Toll-like receptor 4 signaling promotes the immunosuppressive cytokine production of human cervical cancer

European Journal of Gynaecological Oncology

Volumn 33, Issue 3, 2012, Pages 291-294

  Cheng, Y X ^a   Qi, X Y ^a   Huang, J L ^a   Hu, M ^a   Zhou, L M ^a   Li, B S ^a   Xu, X X ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Cervical cancer; IL 6; TGF 1; TLR 4

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; MAJOR CLINICAL STUDY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; UTERINE CERVIX CANCER; WESTERN BLOTTING;

ACTINS; ADULT; AGED; APOPTOSIS; CARBOPLATIN; CELL PROLIFERATION; CELL SURVIVAL; FEMALE; HELA CELLS; HUMANS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MIDDLE AGED; NF-KAPPA B; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1; UTERINE CERVICAL NEOPLASMS;

EID: 84863623938     PISSN: 03922936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Schmausser B., Andrulis M., Endrich S., Muller-Hermelink H.K., Eck M.: "Toll-like receptors TLR4, TLR5 and TLR9 on gastric carcinoma cells: an implication for interaction with Helicobacter pylori". Int. J. Med. Microbiol., 2005, 295, 179.
2. Kelly M.G., Alvero A.B., Chen R., Silasi D.A., Abrahams V.M., Chan S. et al.: "TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer". Cancer Res., 2006, 66, 2859.
3. Droemann D., Albrecht D., Gerdes J., Ulmer A.J., Branscheid D., Vollmer E. et al.: "Human lung cancer cells express functionally active Toll-like receptor 9". Respir. Res., 2005, 6, 1.
4. Sun J., Wiklund F., Zheng S.L., Chang B., Balter K., Li L. et al.: "Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk". J. Natl. Cancer Inst., 2005, 97, 525.
5. Richards M., Tan S., Fong C.Y., Biswas A., Chan W.K., Bongso A.: "Comparative evaluation of various human feeders for prolonged undifferentiated growth of human embryonic stem". Stem. Cells., 2003, 21, 546.
6. Rakoff-Nahoum S., Medzhitov R.: "Toll-like receptors and cancer. Nat. Rev. Cancer, 2009, 9, 57.
7. Huang B., Zhao J., Unkeless J.C., Feng Z.H., Xiong H.: "TLR signaling by tumor and immune cells: a double-edged sword". Oncogene, 2008, 27, 218.
8. Akira S.: "Toll-like receptor signaling". J. Biol. Chem., 2003, 278, 38105.
9. He W., Liu Q., Wang L., Chen W., Li N., Cao X.: "TLR4 signaling promotes immune escape of human lung cancer cells by inducing immunosuppressive cytokines and apoptosis resistance". Mol. Immunol., 2007, 44, 2850.