Filament compliance influences cooperative activation of thin filaments and the dynamics of force production in skeletal muscle

PLoS Computational Biology

Volumn 8, Issue 5, 2012, Pages

  Tanner, Bertrand C W ^a   Daniel, Thomas L ^b,c   Regnier, Michael ^b  

^a UNIVERSITY OF VERMONT   (United States)

^b University of Washington   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINARY ALLOYS; KINETICS; MECHANISMS; MUSCLE; PROTEINS; STIFFNESS;

CA 2+; COOPERATIVITY; HIGHLY COOPERATIVES; MECHANICAL; MUSCLE CONTRACTIONS; SKELETAL MUSCLE; STRIATED MUSCLES; THIN FILAMENTS; TROPOMYOSIN; TROPONIN;

CHEMICAL ACTIVATION;

CALCIUM ION; TROPONIN; CALCIUM; MOLECULAR MOTOR;

ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM BINDING; CELL ACTIVATION; CELL INTERACTION; CONTROLLED STUDY; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; MUSCLE CONTRACTION; MUSCLE FORCE; NONHUMAN; PROBABILITY; PSOAS MUSCLE; RABBIT; SARCOMERE; SENSITIVITY ANALYSIS; THIN FILAMENT; ACTIN FILAMENT; ANIMAL; BIOLOGICAL MODEL; CALCIUM SIGNALING; COMPUTER SIMULATION; HUMAN; MECHANICAL STRESS; METABOLISM; PHYSIOLOGY; SKELETAL MUSCLE;

ORYCTOLAGUS CUNICULUS;

ACTIN CYTOSKELETON; ANIMALS; CALCIUM; CALCIUM SIGNALING; COMPUTER SIMULATION; HUMANS; MODELS, BIOLOGICAL; MOLECULAR MOTOR PROTEINS; MUSCLE CONTRACTION; MUSCLE, SKELETAL; SARCOMERES; STRESS, MECHANICAL;

EID: 84863651301     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002506     Document Type: Article

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