State-dependent inhibition of sodium channels by local anesthetics: A 40-year evolution

Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology

Volumn 6, Issue 2, 2012, Pages 120-127

  Wang, G K ^a   Strichartz, G R ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Drug binding; Local anesthetics; Modulated receptor; Sodium channel

Indexed keywords

AMINO ACID; ANTIARRHYTHMIC AGENT; BENZOCAINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; SODIUM CHANNEL NAV1.1; SODIUM CHANNEL NAV1.2; SODIUM CHANNEL NAV1.3; SODIUM CHANNEL NAV1.4; SODIUM CHANNEL NAV1.5; SODIUM CHANNEL NAV1.6; SODIUM CHANNEL NAV1.7; SODIUM CHANNEL NAV1.8; SODIUM CHANNEL NAV1.9; VOLTAGE GATED SODIUM CHANNEL;

AMINO TERMINAL SEQUENCE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; DEPOLARIZATION; DRUG BINDING SITE; DRUG MECHANISM; DRUG PROTEIN BINDING; ERYTHROMELALGIA; FAMILIAL DISEASE; HUMAN; HYDROPHILICITY; HYDROPHOBICITY; LONG QT SYNDROME; MOLECULAR BIOLOGY; MYOCLONUS EPILEPSY; NONHUMAN; PERIODIC PARALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN STRUCTURE; REVIEW; SODIUM CURRENT;

EID: 84863643006     PISSN: 19907478     EISSN: 19907494     Source Type: Journal    
DOI: 10.1134/S1990747812010151     Document Type: Review

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