Effect of residual water and microwave heating on the half-life of the reagents and reactive intermediates in peptide synthesis

Chemistry - A European Journal

Volumn 18, Issue 29, 2012, Pages 9024-9031

  Pernille Tofteng, A ^a   Pedersen, Søren L ^a   Staerk, Dan ^a   Jensen, Knud J ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

microwave chemistry; NMR spectroscopy; peptides; reactive intermediates; water

Indexed keywords

ACTIVATED ESTER; AMIDE BOND; ELECTROPHILIC REAGENTS; ELEVATED TEMPERATURE; MICROWAVE CHEMISTRY; PEPTIDE CHAIN; PEPTIDE SYNTHESIS; REACTIVE INTERMEDIATE; RESIDUAL WATERS; SMALL MOLECULES; SOLID PHASE PEPTIDE SYNTHESIS; SYSTEMATIC STUDY;

ACYLATION; AMIDES; ESTERIFICATION; ESTERS; MICROWAVE HEATING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES; REACTION INTERMEDIATES; WATER;

BIOSYNTHESIS;

DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; PEPTIDE; SOLVENT;

ARTICLE; CHEMISTRY; HALF LIFE TIME; HEATING; MICROWAVE RADIATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS;

HALF-LIFE; HEATING; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MICROWAVES; PEPTIDES; SOLVENTS;

EID: 84863653629     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201200711     Document Type: Article

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