Functional polymorphism of the dopamine β-hydroxylase gene is associated with increased risk of disulfiram-induced adverse effects in alcohol-dependent patients

Journal of Clinical Psychopharmacology

Volumn 32, Issue 4, 2012, Pages 578-580

  Mutschler, Jochen ^a,b   Abbruzzese, Elvira ^a   Witt, Stephanie H ^b   Dirican, Gülseren ^b   Nieratschker, Vanessa ^b   Frank, Josef ^b   Grosshans, Martin ^b   Rietschel, Marcella ^b   Kiefer, Falk ^b  

^a UNIVERSITY HOSPITAL OF PSYCHIATRY   (Switzerland)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACAMPROSATE; ALDEHYDE DEHYDROGENASE; DISULFIRAM; DOPAMINE; DOPAMINE BETA MONOOXYGENASE; GENOMIC DNA; NALTREXONE; NORADRENALIN;

ALCOHOL ABSTINENCE; ALCOHOLISM; ANXIETY; ARTHRALGIA; BLOOD SAMPLING; DEPRESSION; DIARRHEA; DNA POLYMORPHISM; DRUG EFFICACY; DRUG ERUPTION; DRUG MONITORING; DRUG SAFETY; DRUG TOLERABILITY; ENZYME ACTIVITY; ENZYME INHIBITION; FATIGUE; GENE FREQUENCY; GENE LOCATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HEADACHE; HEPATITIS; HETEROZYGOTE; HIGH RISK PATIENT; HOMOZYGOTE; HUMAN; INSOMNIA; LACTIC ACIDOSIS; LETTER; MYALGIA; NAUSEA; NORADRENERGIC SYSTEM; OUTCOME ASSESSMENT; PHARMACOGENETICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PRURITUS; RESTLESSNESS; SEXUAL DYSFUNCTION; SIDE EFFECT; TREATMENT RESPONSE; VOMITING;

ALCOHOL DETERRENTS; ALCOHOLISM; DISULFIRAM; DOPAMINE BETA-HYDROXYLASE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECURRENCE;

EID: 84863671257     PISSN: 02710749     EISSN: 1533712X     Source Type: Journal    
DOI: 10.1097/JCP.0b013e31825ddbe6     Document Type: Letter

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