A role for 12R-lipoxygenase in MUC5AC expression by respiratory epithelial cells

European Respiratory Journal

Volumn 40, Issue 3, 2012, Pages 714-723

  Garcia Verdugo, Ignacio ^a,b,c   BenMohamed, Fatima ^a,b   Tattermusch, Sonja ^a,b   Leduc, Dominique ^a,b   Charpigny, Gilles ^e   Chignard, Michel ^a,b   Ollero, Mario ^d   Touqui, Lhousseine ^a,b  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

^e INRA Institut National de la Recherche Agronomique   (France)

Author keywords

Eicosanoids; Lipoxygenase; MUC5AC; Mucins

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; ARACHIDONATE 12 LIPOXYGENASE; ICOSANOID; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; LIPOXYGENASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MUCIN 2; MUCIN 5AC; MUCIN 5B; PHORBOL 13 ACETATE 12 MYRISTATE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; INFLAMMATORY DISEASE; LUNG ALVEOLUS EPITHELIUM; LUNG DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UPREGULATION;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ARACHIDONATE 12-LIPOXYGENASE; CARCINOGENS; CELL LINE; CYCLOOXYGENASE INHIBITORS; EPITHELIAL CELLS; GENE SILENCING; HUMANS; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; LIPOXYGENASE INHIBITORS; MAP KINASE SIGNALING SYSTEM; MUCIN 5AC; MUCIN-2; MUCIN-5B; MUCUS; PROTEIN TRANSPORT; RESPIRATORY MUCOSA; SP1 TRANSCRIPTION FACTOR; TETRADECANOYLPHORBOL ACETATE; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 84863629417     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00023111     Document Type: Article

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