ELEVATED TEMPERATURE; FLOW SYNTHESIS; HYDROTHERMAL FLOW; HYDROTHERMAL ROUTES; IN-SITU; LOAD-BEARING; MECHANICAL TESTS; MOLAR RATIO; NANO-SIZED HYDROXYAPATITE; PARTICLE SIZE AND MORPHOLOGIES; POWDER MIXTURES; PROCESSING CONDITION; SINTERED DENSITY; SINTERED SAMPLES; SPARK PLASMA; SUPERHEATED WATER; VARIABLE TEMPERATURE; WEIBULL MODULUS; ZIRCONIA NANOPARTICLES;

CALCIUM; HYDROTHERMAL SYNTHESIS; HYDROXYAPATITE; NANOSTRUCTURES; PHASE STABILITY; SPARK PLASMA SINTERING; TRANSMISSION ELECTRON MICROSCOPY; WEIBULL DISTRIBUTION; X RAY DIFFRACTION;

ZIRCONIA;

HYDROXYAPATITE; NANOPARTICLE; ZIRCONIUM; ZIRCONIUM OXIDE;

ARTICLE; CHEMISTRY; PARTICLE SIZE; POWDER DIFFRACTION; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

DURAPATITE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARTICLE SIZE; POWDER DIFFRACTION; ZIRCONIUM;

EID: 84863677973     PISSN: 08853282     EISSN: 15308022     Source Type: Journal    
DOI: 10.1177/0885328212444483     Document Type: Article

References (88)

1. Hench LL. Biomaterials: a forecast for the future. Biomaterials. 1998 ; 19: 1419-1419
2. Hench LL. Bioceramics. J Am Ceram Soc. 1998 ; 81: 1705-1705
3. Hench LL. The challenge of orthopaedic materials. Curr Orthopaed. 2000 ; 14: 7-7
4. Katti KS. Biomaterials in total joint replacement. Colloids Surf B. 2004 ; 39: 133-133
5. Caria PHF, Kawachi EY, Bertran CA, et al. Biological assessment of porous-implant hydroxyapatite combined with periosteal grafting in maxillary defects. J Oral Maxillofacial Surg. 2007 ; 65: 847-847
6. Storck C, Brockmann M, Schnellmann E, et al. Functional outcome of vocal fold medialization thyroplasty with a hydroxyapatite implant. Laryngoscope. 2007 ; 117: 1118-1118
7. Heimann RB, Vu TA. Effect of CaO on thermal decomposition during sintering of composite hydroxyapatite-zirconia mixtures for monolithic bioceramic implants. J Mater Sci Lett. 1997 ; 16: 437-437
8. Roeder RK, Sproul MM, Turner CH. Hydroxyapatite whiskers provide improved mechanical properties in reinforced polymer composites. J Biomed Mater Res. 2003 ; 67A: 801-801
9. White AA, Best SM, Kinloch IA. Hydroxyapatite-carbon nanotube composites for biomedical applications: A review. Int J Appl Ceram Technol. 2007 ; 4: 1-1
10. Oktar FN, Meydanoglu O, Goller G, et al 2006:
11. Kong YM, Bae CJ, Lee SH, et al. Improvement in biocompatibility of ZrO2-Al2O3 nano-composite by addition of HA. Biomaterials. 2005 ; 26: 509-509
12. Kim HW, Koh YH, Seo SB, et al. Properties of fluoridated hydroxyapatite-alumina biological composites densified with addition of CaF2. Mater Sci Eng C. 2003 ; 23: 515-515
13. Viswanath B, Ravishankar N. Interfacial reactions in hydroxyapatite/ alumina nanocomposites. Scr Mater. 2006 ; 55: 863-863
14. Ahn ES, Gleason NJ, Ying JY. The effect of zirconia reinforcing agents on the microstructure and mechanical properties of hydroxyapatite-based nanocomposites. J Am Ceram Soc. 2005 ; 88: 3374-3374
15. Balamurugan A, Balossier G, Kannan S, et al. Electrochemical and structural characterisation of zirconia reinforced hydroxyapatite bioceramic sol-gel coatings on surgical grade 316L SS for biomedical applications. Ceram Int. 2007 ; 33: 605-605
16. Suzuki T, Fujibayashi S, Nakagawa Y, et al. Ability of zirconia double coated with titanium and hydroxyapatite to bond to bone under load-bearing conditions. Biomaterials. 2006 ; 27: 996-996
17. Evis Z, Sato M, Webster TJ. Increased osteoblast adhesion on nanograined hydroxyapatite and partially stabilized zirconia composites. J Biomed Mater Res. 2006 ; 78A: 500-500
18. Chiu CY, Hsu HC, Tuan WH. Effect of zirconia addition on the microstructural evolution of porous hydroxyapatite. Ceram Int. 2007 ; 33: 715-715
19. Mansur C, Pope M, Pascucci MR, et al. Zirconia-calcium phosphate composites for bone replacement. Ceram Int. 1998 ; 24: 77-77
20. Kumar R, Prakash KH, Cheang P, et al. Microstructure and mechanical properties of spark plasma sintered zirconia-hydroxyapatite nano-composite powders. Acta Mater. 2005 ; 53: 2327-2327
21. Guo HB, Khor KA, Boey YC, et al. Laminated and functionally graded hydroxyapatite/yttria stabilized tetragonal zirconia composites fabricated by spark plasma sintering. Biomaterials. 2003 ; 24: 667-667
22. Zhang JX, Iwasa M, Kotobuki N, et al. Fabrication of hydroxyapatite- zirconia composites for orthopedic applications. J Am Ceram Soc. 2006 ; 89: 3348-3348
23. Adolfsson E, Alberius-Henning P, Hermansson L. Phase analysis and thermal stability of hot isostatically pressed zirconia-hydroxyapatite composites. J Am Ceram Soc. 2000 ; 83: 2798-2798
24. Matsuno T, Morita M, Watanabe K, et al. Strength of bond to bone and cytotoxicity of sintered bodies of hydroxyapatite/zirconia composite particles. J Mater Sci-Mater Med. 2003 ; 14: 547-547
25. Rapacz-Kmita A, Slosarczyk A, Paszkiewicz Z, et al. Phase stability of hydroxyapatite-zirconia (HAp-ZrO2) composites for bone replacement. J Mol Struct. 2004 ; 704: 333-333
26. Sung YM, Shin YK, Ryu JJ. Preparation of hydroxyapatite/zirconia bioceramic nanocomposites for orthopaedic and dental prosthesis applications. Nanotechnology. 2007 ; 18:
27. Whited BM, Skrtic D, Love BJ, et al. Osteoblast response to zirconia-hybridized pyrophosphate-stabilized amorphous calcium phosphate. J Biomed Mater Res. 2006 ; 76A: 596-596
28. Silva VV, Lameiras FS, Lobato ZIP. Biological reactivity of zirconia-hydroxyapatite composites. J Biomed Mater Res. 2002 ; 63: 583-583
29. Sung YM, Kim DH. Crystallization characteristics of yttria-stabilized zirconia/hydroxyapatite composite nanopowder. J Cryst Growth. 2003 ; 254: 411-411
30. Silva VV, Lameiras FS, Domingues RZ. Synthesis and characterization of calcia partially stabilized zirconia-hydroxyapatite powders prepared by co-precipitation method. Ceram Int. 2001 ; 27: 615-615
31. Silva VV, Lameiras FS, Domingues RZ. Microstructural and mechanical study of zirconia-hydroxyapatite (ZH) composite ceramics for biomedical applications. Compos Sci Technol. 2001 ; 61: 301-301
32. Silva VV, Lameiras FS. Synthesis and characterization of composite powders of partially stabilized zirconia and hydroxyapatite. Mater Charact. 2000 ; 45: 51-51
33. Silva VV, Domingues RZ. Hydroxyapatite-zirconia composites prepared by precipitation method. J Mater Sci-Mater Med. 1997 ; 8: 907-907
34. Knowles JC, Talal S, Santos JD. Sintering effects in a glass reinforced hydroxyapatite. Biomaterials. 1996 ; 17: 1437-1437
35. Kobayashi S, Kawai W, Wakayama S. The effect of pressure during sintering on the strength and the fracture toughness of hydroxyapatite ceramics. J Mater Sci-Mater Med. 2006 ; 17: 1089-1089
36. Kothapalli C, Wei M, Vasiliev A, et al. Influence of temperature and concentration on the sintering behavior and mechanical properties of hydroxyapatite. Acta Mater. 2004 ; 52: 5655-5655
37. Delgado JA, Morejon L, Martinez S, et al. Zirconia-toughened hydroxyapatite ceramic obtained by wet sintering. J Mater Sci-Mater Med. 1999 ; 10: 715-715
38. Kim HW, Kong YM, Koh YH, et al. Pressureless sintering and mechanical and biological properties of fluor-hydroxyapatite composites with zirconia. J Am Ceram Soc. 2003 ; 86: 2019-2019
39. Barralet JE, Best SM, Bonfield W. Effect of sintering parameters on the density and microstructure of carbonate hydroxyapatite. J Mater Sci-Mater Med. 2000 ; 11: 719-719
40. Pramanik S, Agarwal AK, Rai KN, et al. Development of high strength hydroxyapatite by solid-state-sintering process. Ceram Int. 2007 ; 33: 419-419
41. Mostafa NY. Characterization, thermal stability and sintering of hydroxyapatite powders prepared by different routes. Mater Chem Phys. 2005 ; 94: 333-333
42. Nayar S, Sinha MK, Basu D, et al. Synthesis and sintering of biomimetic hydroxyapatite nanoparticles for biomedical applications. J Mater Sci-Mater Med. 2006 ; 17: 1063-1063
43. Zhang JX, Tanaka H, Ye F, et al. Colloidal processing and sintering of hydroxyapatite. Mater Chem Phys. 2007 ; 101: 69-69
44. Cai S, Yu XZ, Xiao ZY, et al. Synthesis and sintering of nanocrystalline hydroxyapatite powders by gelatin-based precipitation method. Ceram Int. 2007 ; 33: 193-193
45. Guo LH, Huang M, Zhang XD. Effects of sintering temperature on structure of hydroxyapatite studied with Rietveld method. J Mater Sci-Mater Med. 2003 ; 14: 817-817
46. Laquerriere P, Grandjean-Laquerriere A, Guenounou M, et al. Correlation between sintering temperature of hydroxyapatite particles and the production of inflammatory cytokines by human monocytes. Colloids Surf B. 2003 ; 30: 207-207
47. Barralet JE, Fleming GJP, Campion C, et al. Formation of translucent hydroxyapatite ceramics by sintering in carbon dioxide atmospheres. J Mater Sci. 2003 ; 38: 3979-3979
48. Kim HW, Noh YJ, Koh YH, et al. Effect of CaF2 on densification and properties of hydroxyapatite-zirconia composites for biomedical applications. Biomaterials. 2002 ; 23: 4113-4113
49. Rao RR, Kannan TS. Synthesis and sintering of hydroxyapatite-zirconia composites. Mater Sci Eng C. 2002 ; 20: 187-187
50. Towler MR, Gibson IR, Best SM. Novel processing of hydroxyapatite- zirconia composites using nano-sized particles. J Mater Sci Lett. 2000 ; 19: 2209-2209
51. Evis Z, Doremus RH. Effect of ZrF4 on hot-pressed hydroxyapatite/ monoclinic zirconia composites. Scr Mater. 2007 ; 56: 53-53
52. Inuzuka M, Nakamura S, Kishi S, et al. Hydroxyapatite-doped zirconia for preparation of biomedical composites ceramics. Solid State Ionics. 2004 ; 172: 509-509
53. Li J, Liao H, Hermansson L. Sintering of partially-stabilized zirconia and partially-stabilized zirconia-hydroxyapatite composites by hot isostatic pressing and pressureless sintering. Biomaterials. 1996 ; 17: 1787-1787
54. Matsumoto T, Okazaki M, Inoue M, et al. Biodegradation of carbonate apatite/collagen composite membrane and its controlled release of carbonate apatite. J Biomed Mater Res. 2002 ; 60: 651-651
55. Matsuno T, Watanabe K, Ono K, et al. Microstructure and mechanical properties of sintered body of zirconia coated hydroxyapatite particles. J Mater Sci Lett. 2000 ; 19: 573-573
56. Chaudhry AA, Yan H, Gong K, et al. High-strength nanograined and translucent hydroxyapatite monoliths via continuous hydrothermal synthesis and optimized spark plasma sintering. Acta Biomater. 2011 ; 7: 791-791
57. Munir ZA, Anselmi-Tamburini U, Ohyanagi M. The effect of electric field and pressure on the synthesis and consolidation of materials: A review of the spark plasma sintering method. J Mater Sci. 2006 ; 41: 763-763
58. Gu YW, Loh NH, Khor KA, et al. Spark plasma sintering of hydroxyapatite powders. Biomaterials. 2002 ; 23: 37-37
59. Xu JL, Khor KA, Gu YW, et al. Radio frequency (rf) plasma spheroidized HA powders: powder characterization and spark plasma sintering behavior. Biomaterials. 2005 ; 26: 2197-2197
60. Omori M, Onoki T, Hashida T, et al. Low temperature synthesis of hydroxyapatite from CaHPO4 center dot 2H2O and Ca(OH)2 based on effect of the spark plasma system (SPS). Ceram Int. 2006 ; 32: 617-617
61. Guo XY, Xiao P, Liu J, et al. Fabrication of nanostructured hydroxyapatite via hydrothermal synthesis and spark plasma sintering. J Am Ceram Soc. 2005 ; 88: 1026-1026
62. Xu JL, Khor KA. Chemical analysis of silica doped hydroxyapatite biomaterials consolidated by a spark plasma sintering method. J Inorg Biochem. 2007 ; 101: 187-187
63. Xu JL, Khor KA, Kumar R. Physicochemical differences after densifying radio frequency plasma sprayed hydroxyapatite powders using spark plasma and conventional sintering techniques. Mater Sci Eng A. 2007 ; 457: 24-24
64. Watanabe Y, Ikoma T, Monkawa A, et al. Fabrication of transparent hydroxyapatite sintered body with high crystal orientation by pulse electric current sintering. J Am Ceram Soc. 2005 ; 88: 243-243
65. Khalil KA, Kim HY, Kim SW, et al. Observation of toughness improvement of the hydroxyapatite bioceramics densified using high-frequency induction heat sintering. Int J Appl Ceram Technol. 2007 ; 4: 30-30
66. Kumar R, Cheang P, Khor KA. Spark plasma sintering and in vitro study of ultra-fine HA and ZrO2-HA powders. J Mater Process Technol. 2003 ; 140: 420-420
67. Miao XG, Chen YM, Guo HB, et al. Spark plasma sintered hydroxyapatite-yttria stabilized zirconia composites. Ceram Int. 2004 ; 30: 1793-1793
68. Shen ZJ, Adolfsson E, Nygren M, et al. Dense hydroxyapatite-zirconia ceramic composites with high strength for biological applications. Adv Mater. 2001 ; 13: 214-214
69. Boldrin P, Hebb AK, Chaudhry AA, et al. Direct synthesis of nanosized NiCo2O4 spinel and related compounds via continuous hydrothermal synthesis. Ind Eng Chem Res. 2007 ; 46: 4830-4830
70. Cabanas A, Darr JA, Lester E, et al. A continuous and clean one-step synthesis of nano-particulate Ce1-xZrxO2 solid solutions in near-critical water. Chem Commun. 2000 ; 901:
71. Cabanas A, Darr JA, Lester E, et al. Continuous hydrothermal synthesis of inorganic materials in a near-critical water flow reactor; the one-step synthesis of nano-particulate Ce1-xZrxO2 (x=0-1) solid solutions. J Mater Chem. 2001 ; 11: 561-561
72. Weng XL, Boldrin P, Abrahams I, et al. Direct syntheses of mixed ion and electronic conductors La4Ni3O10 and 3Ni2O7 from nanosized coprecipitates. Chem Mater. 2007 ; 19: 4382-4382
73. Weng XL, Boldrin P, Abrahams I, et al. Direct syntheses of Lan+1NinO3n+1 phases (n=1, 2, 3 and infinity) from nanosized co-crystallites. J Solid State Chem. 2008 ; 181: 1123-1123
74. Weng XL, Cockcroft JK, Hyett G, et al. High-Throughput Continuous Hydrothermal Synthesis of an Entire Nanoceramic Phase Diagram. J Comb Chem. 2009 ; 11: 829-829
75. Weng XL, Perston B, Wang XZ, et al. Synthesis and characterization of doped nano-sized ceria-zirconia solid solutions. Appl Catal B. 2009 ; 90: 405-405
76. Weng XL, Brett D, Yufit V, et al. Highly conductive low nickel content nano-composite dense cermets from nano-powders made via a continuous hydrothermal synthesis route. Solid State Ionics. 2010 ; 181: 827-827
77. Zhang Z, Goodall JBM, Morgan DJ, et al. Photocatalytic activities of N-doped nano-titanias and titanium nitride. J Eur Ceram Soc. 2009 ; 29: 2343-2343
78. Zhang Z, Goodall JBM, Brown S, et al. Continuous hydrothermal synthesis of extensive 2D sodium titanate (Na2Ti3O7) nano-sheets. Dalton Trans. 2010 ; 39: 711-711
79. Chaudhry AA, Haque S, Kellici S, et al. Instant nano-hydroxyapatite: a continuous and rapid hydrothermal synthesis. Chem Commun. 2006 ;: 2286-2286
80. Chaudhry AA, Goodall J, Vickers M, et al. Synthesis and Characterisation of Magnesium Substituted Calcium Phosphate Bioceramic Nanoparticles made via Continuous Hydrothermal Flow Synthesis. J Mater Chem. 2008 ; 18: 5900-5900
81. Huang J, Hing K Biomaterials Testing Laboratory, Mechanical Testing Facility, IRC in Biomedical Materials. Queen Mary University of London ; 2002:
82. Kim BN, Morita K, Lim JH, et al. Effects of Preheating of Powder Before Spark Plasma Sintering of Transparent MgAl2O4 Spinel. J Am Ceram Soc. 2010 ; 93: 2158-2158
83. Zhang H, Darvell BW. Morphology and structural characteristics of hydroxyapatite whiskers: Effect of the initial Ca concentration, Ca/P ratio and pH. Acta Biomater. 2011 ; 7: 2960-2960
84. Ghosh A, Suri AK, Pandey M, et al. Nanocrystalline zirconia-yttria system-a Raman study. Mater Lett. 2006 ; 60: 1170-1170
85. Siu GG, Stokes MJ, Liu YL. Variation of fundamental and higher-order Raman spectra of ZrO2 nanograins with annealing temperature. Phys Rev B. 1999 ; 59: 3173-3173
86. Ishikawa K, Ducheyne P, Radin S. Determination of the Ca/P Ratio in Calcium-Deficient Hydroxyapatite Using X-Ray-Diffraction Analysis. J Mater Sci-Mater Med. 1993 ; 4: 165-165
87. Stubican VS, Ray SP. Phase-Equilibria and Ordering in System Zro2-Cao. J Am Ceram Soc. 1977 ; 60: 534
88. Nayak Y, Rana R, Pratihar S, et al. Pressureless sintering of dense hydroxyapatite-zirconia composites. J Mater Sci-Mater Med. 2008 ; 19: 2437-2437